KEGG ORTHOLOGY: K03875

ORTHOLOGY: K03875

Entry

K03875                      KO

Symbol

SKP2, FBXL1

Name

F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)

Pathway

map04068

FoxO signaling pathway

map04110

Cell cycle

map04120

Ubiquitin mediated proteolysis

map04150

mTOR signaling pathway

map05169

Epstein-Barr virus infection

map05200

Pathways in cancer

map05203

Viral carcinogenesis

map05222

Small cell lung cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
   04150 mTOR signaling pathway
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
   05203 Viral carcinogenesis
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   SCF complex
    Target recognizing subunit (F-box)
     K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)

Genes

HSA:	6502(SKP2)

PTR:	471570(SKP2)

PPS:	100978721(SKP2)

GGO:	101134461(SKP2)

PON:	100432371(SKP2)

NLE:	100586655(SKP2)

HMH:	116456910(SKP2)

MCC:	700617(SKP2)

MCF:	102114882(SKP2)

MTHB:

126957088

MNI:	105473080(SKP2)

CSAB:

103215131(SKP2)

CATY:

105583426(SKP2)

PANU:

101000264(SKP2)

TGE:	112625831(SKP2)

MLEU:

105555423(SKP2)

RRO:	104662024(SKP2)

RBB:	108535053(SKP2)

TFN:	117065023(SKP2)

PTEH:

111545519(SKP2)

CANG:

105513491(SKP2)

CJC:	100393248(SKP2)

SBQ:

101041621

CIMI:

108317630(SKP2)

CSYR:

103251986(SKP2)

MMUR:

105855459(SKP2)

LCAT:

123648646(SKP2)

PCOQ:

105814809(SKP2)

OGA:	100942708(SKP2)

MMU:	27401(Skp2)

MCAL:

110310405(Skp2)

MPAH:

110328844(Skp2)

RNO:	294790(Skp2)

MCOC:

116083772(Skp2)

ANU:	117724054(Skp2)

MUN:	110566051(Skp2)

CGE:	100771396(Skp2)

MAUA:

101837348(Skp2)

PROB:

127220633(Skp2)

PLEU:

114681382 114697360(Skp2)

MORG:

121433099(Skp2) 121439825 121445087 121445657 121445658

MFOT:

126488277 126499685

AAMP:

119805439 119805441 119805442 119809590(Skp2)

NGI:	103741317(Skp2)

HGL:	101706248(Skp2)

CPOC:

100720705(Skp2)

CCAN:

109702695(Skp2)

DORD:

105987402(Skp2)

DSP:	122117008(Skp2)

PLOP:

125367687(Skp2)

NCAR:

124986905

MMMA:

107151118(Skp2)

OCU:	100338447 100342452

OPI:	101531086(SKP2)

TUP:	102497164(SKP2)

GVR:	103597559(SKP2)

CFA:	489228(SKP2)

CLUD:

112652849(SKP2)

VVP:	112933526(SKP2)

VLG:	121488336(SKP2)

NPO:	129509822(SKP2)

AML:	100480437(SKP2)

UMR:	103664708(SKP2)

UAH:	113260895(SKP2)

UAR:	123785481(SKP2)

ELK:

111140933

LLV:

125099857

MPUF:

101682622(SKP2)

MNP:	132028248(SKP2)

MLK:	131831657(SKP2)

NVS:	122895358(SKP2)

ORO:	101383205(SKP2)

EJU:	114204772(SKP2)

ZCA:	113928995(SKP2)

MLX:	118006346 118006475

NSU:	110586053(SKP2)

LWW:

102736340

FCA:	101099275(SKP2)

PYU:	121043524(SKP2)

PCOO:

112861348(SKP2)

PBG:	122494612(SKP2)

PVIV:

125157110(SKP2)

LRUF:

124522217

PTG:	102964396(SKP2)

PPAD:

109260099(SKP2)

PUC:

125934645

AJU:

106979642

HHV:	120244162(SKP2)

BTA:	519018(SKP2) 785617

BOM:	102269700(SKP2) 102277531

BIU:	109574865(SKP2) 109579088

BBUB:

102395935(SKP2)

BBIS:

104998552(SKP2)

CHX:	102172762(SKP2)

OAS:	101109483(SKP2)

BTAX:

128059172 128066055(SKP2)

ODA:	120879342(SKP2)

CCAD:

122454407(SKP2)

MBEZ:

129550007 129553317(SKP2)

SSC:	100329128(SKP2)

CFR:	102523584(SKP2)

CBAI:

105069411(SKP2)

