KEGG   ORTHOLOGY: K03934Help
Entry
K03934                      KO                                     

Name
NDUFS1
Definition
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]
Pathway
ko00190  Oxidative phosphorylation
ko01100  Metabolic pathways
ko04714  Thermogenesis
ko04723  Retrograde endocannabinoid signaling
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05010  Alzheimer's disease
ko05012  Parkinson's disease
ko05016  Huntington's disease
Module
M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Disease
H00473  Mitochondrial complex I deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Energy metabolism
   00190 Oxidative phosphorylation
    K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1
 Organismal Systems
  Nervous system
   04723 Retrograde endocannabinoid signaling
    K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1
  Environmental adaptation
   04714 Thermogenesis
    K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1
   05012 Parkinson's disease
    K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1
   05016 Huntington's disease
    K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1
KEGG modules [BR:ko00002]
 Structural complex
  Energy metabolism
   ATP synthesis
    M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
     K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.6  Acting on NADH or NADPH
   1.6.5  With a quinone or similar compound as acceptor
    1.6.5.3  NADH:ubiquinone reductase (H+-translocating)
     K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1
   1.6.99  With unknown physiological acceptors
    1.6.99.3  NADH dehydrogenase
     K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1
BRITE hierarchy
Other DBs
RN: R11945
GO: 0008137 0003954
TC: 3.D.1.6
Genes
HSA: 4719(NDUFS1)
PTR: 459896(NDUFS1)
PPS: 100967685(NDUFS1)
GGO: 101139264(NDUFS1)
PON: 100172962(NDUFS1)
NLE: 100581296(NDUFS1)
MCC: 706912(NDUFS1)
MCF: 101865238(NDUFS1)
CSAB: 103217702(NDUFS1)
RRO: 104653602(NDUFS1)
RBB: 108543433(NDUFS1)
CJC: 100413081(NDUFS1)
SBQ: 101037033(NDUFS1)
MMU: 227197(Ndufs1)
RNO: 301458(Ndufs1)
CGE: 100754223(Ndufs1) 100769705
NGI: 103744430(Ndufs1)
HGL: 101698993(Ndufs1)
CCAN: 109697500(Ndufs1)
OCU: 100341941(NDUFS1)
TUP: 102470342(NDUFS1)
CFA: 478880(NDUFS1)
AML: 100484187(NDUFS1)
UMR: 103659788(NDUFS1)
ORO: 101369334(NDUFS1)
FCA: 101100747(NDUFS1)
PTG: 102951216(NDUFS1)
AJU: 106976705(NDUFS1)
BTA: 288380(NDUFS1)
BOM: 102269675(NDUFS1)
BIU: 109569901(NDUFS1)
PHD: 102342767(NDUFS1)
CHX: 100861376(NDUFS1)
OAS: 101115434(NDUFS1)
SSC: 100516402(NDUFS1)
CFR: 102505428(NDUFS1)
CDK: 105099258(NDUFS1)
BACU: 103020178(NDUFS1)
LVE: 103073569(NDUFS1)
OOR: 101269912(NDUFS1)
ECB: 100066330(NDUFS1)
EPZ: 103556536(NDUFS1)
EAI: 106828149(NDUFS1)
MYB: 102251040(NDUFS1)
MYD: 102751403(NDUFS1)
HAI: 109388333(NDUFS1)
RSS: 109440172 109445016(NDUFS1)
PALE: 102885610(NDUFS1)
LAV: 100677530(NDUFS1)
TMU: 101354085
MDO: 100017188(NDUFS1)
SHR: 100914378(NDUFS1)
OAA: 100085312
GGA: 424102(NDUFS1)
MGP: 100540281(NDUFS1)
CJO: 107316600(NDUFS1)
APLA: 101805119(NDUFS1)
ACYG: 106030073(NDUFS1)
TGU: 100220458(NDUFS1)
GFR: 102041373(NDUFS1)
FAB: 101808800(NDUFS1)
PHI: 102099800(NDUFS1)
PMAJ: 107207473(NDUFS1)
CCW: 104693806(NDUFS1)
FPG: 101910410(NDUFS1)
FCH: 102049657(NDUFS1)
CLV: 102086968(NDUFS1)
