KEGG ORTHOLOGY: K03239

ORTHOLOGY: K03239

Entry

K03239 KO

Name

EIF2B1

Definition

translation initiation factor eIF-2B subunit alpha

Pathway

ko03013

RNA transport

Disease

H00869

Leukoencephalopathy with vanishing white matter

Brite

KEGG Orthology (KO) [BR:ko00001]
Genetic Information Processing
  Translation
   03013 RNA transport
    K03239  EIF2B1; translation initiation factor eIF-2B subunit alpha
Translation factors [BR:ko03012]
Eukaryotic Type
  Initiation factors
   eIF-2B
    K03239  EIF2B1; translation initiation factor eIF-2B subunit alpha

Other DBs

COG:

COG0182

GO:

0003743

Genes

HSA:	1967(EIF2B1)
PTR:	467184(EIF2B1)
PPS:	100975849(EIF2B1)
GGO:	101140455(EIF2B1)
PON:	100172592(EIF2B1)
MCC:	705438(EIF2B1)
MMU:	209354(Eif2b1)
RNO:	64514(Eif2b1)
CFA:	477447(EIF2B1)
AML:	100473244
FCA:	101100158(EIF2B1)
BTA:	516670(EIF2B1)
SSC:	100156140(EIF2B1)
ECB:	100059129
MDO:	100024001
SHR:	100934325(EIF2B1)
OAA:	100076136
GGA:	100857736
MGP:	100539625
TGU:	100225688(EIF2B1)
ACS:	100558685
XLA:	414553(eif2b1)
XTR:	550040(eif2b1)
DRE:	100151592 415150(eif2b1)
TRU:	101068001
OLA:	101161422
BFO:	BRAFLDRAFT_114409
SPU:	578099
DME:	Dmel_CG7883(eIF2B-alpha)
DPO:	Dpse_GA20657
DAN:	Dana_GF16217
DER:	Dere_GG11983
DPE:	Dper_GL13494
DSE:	Dsec_GM12201
DSI:	Dsim_GD17524
DWI:	Dwil_GK14086
DYA:	Dyak_GE10409
DGR:	Dgri_GH22202
DMO:	Dmoj_GI21971
DVI:	Dvir_GJ14332
AGA:	AgaP_AGAP003650
AAG:	AaeL_AAEL010251 AaeL_AAEL014262
CQU:	CpipJ_CPIJ002708
AME:	409118(eIF2B-alpha)
NVI:	100113908(NV14305)
TCA:	660145
API:	100166113
PHU:	Phum_PHUM259540
ISC:	IscW_ISCW024266
CEL:	CELE_ZK1098.4
CBR:	CBG10057
BMY:	Bm1_21890
TSP:	Tsp_00298
SMM:	Smp_084900
NVE:	NEMVE_v1g246207
HMG:	100215587
TAD:	TRIADDRAFT_20160
AQU:	100633775
ATH:	AT1G53880 AT1G53900 AT1G72340
ALY:	ARALYDRAFT_476363 ARALYDRAFT_682509
GMX:	100799015 100808764
MTR:	MTR_8g023040
CSV:	101211420
RCU:	RCOM_0417980
POP:	POPTR_414197 POPTR_584158
VVI:	100244672
OSA:	4352258
DOSA:	Os12t0497400-01(Os12g0497400)
BDI:	100824322
SBI:	SORBI_08g015410(SORBIDRAFT_08g015410)
ZMA:	100283573(gpm628)
SMO:	SELMODRAFT_131440
PPP:	PHYPADRAFT_132085 PHYPADRAFT_165754 PHYPADRAFT_185227
CRE:	CHLREDRAFT_596(EIF2Ba)
VCN:	VOLCADRAFT_108022(eif2Ba)
CME:	CMK064C CMR269C
SCE:	YKR026C(GCN3)
AGO:	AGOS_AFR084C
KLA:	KLLA0F13970g
LTH:	KLTH0D03234g
PPA:	PAS_chr4_0032
VPO:	Kpol_1016p16
ZRO:	ZYRO0F01870g
CGR:	CAGL0L03003g
NDI:	NDAI_0B05090(NDAI0B05090)
DHA:	DEHA2F21934g
PIC:	PICST_61090(GCN3)
PGU:	PGUG_00365
LEL:	LELG_05456
CAL:	CaO19.6904(GCN3) CaO19_6904(CaJ7_0138)
