KEGG   ORTHOLOGY: K04431Help
Entry
K04431                      KO                                     

Name
MAP2K7, MKK7
Definition
mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
Pathway
MAPK signaling pathway
ErbB signaling pathway
Protein processing in endoplasmic reticulum
Osteoclast differentiation
Toll-like receptor signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
GnRH signaling pathway
Influenza A
Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04012 ErbB signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04668 TNF signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04660 T cell receptor signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04664 Fc epsilon RI signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  Endocrine system
   04912 GnRH signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  Nervous system
   04722 Neurotrophin signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  Development
   04380 Osteoclast differentiation
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 Human Diseases
  Infectious diseases
   05164 Influenza A
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   05169 Epstein-Barr virus infection
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: STE group
  STE7 family
   K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5609(MAP2K7)
PTR: 
743199(MAP2K7)
PPS: 
100989537(MAP2K7)
GGO: 
101124339(MAP2K7)
PON: 
100431600(MAP2K7)
MCC: 
MCF: 
102126975(MAP2K7)
MMU: 
26400(Map2k7)
RNO: 
363855(Map2k7)
CGE: 
100754421(Map2k7)
HGL: 
101710666(Map2k7)
TUP: 
102500732(MAP2K7)
CFA: 
485004(MAP2K7)
AML: 
FCA: 
101095157(MAP2K7)
PTG: 
102949140(MAP2K7)
BTA: 
787278(MAP2K7)
BOM: 
102272638(MAP2K7)
PHD: 
102327200(MAP2K7)
CHX: 
102173178(MAP2K7)
SSC: 
100520418(MAP2K7)
CFR: 
102506459(MAP2K7)
BACU: 
103011683(MAP2K7)
LVE: 
103091499(MAP2K7)
ECB: 
100147230(MAP2K7)
MYB: 
102247950(MAP2K7)
MYD: 
102760954(MAP2K7)
PALE: 
102892533(MAP2K7)
MDO: 
100026752(MAP2K7)
SHR: 
100926110(MAP2K7)
FAB: 
PHI: 
102100701(MAP2K7)
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
102463924(MAP2K7)
CMY: 
102932325(MAP2K7)
ACS: 
PBI: 
XLA: 
394391(map2k7)
XTR: 
613115(map2k7)
DRE: 
560913(map2k7)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103173024(map2k7)
BFO: 
CIN: 
778674(mapkk7)
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
AME: 
413389(hem)
NVI: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG16698(Cbr-mek-1)
BMY: 
LOA: 
NVE: 
HMG: 
TAD: 
AQU: 
POP: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Wang X, Destrument A, Tournier C
  Title
Physiological roles of MKK4 and MKK7: insights from animal models.
  Journal
Biochim Biophys Acta 1773:1349-57 (2007)
Reference
  Authors
Haeusgen W, Herdegen T, Waetzig V
  Title
The bottleneck of JNK signaling: molecular and functional characteristics of MKK4 and MKK7.
  Journal
Eur J Cell Biol 90:536-44 (2011)

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