KEGG ORTHOLOGY: K04369

ORTHOLOGY: K04369

Entry

K04369                      KO

Symbol

MAP2K2, MEK2

Name

mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]

Pathway

map01521

EGFR tyrosine kinase inhibitor resistance

map01522

Endocrine resistance

map04010

MAPK signaling pathway

map04012

ErbB signaling pathway

map04014

Ras signaling pathway

map04015

Rap1 signaling pathway

map04022

cGMP-PKG signaling pathway

map04024

cAMP signaling pathway

map04066

HIF-1 signaling pathway

map04068

FoxO signaling pathway

map04071

Sphingolipid signaling pathway

map04072

Phospholipase D signaling pathway

map04140

Autophagy - animal

map04148

Efferocytosis

map04150

mTOR signaling pathway

map04151

PI3K-Akt signaling pathway

map04210

Apoptosis

map04218

Cellular senescence

map04270

Vascular smooth muscle contraction

map04370

VEGF signaling pathway

map04371

Apelin signaling pathway

map04540

Gap junction

map04550

Signaling pathways regulating pluripotency of stem cells

map04613

Neutrophil extracellular trap formation

map04620

Toll-like receptor signaling pathway

map04650

Natural killer cell mediated cytotoxicity

map04660

T cell receptor signaling pathway

map04662

B cell receptor signaling pathway

map04664

Fc epsilon RI signaling pathway

map04720

Long-term potentiation

map04722

Neurotrophin signaling pathway

map04730

Long-term depression

map04810

Regulation of actin cytoskeleton

map04910

Insulin signaling pathway

map04912

GnRH signaling pathway

map04915

Estrogen signaling pathway

map04916

Melanogenesis

map04917

Prolactin signaling pathway

map04919

Thyroid hormone signaling pathway

map04921

Oxytocin signaling pathway

map04926

Relaxin signaling pathway

map04929

GnRH secretion

map04934

Cushing syndrome

map04935

Growth hormone synthesis, secretion and action

map05010

Alzheimer disease

map05022

Pathways of neurodegeneration - multiple diseases

map05132

Salmonella infection

map05135

Yersinia infection

map05160

Hepatitis C

map05161

Hepatitis B

map05163

Human cytomegalovirus infection

map05164

Influenza A

map05165

Human papillomavirus infection

map05166

Human T-cell leukemia virus 1 infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05170

