KEGG   ORTHOLOGY: K04377Help
Entry
K04377                      KO                                     

Name
MYC
Definition
Myc proto-oncogene protein
Pathway
MAPK signaling pathway
ErbB signaling pathway
Cell cycle
PI3K-Akt signaling pathway
Wnt signaling pathway
TGF-beta signaling pathway
Hippo signaling pathway
Hippo signaling pathway - fly
Signaling pathways regulating pluripotency of stem cells
Jak-STAT signaling pathway
Thyroid hormone signaling pathway
Hepatitis B
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Transcriptional misregulation in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Colorectal cancer
Endometrial cancer
Thyroid cancer
Bladder cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Central carbon metabolism in cancer
Disease
H00001  
Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
H00002  
Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
H00008  
Burkitt lymphoma
H00010  
Multiple myeloma
H00013  
Small cell lung cancer
H00016  
Oral cancer
H00025  
Penile cancer
H00027  
Ovarian cancer
H00028  
Choriocarcinoma
H00031  
Breast cancer
H00036  
Osteosarcoma
H00041  
Kaposi's sarcoma
H00055  
Laryngeal cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04012 ErbB signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04310 Wnt signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04350 TGF-beta signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04390 Hippo signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04391 Hippo signaling pathway -fly
    K04377  MYC; Myc proto-oncogene protein
   04630 Jak-STAT signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04151 PI3K-Akt signaling pathway
    K04377  MYC; Myc proto-oncogene protein
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K04377  MYC; Myc proto-oncogene protein
  Cellular commiunity
   04550 Signaling pathways regulating pluripotency of stem cells
    K04377  MYC; Myc proto-oncogene protein
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    K04377  MYC; Myc proto-oncogene protein
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04377  MYC; Myc proto-oncogene protein
   05230 Central carbon metabolism in cancer
    K04377  MYC; Myc proto-oncogene protein
   05202 Transcriptional misregulation in cancers
    K04377  MYC; Myc proto-oncogene protein
   05206 MicroRNAs in cancer
    K04377  MYC; Myc proto-oncogene protein
   05205 Proteoglycans in cancer
    K04377  MYC; Myc proto-oncogene protein
   05210 Colorectal cancer
    K04377  MYC; Myc proto-oncogene protein
   05216 Thyroid cancer
    K04377  MYC; Myc proto-oncogene protein
   05221 Acute myeloid leukemia
    K04377  MYC; Myc proto-oncogene protein
   05220 Chronic myeloid leukemia
    K04377  MYC; Myc proto-oncogene protein
   05219 Bladder cancer
    K04377  MYC; Myc proto-oncogene protein
   05213 Endometrial cancer
    K04377  MYC; Myc proto-oncogene protein
   05222 Small cell lung cancer
    K04377  MYC; Myc proto-oncogene protein
  Infectious diseases
   05166 HTLV-I infection
    K04377  MYC; Myc proto-oncogene protein
   05161 Hepatitis B
    K04377  MYC; Myc proto-oncogene protein
   05169 Epstein-Barr virus infection
    K04377  MYC; Myc proto-oncogene protein
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
   Cell cycle controlling factors, Myc
    K04377  MYC; Myc proto-oncogene protein
BRITE hierarchy
Genes
HSA: 
4609(MYC)
PTR: 
464393(MYC)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
694626(MYC)
MCF: 
CJC: 
MMU: 
17869(Myc)
RNO: 
24577(Myc)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
403924(MYC)
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
511077(MYC)
BOM: 
PHD: 
CHX: 
OAS: 
443447(MYC)
SSC: 
448810(MYC)
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
420332(MYC)
MGP: 
APLA: 
TGU: 
FAB: 
PHI: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
379052(myc-a) 399315(myc)
XTR: 
DRE: 
393141(mycb)
TRU: 
653028(c-myc)
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
CQU: 
NVI: 
BMOR: 
PHU: 
ISC: 
NVE: 
HMG: 
100199110(myc2)
TAD: 
AQU: 
MBR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Albihn A, Johnsen JI, Henriksson MA
  Title
MYC in oncogenesis and as a target for cancer therapies.
  Journal
Adv Cancer Res 107:163-224 (2010)
Reference
  Authors
Bellosta P, Hulf T, Balla Diop S, Usseglio F, Pradel J, Aragnol D, Gallant P
  Title
Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.
  Journal
Proc Natl Acad Sci U S A 102:11799-804 (2005)
  Sequence

DBGET integrated database retrieval system