KEGG ORTHOLOGY: K04288

ORTHOLOGY: K04288

Entry

K04288                      KO

Symbol

S1PR1, EDG1, CD363

Name

sphingosine 1-phosphate receptor 1

Pathway

map04068

FoxO signaling pathway

map04071

Sphingolipid signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04148

Efferocytosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K04288  S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
   04071 Sphingolipid signaling pathway
    K04288  S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04288  S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K04288  S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04288  S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
   04090 CD molecules
    K04288  S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Lipid
   Sphingolipid
    K04288  S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
CD molecules [BR:ko04090]
Proteins
  K04288  CD363, S1PR1; sphingosine-1-phosphate receptor 1

Other DBs

GO:

0038036

TC:	9.A.14.2.1

Genes

HSA:	1901(S1PR1)

PTR:	457063(S1PR1)

PPS:	100977957(S1PR1)

GGO:	101127904(S1PR1)

PON:	100174622(S1PR1)

NLE:	100586896(S1PR1)

HMH:	116469701(S1PR1)

MCC:	716813(S1PR1)

MCF:	102127318(S1PR1)

MTHB:

126929132

MNI:	105485479(S1PR1)

CSAB:

103224354(S1PR1)

CATY:

105590129(S1PR1)

PANU:

101013750(S1PR1)

TGE:	112611420(S1PR1)

MLEU:

105548509(S1PR1)

RRO:	104660302(S1PR1)

RBB:	108519966(S1PR1)

TFN:	117074038(S1PR1)

PTEH:

111525753(S1PR1)

CANG:

105506905(S1PR1)

CJC:	100413093(S1PR1)

SBQ:	101041446(S1PR1)

CIMI:

108317260(S1PR1)

CSYR:

103272636(S1PR1)

MMUR:

105862252(S1PR1)

LCAT:

123634959(S1PR1)

PCOQ:

105818798(S1PR1)

OGA:	100958337(S1PR1)

MMU:	13609(S1pr1)

MCAL:

110290910(S1pr1)

MPAH:

110320072(S1pr1)

RNO:	29733(S1pr1)

MCOC:

116093668(S1pr1)

ANU:	117707756(S1pr1)

MUN:	110561456(S1pr1)

CGE:	100689198(S1pr1)

MAUA:

101830449(S1pr1)

PROB:

127223116(S1pr1)

PLEU:

114682445(S1pr1)

MORG:

121452049(S1pr1)

MFOT:

126509237

AAMP:

119801388(S1pr1)

NGI:	103741878(S1pr1)

HGL:	101697978(S1pr1)

CPOC:

100723228(S1pr1)

CCAN:

109698073(S1pr1)

DORD:

105997117(S1pr1)

DSP:	122108779(S1pr1)

PLOP:

125355609(S1pr1)

NCAR:

124964025

MMMA:

107156558(S1pr1)

OCU:	100008820(S1PR1)

OPI:	101533483(S1PR1)

TUP:	102485850(S1PR1)

GVR:	103599457(S1PR1)

CLUD:

112640769(S1PR1)

VVP:	112918220(S1PR1)

VLG:	121487961(S1PR1)

NPO:	129520314(S1PR1)

AML:	100468412(S1PR1)

UMR:	103669319(S1PR1)

UAH:	113254338(S1PR1)

UAR:	123795148(S1PR1)

ELK:

111143048

LLV:

125098672

MPUF:

101681508(S1PR1)

MNP:	132001200(S1PR1)

MLK:	131809568(S1PR1)

NVS:	122900251(S1PR1)

ORO:	101368622(S1PR1)

EJU:	114207965(S1PR1)

ZCA:	113908971(S1PR1)

MLX:	118019075(S1PR1)

NSU:	110580374(S1PR1)

LWW:	102740138(S1PR1)

FCA:	101091218(S1PR1)

PYU:	121027572(S1PR1)

PCOO:

112848971(S1PR1)

PBG:	122480846(S1PR1)

PVIV:

125173909(S1PR1)

LRUF:

124515207

PTG:	102956714(S1PR1)

PPAD:

109271938(S1PR1)

PUC:

125912336

AJU:

106976423

HHV:	120223830(S1PR1)

BTA:	281135(S1PR1)

BOM:	102266604(S1PR1)

BIU:	109556004(S1PR1)

BBUB:

102409030(S1PR1)

BBIS:

104981718(S1PR1)

CHX:	102172679(S1PR1)