EGZ: 104125080(NDUFS1)
AAM: 106492414(NDUFS1)
ASN: 102383959(NDUFS1)
AMJ: 102566976(NDUFS1)
PSS: 102448500(NDUFS1)
CMY: 102946143(NDUFS1)
CPIC: 101934729(NDUFS1)
ACS: 100565838(ndufs1)
PVT: 110072425(NDUFS1)
PBI: 103051990(NDUFS1)
GJA: 107114501(NDUFS1)
XLA: 108703063(ndufs1.S) 380000(ndufs1.L)
XTR: 100380019(ndufs1)
NPR: 108790353(NDUFS1)
DRE: 493605(ndufs1)
IPU: 108272721(ndufs1)
TRU: 101064163(ndufs1) 101065656
LCO: 104917974 104924418(ndufs1)
NCC: 104947520(ndufs1) 104952387
MZE: 101470413 101472159(ndufs1)
OLA: 101157518 101164519(ndufs1)
XMA: 102229581(ndufs1) 102234132
PRET: 103458080(ndufs1) 103475208
NFU: 107380909 107389979(ndufs1)
CSEM: 103389332(ndufs1)
LCF: 108881521(ndufs1) 108892916
HCQ: 109520905(ndufs1)
BPEC: 110165988(ndufs1)
SFM: 108942178(ndufs1)
LCM: 102351503(NDUFS1)
CMK: 103182876(ndufs1)
CIN: 100185471
SPU: 582178
APLC: 110989245
SKO: 100371345
DME: Dmel_CG2286(ND-75)
DER: Dere_GG17973(Dere_ND75)
DSI: Dsimw501_GD27646(Dsim_GD27646)
DYA: Dyak_GE17466(Dyak_ND75)
MDE: 101899436
AAG: 5576501
AME: 726035(Ndufs1)
BIM: 100744483
BTER: 100648930
SOC: 105201161
AEC: 105146361
ACEP: 105627818
PBAR: 105426281
HST: 105191934
CFO: 105256146
LHU: 105679989
PGC: 109860503
NVI: 100119153(Ndufs1)
TCA: 662618(nuoG)
DPA: 109536664
NVL: 108567061
API: 100162912
DNX: 107173125
ZNE: 110828157
FCD: 110847795
CEL: CELE_Y45G12B.1(nuo-5)
CBR: CBG06645(Cbr-nuo-5)
BMY: Bm1_52130
TSP: Tsp_07929
CRG: 105342980
MYI: 110465929
OBI: 106869655
SHX: MS3_05832
EPA: 110250242
ATH: AT5G37510(EMB1467)
CRB: 17877981
BRP: 103863727
BOE: 106342013
CPAP: 110809752
CIT: 102610171
TCC: 18601306
VRA: 106757688
VAR: 108329117
CCAJ: 109788701
CAM: 101498632
ADU: 107481037
LJA: Lj6g3v0409410.1(Lj6g3v0409410.1)
FVE: 101296235
PPER: 18784333
PAVI: 110771011
ZJU: 107417369
CSV: 101205189
CMO: 103496870
MCHA: 111013230
RCU: 8272194
JCU: 105645446
JRE: 108988010
VVI: 100246750
SLY: 101263481
SPEN: 107004525
SOT: 102594243(CI-76kD)
CANN: 107850552
NSY: 104211220
NTO: 104117517
INI: 109177725
SIND: 105167753
LSV: 111918589
DCR: 108218537
BVG: 104906271
SOE: 110794293
NNU: 104607307
OSA: 4333901
DOSA: Os03t0713400-01(Os03g0713400)
OBR: 102715102
BDI: 100844331
ATS: 109734809(LOC109734809)
SBI: 8063381
SITA: 101752822
DCT: 110092482
AOF: 109821727
ATR: 18439560
CRE: CHLREDRAFT_79362(NUOS1)
VCN: VOLCADRAFT_75683(nuoS1)
MNG: MNEG_2352
APRO: F751_1133
PIC: PICST_85822(NUO78)
CAL: CAALFM_CR10140WA(CaO19.7591)
CAUR: QG37_07037
SLB: AWJ20_245
NCR: NCU01765(nuo78)
NTE: NEUTE1DRAFT83867(NEUTE1DRAFT_83867)
MGR: MGG_03155
MAW: MAC_07218
MAJ: MAA_08873
CMT: CCM_04569
MBE: MBM_05615
ANG: ANI_1_908084(An09g06850)
CIM: CIMG_11727(CIMG06326)
PBN: PADG_12148(PADG_06539)
ABE: ARB_06909
TVE: TRV_05932
PTE: PTT_13902
CNE: CNB01310
CNB: CNBB4410
ABP: AGABI1DRAFT41951(NdufS1)
ABV: AGABI2DRAFT194758(NdufS1)
SLA: SERLADRAFT_368495(NdufS1)
MGL: MGL_1856
DDI: DidioMp37
DFA: Difao_mp44(nad11)
PSOJ: PhsooMp31(nad11)
TCR: 509809.10
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1935949
  Authors
Chow W, Ragan I, Robinson BH
  Title
Determination of the cDNA sequence for the human mitochondrial 75-kDa Fe-S protein of NADH-coenzyme Q reductase.
  Journal
Eur J Biochem 201:547-50 (1991)
DOI:10.1111/j.1432-1033.1991.tb16313.x
  Sequence
[hsa:4719]

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