KEGG   ORTHOLOGY: K04441Help
Entry
K04441                      KO                                     

Name
P38
Definition
p38 MAP kinase [EC:2.7.11.24]
Pathway
MAPK signaling pathway
MAPK signaling pathway - yeast
Rap1 signaling pathway
FoxO signaling pathway
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Amyotrophic lateral sclerosis (ALS)
Epithelial cell signaling in Helicobacter pylori infection
Shigellosis
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Influenza A
Epstein-Barr virus infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K04441  P38; p38 MAP kinase
   04010 MAPK signaling pathway
    K04441  P38; p38 MAP kinase
   04011 MAPK signaling pathway - yeast
    K04441  P38; p38 MAP kinase
   04370 VEGF signaling pathway
    K04441  P38; p38 MAP kinase
   04668 TNF signaling pathway
    K04441  P38; p38 MAP kinase
   04068 FoxO signaling pathway
    K04441  P38; p38 MAP kinase
 Cellular Processes
  Cellular commiunity
   04550 Signaling pathways regulating pluripotency of stem cells
    K04441  P38; p38 MAP kinase
 Organismal Systems
  Immune system
   04611 Platelet activation
    K04441  P38; p38 MAP kinase
   04620 Toll-like receptor signaling pathway
    K04441  P38; p38 MAP kinase
   04621 NOD-like receptor signaling pathway
    K04441  P38; p38 MAP kinase
   04622 RIG-I-like receptor signaling pathway
    K04441  P38; p38 MAP kinase
   04660 T cell receptor signaling pathway
    K04441  P38; p38 MAP kinase
   04664 Fc epsilon RI signaling pathway
    K04441  P38; p38 MAP kinase
   04670 Leukocyte transendothelial migration
    K04441  P38; p38 MAP kinase
  Endocrine system
   04912 GnRH signaling pathway
    K04441  P38; p38 MAP kinase
   04914 Progesterone-mediated oocyte maturation
    K04441  P38; p38 MAP kinase
   04917 Prolactin signaling pathway
    K04441  P38; p38 MAP kinase
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04441  P38; p38 MAP kinase
  Nervous system
   04728 Dopaminergic synapse
    K04441  P38; p38 MAP kinase
   04723 Retrograde endocannabinoid signaling
    K04441  P38; p38 MAP kinase
   04722 Neurotrophin signaling pathway
    K04441  P38; p38 MAP kinase
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04441  P38; p38 MAP kinase
  Development
   04380 Osteoclast differentiation
    K04441  P38; p38 MAP kinase
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K04441  P38; p38 MAP kinase
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    K04441  P38; p38 MAP kinase
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04441  P38; p38 MAP kinase
   05132 Salmonella infection
    K04441  P38; p38 MAP kinase
   05131 Shigellosis
    K04441  P38; p38 MAP kinase
   05133 Pertussis
    K04441  P38; p38 MAP kinase
   05152 Tuberculosis
    K04441  P38; p38 MAP kinase
   05164 Influenza A
    K04441  P38; p38 MAP kinase
   05160 Hepatitis C
    K04441  P38; p38 MAP kinase
   05169 Epstein-Barr virus infection
    K04441  P38; p38 MAP kinase
   05145 Toxoplasmosis
    K04441  P38; p38 MAP kinase
   05140 Leishmaniasis
    K04441  P38; p38 MAP kinase
   05142 Chagas disease (American trypanosomiasis)
    K04441  P38; p38 MAP kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     K04441  P38; p38 MAP kinase
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   K04441  P38; p38 MAP kinase
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
1432(MAPK14) 5600(MAPK11) 5603(MAPK13) 6300(MAPK12)
PTR: 
450161(MAPK14) 462644(MAPK13) 747077(MAPK12)
PPS: 
100980937(MAPK11) 100981268(MAPK12) 100982544(MAPK13) 100983649(MAPK14)
GGO: 
101134492(MAPK12) 101134843(MAPK11) 101148438(MAPK13) 101152640(MAPK14)
PON: 
100437263(MAPK12) 100449269(MAPK14) 100449853(MAPK13)
MCC: 
715745(MAPK12) 715794(MAPK11) 718976 719085
MCF: 
MMU: 
19094(Mapk11) 26415(Mapk13) 26416(Mapk14) 29857(Mapk12)
RNO: 
29513(Mapk13) 60352(Mapk12) 689314(Mapk11) 81649(Mapk14)
CGE: 
100689104(Mapk14) 100754042(Mapk12) 100759172(Mapk11) 100763519(Mapk13)