OAS:	101115839(S1PR1)

BTAX:

128045006(S1PR1)

ODA:	120856783(S1PR1)

CCAD:

122436626(S1PR1)

MBEZ:

129541236(S1PR1)

SSC:	100621202(S1PR1)

CFR:	102518962(S1PR1)

CBAI:

105065364(S1PR1)

CDK:	105084879(S1PR1)

VPC:	102538188(S1PR1)

BACU:

102999412(S1PR1)

BMUS:

118881811(S1PR1)

LVE:	103090195(S1PR1)

OOR:	101286404(S1PR1)

DLE:	111180107(S1PR1)

PCAD:

102996942(S1PR1)

PSIU:

116763398(S1PR1)

NASI:

112403660(S1PR1)

ECB:	100050049(S1PR1)

EPZ:	103550053(S1PR1)

EAI:	106837769(S1PR1)

MYB:	102248074(S1PR1)

MYD:	102756389(S1PR1)

MMYO:

118673468(S1PR1)

MLF:	102436206(S1PR1)

PKL:	118727199(S1PR1)

EFUS:

103291316(S1PR1)

MNA:	107530666(S1PR1)

DRO:	112313716(S1PR1)

SHON:

118990625(S1PR1)

AJM:	119054984(S1PR1)

PDIC:

114489196(S1PR1)

PHAS:

123804692(S1PR1)

MMF:	118637784(S1PR1)

PPAM:

129063706(S1PR1)

HAI:	109371358(S1PR1)

RFQ:	117015178(S1PR1)

PALE:

102884939(S1PR1)

PGIG:

120607850(S1PR1)

PVP:	105297525(S1PR1)

RAY:	107504393(S1PR1)

MJV:	108402215(S1PR1)

TOD:	119236435(S1PR1)

SARA:

101545960(S1PR1)

SETR:

125997140(S1PR1)

LAV:	100659810(S1PR1)

TMU:

101346522

ETF:	101650504(S1PR1)

DNM:	101416563 101430329(S1PR1)

MDO:	100032972(S1PR1)

GAS:	123243964(S1PR1)

SHR:	100915256(S1PR1)

AFZ:

127559445

PCW:	110217614(S1PR1)

OAA:	100091285(S1PR1)

GGA:	424462(S1PR1)

PCOC:

116243530(S1PR1)

MGP:	100549119(S1PR1)

CJO:	116652400(S1PR1)

TPAI:

128072112(S1PR1)

LMUT:

125693463(S1PR1)

NMEL:

110402395(S1PR1)

APLA:

101798471(S1PR1)

ACYG:

106039474(S1PR1)

CATA:

118243689(S1PR1)

AFUL:

116491864(S1PR1)

TGU:	100224491(S1PR1)

LSR:	110477493(S1PR1)

SCAN:

103814856(S1PR1)

PMOA:

120506484(S1PR1)

OTC:	121345230(S1PR1)

PRUF:

121362104(S1PR1)

GFR:	102036533(S1PR1)

FAB:	101821933(S1PR1)

OMA:	130256328(S1PR1)

PHI:	102113554(S1PR1)

PMAJ:

107208064(S1PR1)

CCAE:

111942847(S1PR1)

CCW:	104695385(S1PR1)

CBRC:

103612568(S1PR1)

ETL:	114061649(S1PR1)

ZAB:	102066416(S1PR1)

ACHL:

103799288

SVG:	106858456(S1PR1)

MMEA:

130572552(S1PR1)

HRT:	131378457(S1PR1)

FPG:	101921626(S1PR1)

FCH:	102050605(S1PR1)

CLV:	102086380(S1PR1)

EGZ:	104134037(S1PR1)

NNI:	104015522(S1PR1)

PCRI:

104037705(S1PR1)

PLET:

104626953(S1PR1)

EHS:	104514847(S1PR1)

PCAO:

104043600(S1PR1)

ACUN:

113483086(S1PR1)

TALA:

104360298(S1PR1)

PADL:

103925091(S1PR1)

AFOR:

103902207(S1PR1)

ACHC:

115349442(S1PR1)

HALD:

104322169(S1PR1)

HLE:	104829410(S1PR1)

AGEN:

126041699

GCL:

127018880

CCRI:

104164782(S1PR1)

CSTI:

104561191(S1PR1)

CMAC:

104482255(S1PR1)

MUI:	104544836(S1PR1)

BREG:

104638788(S1PR1)

