KEGG   ORTHOLOGY: K04450Help
Entry
K04450                      KO                                     

Name
ATF2, CREBP1
Definition
cyclic AMP-dependent transcription factor ATF-2
Pathway
MAPK signaling pathway
MAPK signaling pathway - fly
cGMP-PKG signaling pathway
PI3K-Akt signaling pathway
Longevity regulating pathway
Adrenergic signaling in cardiomyocytes
TNF signaling pathway
Dopaminergic synapse
Insulin secretion
Estrogen signaling pathway
Thyroid hormone synthesis
Glucagon signaling pathway
Aldosterone synthesis and secretion
Cocaine addiction
Amphetamine addiction
Alcoholism
Hepatitis B
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04013 MAPK signaling pathway - fly
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04668 TNF signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04022 cGMP - PKG signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04151 PI3K-Akt signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04922 Glucagon signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04915 Estrogen signaling pathway
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04918 Thyroid hormone synthesis
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   04925 Aldosterone synthesis and secretion
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  Nervous system
   04728 Dopaminergic synapse
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  Aging
   04211 Longevity regulating pathway - mammal
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  Substance dependence
   05030 Cocaine addiction
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   05031 Amphetamine addiction
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   05034 Alcoholism
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
  Infectious diseases
   05166 HTLV-I infection
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   05164 Influenza A
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   05161 Hepatitis B
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
   05169 Epstein-Barr virus infection
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
1386(ATF2)
PTR: 
101059354(ATF2)
PPS: 
100985706(ATF2)
GGO: 
101135003(ATF2)
PON: 
100450554(ATF2)
NLE: 
100582751(ATF2)
MCC: 
699072(ATF2)
MCF: 
101925838(ATF2)
RRO: 
104672399(ATF2)
CJC: 
100414156(ATF2)
MMU: 
RNO: 
81647(Atf2)
CGE: 
100754663(Atf2)
NGI: 
103751761(Atf2)
HGL: 
101717365(Atf2)
OCU: 
100355367(ATF2)
TUP: 
102473406(ATF2)
CFA: 
478806(ATF2)
AML: 
100474135(ATF2)
UMR: 
103659593(ATF2)
FCA: 
101090884(ATF2)
PTG: 
102954603(ATF2)
BTA: 
509827(ATF2)
BOM: 
102283891(ATF2)
PHD: 
102335809(ATF2)
CHX: 
102180634(ATF2)
OAS: 
101108548(ATF2)
SSC: 
100513441(ATF2)
CFR: 
102512476(ATF2)
BACU: 
102999133(ATF2)
LVE: 
103089070(ATF2)
ECB: 
100053304(ATF2)
MYB: 
102241887(ATF2)
MYD: 
102761389(ATF2)
PALE: 
102889014(ATF2)
MDO: 
100025939(ATF2)
SHR: 
100914193(ATF2)
OAA: 
100077942(ATF2)
GGA: 
395727(ATF2)
MGP: 
100549420(ATF2)
APLA: 
101800932(ATF2)
TGU: 
100226584(ATF2)
GFR: 
102034606(ATF2)
FAB: 
101812575(ATF2)
PHI: 
102105113(ATF2)
CCW: 
104693853(ATF2)
FPG: 
101912040(ATF2)
FCH: 
102052727(ATF2)
CLV: 
102084432(ATF2)
ASN: 
102387336(ATF2)
AMJ: 
102572172(ATF2)
PSS: 
102460331(ATF2)
CMY: 
102939131(ATF2)
ACS: 
100557710(atf2)
PBI: 
103053462(ATF2)
XLA: 
378533(atf2)
XTR: 
100485532(atf2)
DRE: 
100006516(atf2) 567018(atf7b)
TRU: 
101063333(atf2)
MZE: 
101463949(atf2)
OLA: 
101161843(atf2)
XMA: 
102234028(atf2)
LCM: 
CMK: 
103176469(atf2)
BFO: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
Dyak_GE14449(dyak_GLEANR_14569)
DGR: 
DVI: 
MDE: 
AGA: 
AAG: 
AaeL_AAEL013261(AAEL801171)
CQU: 
AME: 
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
BMOR: 
PXY: 
PHU: 
ISC: 
HRO: 
LGI: 
CRG: 
OBI: 
NVE: 
HMG: 
TAD: 
AQU: 
VCN: 
APRO: 
MTM: 
MAW: 
MAJ: 
CMT: 
VDA: 
ACT: 
BZE: 
BSC: 
BOR: 
PFJ: 
NPA: 
PGR: 
MLR: 
SRE: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2529117
  Authors
Maekawa T, Sakura H, Kanei-Ishii C, Sudo T, Yoshimura T, Fujisawa J, Yoshida M, Ishii S
  Title
Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain.
  Journal
EMBO J 8:2023-8 (1989)
  Sequence
[hsa:1386]
Reference
  Authors
Kawasaki H, Schiltz L, Chiu R, Itakura K, Taira K, Nakatani Y, Yokoyama KK
  Title
ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation.
  Journal
Nature 405:195-200 (2000)
  Sequence
[hsa:1386]

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