CDK:	105086996(SKP2)

VPC:	102541169(SKP2)

BACU:

103007736(SKP2)

BMUS:

118892325(SKP2)

LVE:	103090160(SKP2)

OOR:	101274005(SKP2)

DLE:	111187525(SKP2)

PCAD:

102973239 102991021

PSIU:

116752049(SKP2)

NASI:

112406027(SKP2)

ECB:	100053697(SKP2)

EPZ:

103563536

EAI:	106824722(SKP2)

MYB:	102262715(SKP2)

MYD:	102770564(SKP2)

MMYO:

118655860(SKP2)

MLF:	102429293(SKP2)

PKL:	118703716(SKP2)

EFUS:

103298086(SKP2)

MNA:	107546230(SKP2)

DRO:	112321074(SKP2)

SHON:

118998776(SKP2)

AJM:	119037019(SKP2)

PDIC:

114497743(SKP2)

PHAS:

123824539(SKP2)

MMF:	118641733(SKP2)

PPAM:

129079051(SKP2)

HAI:	109387065(SKP2)

RFQ:	117025370(SKP2)

PALE:

102880695(SKP2)

PGIG:

120586194(SKP2)

PVP:	105307445(SKP2)

RAY:	107509711(SKP2)

TOD:	119261442(SKP2)

SARA:

101554118(SKP2)

SETR:

126001810(SKP2)

LAV:	100676976(SKP2)

TMU:

101348198

ETF:	101646103(SKP2)

DNM:	101439951(SKP2)

MDO:	100020421(SKP2)

GAS:	123231512(SKP2)

SHR:	100915218(SKP2)

AFZ:

127556614

PCW:	110214774(SKP2)

OAA:	103166602(SKP2)

GGA:	427437(SKP2)

PCOC:

116238633(SKP2)

MGP:	100542923(SKP2)

CJO:	107305844(SKP2)

TPAI:

128074559(SKP2)

LMUT:

125687015(SKP2)

NMEL:

110389514(SKP2)

APLA:

101802477(SKP2)

ACYG:

106036387(SKP2)

CATA:

118256634(SKP2)

AFUL:

116500511(SKP2)

TGU:	100217547(SKP2)

LSR:	110482530(SKP2)

SCAN:

103821008

PMOA:

120502538(SKP2)

OTC:	121343558(SKP2)

PRUF:

121352838(SKP2)

GFR:	102037500(SKP2)

FAB:	101810388(SKP2)

OMA:	130264793(SKP2)

PHI:	102109076(SKP2)

PMAJ:

107216438(SKP2)

CCAE:

111940976(SKP2)

CCW:	104686606(SKP2)

CBRC:

103612925(SKP2)

ETL:	114055031(SKP2)

ZAB:	102063901(SKP2)

ACHL:

103808307(SKP2)

SVG:	106852735(SKP2)

MMEA:

130572771(SKP2)

HRT:	120765927(SKP2)

FPG:	101911609(SKP2)

FCH:	102053148(SKP2)

CLV:	102084967(SKP2)

EGZ:	104133851(SKP2)

NNI:	104018639(SKP2)

PCRI:

104030830(SKP2)

PLET:

104624397(SKP2)

EHS:	104503068(SKP2)

PCAO:

104050010

ACUN:

113489833(SKP2)

TALA:

104365382(SKP2)

PADL:

103921478(SKP2)

AFOR:

103903877(SKP2)

ACHC:

115336928(SKP2)

HALD:

104315675(SKP2)

HLE:	104830611(SKP2)

AGEN:

126036152

GCL:

127027325

CCRI:

104167997

CMAC:

104486391(SKP2)

MUI:	104545905(SKP2)

BREG:

104640402(SKP2)

FGA:	104069982(SKP2)

GSTE:

104251056(SKP2)

LDI:	104354836(SKP2)

MNB:	103776949(SKP2)

OHA:	104337674(SKP2)

NNT:	104402803(SKP2)

SHAB:

115619493(SKP2)

DPUB:

104303135(SKP2)

PGUU:

104461929

ACAR:

104526443(SKP2)

CPEA:

104398599(SKP2)

AVIT:

104271097(SKP2)

CVF:	104294985(SKP2)

RTD:	128902479(SKP2)

CUCA:

104063836(SKP2)

TEO:

104369760

BRHI:

104489774(SKP2)

AAM:	106499538(SKP2)

AROW:

112976200(SKP2)

NPD:	112946216(SKP2)

TGT:

104570690

DNE:	112982167(SKP2)

SCAM:

104147787(SKP2)

