KEGG   ORTHOLOGY: K04389Help
Entry
K04389                      KO                                     

Name
TNFSF6, FASL
Definition
tumor necrosis factor ligand superfamily member 6
Pathway
MAPK signaling pathway
Ras signaling pathway
Cytokine-cytokine receptor interaction
FoxO signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Natural killer cell mediated cytotoxicity
Neurotrophin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Type I diabetes mellitus
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Pathways in cancer
Proteoglycans in cancer
Autoimmune thyroid disease
Allograft rejection
Graft-versus-host disease
Disease
H00108  
Autoimmune lymphoproliferative syndromes (ALPS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   04010 MAPK signaling pathway
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   04068 FoxO signaling pathway
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   04151 PI3K-Akt signaling pathway
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
  Nervous system
   04722 Neurotrophin signaling pathway
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   05205 Proteoglycans in cancer
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
  Immune diseases
   05320 Autoimmune thyroid disease
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   05330 Allograft rejection
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   05332 Graft-versus-host disease
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
  Infectious diseases
   05162 Measles
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   05164 Influenza A
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   05161 Hepatitis B
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   05168 Herpes simplex infection
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   05142 Chagas disease (American trypanosomiasis)
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
   05143 African trypanosomiasis
    K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
Cytokines [BR:ko04052]
 TNF family
  K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
Cellular antigens [BR:ko04090]
 Proteins
  K04389  CD178, FASLG; tumor necrosis factor (ligand) superfamily, member 6
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
356(FASLG)
PTR: 
469584(FASLG)
PPS: 
100970360(FASLG)
GGO: 
101137781(FASLG)
PON: 
100461418(FASLG)
NLE: 
100597719(FASLG)
MCC: 
574159(FASLG)
MCF: 
102139406(FASLG)
CJC: 
100404850(FASLG)
MMU: 
14103(Fasl)
RNO: 
25385(Faslg)
CGE: 
100773293(Faslg)
NGI: 
103740694(Faslg)
HGL: 
101698642(Faslg)
OCU: 
100344073(FASLG)
TUP: 
102502878(FASLG)
CFA: 
442968(FASLG)
AML: 
UMR: 
103668115(FASLG)
FCA: 
493945(FASLG)
PTG: 
102953222(FASLG)
BTA: 
BOM: 
102281889(FASLG)
PHD: 
102318480(FASLG)
CHX: 
102178753(FASLG)
OAS: 
100135696(FASLG)
SSC: 
396726(FASLG)
CFR: 
102503604(FASLG)
BACU: 
102999836(FASLG)
LVE: 
103073066(FASLG)
ECB: 
100052326(FASLG)
MYB: 
102262076(FASLG)
MYD: 
102759597(FASLG)
PALE: 
102883204(FASLG)
SHR: 
100919776(FASLG)
OAA: 
100081646(FASLG)
GGA: 
429064(FASLG)
MGP: 
APLA: 
101801884(FASLG)
TGU: 
100230435(FASLG)
FAB: 
101820749(FASLG)
PHI: 
102107854(FASLG)
FPG: 
101922036(FASLG)
FCH: 
102046752(FASLG)
CLV: 
102097854(FASLG)
ASN: 
102385618(FASLG)
AMJ: 
PSS: 
102460695(FASLG)
CMY: 
102937724(FASLG)
ACS: 
100554702(faslg)
PBI: 
103051809(FASLG)
XLA: 
100192357(faslg)
XTR: 
100124789(faslg)
DRE: 
735295(faslg)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Gaur U, Aggarwal BB
  Title
Regulation of proliferation, survival and apoptosis by members of the TNF superfamily.
  Journal
Biochem Pharmacol 66:1403-8 (2003)
Reference
  Authors
Bodmer JL, Schneider P, Tschopp J.
  Title
The molecular architecture of the TNF superfamily.
  Journal
Trends Biochem Sci 27:19-26 (2002)

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