KEGG   ORTHOLOGY: K04390Help
Entry
K04390                      KO                                     

Name
TNFRSF6, FAS
Definition
tumor necrosis factor receptor superfamily member 6
Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
p53 signaling pathway
Apoptosis
Natural killer cell mediated cytotoxicity
TNF signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Type I diabetes mellitus
Alzheimer's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Pathways in cancer
Proteoglycans in cancer
Autoimmune thyroid disease
Allograft rejection
Graft-versus-host disease
Disease
H00005  
Chronic lymphocytic leukemia (CLL)
H00007  
Hodgkin lymphoma
H00009  
Adult T-cell leukemia
H00017  
Esophageal cancer
H01463  
Mycosis fungoides
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   04668 TNF signaling pathway
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   04115 p53 signaling pathway
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05205 Proteoglycans in cancer
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
  Immune diseases
   05320 Autoimmune thyroid disease
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05330 Allograft rejection
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05332 Graft-versus-host disease
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
  Infectious diseases
   05162 Measles
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05164 Influenza A
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05161 Hepatitis B
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05168 Herpes simplex infection
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05142 Chagas disease (American trypanosomiasis)
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05143 African trypanosomiasis
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
Cytokine receptors [BR:ko04050]
 TNF receptor family
  K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
Cellular antigens [BR:ko04090]
 Proteins
  K04390  CD95, FAS; tumor necrosis factor receptor superfamily, member 6
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
355(FAS)
PTR: 
738331(FAS)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
574332(FAS)
MCF: 
RRO: 
CJC: 
MMU: 
14102(Fas)
RNO: 
246097(Fas)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
486469(FAS)
AML: 
UMR: 
FCA: 
493881(FAS)
PTG: 
BTA: 
282488(FAS)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
396826(FAS)
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
SHR: 
OAA: 
GGA: 
395274(FAS)
MGP: 
APLA: 
TGU: 
GFR: 
FAB: 
PHI: 
CCW: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XTR: 
DRE: 
768248(fas)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Grivennikov SI, Kuprash DV, Liu ZG, Nedospasov SA
  Title
Intracellular signals and events activated by cytokines of the tumor necrosis factor superfamily: From simple paradigms to complex mechanisms.
  Journal
Int Rev Cytol 252:129-61 (2006)
Reference
  Authors
Riccio M, Carnevale G, Cardinale V, Gibellini L, De Biasi S, Pisciotta A, Carpino G, Gentile R, Berloco PB, Brunelli R, Bastianelli C, Napoletano C, Cantafora A, Cossarizza A, Gaudio E, Alvaro D, De Pol A
  Title
The Fas/Fas ligand apoptosis pathway underlies immunomodulatory properties of human biliary tree stem/progenitor cells.
  Journal
J Hepatol 61:1097-105 (2014)
  Sequence
[hsa:355]

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