HGL: 
101705370(Mapk11) 101706002(Mapk12) 101715692(Mapk14)
TUP: 
102481241(MAPK13) 102487603(MAPK11) 102495693(MAPK14) 102501733(MAPK12)
CFA: 
403856(MAPK14) 607019(MAPK11) 607023(MAPK12) 612821(MAPK13)
AML: 
FCA: 
101081396(MAPK11) 101091536(MAPK13) 101101135(MAPK14)
PTG: 
102960306(MAPK12) 102960590(MAPK11) 102968191(MAPK13) 102968482(MAPK14)
BTA: 
512943(MAPK12) 534492(MAPK14) 535327(MAPK13) 618906(MAPK11)
BOM: 
102271030(MAPK13) 102271320(MAPK14) 102285848(MAPK12)
PHD: 
102321680(MAPK13) 102322031(MAPK14) 102331873(MAPK12)
CHX: 
100860996(MAPK13) 102180926(MAPK12) 102184510(MAPK11) 102189174(MAPK14)
OAS: 
100194428(MAPK13) 100217411(MAPK14) 101115956(MAPK12) 101116223
SSC: 
100156630(MAPK14) 574062(MAPK12)
CFR: 
102511078(MAPK14) 102511298(MAPK13) 102516847(MAPK12) 102519781(MAPK11)
BACU: 
102999798 103002378(MAPK13) 103008537(MAPK14) 103009561(MAPK11) 103009947(MAPK12)
LVE: 
103077530(MAPK12) 103078049(MAPK14) 103078710(MAPK13) 103083209(MAPK11)
ECB: 
100056239(MAPK12) 100056278(MAPK11) 100063532(MAPK14)
MYB: 
102248097 102254628(MAPK12) 102254920(MAPK11)
MYD: 
102755728(MAPK14) 102756012(MAPK13) 102770021(MAPK12) 102770309(MAPK11)
PALE: 
102877720(MAPK13) 102888602(MAPK11) 102888845(MAPK12) 102895900(MAPK14)
MDO: 
100010279(MAPK12) 100010891(MAPK11) 100026324(MAPK14) 100028821(MAPK13)
SHR: 
100925013(MAPK14) 100925447(MAPK13) 100928729(MAPK12) 100928990(MAPK11)
OAA: 
GGA: 
417739(MAPK11) 421183(MAPK14) 769763(MAPK12) 771145(MAPK13)
MGP: 
TGU: 
FAB: 
101807358(MAPK12) 101814783(MAPK11) 101817434(MAPK13) 101819980(MAPK14)
PHI: 
102109820(MAPK11) 102110009(MAPK12) 102110807(MAPK13) 102111004(MAPK14)
APLA: 
101792057(MAPK11) 101793591(MAPK12) 101802116(MAPK13) 101805023(MAPK14)
FPG: 
101920170(MAPK12) 101920353(MAPK11) 101921635(MAPK14) 101922433(MAPK13)
FCH: 
102051874(MAPK12) 102052038(MAPK11) 102054359(MAPK13) 102059377(MAPK14)
CLV: 
ASN: 
102374196(MAPK12) 102375835(MAPK11) 102375954(MAPK13) 102376541(MAPK14)
AMJ: 
102565123(MAPK13) 102565670(MAPK14) 102571177(MAPK11) 102571419(MAPK12)
PSS: 
102448785(MAPK14) 102455939(MAPK13) 102462429(MAPK11) 102462672(MAPK12)
CMY: 
102934859(MAPK14) 102938087(MAPK11) 102940215(MAPK12) 102941338(MAPK13)
ACS: 
100563538(mapk12) 100563731(mapk11) 100567479(mapk13) 100567676(mapk14)
PBI: 
103053438(MAPK14) 103053997(MAPK13) 103063187(MAPK12) 103063888(MAPK11)
XLA: 
100329215(p38-beta) 379992(mapk14) 398592(mapk12) 494669(mapk11) 735153
XTR: 
100101766(mapk11) 100144715(mapk13) 100145045(mapk12) 448296(mapk14) 549834(mapk12)
DRE: 
100002318(mapk13) 266756(mapk14b) 30681(mapk12a) 415185(mapk11) 557810(mapk12b) 562552(fc89f08) 65237(mapk14a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
778927(p38)
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AAG: 
CQU: 
AME: 
411915(p38b)
NVI: 
100114440(P38mapk)
TCA: 
BMOR: 
692545(P38mapk)
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG01554(Cbr-pmk-2) CBG01555(Cbr-pmk-1)
BMY: 
LOA: 
TSP: 
NVE: 
HMG: 
TAD: 
AQU: 
SCE: 
YLR113W(HOG1)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0C03380(NCAS0C03380)
NDI: 
NDAI_0G02700(NDAI0G02700)
TPF: 
TPHA_0A01630(TPHA0A01630)
TBL: 
TBLA_0H01330(TBLA0H01330)
TDL: 
TDEL_0F04290(TDEL0F04290)
KAF: 
KAFR_0B02980(KAFR0B02980)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CaO19.8514(HOG1) CaO19.895(HOG1)
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
ANG: 
ANI_1_492064(An07g03980) ANI_1_826074(An08g05850)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
PPL: 
DSQ: 
SHS: 
PCO: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT22411(AGABI1DRAFT_22411)
ABV: 
AGABI2DRAFT41003(AGABI2DRAFT_41003)
CPUT: 
SLA: 
UMA: 
PFP: 
MGL: 
PGR: 
MLR: 
WSE: 
MBR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cuadrado A, Nebreda AR
  Title
Mechanisms and functions of p38 MAPK signalling.
  Journal
Biochem J 429:403-17 (2010)

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