FGA:	104073751(S1PR1)

GSTE:

104262270(S1PR1)

LDI:	104353540(S1PR1)

MNB:	103772959(S1PR1)

OHA:	104332568(S1PR1)

NNT:	104409764(S1PR1)

SHAB:

115611938(S1PR1)

DPUB:

104304619(S1PR1)

PGUU:

104461434(S1PR1)

ACAR:

104523562(S1PR1)

CPEA:

104396771(S1PR1)

AVIT:

104278099(S1PR1)

CVF:	104286204(S1PR1)

RTD:	128914218(S1PR1)

CUCA:

104063307(S1PR1)

TEO:	104382346(S1PR1)

BRHI:

104488835(S1PR1)

AAM:	106499742(S1PR1)

AROW:

112966833(S1PR1)

NPD:	112951116(S1PR1)

TGT:	104565820(S1PR1)

DNE:	112979820(S1PR1)

SCAM:

104151236(S1PR1)

ASN:	102387729(S1PR1)

AMJ:	102572888(S1PR1)

CPOO:

109307234(S1PR1)

GGN:	109286891(S1PR1)

PSS:	102461395(S1PR1)

CMY:	102933118(S1PR1)

CCAY:

125641629(S1PR1)

DCC:	119860781(S1PR1)

CPIC:

101942292(S1PR1)

TST:	117881425(S1PR1)

CABI:

116834776(S1PR1)

MRV:	120369831(S1PR1)

ACS:	100557619(s1pr1)

ASAO:

132774186(S1PR1)

PVT:	110076502(S1PR1)

SUND:

121929330(S1PR1)

PBI:	103048499(S1PR1)

PMUR:

107302502(S1PR1)

CTIG:

120310252(S1PR1)

TSR:	106544093(S1PR1)

PGUT:

117677268(S1PR1)

APRI:

131196220(S1PR1)

PTEX:

113436158(S1PR1)

NSS:	113414759(S1PR1)

VKO:	123024594(S1PR1)

PMUA:

114598698(S1PR1)

PRAF:

128415424(S1PR1)

ZVI:	118089032(S1PR1)

HCG:	128324770(S1PR1)

GJA:	107125954(S1PR1)

STOW:

125433019(S1PR1)

EMC:	129329962(S1PR1)

XLA:	108715691(s1pr1.S) 444659(s1pr1.L)

XTR:	780355(s1pr1)

NPR:	108791467(S1PR1)

RTEM:

120945615(S1PR1)

BBUF:

120979468(S1PR1)

BGAR:

122943557(S1PR1)

MUO:	115472945(S1PR1)

GSH:	117346841(S1PR1)

DRE:	64617(s1pr1)

SRX:	107715096 107735137 107757487(s1pr1)

SANH:

107653630 107669844

SGH:	107588065 107592715

CCAR:

109047783 109047784

CAUA:

113040134 113064847

CGIB:

127943204 127988341

PTET:

122328067(s1pr1)

LROH:

127153945(s1pr1)

OMC:	131531201(s1pr1)

PPRM:

120486778(s1pr1)

RKG:	130089300(s1pr1)

MAMB:

125251269(s1pr1)

CIDE:

127521464

MASI:

127438599 127438629

TROS:

130549023(s1pr1)

TDW:	130430794(s1pr1)

MANU:

129453192(s1pr1)

IPU:

108271403

IFU:	128614032(s1pr1)

PHYP:

113536708(s1pr1)

SMEO:

124391155(s1pr1)

TFD:	113650713(s1pr1)

TVC:	132854482(s1pr1)

AMEX:

103038116(s1pr1)

CMAO:

118819371(s1pr1)

EEE:	113574466(s1pr1)

CHAR:

105912941(s1pr1)

TRU:	101066081(s1pr1)

TFS:	130528977(s1pr1)

TNG:	GSTEN00004794G001

LCO:	104939430(s1pr1)

NCC:	104943215(s1pr1)

TBEN:

117497829(s1pr1)

PGEO:

117444225(s1pr1)

GACU:

117560351(s1pr1)

EMAC:

134869062(s1pr1)

ELY:	117253562(s1pr1)

EFO:	125896307(s1pr1)

PLEP:

121940478(s1pr1)

SLUC:

116059031(s1pr1)

ECRA:

117951003(s1pr1)

PFLV:

114561518(s1pr1)

GAT:	120824186(s1pr1)

PPUG:

119217083(s1pr1)

