KEGG   ORTHOLOGY: K04390Help
Entry
K04390                      KO                                     

Name
TNFRSF6, FAS
Definition
tumor necrosis factor receptor superfamily member 6
Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
p53 signaling pathway
Apoptosis
Natural killer cell mediated cytotoxicity
TNF signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Type I diabetes mellitus
Alzheimer's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Pathways in cancer
Proteoglycans in cancer
Autoimmune thyroid disease
Allograft rejection
Graft-versus-host disease
Disease
H00005  
Chronic lymphocytic leukemia (CLL)
H00007  
Hodgkin lymphoma
H00009  
Adult T-cell leukemia
H00017  
Esophageal cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   04668 TNF signaling pathway
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   04115 p53 signaling pathway
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05205 Proteoglycans in cancer
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
  Immune diseases
   05320 Autoimmune thyroid disease
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05330 Allograft rejection
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05332 Graft-versus-host disease
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
  Infectious diseases
   05162 Measles
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05164 Influenza A
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05161 Hepatitis B
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05168 Herpes simplex infection
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05142 Chagas disease (American trypanosomiasis)
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
   05143 African trypanosomiasis
    K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
Cytokine receptors [BR:ko04050]
 TNF receptor family
  K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
Cellular antigens [BR:ko04090]
 Proteins
  K04390  CD95, FAS; tumor necrosis factor receptor superfamily, member 6
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
355(FAS)
PTR: 
738331(FAS)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
574332(FAS)
MCF: 
CJC: 
MMU: 
14102(Fas)
RNO: 
246097(Fas)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
486469(FAS)
AML: 
UMR: 
FCA: 
493881(FAS)
PTG: 
BTA: 
282488(FAS)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
396826(FAS)
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
OAA: 
GGA: 
395274(FAS)
MGP: 
APLA: 
TGU: 
FAB: 
PHI: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XTR: 
DRE: 
768248(fas)
TRU: 
OLA: 
XMA: 
LCM: 
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Grivennikov SI, Kuprash DV, Liu ZG, Nedospasov SA
  Title
Intracellular signals and events activated by cytokines of the tumor necrosis factor superfamily: From simple paradigms to complex mechanisms.
  Journal
Int Rev Cytol 252:129-61 (2006)

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