CTP:	CTRG_04854
CDU:	CD36_71080
YLI:	YALI0C18161g
CLU:	CLUG_05669
NCR:	NCU04344
SMP:	SMAC_01798
PAN:	PODANSg6158
MGR:	MGG_06077
FGR:	FG05648.1
NHE:	NECHADRAFT_62701
SSL:	SS1G_08344
BFU:	BC1G_03064
ANI:	AN0167.2
NFI:	NFIA_075930
AFM:	AFUA_5G11340
AOR:	AOR_1_1260014(AO090026000705)
ANG:	ANI_1_626164(An18g04650)
AFV:	AFLA_132570
ACT:	ACLA_014420
PCS:	Pc21g06160
CIM:	CIMG_09134
CPW:	CPC735_015550
URE:	UREG_05182
ABE:	ARB_03047
TVE:	TRV_03014
PNO:	SNOG_14011
PTE:	PTT_07450
TML:	GSTUM_00004384001
SPO:	SPCC11E10.07c
CNE:	CNC01730
CNB:	CNBC5530
PPL:	POSPLDRAFT_134853
LBC:	LACBIDRAFT_145994
MPR:	MPER_09897
CCI:	CC1G_04271
SCM:	SCHCODRAFT_50764
UMA:	UM03171.1
MGL:	MGL_1363
MBR:	MONBRDRAFT_19405
NGR:	NAEGRDRAFT_82768
DDI:	DDB_G0283309 DDB_G0288961(eIF2b1)
DPP:	DICPUDRAFT_88551
EHI:	EHI_096380(6.t00034)
EDI:	EDI_092370
PFA:	PF08_0009
PFD:	PFDG_00033
PFH:	PFHG_02759
PYO:	PY07384
PCB:	PC000609.02.0
PBE:	PB000468.03.0
PKN:	PKH_050240
PVX:	PVX_088930
CPV:	cgd1_1860
CHO:	Chro.10211
TGO:	TGME49_011230
TET:	TTHERM_00787070
PTM:	GSPATT00015208001
TBR:	Tb927.6.1280(Tb06.3A7.830)
TCR:	503971.40 507603.20 509429.90
LMA:	LMJF_12_0010
LIF:	LINJ.12.0001
LDO:	LDBPK_120010
LMI:	LMXM_12_0010
LBZ:	LBRM_12_0020
GLA:	GL50803_91911
TVA:	TVAG_118970
PTI:	PHATRDRAFT_10674
TPS:	THAPSDRAFT_264824
PIF:	PITG_18518
MJA:	MJ_0454
MMP:	MMP1618(aIF-2B_I)
MMQ:	MmarC5_1791
MTH:	MTH1872
MST:	Msp_1023
MKA:	MK0335(GCN3)
TAC:	Ta1212
TVO:	TVN1252
PTO:	PTO0261
PHO:	PH0702
PAB:	PAB2444(aIF-2BI)
PFU:	PF1349
TKO:	TK0556
APE:	APE_0686(mtnA)
SSO:	SSO2978(eiF2B)
SOL:	Ssol_0770
STO:	ST0922
SAI:	Saci_0539
SIS:	LS215_2546
SIA:	M1425_2373
SIM:	M1627_2451
SID:	M164_2380
SIY:	YG5714_2520
SIN:	YN1551_0386
SII:	LD85_2679
SIH:	SiH_2315
SIR:	SiRe_2263
MCN:	Mcup_1172
AHO:	Ahos_1988
PAI:	PAE0741
PIS:	Pisl_0663
PCL:	Pcal_2173
PAS:	Pars_0008
PYR:	P186_2236
POG:	Pogu_2484
CMA:	Cmaq_0396
TNE:	Tneu_0005
TUZ:	TUZN_0446
TTN:	TTX_0740
VDI:	Vdis_0830
VMO:	VMUT_1676

» show all

Reference

PMID:16990799

Authors

Singh CR, Lee B, Udagawa T, Mohammad-Qureshi SS, Yamamoto Y, Pavitt GD, Asano K

Title

An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation.

Journal

EMBO J 25:4537-46 (2006)

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   COG (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (473)   
   KEGG GENES (214)   
   KEGG DGENES (18)   
   KEGG EGENES (163)   
   KEGG MGENES (78)   
Protein sequence (180)   
   UniProt (180)   
Literature (1)   
   PubMed (1)   
All databases (662)   

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