Human immunodeficiency virus 1 infection

map05200

Pathways in cancer

map05205

Proteoglycans in cancer

map05206

MicroRNAs in cancer

map05207

Chemical carcinogenesis - receptor activation

map05208

Chemical carcinogenesis - reactive oxygen species

map05210

Colorectal cancer

map05211

Renal cell carcinoma

map05213

Endometrial cancer

map05214

Glioma

map05215

Prostate cancer

map05216

Thyroid cancer

map05218

Melanoma

map05219

Bladder cancer

map05220

Chronic myeloid leukemia

map05221

Acute myeloid leukemia

map05223

Non-small cell lung cancer

map05224

Breast cancer

map05225

Hepatocellular carcinoma

map05226

Gastric cancer

map05230

Central carbon metabolism in cancer

map05231

Choline metabolism in cancer

map05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

Disease

H00523

Noonan syndrome and related disorders

H01745

Cardiofaciocutaneous syndrome

H02425

Erdheim-Chester disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04012 ErbB signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04014 Ras signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04015 Rap1 signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04370 VEGF signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04371 Apelin signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04066 HIF-1 signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04068 FoxO signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04072 Phospholipase D signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04071 Sphingolipid signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04024 cAMP signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04022 cGMP-PKG signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04151 PI3K-Akt signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04150 mTOR signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04148 Efferocytosis
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09143 Cell growth and death
   04210 Apoptosis
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04218 Cellular senescence
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04550 Signaling pathways regulating pluripotency of stem cells
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04620 Toll-like receptor signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04650 Natural killer cell mediated cytotoxicity
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04660 T cell receptor signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04662 B cell receptor signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04664 Fc epsilon RI signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09152 Endocrine system
   04910 Insulin signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04929 GnRH secretion
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04912 GnRH signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04915 Estrogen signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04917 Prolactin signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04921 Oxytocin signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04926 Relaxin signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04935 Growth hormone synthesis, secretion and action
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04919 Thyroid hormone signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04916 Melanogenesis
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09156 Nervous system
   04720 Long-term potentiation
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04730 Long-term depression
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   04722 Neurotrophin signaling pathway
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05206 MicroRNAs in cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05205 Proteoglycans in cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05207 Chemical carcinogenesis - receptor activation
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05208 Chemical carcinogenesis - reactive oxygen species
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05230 Central carbon metabolism in cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05231 Choline metabolism in cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05225 Hepatocellular carcinoma
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05226 Gastric cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05214 Glioma
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05216 Thyroid cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05221 Acute myeloid leukemia
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05220 Chronic myeloid leukemia
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05218 Melanoma
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05211 Renal cell carcinoma
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05219 Bladder cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05215 Prostate cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05213 Endometrial cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05224 Breast cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05223 Non-small cell lung cancer
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05170 Human immunodeficiency virus 1 infection
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05161 Hepatitis B
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05160 Hepatitis C
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05164 Influenza A
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05163 Human cytomegalovirus infection
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05165 Human papillomavirus infection
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05135 Yersinia infection
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   05022 Pathways of neurodegeneration - multiple diseases
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
   01522 Endocrine resistance
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2
Protein kinases [BR:ko01001]
Serine/threonine kinases: STE group
  STE7 family
   K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2

Other DBs

GO:

0004708

Genes

HSA:	5605(MAP2K2)

PTR:	456390(MAP2K2)

PPS:	100977025 100988437

GGO:

101126885

PON:	100450988(MAP2K2)

NLE:	100591827(MAP2K2)

HMH:	116483548(MAP2K2) 116814342

MCC:	721821(MAP2K2)

MCF:

102140855

MTHB:

126942673

MNI:	105485357(MAP2K2)

CSAB:

103233717(MAP2K2)

CATY:

105591800(MAP2K2)

PANU:

101004074(MAP2K2)

TGE:	112612394(MAP2K2)

MLEU:

105530027(MAP2K2)

RRO:	104665487(MAP2K2)

RBB:	108512087(MAP2K2)

TFN:	117076490(MAP2K2)

PTEH:

111521954(MAP2K2)

CANG:

105512832(MAP2K2)

CJC:	100393991(MAP2K2)

SBQ:	101036151(MAP2K2)

CIMI:

108288453(MAP2K2)

CSYR:

103251709

MMUR:

105873938(MAP2K2)

LCAT:

123633879(MAP2K2)

PCOQ:

105811965(MAP2K2)

OGA:	100956072(MAP2K2)

MMU:	26396(Map2k2)

MCAL:

110303196(Map2k2)

MPAH:

110326321(Map2k2)

RNO:	58960(Map2k2)

MCOC:

116076013(Map2k2)

ANU:	117696143(Map2k2)

MUN:	110555605(Map2k2)

CGE:	100774204(Map2k2)

MAUA:

101822879(Map2k2)

PROB:

127216563(Map2k2)

PLEU:

114688121(Map2k2)

MORG:

121459389(Map2k2)

MFOT:

126489299

AAMP:

119827491(Map2k2)

NGI:	103737276(Map2k2)

HGL:	101707562(Map2k2)

CPOC:

100728923(Map2k2)

CCAN:

109687808(Map2k2)

DORD:

105990471(Map2k2)

DSP:	122099331(Map2k2)

PLOP:

125348606(Map2k2)

NCAR:

124969568

MMMA:

107157283(Map2k2)

OPI:	101529486(MAP2K2) 105942099

TUP:	102483700(MAP2K2)

GVR:	103600170(MAP2K2)

CFA:	611939(MAP2K2)

CLUD:

112666294(MAP2K2)

VVP:	112935545(MAP2K2)

VLG:	121495470(MAP2K2)

NPO:	129522322(MAP2K2)

AML:	100465700(MAP2K2)

UMR:	103681834(MAP2K2)

UAH:	113242822(MAP2K2)

UAR:	123796818(MAP2K2)

ELK:

111161815

LLV:

125086704

MPUF:

101678743(MAP2K2)

MNP:	132010799(MAP2K2)

MLK:	131823312(MAP2K2)

NVS:	122909871(MAP2K2)

ORO:	101376586(MAP2K2)

EJU:	114226331(MAP2K2)

ZCA:	113917006(MAP2K2)

MLX:	118004882(MAP2K2)

NSU:	110593734(MAP2K2)

LWW:	102745982(MAP2K2)

FCA:	101100281(MAP2K2)

PYU:	121021465(MAP2K2)

PCOO:

112852828(MAP2K2)

PBG:	122486708(MAP2K2)

PVIV:

125149335(MAP2K2)

LRUF:

124524782

PTG:	102956808(MAP2K2)

PPAD:

109255967(MAP2K2)

PUC:	125918032 125918034

AJU:

106975474

HHV:	120242086(MAP2K2)

BTA:	510434(MAP2K2)

BOM:	102271710(MAP2K2)

BIU:	109561751(MAP2K2)

BBUB:

102401744(MAP2K2)

BBIS:

104979900(MAP2K2)

CHX:	102175285(MAP2K2)

OAS:	101113846(MAP2K2)

BTAX:

128050664(MAP2K2)

ODA:	120864821(MAP2K2)

CCAD:

122440231 122440910 122446062

MBEZ:

129558523(MAP2K2)

SSC:	100525505(MAP2K2)

CFR:	102511209(MAP2K2)

CBAI:

105078209(MAP2K2)

CDK:	105105302(MAP2K2)

VPC:	102534668(MAP2K2)

BACU:

103018627(MAP2K2)

BMUS:

118892655(MAP2K2)

LVE:	103090769(MAP2K2)

OOR:	101287162(MAP2K2)

DLE:	111165994(MAP2K2)

PCAD:

102994150(MAP2K2)

PSIU:

116751189(MAP2K2)

NASI:

112400165(MAP2K2)

ECB:	100063190(MAP2K2)

EPZ:

103543290

EAI:	106832322(MAP2K2)

MYB:	102245571(MAP2K2)

MYD:	102757282(MAP2K2)

MMYO:

118657986(MAP2K2)

MLF:	102423748(MAP2K2)

PKL:	118731359(MAP2K2)

EFUS:

103294231(MAP2K2)

MNA:	107525695(MAP2K2)

DRO:	112312483(MAP2K2)

SHON:

118984505(MAP2K2)

AJM:	119063754(MAP2K2)

PDIC:

114503388(MAP2K2)

PHAS:

123813640(MAP2K2)

MMF:	118615385(MAP2K2)

PPAM:

129078155(MAP2K2)

HAI:	109388626(MAP2K2)

RFQ:	117037633(MAP2K2)

PALE:

102879034(MAP2K2)

PGIG:

120615382(MAP2K2)

PVP:	105306744(MAP2K2)

RAY:	107510634(MAP2K2)

MJV:	108385046(MAP2K2)

TOD:	119240577(MAP2K2)

SARA:

101555057(MAP2K2)

SETR:

126029670(MAP2K2)

LAV:	100657587(MAP2K2)

TMU:

101341078

ETF:	101643986(MAP2K2)

DNM:

101420546

MDO:	100018044(MAP2K2)

GAS:	123243007(MAP2K2)

SHR:	100917396(MAP2K2)

