KEGG   ORTHOLOGY: K03160Help
Entry
K03160                      KO                                     

Name
TNFRSF5, CD40
Definition
tumor necrosis factor receptor superfamily member 5
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04064  NF-kappa B signaling pathway
ko04514  Cell adhesion molecules (CAMs)
ko04620  Toll-like receptor signaling pathway
ko04672  Intestinal immune network for IgA production
ko05144  Malaria
ko05145  Toxoplasmosis
ko05166  HTLV-I infection
ko05169  Epstein-Barr virus infection
ko05202  Transcriptional misregulation in cancer
ko05310  Asthma
ko05320  Autoimmune thyroid disease
ko05322  Systemic lupus erythematosus
ko05330  Allograft rejection
ko05340  Primary immunodeficiency
ko05416  Viral myocarditis
Disease
H00086  Hyper IgM syndromes, autosomal recessive type
H00093  Combined immunodeficiencies (CIDs)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
   04514 Cell adhesion molecules (CAMs)
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
   04672 Intestinal immune network for IgA production
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
  Immune diseases
   05310 Asthma
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
   05322 Systemic lupus erythematosus
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
   05320 Autoimmune thyroid disease
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
   05330 Allograft rejection
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
   05340 Primary immunodeficiency
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
  Cardiovascular diseases
   05416 Viral myocarditis
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
  Infectious diseases
   05166 HTLV-I infection
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
   05169 Epstein-Barr virus infection
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
   05144 Malaria
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
   05145 Toxoplasmosis
    K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
Cytokine receptors [BR:ko04050]
 Tumor necrosis factor receptors
  TNF receptor superfamily
   K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
CD molecules [BR:ko04090]
 Proteins
  K03160  CD40; tumor necrosis factor receptor superfamily, member 5
BRITE hierarchy
Genes
HSA: 958(CD40)
PTR: 100615583(CD40)
PPS: 100974274(CD40)
GGO: 101126651(CD40)
PON: 100460237(CD40)
NLE: 100598599(CD40)
MCC: 707749(CD40)
MCF: 102118696(CD40)
CSAB: 103245053(CD40)
RRO: 104678812(CD40)
RBB: 108533323(CD40)
CJC: 100385800(CD40)
SBQ: 101037196(CD40)
MMU: 21939(Cd40)
RNO: 171369(Cd40)
CGE: 100770242(Cd40)
NGI: 103751235(Cd40)
HGL: 101715501(Cd40)
CCAN: 109689299(Cd40)
OCU: 100349106(CD40)
TUP: 102489413(CD40)
CFA: 403469(CD40)
AML: 100476345(CD40)
UMR: 103669702(CD40)
ORO: 101381578(CD40)
FCA: 101085363(CD40)
PTG: 102972342(CD40)
AJU: 106968979(CD40)
BTA: 286849(CD40)
BOM: 102274192(CD40)
BIU: 109567510(CD40)
PHD: 102320549(CD40)
CHX: 102183249(CD40)
OAS: 443232(CD40)
SSC: 397395(CD40)
CFR: 102510463(CD40)
CDK: 105087849(CD40)
BACU: 103015045(CD40)
LVE: 103071515(CD40)
OOR: 101278975(CD40)
ECB: 100034049(CD40)
EPZ: 103551918(CD40)
EAI: 106843047(CD40)
MYB: 102261551(CD40)
MYD: 102764122(CD40)
HAI: 109379888(CD40)
RSS: 109457090(CD40)
PALE: 102890443(CD40)
LAV: 100666178(CD40)
TMU: 101345594
MDO: 100022240(CD40)
SHR: 100935349(CD40)
GGA: 395385(CD40)
MGP: 104914080(CD40)
CJO: 107323159(CD40)
APLA: 101793419(CD40)
ACYG: 106047117(CD40)
TGU: 100220945(CD40)
GFR: 102042563(CD40)
FAB: 101814566(CD40)
PHI: 102112115(CD40)
PMAJ: 107213230(CD40)
CCW: 104687864(CD40)
FPG: 101913161(CD40)
FCH: 102059987(CD40)
CLV: 102087204(CD40)
EGZ: 104127954(CD40)
AAM: 106497584(CD40)
ASN: 102368316(CD40)
AMJ: 102563086(CD40)
CMY: 102941434(CD40)
CPIC: 101935395(CD40)
ACS: 103281538
PVT: 110086225(CD40)
PBI: 103064466(CD40)
GJA: 107108043(CD40)
XLA: 108701036(cd40.L) 108702730
XTR: 100270675(cd40)
NPR: 108789107(CD40)
DRE: 100270764(cd40)
IPU: 108276426
AMEX: 111194086
TRU: 100271746(cd40)
XMA: 102228192
PRET: 103467842(tnfrsf18)
NFU: 107390437
CSEM: 103385708(tnfrsf9)
HCQ: 109510660(tnfrsf9) 109513557
SASA: 100196207(tnr5) 106567123
ELS: 105013652
LCM: 102356863(CD40)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2475341
  Authors
Stamenkovic I, Clark EA, Seed B
  Title
A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.
  Journal
EMBO J 8:1403-10 (1989)
  Sequence
[hsa:958]
Reference
  Authors
Elgueta R, Benson MJ, de Vries VC, Wasiuk A, Guo Y, Noelle RJ
  Title
Molecular mechanism and function of CD40/CD40L engagement in the immune system.
  Journal
Immunol Rev 229:152-72 (2009)
DOI:10.1111/j.1600-065X.2009.00782.x
Reference
  Authors
Eliopoulos AG, Wang CC, Dumitru CD, Tsichlis PN
  Title
Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40.
  Journal
EMBO J 22:3855-64 (2003)
DOI:10.1093/emboj/cdg386
  Sequence
[mmu:21939]

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