KEGG ORTHOLOGY: K04141

ORTHOLOGY: K04141

Entry

K04141 KO

Name

ADRB1

Definition

adrenergic receptor beta-1

Pathway

ko04020	Calcium signaling pathway
ko04080	Neuroactive ligand-receptor interaction
ko04144	Endocytosis
ko04540	Gap junction
ko04970	Salivary secretion
ko05414	Dilated cardiomyopathy

Brite

KEGG Orthology (KO) [BR:ko00001]
Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04141  ADRB1; adrenergic receptor beta-1
Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K04141  ADRB1; adrenergic receptor beta-1
  Cell communication
   04540 Gap junction
    K04141  ADRB1; adrenergic receptor beta-1
Organismal Systems
  Digestive system
   04970 Salivary secretion
    K04141  ADRB1; adrenergic receptor beta-1
Human Diseases
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K04141  ADRB1; adrenergic receptor beta-1
G protein-coupled receptors [BR:ko04030]
Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [Table]
    K04141  ADRB1; adrenergic receptor beta-1

Other DBs

GO:

0004939 0031697

Genes

HSA:	153(ADRB1)
PTR:	466206(ADRB1)
PPS:	100978740(ADRB1)
GGO:	101149664
PON:	100441708(ADRB1)
MMU:	11554(Adrb1)
RNO:	24925(Adrb1)
CFA:	493972(ADRB1)
FCA:	493971(ADRB1)
BTA:	281604(ADRB1)
SSC:	397355(ADRB1)
ECB:	100146832
MDO:	100027410
OAA:	100082919
GGA:	430991(ADRB1)
MGP:	100303680(ADRB1) 100379211(ADRB3)
TGU:	100221186 100221823(ADRB1)
ACS:	100553597 100563228
XLA:	399337(adrb1)
XTR:	100487086
DRE:	100538297 557194(adrb1) 558248(adrb3a) 792519(adrb3b)
TRU:	101063257 101068216
OLA:	101156611 101174028

» show all

Reference

PMID:19912230

Authors

Congreve M, Marshall F

Title

The impact of GPCR structures on pharmacology and structure-based drug design.

Journal

Br J Pharmacol 159:986-96 (2010)

All links

Ontology (8)   
   KEGG BRITE (6)   
   GO (2)   
Pathway (12)   
   KEGG PATHWAY (12)   
Drug (128)   
   KEGG DRUG (128)   
Chemical substance (1)   
   KEGG COMPOUND (1)   
Gene (32)   
   KEGG GENES (31)   
   KEGG DGENES (1)   
Protein sequence (14)   
   UniProt (14)   
Literature (1)   
   PubMed (1)   
All databases (196)   

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