KEGG   ORTHOLOGY: K04437Help
Entry
K04437                      KO                                     

Name
FLNA
Definition
filamin
Pathway
MAPK signaling pathway
Focal adhesion
Salmonella infection
Proteoglycans in cancer
Disease
H00270  
Periventricular nodular heterotopia (PVNH)
H00456  
Fronto-Otopalatodigital Osteodysplasia
H00461  
FLNB-related disorders
H00499  
Spondylocarpotarsal synostosis syndrome
H00577  
Syndromic X-linked mental retardation with epilepsy or seizures
H00595  
Myofibrillar myopathies (MFM)
H00894  
FG syndrome (FGS)
H01276  
X-linked chronic idiopathic intestinal pseudo-obstruction
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04437  FLNA; filamin
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K04437  FLNA; filamin
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K04437  FLNA; filamin
  Infectious diseases
   05132 Salmonella infection
    K04437  FLNA; filamin
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     K04437  FLNA; filamin
  Intermediate filaments
   Intermediate filament-binding proteins
    K04437  FLNA; filamin
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K04437  FLNA; filamin
BRITE hierarchy
Genes
HSA: 
2316(FLNA) 2317(FLNB) 2318(FLNC)
PTR: 
460476(FLNB) 463711(FLNC) 465940(FLNA)
PPS: 
100980320(FLNA) 100991254(FLNC) 100992733(FLNB)
GGO: 
PON: 
100436976(FLNB) 100446579(FLNA) 100447210(FLNC)
NLE: 
MCC: 
699524(FLNA) 700223(FLNC) 702732(FLNB)
MCF: 
102114837(FLNC) 102134285(FLNB) 102138509(FLNA)
CSAB: 
103226867(FLNC) 103227804(FLNB) 103232822(FLNA)
RRO: 
104660189(FLNB) 104663540(FLNA) 104674436(FLNC)
CJC: 
SBQ: 
101030782(FLNC) 101033199(FLNB) 101038946(FLNA)
MMU: 
192176(Flna) 286940(Flnb) 68794(Flnc)
RNO: 
293860(Flna) 306204(Flnb) 362332(Flnc)
CGE: 
100751994(Flnc) 100760050(Flna) 100769967(Flnb)
NGI: 
HGL: 
101702004(Flna) 101714131(Flnb) 101714775(Flnc)
OCU: 
100008760(FLNB) 100328754(FLNA) 100328756(RA_M006_JSM7BED4F) 100353671(FLNC)
TUP: 
102493536(FLNA) 102497970(FLNB) 102498440(FLNC)
CFA: 
481084(FLNA) 482266(FLNC) 484713(FLNB)
AML: 
100467791(FLNA) 100475857(FLNC) 100481308(FLNB)
UMR: 
103674200(FLNB) 103676641(FLNC) 103679686(FLNA)
FCA: 
PTG: 
102951673(FLNB) 102958609(FLNC) 102969406(FLNA)
BTA: 
281165(FLNA) 528415(FLNC) 613533(FLNB)
BOM: 
102265714(FLNB) 102281567(FLNA) 102287936(FLNC)
PHD: 
102321668(FLNB) 102327369(FLNA) 102329018(FLNC)
CHX: 
102170485(FLNC) 102176601(FLNA) 102187630(FLNB)
OAS: 
SSC: 
100518997(FLNC)
CFR: 
BACU: 
103000025(FLNA) 103001285(FLNC) 103018177(FLNB)
LVE: 
103070633(FLNA) 103082555(FLNB) 103085481(FLNC)
ECB: 
100057963(FLNB) 100058256(FLNA) 100071760(FLNC)
MYB: 
102246018(FLNC) 102255293(FLNB) 102257802(FLNA)
MYD: 
102756703(FLNC) 102761579(FLNB) 102764268(FLNA)
PALE: 
102887099(FLNB) 102889996(FLNA) 102894137(FLNC)
LAV: 
100655159(FLNB) 100666153(FLNC) 100674763(FLNA)
MDO: 
100014156(FLNB) 100014995(FLNC) 100617907(FLNA)
SHR: 
OAA: 
100077046(FLNA) 100078338(FLNC) 100084462(FLNB)
GGA: 
378913(FLNB) 395260(FLNC) 395261(FLNA)
MGP: 
100549125(FLNB)
CJO: 
APLA: 
TGU: 
100224625(FLNC) 100230709(FLNB)
GFR: 
FAB: 
101807613(FLNC) 101815478(FLNB)
PHI: 
102102293(FLNA) 102109930(FLNC) 102113738(FLNB)
CCW: 
104683467(FLNB) 104684619(ATP6V1F)
FPG: 
101914782(FLNB) 101921248(FLNC)
FCH: 
102048385(FLNC) 102055640(FLNB)
CLV: 
AAM: 
ASN: 
102367807(FLNC) 102368306(FLNB) 102370975(FLNA)
AMJ: 
PSS: 
CMY: 
102942474(FLNC) 102947590(FLNB)
ACS: 
PBI: 
103050411(FLNC) 103063627(FLNA) 103064197(FLNB)
GJA: 
XTR: 
100329116(flnc) 100485165(flnb) 779840(flna)
DRE: 
100048921(flnca) 562529(flna) 563023(flnb) 569979(flnbl) 570288(flncb)
TRU: 
TNG: 
MZE: 
OLA: 
XMA: 
SASA: 
LCM: 
102345455(FLNA) 102352444(FLNC) 102360310(FLNB)
CMK: 
103190015(flnc) 103190036(flnb)
BFO: 
CIN: 
SPU: 
579510(flnb) 587317(FLNA)
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD15083(Dsim_GD15083) Dsimw501_GD20251(Dsim_GD20251) Dsimw501_GD25106(Dsim_GD25106)
DWI: 
DYA: 
Dyak_GE10575(dyak_GLEANR_10488) Dyak_GE11838(dyak_GLEANR_12136) Dyak_GE26108(dyak_GLEANR_9680)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
409697(GB13109) 410171 552466(GB14141)
BIM: 
BTER: 
SOC: 
AEC: 
HST: 
105180971(Filamin-C) 105182494(Filamin-B)
CFO: 
105247995 105249451(Filamin-B)
NVI: 
TCA: 
BMOR: 
DPL: 
PXY: 
API: 
PHU: 
DPX: 
ISC: 
CEL: 
CBR: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
105323404 105325934(Filamin-C) 105327611(Filamin-A) 105327831(Filamin-A) 105346068(Filamin-A) 105348068(Filamin-C)
OBI: 
SMM: 
NVE: 
ADF: 
HMG: 
TAD: 
AQU: 
SMO: 
CSL: 
DDI: 
DPP: 
DFA: 
DFA_01474(abpC)
EHI: 
EHI_104630(3.t00014)
EDI: 
EIV: 
ACAN: 
AAF: 
PIF: 
PSOJ: 
GTT: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Adams M, Simms RJ, Abdelhamed Z, Dawe HR, Szymanska K, Logan CV, Wheway G, Pitt E, Gull K, Knowles MA, Blair E, Cross SH, Sayer JA, Johnson CA
  Title
A meckelin-filamin A interaction mediates ciliogenesis.
  Journal
Hum Mol Genet 21:1272-86 (2012)
  Sequence
[hsa:2316] [mmu:192176]

DBGET integrated database retrieval system