KEGG ORTHOLOGY: K04136

ORTHOLOGY: K04136

Entry

K04136                      KO

Symbol

ADRA1B

Name

adrenergic receptor alpha-1B

Pathway

map04020

Calcium signaling pathway

map04022

cGMP-PKG signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04261

Adrenergic signaling in cardiomyocytes

map04270

Vascular smooth muscle contraction

map04970

Salivary secretion

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04136  ADRA1B; adrenergic receptor alpha-1B
   04022 cGMP-PKG signaling pathway
    K04136  ADRA1B; adrenergic receptor alpha-1B
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04136  ADRA1B; adrenergic receptor alpha-1B
09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04136  ADRA1B; adrenergic receptor alpha-1B
   04270 Vascular smooth muscle contraction
    K04136  ADRA1B; adrenergic receptor alpha-1B
  09154 Digestive system
   04970 Salivary secretion
    K04136  ADRA1B; adrenergic receptor alpha-1B
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04136  ADRA1B; adrenergic receptor alpha-1B
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Biogenic amine
   Adrenaline
    K04136  ADRA1B; adrenergic receptor alpha-1B

Other DBs

GO:

0004937

Genes

HSA:	147(ADRA1B)

PTR:	736934(ADRA1B)

PPS:	106634821(ADRA1B)

GGO:	101142001(ADRA1B)

PON:	100435632(ADRA1B)

NLE:	100601962(ADRA1B)

HMH:	116471787(ADRA1B)

MCC:	695106(ADRA1B)

MCF:	102126794(ADRA1B)

MTHB:

126957210

MNI:	105482341(ADRA1B)

CSAB:

103244899(ADRA1B)

CATY:

105581580(ADRA1B)

PANU:

101026435(ADRA1B)

TGE:	112626945(ADRA1B)

MLEU:

105529547(ADRA1B)

RRO:	104667499(ADRA1B)

RBB:	108537942(ADRA1B)

TFN:	117065532(ADRA1B)

PTEH:

111547133(ADRA1B)

CANG:

105515875(ADRA1B)

CJC:	100395759(ADRA1B)

SBQ:	101040811(ADRA1B)

CIMI:

108285120(ADRA1B)

CSYR:

103259992(ADRA1B)

MMUR:

105883291(ADRA1B)

LCAT:

123638882(ADRA1B)

PCOQ:

105810768(ADRA1B)

OGA:	100961894(ADRA1B)

MMU:	11548(Adra1b)

MCAL:

110305584(Adra1b)

MPAH:

110332008(Adra1b)

RNO:	24173(Adra1b)

MCOC:

116078367(Adra1b)

ANU:	117709867(Adra1b)

MUN:	110555459(Adra1b)

CGE:	103160164(Adra1b)

MAUA:

101843941(Adra1b)

PROB:

127219401(Adra1b)

PLEU:

114689830(Adra1b)

MORG:

121464035(Adra1b)

MFOT:

126499381

AAMP:

119811133(Adra1b)

NGI:	103724547(Adra1b)

HGL:	101700459(Adra1b)

CPOC:

100735480(Adra1b)

CCAN:

109693948(Adra1b)

DORD:

105994962(Adra1b)

DSP:	122125032(Adra1b)

PLOP:

125341903(Adra1b)

NCAR:

124987385

MMMA:

107148066(Adra1b)

OCU:	100008731(ADRA1B)

OPI:	101523367(ADRA1B)

TUP:	102486850(ADRA1B)

GVR:	103602759(ADRA1B)

CFA:	403962(ADRA1B)

CLUD:

112651423(ADRA1B)

VVP:	112928138(ADRA1B)

VLG:	121487856(ADRA1B)

NPO:	129509949(ADRA1B)

AML:	100482658 117801375

UMR:	103664794(ADRA1B)

UAH:	113264037(ADRA1B)

UAR:	123788549(ADRA1B)

ELK:

111141132

LLV:

125100991

MPUF:

101675037(ADRA1B)

MNP:	132028373(ADRA1B)

MLK:	131831852(ADRA1B)

NVS:	122893404(ADRA1B)

ORO:	101371896(ADRA1B)

EJU:	114211957(ADRA1B)

ZCA:	113928399(ADRA1B)

MLX:	118016156(ADRA1B)

NSU:	110587650(ADRA1B)

LWW:	102731415(ADRA1B)

FCA:	101092238(ADRA1B)

PYU:	121010166(ADRA1B)

PCOO:

112860507(ADRA1B)

PBG:	122493023(ADRA1B)

PVIV:

