KEGG ORTHOLOGY: K03680

ORTHOLOGY: K03680

Entry

K03680 KO

Name

EIF2B4

Definition

translation initiation factor eIF-2B subunit delta

Pathway

ko03013

RNA transport

Disease

H00869

Leukoencephalopathy with vanishing white matter

Brite

KEGG Orthology (KO) [BR:ko00001]
Genetic Information Processing
  Translation
   03013 RNA transport
    K03680  EIF2B4; translation initiation factor eIF-2B subunit delta
Translation factors [BR:ko03012]
Eukaryotic Type
  Initiation factors
   eIF-2B
    K03680  EIF2B4; translation initiation factor eIF-2B subunit delta

Other DBs

COG:

COG1184

GO:

0003743

Genes

HSA:	8890(EIF2B4)
PTR:	459099(EIF2B4)
PPS:	100992030(EIF2B4)
GGO:	101145747(EIF2B4)
PON:	100441987(EIF2B4)
MCC:	700322(EIF2B4)
MMU:	13667(Eif2b4)
RNO:	117019(Eif2b4)
CFA:	475702(EIF2B4)
AML:	100464883
FCA:	101098945(EIF2B4)
BTA:	521926(EIF2B4)
SSC:	100736566
ECB:	100055283(EIF2B4)
MDO:	100031109
SHR:	100931405(EIF2B4)
OAA:	100077244
GGA:	425800(EIF2B4)
MGP:	100547315
TGU:	100230981(EIF2B4)
ACS:	100553352
XLA:	496301(eif2b4)
XTR:	779817(eif2b4)
DRE:	541548(eif2b4)
TRU:	101065686
OLA:	101162495
BFO:	BRAFLDRAFT_240825
CIN:	100187323
SPU:	584767
DME:	Dmel_CG10315(eIF2B-delta)
DPO:	Dpse_GA10239
DAN:	Dana_GF13053
DER:	Dere_GG22851
DPE:	Dper_GL16909
DSE:	Dsec_GM16009
DSI:	Dsim_GD11760
DWI:	Dwil_GK23180
DYA:	Dyak_GE14287
DGR:	Dgri_GH21224
DMO:	Dmoj_GI20509
DVI:	Dvir_GJ22361
AGA:	AgaP_AGAP005937
AAG:	AaeL_AAEL012514
CQU:	CpipJ_CPIJ006915
AME:	724123
NVI:	100122371(NV16510)
TCA:	664566
API:	100168746
PHU:	Phum_PHUM546670
ISC:	IscW_ISCW011151
CEL:	CELE_F11A3.2
CBR:	CBG19294
BMY:	Bm1_32770
SMM:	Smp_166550
NVE:	NEMVE_v1g104343 NEMVE_v1g174250
HMG:	100198000
TAD:	TRIADDRAFT_31911
AQU:	100631406
ATH:	AT2G44070 AT5G38640
ALY:	ARALYDRAFT_494105
GMX:	100775998 100785938 100795256 100818977
MTR:	MTR_067s0078
CSV:	101215104
RCU:	RCOM_1569830
POP:	POPTR_837024
VVI:	100243979 100246278
OSA:	4333565 4352805
DOSA:	Os03t0645200-01(Os03g0645200) Os12t0617100-01(Os12g0617100)
BDI:	100824770
SBI:	SORBI_01g013530(SORBIDRAFT_01g013530) SORBI_08g021810(SORBIDRAFT_08g021810)
ZMA:	100304117
SMO:	SELMODRAFT_31552 SELMODRAFT_75538
CRE:	CHLREDRAFT_108477(EIF2B)
VCN:	VOLCADRAFT_55746(eif2B)
OLU:	OSTLU_42770
OTA:	Ot05g04300
CME:	CMT047C