ASN:	102367894(SKP2)

AMJ:	102558881(SKP2)

CPOO:

109307834(SKP2)

GGN:	109297897(SKP2)

PSS:	102445640(SKP2)

CMY:	102933431(SKP2)

CCAY:

125637254(SKP2)

DCC:	119855800(SKP2)

CPIC:

101935689(SKP2)

TST:	117879165(SKP2)

CABI:

116824574(SKP2)

MRV:	120408460(SKP2)

ACS:	100564206(skp2)

ASAO:

132766927(SKP2)

PVT:	110080059(SKP2)

SUND:

121922239(SKP2)

PBI:	103054864(SKP2)

PMUR:

107297968(SKP2)

CTIG:

120310021(SKP2)

TSR:	106557164(SKP2)

PGUT:

117679988(SKP2)

APRI:

131191714(SKP2)

PTEX:

113446198(SKP2)

NSS:	113411381(SKP2)

VKO:	123024013(SKP2)

PRAF:

128423312(SKP2)

ZVI:	118077117(SKP2)

HCG:	128344661(SKP2)

GJA:	107108086(SKP2)

STOW:

125436100(SKP2)

EMC:	129334299(SKP2)

XLA:	734901(skp2.L)

XTR:	100216169(skp2)

NPR:	108792651(SKP2)

RTEM:

120927590(SKP2)

BBUF:

120992178(SKP2)

BGAR:

122939079(SKP2)

MUO:	115462940(SKP2)

GSH:	117352642(SKP2)

DRE:	563708(skp2)

SRX:	107706432 107718976

SANH:

107681151 107703541

SGH:	107548167 107551629

CCAR:

109045264 109076410

CAUA:

113038625 113064272

CGIB:

127941621 127986261

PTET:

122326673(skp2)

LROH:

127152634(skp2)

OMC:	131528753(skp2)

PPRM:

120494628(skp2)

RKG:	130096485(skp2)

MAMB:

125253496(skp2)

CIDE:

127503905

MASI:

127428594 127431103

TROS:

130570465(skp2)

TDW:	130408151(skp2)

MANU:

129424419(skp2)

IPU:

108279378

IFU:	128622770(skp2)

PHYP:

113541502(skp2)

SMEO:

124397633(skp2)

TFD:	113634912(skp2)

TVC:	132860459(skp2)

AMEX:

103047278(skp2)

CMAO:

118819980(skp2)

EEE:	113574196(skp2)

CHAR:

105893344(skp2)

TRU:	101066648(skp2)

TFS:	130517534(skp2)

LCO:	104938172(skp2)

TBEN:

117478778(skp2)

CGOB:

115006030(skp2)

PGEO:

117444333(skp2) 117444335

GACU:

117542904(skp2)

EMAC:

134868420(skp2)

ELY:	117269393(skp2)

EFO:	125905915(skp2)

PLEP:

121959762(skp2)

SLUC:

116041399(skp2)

ECRA:

117959233(skp2)

ESP:	116704054(skp2)

PFLV:

114571071(skp2)

GAT:

120831654

PPUG:

119226275(skp2)

AFB:	129102453(skp2)

CLUM:

117740939(skp2)

PSWI:

130205111(skp2)

MSAM:

119914397(skp2)

SCHU:

122865389(skp2)

CUD:	121525283(skp2)

ALAT:

119029939(skp2)

MZE:	101475050(skp2)

ONL:	100695272(skp2)

OAU:	116315777(skp2)

OLA:	101156183(skp2)

OML:	112163437(skp2)

CSAI:

133454887(skp2)

XMA:	102229286(skp2)

XCO:	114150144(skp2)

XHE:	116723969(skp2)

PRET:

103474062(skp2)

PFOR:

103131313(skp2)

PLAI:

106956194(skp2)

PMEI:

106927045(skp2)

GAF:	122847133(skp2)

PPRL:

129354289

CVG:	107093937(skp2)

CTUL:

119780548(skp2)

GMU:	124872139(skp2)

NFU:	107375004(skp2)

KMR:	108228591(skp2)

ALIM:

106531672(skp2)

NWH:	119425005(skp2)

AOCE:

111574103(skp2)

MCEP:

124996351(skp2)

CSEM:

103389192 103389199

POV:	109647460(skp2)

SSEN:

122758576(skp2)

HHIP:

117771425(skp2)

HSP:	118098072(skp2)

SMAU:

118284506(skp2)

LCF:	108900731(skp2)

SDU:	111221206(skp2)

SLAL:

111648076(skp2)