AFZ:

127544950

PCW:	110197417(MAP2K2)

OAA:	100087942(MAP2K2)

GGA:	396349(MAP2K2)

PCOC:

116235833(MAP2K2)

MGP:	100551337(MAP2K2)

CJO:	107325595(MAP2K2)

TPAI:

128090447(MAP2K2)

LMUT:

125684996(MAP2K2)

NMEL:

110388854(MAP2K2)

APLA:

119714201(MAP2K2)

ACYG:

106044951(MAP2K2)

CATA:

118258785(MAP2K2)

AFUL:

116499043(MAP2K2)

TGU:	100225195(MAP2K2)

LSR:	110478470(MAP2K2)

SCAN:

103824555(MAP2K2)

PMOA:

120499033(MAP2K2)

OTC:	121346775(MAP2K2)

PRUF:

121349910(MAP2K2)

GFR:	102041148(MAP2K2)

FAB:	101820507(MAP2K2)

OMA:	130264419(MAP2K2)

PHI:	102102285(MAP2K2)

PMAJ:

107215477(MAP2K2)

CCAE:

111940193(MAP2K2)

CCW:	104697410(MAP2K2)

CBRC:

103621207(MAP2K2)

ETL:	114068839(MAP2K2)

ZAB:	102064782(MAP2K2)

SVG:	106859747(MAP2K2)

MMEA:

130586756(MAP2K2)

HRT:	120763546(MAP2K2)

FPG:	101924296(MAP2K2)

FCH:	102049695(MAP2K2)

CLV:	102097053(MAP2K2)

EGZ:	104124397(MAP2K2)

NNI:	104018809(MAP2K2)

PCRI:

104024608(MAP2K2)

PLET:

104625875(MAP2K2)

EHS:

104509254

PCAO:

104050091(MAP2K2)

ACUN:

113489457(MAP2K2)

TALA:

104361599(MAP2K2)

PADL:

103916484(MAP2K2)

AFOR:

103900480(MAP2K2)

ACHC:

115349300(MAP2K2)

HALD:

104318307(MAP2K2)

HLE:	104828537(MAP2K2)

AGEN:

126041897

GCL:

127025478

CCRI:

104154633(MAP2K2)

CSTI:

104554578(MAP2K2)

CMAC:

104480033(MAP2K2)

MUI:	104540075(MAP2K2)

BREG:

104629471

FGA:	104074202(MAP2K2)

GSTE:

104257187(MAP2K2)

LDI:	104349592(MAP2K2)

MNB:	103769043(MAP2K2)

OHA:	104330857(MAP2K2)

NNT:	104404578(MAP2K2)

SHAB:

115618167(MAP2K2)

DPUB:

104303243(MAP2K2)

PGUU:

104468104

ACAR:

104518296(MAP2K2)

CPEA:

104391569

AVIT:

104281173(MAP2K2)

CVF:	104282773(MAP2K2)

RTD:	128900734(MAP2K2)

CUCA:

104056230(MAP2K2)

TEO:

104376146

BRHI:

104494663(MAP2K2)

AAM:	106492199(MAP2K2)

AROW:

112972305(MAP2K2)

NPD:	112949088(MAP2K2)

TGT:	104576452(MAP2K2)

DNE:	112994722(MAP2K2)

SCAM:

104145759(MAP2K2)

ASN:	102375508(MAP2K2)

AMJ:	106736997(MAP2K2)

CPOO:

109324852(MAP2K2)

GGN:	109294689(MAP2K2)

PSS:	102457075(MAP2K2)

CMY:	102931357(MAP2K2)

CCAY:

125627064(MAP2K2)

DCC:	119848307(MAP2K2)

CPIC:

101938330(MAP2K2)

TST:	117868754(MAP2K2)

CABI:

116819019(MAP2K2)

MRV:	120391732(MAP2K2)

ACS:	100567176(map2k2)

ASAO:

132781741(MAP2K2)

PVT:	110072466(MAP2K2)

SUND:

121921221 121936502(MAP2K2)

PBI:	103067786(MAP2K2)

PMUR:

107295320(MAP2K2)

CTIG:

120305410(MAP2K2)

TSR:	106555305(MAP2K2)

PGUT:

117656242(MAP2K2)

APRI:

131188390(MAP2K2)

PTEX:

113450336(MAP2K2)

NSS:	113425513(MAP2K2)

VKO:	123017589(MAP2K2)

PMUA:

114588247(MAP2K2)

PRAF:

128405737(MAP2K2)

ZVI:	118086608(MAP2K2)

HCG:	128346136(MAP2K2)

GJA:	107118240(MAP2K2)

STOW:

125432678(MAP2K2)

EMC:	129330130(MAP2K2)

BBUF:

120989541(MAP2K2)

BGAR:

122929119(MAP2K2)

MUO:	115480590(MAP2K2)

GSH:	117365220(MAP2K2)

DRE:	100002225(map2k2b) 563181(map2k2a)

SRX:	107719582 107724975 107726325 107729695

SANH:

107655207 107671813 107676947 107676988 107696522

SGH:	107552672 107575785 107586388 107596877

CCAR:

109046734 109046735 109100030

CAUA:

113039644 113045154 113045216 113064928

CGIB:

127942667 127986868

PTET:

122324621(map2k2b) 122327733(map2k2a)

LROH:

127153291(map2k2b) 127153476(map2k2a)

OMC:	131530277(map2k2a) 131552281(map2k2b)

PPRM:

120471345(map2k2b) 120495436(map2k2a)

RKG:	130089196(map2k2a)

MAMB:

125250873(map2k2b) 125263787(map2k2a)

CIDE:

127502256 127519987

MASI:

127438106 127439045 127441351

TROS:

130549161(map2k2a) 130553870(map2k2b)

TDW:	130418373(map2k2b) 130430266(map2k2a)

MANU:

129443289(map2k2b) 129453519(map2k2a)

IPU:	100528123(map2k2b) 108271291(map2k2a)

IFU:	128613746(map2k2a) 128624239(map2k2b)

PHYP:

113530702 113533517

SMEO:

124391383(map2k2a) 124403350(map2k2b)

TFD:	113645293(map2k2b) 113657741(map2k2a)

TVC:	132845593(map2k2b) 132853123(map2k2a)

AMEX:

103030512(map2k2)

CMAO:

118797185(map2k2b) 118818647(map2k2a)

EEE:	113584672 113588939

CHAR:

105905870 116219516 122132003

TRU:	101070236(map2k2)

TFS:	130528688(map2k2a)

TNG:	GSTEN00004843G001

LCO:	104920827(map2k2) 104929670

NCC:	104963431(map2k2) 104965132

TBEN:

117488653(map2k2b) 117495666(map2k2a)

CGOB:

115007241(map2k2) 115022522

PGEO:

117445380(map2k2a) 117462440(map2k2b)

GACU:

117532733(map2k2b) 117546153(map2k2a)

EMAC:

134866187(map2k2b) 134869745(map2k2a)

ELY:	117254181(map2k2a) 117271479(map2k2b)

EFO:	125895747(map2k2a) 125902384(map2k2b)

PLEP:

121938842(map2k2a) 121951784(map2k2b)

SLUC:

116037337(map2k2b) 116063461(map2k2a)

ECRA:

117950204(map2k2a) 117954500(map2k2b)

ESP:	116695172(map2k2) 116699426 116699428

PFLV:

114561797 114565370

GAT:	120816299(map2k2b) 120823910(map2k2a)

PPUG:

119209642(map2k2b) 119216703(map2k2a)

AFB:	129094155(map2k2a) 129112227(map2k2b)

CLUM:

117729985(map2k2a) 117746647(map2k2b)

PSWI:

130194253(map2k2a)

MSAM:

119900881(map2k2a) 119902918(map2k2b)

SCHU:

122877476(map2k2a) 122886281(map2k2b)

CUD:	121512343(map2k2a) 121520316(map2k2b)

ALAT:

119011484(map2k2b) 119028360(map2k2a)

MZE:	101478402 101484555

ONL:	100697571 100708547

OAU:	116310020(map2k2a) 116319019(map2k2b)

OLA:	101173453(map2k2)

OML:	112136869(map2k2a)

CSAI:

133458123(map2k2a)

XMA:	102225775(map2k2)

XCO:	114151477(map2k2)

XHE:	116726343(map2k2)

PRET:

103463649(map2k2)

PFOR:

103149822(map2k2)

PLAI:

106959224(map2k2)

PMEI:

106915816(map2k2)

GAF:	122839029(map2k2a)

PPRL:

129376705(map2k2a)

CVG:	107089725(map2k2)

CTUL:

119792552(map2k2a)

GMU:	124874089(map2k2a)

NFU:	107393294(map2k2)

KMR:	108230840(map2k2a)

ALIM:

106515024(map2k2)

NWH:	119407953(map2k2a)

AOCE:

111568133(map2k2) 111572311

MCEP:

125009454(map2k2a) 125010654(map2k2b)

CSEM:

103376625(map2k2)

POV:

109625750

SSEN:

122781086(map2k2a)

HHIP:

117759678(map2k2a)

HSP:	124854736(map2k2a)

SMAU:

118311178(map2k2b) 118318813(map2k2a)

LCF:	108877315(map2k2a) 108883596(map2k2b)

SDU:	111229041 111232170

SLAL:

111652614 111656372(map2k2)

XGL:	120791009(map2k2a) 120798627(map2k2b)

HCQ:

109532301

SSCV:

125965738

SBIA:

133503693(map2k2a)

PEE:	133406476(map2k2a)

PTAO:

133481008(map2k2a)

BPEC:

110173999(map2k2)

MALB:

109967020 109974179

BSPL:

114845208(map2k2b) 114853520(map2k2a)

SJO:	128361721(map2k2a)

SASA:

100194780(mp2k2) 106569535 106600441 106613775

STRU:

115157409 115158253 115169411 115192626

OTW:	112231367 112237794(map2k2b) 112250875(map2k2a)

OMY:	100136127(tmek) 110508416 110524297 110530696(map2k2b)

OGO:	123997082(map2k2a) 124009586(map2k2b) 124037664

ONE:	115108309 115114736 115144888

OKI:	109872320 109874662 109897850 109902503

OKE:	118359232 118389751 118401816(map2k2b)

SALP:

111956577 111972098 111975763 111978999

SNH:	120020580 120052438 120054777 120056021(map2k2b)

CCLU:

121533527 121535511(map2k2b) 121540361(map2k2a) 121581348

ELS:	105011557 105020581

SFM:	108919814 108921692(map2k2)

PKI:	111836645(map2k2) 111860367

AANG:

118226171(map2k2a) 118230058(map2k2b)

LOC:	102686784(map2k2)

PSPA:

121300828(map2k2a) 121301294

ARUT:

117401470 117966151

PSEX:

120537759(map2k2a)

LCM:	102350370(MAP2K2)

CMK:

103183530

CPLA:

122565176

HOC:	132829027(map2k2a)

LERI:

129711246

PMRN:

116939688(MAP2K1)

LRJ:	133346627(MAP2K1)

LPIC:

129261697

RSAN:

119385920

EPA:	110245894 110250375

ATEN:

XEN:

HMG:

Reference

PMID:8297798

Authors

Brott BK, Alessandrini A, Largaespada DA, Copeland NG, Jenkins NA, Crews CM, Erikson RL

Title

MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues.

Journal

Cell Growth Differ 4:921-9 (1993)

Sequence

[mmu:26396]

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