AFB:	129094121(s1pr1)

CLUM:

117729727(s1pr1)

PSWI:

130193894(s1pr1)

MSAM:

119889328

SCHU:

122877741(s1pr1)

CUD:	121512383(s1pr1)

ALAT:

119028916(s1pr1)

MZE:	101481422(s1pr1)

ONL:	100692178(s1pr1)

OAU:	116320846(s1pr1)

OLA:	101171482(s1pr1)

OML:	112136743(s1pr1)

CSAI:

133458691(s1pr1)

XMA:	102227968(s1pr1)

XCO:	114141466(s1pr1)

XHE:	116725894(s1pr1)

PRET:

103463159(s1pr1)

PFOR:

103150017(s1pr1)

PLAI:

106954344(s1pr1)

PMEI:

106922600(s1pr1)

GAF:	122838558(s1pr1)

PPRL:

129378280(s1pr1)

CVG:	107094693(s1pr1)

CTUL:

119784598(s1pr1)

GMU:	124874459(s1pr1)

NFU:	107393085(s1pr1)

KMR:	108248667(s1pr1)

ALIM:

106525065(s1pr1)

NWH:	119407615(s1pr1)

AOCE:

111583776(s1pr1)

MCEP:

125009807(s1pr1)

CSEM:

103398542(s1pr1)

POV:	109646393(s1pr1)

SSEN:

122780658(s1pr1)

HHIP:

117759844(s1pr1)

HSP:	118120985(s1pr1)

SMAU:

118318795(s1pr1)

LCF:

108874189

SDU:	111236214(s1pr1)

SLAL:

111668245(s1pr1)

XGL:	120790930(s1pr1)

HCQ:	109506814(s1pr1)

SSCV:

125975551

SBIA:

133503494(s1pr1)

PEE:	133406283(s1pr1)

PTAO:

133480842(s1pr1)

BPEC:

110172384(s1pr1)

MALB:

109965293(s1pr1)

BSPL:

114853147(s1pr1)

SJO:	128361643(s1pr1)

SASA:

106573949 106613588

STRU:

115151622 115158060

OTW:	112251541 112252084(s1pr1)

OMY:	110488417 110524100

OGO:	123991332(s1pr1) 123996579

ONE:

115108139

OKI:	109887980 109902341

OKE:	118387732 118401504

SALP:

111952900 111975789

SNH:	120053706 120054658

CCLU:

121533699 121576461

ELS:	105011380(s1pr1)

SFM:	108919011(s1pr1) 108935093

PKI:	111844589(s1pr1)

AANG:

118224599(s1pr1) 118228899

LOC:	102683081(s1pr1) 102689955

PSPA:

121294094 121327024

ARUT:

117403263 117417300

PSEX:

120537982(s1pr1)

LCM:	102345178 102346859(S1PR1)

CMK:	103188847(s1pr1)

RTP:	109911482(s1pr1)

CPLA:

122554517(s1pr1)

HOC:	132819007(s1pr1)

LERI:

129701232(s1pr1)

PMRN:

116938891 116948811(S1PR1) 116951873

LRJ:	133346558 133350681 133351836(S1PR1)

BFO:	118403389 118406882 118408465 118409078 118413367 118417651 118421205 118422693 118424406 118430512

BBEL:

109463067 109464506 109464756 109467333 109472536 109475456 109477926 109478137 109485902 109486441 109487037 109488058

SCLV:

120327779 120329474

OED:	125656211 130053675

MMER:

123546717

OSN:

115231397

EGL:

EGR_07875

NVE:	116614026 5506498 5510020 5514499 5522135

EPA:	110237065 110242507

ADF:	107330138 107349295

AMIL:

114962071

SPIS:

111326845 111327603 111331962 111334760 111337567 111337863

DGT:

XEN:

HSY:

Reference

PMID:10982820

Authors

Parrill AL, Wang D, Bautista DL, Van Brocklyn JR, Lorincz Z, Fischer DJ, Baker DL, Liliom K, Spiegel S, Tigyi G

Title

Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate.

Journal

J Biol Chem 275:39379-84 (2000)
DOI:10.1074/jbc.M007680200

Sequence

[hsa:1901]

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Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   TC (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Drug (17)   
   KEGG DRUG (17)   
Gene (914)   
   KEGG GENES (465)   
   KEGG MGENES (161)   
   RefGene (278)   
   OC (10)   
Literature (1)   
   PubMed (1)   
All databases (945)   

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