KEGG   ORTHOLOGY: K03362Help
Entry
K03362                      KO                                     

Name
FBXW1_11, BTRC, beta-TRCP
Definition
F-box and WD-40 domain protein 1/11
Pathway
Oocyte meiosis
Ubiquitin mediated proteolysis
Wnt signaling pathway
Hedgehog signaling pathway
Hippo signaling pathway
Circadian rhythm
Shigellosis
Module
M00380  
SCF-BTRC complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
   04340 Hedgehog signaling pathway
    K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
   04390 Hippo signaling pathway
    K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
 Organismal Systems
  Environmental adaptation
   04710 Circadian rhythm
    K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
 Human Diseases
  Infectious diseases
   05131 Shigellosis
    K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00380  SCF-BTRC complex
     K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  multi subunit Ring-finger type E3
   SCF complex
    target recognizing subunit (F-box)
     K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centrosomal proteins
   Centrosome duplication proteins
    Regulators of centriole replication
     K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
BRITE hierarchy
Genes
HSA: 
23291(FBXW11) 8945(BTRC)
PTR: 
450685(BTRC) 462263(FBXW11)
PPS: 
100976100(FBXW11) 100977066(BTRC)
GGO: 
101142383(FBXW11) 101152319(BTRC)
PON: 
100171847(BTRC) 100432610(FBXW11)
NLE: 
100583099(BTRC) 100605260(FBXW11)
MCC: 
708990(FBXW11)
MCF: 
102136827(BTRC) 102143687(FBXW11)
CJC: 
100389218(BTRC) 100402300(FBXW11)
MMU: 
103583(Fbxw11) 12234(Btrc)
RNO: 
303024(Fbxw11) 361765(Btrc)
CGE: 
NGI: 
103744000(Btrc) 103748186(Fbxw11)
HGL: 
101718253(Fbxw11) 101726740(Btrc)
OCU: 
100340737(FBXW11) 100350519(BTRC)
TUP: 
CFA: 
479291(FBXW11) 486851(BTRC)
AML: 
100470916(BTRC) 100479018(FBXW11)
UMR: 
103664495(FBXW11) 103678776(BTRC)
FCA: 
101094156(FBXW11) 101097596(BTRC)
PTG: 
102953972(BTRC) 102962015(FBXW11)
BTA: 
534072(BTRC) 540642(FBXW11)
BOM: 
102273208(FBXW11) 102280912(BTRC)
PHD: 
102318056(FBXW11) 102344320(BTRC)
CHX: 
102184871(BTRC) 102187079(FBXW11)
OAS: 
101101939(BTRC) 101107136(FBXW11)
SSC: 
100157842(BTRC)
CFR: 
102509669(BTRC) 102521888(FBXW11)
BACU: 
103003148(BTRC) 103005978(FBXW11)
LVE: 
103070169(BTRC) 103072434(FBXW11)
ECB: 
100069972(FBXW11) 100070200(BTRC)
MYB: 
102250477(BTRC) 102262850(FBXW11)
MYD: 
102752909(BTRC) 102759029(FBXW11)
PALE: 
102893556(FBXW11) 102895058(BTRC)
MDO: 
100029508(BTRC) 100031160(FBXW11)
SHR: 
100923383(FBXW11) 100925642(BTRC)
OAA: 
100076818(FBXW11) 100080584(BTRC)
GGA: 
416181(FBXW11) 423854(BTRC)
MGP: 
APLA: 
101795851(BTRC) 101796951(FBXW11)
TGU: 
100217770(FBXW11) 100220854(BTRC)
FAB: 
101812833(BTRC) 101812846(FBXW11)
PHI: 
102101586(BTRC) 102103643(FBXW11)
FPG: 
101914153(FBXW11) 101920782(BTRC)
FCH: 
102054729(BTRC) 102057588(FBXW11)
CLV: 
102083982(BTRC) 102096361(FBXW11)
ASN: 
AMJ: 
102569199(BTRC) 102572700(FBXW11)
PSS: 
102449762(BTRC) 102460007(FBXW11)
CMY: 
102932779(FBXW11) 102937665(BTRC)
ACS: 
100555677(btrc) 100566594(fbxw11)
PBI: 
103052099(BTRC) 103055313(FBXW11)
XLA: 
394362(btrc)
XTR: 
549140(btrc)
DRE: 
334373(fbxw11a) 406825(fbxw11b)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
445628(betaTrCP)
SPU: 
578954(btrc)
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
551517(slmb)
NVI: 
TCA: 
664308(slmb)
BMOR: 
API: 
PHU: 
CEL: 
CELE_K10B2.1(lin-23)
CBR: 
CBG02640(Cbr-lin-23)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
SMM: 
NVE: 
HMG: 
100199403(fbxw11)
TAD: 
AQU: 
100634006(Btrc)
RCU: 
YLI: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_1326154(AO090003000750) AOR_1_1920154(AO090003001079)
ANG: 
ANI_1_1076024(An02g07700) ANI_1_1890184(An04g05180)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
PPL: 
DSQ: 
PCO: 
SHS: 
PSQ: 
ADL: 
FME: 
GTR: 
MPR: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT117888(AGABI1DRAFT_117888) AGABI1DRAFT76048(AGABI1DRAFT_76048)
ABV: 
AGABI2DRAFT148368(AGABI2DRAFT_148368) AGABI2DRAFT209689(AGABI2DRAFT_209689)
CPUT: 
SLA: 
PFP: 
MGL: 
PGR: 
MLR: 
WSE: 
MBR: 
ACAN: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Shirogane T, Jin J, Ang XL, Harper JW
  Title
SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein.
  Journal
J Biol Chem 280:26863-72 (2005)
  Sequence
[hsa:23291]
Reference
  Authors
Suzuki H, Chiba T, Suzuki T, Fujita T, Ikenoue T, Omata M, Furuichi K, Shikama H, Tanaka K
  Title
Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for  signal-dependent ubiquitination.
  Journal
J Biol Chem 275:2877-84 (2000)
  Sequence
[hsa:8945 23291]

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