125170081(ADRA1B)

LRUF:

124507100

PTG:	102954633(ADRA1B)

PPAD:

109257572(ADRA1B)

PUC:

125934477

AJU:

106967619

HHV:	120240578(ADRA1B)

BTA:	407140(ADRA1B)

BOM:	102285919(ADRA1B)

BIU:	109562263(ADRA1B)

BBUB:

102390500(ADRA1B)

BBIS:

104999763(ADRA1B)

CHX:	102179850(ADRA1B)

OAS:	101114869(ADRA1B)

BTAX:

128051297(ADRA1B)

ODA:	120863360(ADRA1B)

CCAD:

122439616(ADRA1B)

MBEZ:

129558563(ADRA1B)

SSC:	100519931(ADRA1B)

CFR:	102505346(ADRA1B)

CBAI:

105065254(ADRA1B)

CDK:	105099901(ADRA1B)

VPC:	102530039(ADRA1B)

BACU:

103009751(ADRA1B)

BMUS:

118892688(ADRA1B)

LVE:	103083430(ADRA1B)

OOR:	101273086(ADRA1B)

DLE:	111170633(ADRA1B)

PCAD:

102979753(ADRA1B)

PSIU:

116752300(ADRA1B)

NASI:

112403247(ADRA1B)

ECB:	100071055(ADRA1B)

EPZ:	103553004(ADRA1B)

EAI:	106832140(ADRA1B)

MYB:	102248047(ADRA1B)

MYD:	102772976(ADRA1B)

MMYO:

118659091(ADRA1B)

MLF:	102435324(ADRA1B)

PKL:	118711124(ADRA1B)

EFUS:

103291596(ADRA1B)

MNA:	107537855(ADRA1B)

DRO:	112319490(ADRA1B)

SHON:

118992690(ADRA1B)

AJM:	119054379(ADRA1B)

PDIC:

114509527(ADRA1B)

PHAS:

123811605(ADRA1B)

MMF:	118615824(ADRA1B)

PPAM:

129066506(ADRA1B)

HAI:	109394203(ADRA1B)

RFQ:	117017105(ADRA1B)

PALE:

102891192(ADRA1B)

PGIG:

120614237(ADRA1B)

PVP:	111728760(ADRA1B)

RAY:	107521889(ADRA1B)

MJV:	108403736(ADRA1B)

TOD:	119236252(ADRA1B)

SARA:

101550246(ADRA1B)

SETR:

126011895(ADRA1B)

LAV:	100675999(ADRA1B)

TMU:

101344094

ETF:	101639901(ADRA1B)

DNM:	101439924(ADRA1B)

MDO:	100025515(ADRA1B)

GAS:	123237503(ADRA1B)

SHR:	100933002(ADRA1B)

AFZ:

127550150

PCW:	110212403(ADRA1B)

OAA:	100074819(ADRA1B)

GGA:	373890(ADRA1B)

PCOC:

116232011(ADRA1B)

MGP:	100543635(ADRA1B)

CJO:	107320332(ADRA1B)

TPAI:

128081610(ADRA1B)

LMUT:

125700443(ADRA1B)

NMEL:

110405475(ADRA1B)

APLA:

101800019(ADRA1B)

ACYG:

106034421(ADRA1B)

CATA:

118256751(ADRA1B)

AFUL:

116494894(ADRA1B)

TGU:	100218481(ADRA1B)

LSR:	110476399(ADRA1B)

SCAN:

103817536(ADRA1B)

PMOA:

120498689(ADRA1B)

OTC:	121332359(ADRA1B)

PRUF:

121365581(ADRA1B)

GFR:	102036518(ADRA1B)

FAB:	101814297(ADRA1B)

OMA:	130258797(ADRA1B)

PHI:	102105127(ADRA1B)

PMAJ:

107210901(ADRA1B)

CCAE:

111935785(ADRA1B)

CCW:	104689636(ADRA1B)

CBRC:

103611586(ADRA1B)

ETL:	114066839(ADRA1B)

ZAB:	102070307(ADRA1B)

ACHL:

103809490(ADRA1B)

SVG:	106860448(ADRA1B)

MMEA:

130583408(ADRA1B)

HRT:	120759215(ADRA1B)

FPG:	101920857(ADRA1B)

FCH:	102047141(ADRA1B)

CLV:	102097753(ADRA1B)

EGZ:	104133618(ADRA1B)

NNI:	104016581(ADRA1B)

PCRI:

104031446(ADRA1B)

PLET:

104624806(ADRA1B)

EHS:	104504672(ADRA1B)