XGL:	120806862(skp2)

HCQ:	109529111(skp2)

SSCV:

125979846

SBIA:

133490576(skp2)

PEE:	133401852 133413965(skp2)

PTAO:

133480038 133480041 133480043 133489974(skp2)

BPEC:

110161888(skp2)

MALB:

109960759(skp2)

BSPL:

114866419(skp2)

SJO:	128380407(skp2)

SASA:

106563829 106568170

STRU:

115149232(skp2)

OTW:

112257530

OMY:

110537145

OGO:

123999595

ONE:	115105866(skp2)

OKI:	109892486(skp2)

OKE:	118391435(skp2)

SALP:

111961421 111981396(skp2)

SNH:	120025561(skp2) 120044230

CCLU:

121573859 121582186

ELS:	105025175(skp2)

SFM:	108933818(skp2)

PKI:	111842164(skp2)

AANG:

118212239(skp2)

LOC:	102683784(skp2)

PSPA:

121304766 121318314

ARUT:

117409303 117421557(skp2)

PSEX:

120527290(skp2)

LCM:	102356499(SKP2)

RTP:	109923386(skp2)

CPLA:

122556303(skp2)

HOC:	132826348(skp2)

LERI:

129694395(skp2)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

SKO:

DME:	Dmel_CG9772(Skp2)

DER:

6552112

DSE:

6613812

DSI:	Dsimw501_GD19685(Dsim_GD19685)

DYA:	Dyak_GE25359

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI22887

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:	101893441 131801543

SCAC:

106080639

LCQ:

111690972

LSQ:	119609018 119614484 119614996

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ003639

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:	122631315 122631319

VCRB:

124426014 124426016

VVE:	124951699 124951703

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

122847388 122847889 122848867 122855153 122855394 122860464

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:	115879259 115884331

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_212958

BANY:

MJU:

VCD:

MCIX:

PMAC:

PPOT:

PXU:	106122494 106126037

PRAP:

ZCE:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105391422 105395933 105395934

PGW:

126379471

CCRN:

123290605

API:	100160074 100574783

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM040260

FOC:	113204821 113205756 113206717 113206745 113207325 113209149 113211511 113215176 113215554

TPAL:

117640645 117643161 117644960 117646904 117647115 117647171 117647967 117648092 117648336 117649402 117649484 117649901 117651666 117651711 117652804 117652821

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_39705

DMK:

116918361

DPZ:

124343264

PVM:	113826054 113826388

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:	111697035 111699764

LSM:

121129895

TCF:

131889794

PPOI:

119098374 119099252 119111651

DSV:

RSAN:

RMP:

VDE:

VJA:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

CEL:	CELE_F48E8.7(skpt-1)

CBR:	CBG_05188(Cbr-skpt-1)

CRQ:	GCK72_010539

LGI:	LOTGIDRAFT_162707

PVUL:

126818618

PCAN:

112574309

BGT:

106052054

GAE:	121368446 121374647

HRF:

124118386

HRJ:

124256749

CRG:	105332044 105334825

CVN:	111120632 111121135

CANU:

OED:

MYI:

PMAX:

MMER:

DPOL:

OBI:

OSN:

LAK:

NVE:

ATEN:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:	130629503 130629520 130629544

ATH:	AT1G21410(SKP2A) AT1G77000(SKP2B)

ALY:	9323729 9326504

CRB:	17896544 17900565

CSAT:

104702471 104715865 104743434 104751597 104756500 104776263

EUS:	EUTSA_v10008012mg EUTSA_v10018746mg

BRP:	103830576 103832158 103835748

BNA:	106354633 106376596 106377228 106390223 106425880 106440720 125574872

BOE:	106296844 106296874 106320805

RSZ:	108817317 108817460 108821994 108821995

THJ:	104804863 104810056 104812061

CPAP:

110818172

CIT:

102610462

CIC:	CICLE_v10001527mg

PVY:

116117187

MINC:

123203241 123229533

TCC:

18592471

GRA:	105769990 105774578 105783905 105797108 105799059

GHI:	107910407 107914131 107949523 107951467 107951990 107957709

GAB:	108464200 108476028 108480402

HSYR:

120155809 120206175 120218555

DZI:	111298713 111312230 111314993

EGR:

104449651

GMX:	100788845 100793275 100797840 100818928

GSJ:	114382553 114385121 114410360 114415475

PVU:	PHAVU_001G065400g PHAVU_009G133200g

VRA:	106763012 106778853

VAR:	108331909 108338715

VUN:	114163764 114193161

VUM:	124829513 124836521

CCAJ:

109789854 109815750

APRC:

113846879 113847982

MTR:	25482432 25489745

TPRA:

123896793

CAM:	101495232 101512090

PSAT:

127082717 127091052 127095036

VVO:

131596019

LJA:	Lj0g3v0152909.1(Lj0g3v0152909.1) Lj5g3v0369960.1(Lj5g3v0369960.1) Lj5g3v0369960.2(Lj5g3v0369960.2)

ADU:

107460595

AIP:

107605985

AHF:	112706000 112765536

LANG:

109327037 109328396 109344329

PCIN:

129294109 129298080

QSA:	O6P43_015091 O6P43_019830

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103436619 103444539

MSYL:

126586261 126623197

PXB:	103934815 103951113 103957904

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:	110634552 110645417

MESC:

110606678 110609224

POP:	7466433 7469194

PEU:	105107575 105127719

PALZ:

118027496 118029200

JRE:	108981368 109013670

CILL:

CAVE:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107775581 107783609

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:	111372283 111373167 111408723

EGT:

105963399

SSPL:

121756154 121756437 121774510 121779701 121780139 121781084

SMIL:

130992896 131003382 131011782

SHIS:

125207486 125218949 125222183

APAN:

127246913

HAN:	110873514 110878514 110886203 110934745 110936667 110936668 110936669 110942172

ECAD:

122579939 122590293

LSV:	111901930 111904151

CCAV:

112502665

DCR:	108204796 108210979

CSIN:

114282551 114285553

RVL:

131306583

AEW:	130757908 130786923 130787504

BVG:

104905903

SOE:

110782035

CQI:	110685901 110725768

ATRI:

130810351

MOF:

131161744

NNU:	104599558 104606717

MING:

122072968 122090525 122093994

TSS:	122639661 122667781

PSOM:

113346432 113356462

OSA:	4324993 4338850

DOSA:

Os01t0881900-01(Os01g0881900) Os05t0425700-01(Os05g0425700)

OBR:	102711806 102720653

OGL:	127774605 127782077

BDI:	100821602 100822312

ATS:	109741353 109743063

TDC:	119269956 119277966 119280222 119344814

TAES:

123056689 123062952 123071814 123080143 123133972 123182089

TUA:	125519001 125545595 125545597

LPER:

127313014 127345187

LRD:	124665579 124666461 124706470 124707878

SBI:	8058475 8063136

ZMA:	100274332 100274363

SITA:

101752546 101754500

SVS:	117849798 117858997

PVIR:

120665415 120673433 120698633 120708879

PHAI:

112884864 112895936

PDA:	103718718 103722202 120113029

EGU:	105037566 105045214

MUS:	103974333 103988146 104000225

ZOF:	121967256 121970132 121975224 122001399 122005719 122025690

DCT:

110116103

PEQ:

110024639

AOF:	109825128 109838057

MSIN:

131242631

NCOL:

116253264 116267102

ATR:

18436941

SMO:	SELMODRAFT_133097 SELMODRAFT_133180

PPP:	112279181 112288528 112289862

CSL:	COCSUDRAFT_55654

MBR:	MONBRDRAFT_34230

» show all

Reference

PMID:17962192

Authors

Nie L, Wu H, Sun XH

Title

Ubiquitination and degradation of Tal1/SCL are induced by notch signaling and depend on Skp2 and CHIP.

Journal

J Biol Chem 283:684-92 (2008)
DOI:10.1074/jbc.M704981200

Sequence

[hsa:6502]

Reference

PMID:16262255

Authors

Wang W, Nacusi L, Sheaff RJ, Liu X

Title

Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection.

Journal

Biochemistry 44:14553-64 (2005)
DOI:10.1021/bi051071j

Sequence

[hsa:6502]

Reference

PMID:12840033

Authors

Li X, Zhao Q, Liao R, Sun P, Wu X

Title

The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation.

Journal

J Biol Chem 278:30854-8 (2003)
DOI:10.1074/jbc.C300251200

Sequence

[hsa:6502]

Reference

PMID:7553852

Authors

Zhang H, Kobayashi R, Galaktionov K, Beach D

Title

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase.

Journal

Cell 82:915-25 (1995)
DOI:10.1016/0092-8674(95)90271-6

Sequence

[hsa:6502]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Gene (2339)   
   KEGG GENES (998)   
   KEGG MGENES (127)   
   RefGene (1209)   
   OC (5)   
Literature (4)   
   PubMed (4)   
All databases (2361)   

Download RDF

DBGET integrated database retrieval system