SCE:	YGR083C(GCD2)
AGO:	AGOS_AEL322W
ERC:	Ecym_2610
KLA:	KLLA0F08327g
LTH:	KLTH0F10846g
PPA:	PAS_chr2-2_0275
VPO:	Kpol_284p5
ZRO:	ZYRO0C17600g
CGR:	CAGL0K01045g
NCS:	NCAS_0E01220(NCAS0E01220)
NDI:	NDAI_0G01430(NDAI0G01430)
TPF:	TPHA_0J01130(TPHA0J01130)
TBL:	TBLA_0C02430(TBLA0C02430)
TDL:	TDEL_0C05500(TDEL0C05500)
KAF:	KAFR_0K01450(KAFR0K01450)
DHA:	DEHA2F02772g
PIC:	PICST_33562
PGU:	PGUG_02247
LEL:	LELG_03043
CAL:	CaO19.14068(GCD2) CaO19.6776(GCD2)
CTP:	CTRG_05625
CDU:	CD36_87160
COT:	CORT_0C00170
YLI:	YALI0E00198g
CLU:	CLUG_05271
NCR:	NCU01468
SMP:	SMAC_07037
PAN:	PODANSg8317
TTT:	THITE_2107382
MTM:	MYCTH_2301163
FGR:	FG06096.1
NHE:	NECHADRAFT_63657
VAL:	VDBG_07547
SSL:	SS1G_03588
BFU:	BC1G_08380
ANI:	AN6864.2
NFI:	NFIA_074060
AFM:	AFUA_5G13040
AOR:	AOR_1_754094(AO090120000424)
AFV:	AFLA_094070
ACT:	ACLA_016020
PCS:	Pc21g08090
CIM:	CIMG_09272
CPW:	CPC735_016690
PBL:	PAAG_02560
URE:	UREG_05021
ABE:	ARB_03364
TVE:	TRV_02889
AJE:	HCAG_02516
PNO:	SNOG_10248
PTE:	PTT_07674
ZTR:	MYCGRDRAFT_55269
TML:	GSTUM_00010167001
SPO:	SPAC21E11.06(tif224)
CNE:	CNG01390
CNB:	CNBG3390
CGI:	CGB_G4740C
PPL:	POSPLDRAFT_134855
MPR:	MPER_04080
CCI:	CC1G_00020
SCM:	SCHCODRAFT_63740
UMA:	UM06318.1
MGL:	MGL_0019
PGR:	PGTG_17464 PGTG_18515
MBR:	MONBRDRAFT_10853
NGR:	NAEGRDRAFT_59484
DDI:	DDB_G0290759(eIF2b4)
DPP:	DICPUDRAFT_5838
EHI:	EHI_042980(111.t00019)
EDI:	EDI_037850
CPV:	cgd3_3020
CHO:	Chro.30342
TET:	TTHERM_00931950
PTM:	GSPATT00037416001 GSPATT00039662001
TBR:	Tb11.39.0006
TCR:	509835.20
LIF:	LINJ_27_1090
LDO:	LDBPK_271090
LMI:	LMXM_27_1210
LBZ:	LBRM_27_1310
GLA:	GL50803_4838
TVA:	TVAG_071730
PTI:	PHATRDRAFT_14255
TPS:	THAPSDRAFT_26743
PIF:	PITG_13607
NHL:	Nhal_2211
NIS:	NIS_0570
HMR:	Hipma_1174
SLP:	Slip_0714
TPZ:	Tph_c27250
RRS:	RoseRS_3027
RCA:	Rcas_2147
CAG:	Cagg_2012
MJA:	MJ_0122
MFE:	Mefer_1167
MVU:	Metvu_0771
MFS:	MFS40622_0999
MIG:	Metig_0446
MAE:	Maeo_0673
MOK:	Metok_1427
MAC:	MA0379(eif2B2)
MBA:	Mbar_A0793
MMA:	MM_1606
MBU:	Mbur_1938
MMH:	Mmah_0172
MEV:	Metev_2236
MZH:	Mzhil_1979
MPY:	Mpsy_1650
MHZ:	Metho_2361
MTP:	Mthe_1262
MCJ:	MCON_0206
MHI:	Mhar_2272
MHU:	Mhun_2314
MLA:	Mlab_0557
MEM:	Memar_2067
MBG:	BN140_1619
MPI:	Mpet_0507
MBN:	Mboo_2432
MFO:	Metfor_0217
MPL:	Mpal_0257
MPD:	MCP_2142
RCI:	RRC408(eif2b2)