PCAO:

104052775

ACUN:

113485191(ADRA1B)

TALA:

104362515(ADRA1B)

PADL:

103912252(ADRA1B)

AFOR:

103904299(ADRA1B)

ACHC:

115334347(ADRA1B)

HALD:

104320250(ADRA1B)

HLE:	104839012(ADRA1B)

AGEN:

126050801

GCL:

127021966

CCRI:

104168949(ADRA1B)

CSTI:

104554201(ADRA1B)

CMAC:

104486719(ADRA1B)

MUI:	104538531(ADRA1B)

BREG:

104640971(ADRA1B)

FGA:	104081010(ADRA1B)

GSTE:

104252589

LDI:	104344749(ADRA1B)

MNB:	103774193(ADRA1B)

OHA:	104330557(ADRA1B)

NNT:	104401001(ADRA1B)

SHAB:

115615974(ADRA1B)

DPUB:

104303954(ADRA1B)

PGUU:

104467649(ADRA1B)

ACAR:

104530739

CPEA:

104392629(ADRA1B)

AVIT:

104272360

CVF:	104281762(ADRA1B)

RTD:	128916252(ADRA1B)

CUCA:

104062909(ADRA1B)

TEO:	104381888(ADRA1B)

BRHI:

104501249(ADRA1B)

AAM:	106493600(ADRA1B)

AROW:

112978169(ADRA1B)

NPD:	112954450(ADRA1B)

TGT:	104577228(ADRA1B)

DNE:	112994299(ADRA1B)

SCAM:

104151044(ADRA1B)

ASN:	102372292(ADRA1B)

CPOO:

109309987(ADRA1B)

GGN:	109290082(ADRA1B)

PSS:	102461525(ADRA1B)

CMY:	102933636(ADRA1B)

CCAY:

125641603(ADRA1B)

DCC:	119860242(ADRA1B)

CPIC:

101947598(ADRA1B)

TST:	117882265(ADRA1B)

CABI:

116833113(ADRA1B)

MRV:	120370611(ADRA1B)

XLA:	108710187(adra1b.L) 108712448(adra1b.S)

XTR:	100488806(adra1b)

NPR:	108788121(ADRA1B)

RTEM:

120932681(ADRA1B)

BBUF:

121007668(ADRA1B)

BGAR:

122926528(ADRA1B)

MUO:	115476849(ADRA1B)

GSH:	117351914(ADRA1B)

DRE:	100149100(adra1ba) 492486(adra1bb)

SRX:	107715309 107730657 107733492 107756509

SANH:

107673805 107684736 107696298

SGH:	107557042 107586059 107590113

CCAR:

109065824 109077550 109098519

CAUA:

113038463 113064055 113091136 113114038

CGIB:

127941529 127971449 127986557 128027494

PTET:

122326122(adra1ba) 122357573(adra1bb)

LROH:

127153000(adra1ba) 127176182(adra1bb)

OMC:	131528994(adra1ba) 131553446(adra1bb)

PPRM:

120460826(adra1bb) 120494458(adra1ba)

RKG:	130075936(adra1bb) 130095324(adra1ba)

MAMB:

125252656(adra1ba) 125259402(adra1bb)

CIDE:

127494234 127504267 127514948

MASI:

127417639 127428421 127431208

TROS:

130563926(adra1bb) 130570518(adra1ba)

TDW:	130408089(adra1ba) 130438086(adra1bb)

MANU:

129421882(adra1bb) 129423225(adra1ba)

IPU:	108269087(adra1bb) 108278461(adra1ba)

IFU:	128612061(adra1bb) 128622819(adra1ba)

PHYP:

113541500(adra1b) 113547160

SMEO:

124386526(adra1bb) 124397731(adra1ba)

TFD:	113644114(adra1ba) 113652943(adra1bb)

TVC:	132855550(adra1bb) 132860436(adra1ba)

AMEX:

103033427(adra1b)

CMAO:

118820672(adra1ba)

EEE:	113568456 113585277(adra1b)

CHAR:

105907396(adra1ba) 105913083

TRU:	101063369 101067265(adra1b)

TFS:	130531629 130538024

TNG:	GSTEN00008099G001 GSTEN00014552G001

LCO:	104922698 104935312

NCC:

104967953

TBEN:

117475191 117490553

CGOB:

115015135 115018963

PGEO:

117444279 117444283 117454472

GACU:

117555955 117556724

EMAC:

134860280 134872123

ELY:	117260654 117270361

EFO:	125894920 125898755

PLEP:

121948040 121963605

SLUC:

116055914 116064454

ECRA:

117951476 117955489

ESP:	116697412(adra1b)

PFLV:

114562944 114566268

GAT:

120817633

PPUG:

119211065 119215823

AFB:	129089887 129113234

CLUM:

PSWI:

MSAM:

SCHU:

CUD:

ALAT:

MZE:	101485219 101485649

ONL:	100692486 106096482(adra1b)

OAU:	116320784 116329170

OLA:	101159125 101159926

OML:	112138073 112152981

CSAI:

133446907 133459252

XMA:	102232317 102237405

XCO:	114139698 114153837

XHE:	116714336 116728928

PRET:

103471229(adra1b) 103476339

PFOR:

103135562(adra1b) 103155418

PLAI:

106934711 106952495(adra1b)

PMEI:

106922321 106928376(adra1b)

GAF:	122837394 122845420

PPRL:

129362475 129370601

CVG:	107098358 107101487(adra1b)

CTUL:

119792427 119794002

GMU:	124859825 124876674

NFU:	107375503(adra1b)

KMR:

108240523

ALIM:

106517703(adra1b)

NWH:

119409024

AOCE:

111573441 111586250

MCEP:

125008422 125021496

CSEM:

103391200(adra1b) 103395768

POV:	109640762 109647108

SSEN:

122778936

HHIP:

117763217 117769415 117774621

HSP:	118112781 118121959

SMAU:

118300234 118319816

LCF:	108873610 108882953 108884074

SDU:	111226616(adra1b) 111239503

SLAL:

111652686 111658584

XGL:	120784973 120802493

HCQ:	109513040 109518810

SSCV:

125982346 125987982

SBIA:

133492259(adra1ba) 133508406

PEE:	133407647 133416366

PTAO:

133467508(adra1ba) 133484893

BPEC:

110157659(adra1b) 110174997

MALB:

109971193(adra1b) 109974220

BSPL:

114864622(adra1bb) 114869456

SJO:	128362944 128371696

SASA:

106567426 106603909 106604929 106611928

STRU:

115148470 115153932 115174707 115205430

OTW:	112220736 112228089 112256062 112258313(adra1ba)

OMY:	100136712 110504794 110533391 110537807(adra1ba)

OGO:	123993228 123995118 123999761 124011642

ONE:	115105214 115125634 115130504 115136149

OKI:	109864813 109873385 109880662 109892185

OKE:	118363353 118370392 118375630 118389768

SALP:

111951002 111965371 111967360 111979943

SNH:	120043913 120048215 120056748 120062553

CCLU:

121574452 121580147 123487346

ELS:	105011294(adra1b) 105029089

SFM:	108934154 108936751(adra1b)

PKI:	111850207 111855193(adra1b)

AANG:

118222330 118236337(adra1ba)

LOC:	102682711(adra1b)

PSPA:

121296831 121324120

ARUT:

117412908 117973754

PSEX:

120542810

LCM:	102367148(ADRA1B)

CMK:

RTP:

CPLA:

HOC:

LERI:

BFO:

BBEL:

SPU:

LPIC:

APLC:

CNS:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

ATD:

OTU:

DCI:

MQU:

BROR:

DPX:	DAPPUDRAFT_66063

DMK:	116916430 116932965 116936310

PJA:	122242972 122248490 122255637

PCHN:

125029544 125034279 125047210

HAME:

121868666 121871754

PCLA:

123751677 123763521

PTRU:

123506501 123510212 123516531

HAZT:

108672663

PPOI:

119097948 119112214 119112350

DSV:

RMP:

VDE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

LPOL:

PMEO:

PVUL:

BGT:

GAE:

HRF:	124116030 124116590

HRJ:	124278528 124286636

CRG:	105334297 105348775

CVN:

111137631

PMAX:

117339219 117339650 117339890

MMER:

123546879 123548032 123562405

RPHI:

DPOL:

OBI:

OSN:

LAK:

ATEN:

116286869 116288910 116289483 116294245 116294263 116295255 116299123 116299361 116300752 116301011 116301122 116301617 116303978 116304974 116306585 116307367 116307850 116308144 116308700

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_59551

» show all

Reference

PMID:7815325

Authors

Schwinn DA, Johnston GI, Page SO, Mosley MJ, Wilson KH, Worman NP, Campbell S, Fidock MD, Furness LM, Parry-Smith DJ, et al.

Title

Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.

Journal

J Pharmacol Exp Ther 272:134-42 (1995)

Sequence

[hsa:147]

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Drug (128)   
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Gene (901)   
   KEGG GENES (606)   
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