AFU:	AF2037(eif2BD)
APO:	Arcpr_1056 Arcpr_1242
AVE:	Arcve_0806 Arcve_1636
FPL:	Ferp_2476
HAL:	VNG1452G(eif2bd) VNG1853G(eif2ba)
HSL:	OE3082R(aif2d) OE3610R
HMA:	rrnAC0289(eif2BD1) rrnAC1956(eif2BD2)
HHI:	HAH_1030(eif2BD1) HAH_2467(eif2BD2)
HWA:	HQ2713A(tif2Ba)
HWC:	Hqrw_3064(tif2Ba)
NPH:	NP3202A(tif2Ba_1)
NMO:	Nmlp_1786(tif2Bd)
HLA:	Hlac_2269 Hlac_2279
HMU:	Hmuk_2477 Hmuk_2762
HTU:	Htur_0571 Htur_1571
NMG:	Nmag_2966 Nmag_3347
HVO:	HVO_0966 HVO_2706(tif2Bd)
HME:	HFX_0963 HFX_2718(eif2BD2)
HJE:	HacjB3_07320
HBO:	Hbor_11610 Hbor_21590
HXA:	Halxa_1680 Halxa_3170
NAT:	NJ7G_3278 NJ7G_4171
NPE:	Natpe_2580 Natpe_3491
NGE:	Natgr_1133 Natgr_3633
HRU:	Halru_1540
NOU:	Natoc_0402 Natoc_1497
TAC:	Ta0910
TVO:	TVN0949
PTO:	PTO0527
TAR:	TALC_00199
PHO:	PH0208 PH0440
PAB:	PAB1306 PAB2402
PFU:	PF0122 PF0475
PFI:	PFC_01490 PFC_07590
PYN:	PNA2_0724 PNA2_1072
PYA:	PYCH_16630 PYCH_18570
PYS:	Py04_0275 Py04_0628
TKO:	TK0185 TK1047
TON:	TON_0637 TON_1296
TGA:	TGAM_1633 TGAM_1668(eIF-2BII)
TSI:	TSIB_0488 TSIB_0548
TBA:	TERMP_00456 TERMP_01301
THE:	GQS_01810 GQS_08985
THA:	TAM4_1574 TAM4_1733
THM:	CL1_0084 CL1_1398
ABI:	Aboo_0331
ACF:	AciM339_0726
APE:	APE_1047.1
SMR:	Smar_1357 Smar_1358
SHC:	Shell_1087 Shell_1088
DKA:	DKAM_0459 DKAM_0460
DMU:	Desmu_0715 Desmu_0716
DFD:	Desfe_0598 Desfe_0599
TAG:	Tagg_0676 Tagg_0677
THG:	TCELL_1140 TCELL_1141
HBU:	Hbut_0498 Hbut_0499
PAI:	PAE1244
PIS:	Pisl_1289
PCL:	Pcal_1377
PAS:	Pars_0288
PYR:	P186_2611
POG:	Pogu_2167
CMA:	Cmaq_1951
TNE:	Tneu_0261
TUZ:	TUZN_1205
TTN:	TTX_0076(GCD2)
VDI:	Vdis_1726
VMO:	VMUT_0175
TPE:	Tpen_0384 Tpen_0385
ASC:	ASAC_0502
CLG:	Calag_1023
KCR:	Kcr_0991
HAH:	Halar_1813 Halar_2167

» show all

Reference

PMID:16990799

Authors

Singh CR, Lee B, Udagawa T, Mohammad-Qureshi SS, Yamamoto Y, Pavitt GD, Asano K

Title

An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation.

Journal

EMBO J 25:4537-46 (2006)

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   COG (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (782)   
   KEGG GENES (328)   
   KEGG DGENES (23)   
   KEGG EGENES (196)   
   KEGG MGENES (235)   
Protein sequence (279)   
   UniProt (279)   
Literature (1)   
   PubMed (1)   
All databases (1070)   

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