KEGG   ORTHOLOGY: K04498Help
Entry
K04498                      KO                                     
Name
EP300, CREBBP, KAT3
Definition
E1A/CREB-binding protein [EC:2.3.1.48]
Pathway
HIF-1 signaling pathway
Cell cycle
Wnt signaling pathway
Notch signaling pathway
TGF-beta signaling pathway
Adherens junction
Jak-STAT signaling pathway
Long-term potentiation
Melanogenesis
Huntington's disease
Tuberculosis
Hepatitis B
Influenza A
HTLV-I infection
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Renal cell carcinoma
Prostate cancer
Disease
H00504  
Rubinstein-Taybi syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   04330 Notch signaling pathway
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   04350 TGF-beta signaling pathway
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   04630 Jak-STAT signaling pathway
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   04066 HIF-1 signaling pathway
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
  Cell communication
   04520 Adherens junction
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
 Organismal Systems
  Endocrine system
   04916 Melanogenesis
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
  Nervous system
   04720 Long-term potentiation
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   05203 Viral carcinogenesis
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   05211 Renal cell carcinoma
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   05215 Prostate cancer
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
  Neurodegenerative diseases
   05016 Huntington's disease
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
  Infectious diseases
   05152 Tuberculosis
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   05166 HTLV-I infection
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   05164 Influenza A
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   05161 Hepatitis B
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   05168 Herpes simplex infection
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
   05169 Epstein-Barr virus infection
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Other transcription factors
   Pocket domain CBP
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
Chromosome [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HATs (histone acetyltransferases)
    K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein
BRITE hierarchy
Genes
HSA: 
1387(CREBBP) 2033(EP300)
PTR: 
458862(EP300) 467891(CREBBP)
PPS: 
100983185(EP300) 100984888(CREBBP)
GGO: 
101144808(CREBBP) 101153383(EP300)
PON: 
100445634(CREBBP) 100455260(EP300)
MCC: 
704331(CREBBP) 706258(EP300)
MMU: 
12914(Crebbp) 328572(Ep300)
RNO: 
170915(Ep300) 54244(Crebbp)
CFA: 
100684945(EP300) 479866(CREBBP)
AML: 
FCA: 
101088344(EP300) 101094471(CREBBP)
BTA: 
505453(CREBBP) 784935
SSC: 
100156226(EP300)
ECB: 
100055626(EP300) 100069613(CREBBP)
MDO: 
100013876(CREBBP) 100028102(EP300)
SHR: 
100921187(EP300) 100926283(CREBBP)
OAA: 
100080510
GGA: 
416667(CREBBP) 418000(EP300)
MGP: 
100542241 100543704(EP300)
TGU: 
100227395(CREBBP) 100231106(EP300)
ACS: 
100566746(ep300)
XLA: 
495689(crebbp-b)
XTR: 
100101677(crebbp) 734023(ep300)
DRE: 
100535787(crebbp) 559273(ep300a) 565612(ep300b)
TRU: 
101070643 101073984 101078373 446056(ep300)
OLA: 
101163392 101168870
BFO: 
BRAFLDRAFT_126580
CIN: 
778561(cbp)
SPU: 
577224
DME: 
Dmel_CG15319(nej)
DPO: 
Dpse_GA13644
DAN: 
Dana_GF22418
DER: 
Dere_GG18963
DSE: 
Dsec_GM11349
DSI: 
Dsim_GD16050
DWI: 
Dwil_GK25575
DYA: 
Dyak_GE15438
DGR: 
Dgri_GH12924
DMO: 
Dmoj_GI14627
DVI: 
Dvir_GJ19060
AGA: 
AgaP_AGAP000029
CQU: 
CpipJ_CPIJ005540
NVI: 
100123220(Crebbp)
TCA: 
664565
API: 
100162127
PHU: 
Phum_PHUM086710
ISC: 
IscW_ISCW021822
CBR: 
CBG09974(Cbr-cbp-1)
BMY: 
Bm1_18500
TSP: 
Tsp_00559
SMM: 
Smp_105910
NVE: 
NEMVE_v1g106064
HMG: 
100203474
TAD: 
TRIADDRAFT_60973
AQU: 
100638672
ATH: 
AT1G16710(HAC12) AT1G55970(HAC4) AT1G67220(HAC2) AT1G79000(HAC1) AT3G12980(HAC5)
ALY: 
ARALYDRAFT_337685 ARALYDRAFT_477069 ARALYDRAFT_679406 ARALYDRAFT_894451 ARALYDRAFT_897509
GMX: 
100787114 100809207
MTR: 
MTR_4g005050
CSV: 
101214744
RCU: 
RCOM_1573230
POP: 
POPTR_803030(HAC901) POPTR_828090(HAC902)
VVI: 
100251243
OSA: 
4326755 4328238 4341999
DOSA: 
Os01t0246100-01(Os01g0246100) Os02t0137500-01(Os02g0137500)
BDI: 
100845345 100845513
SBI: 
SORBI_04g003020(SORBIDRAFT_04g003020) SORBI_08g019950(SORBIDRAFT_08g019950)
ZMA: 
100273924
SMO: 
SELMODRAFT_185373 SELMODRAFT_422911
PPP: 
PHYPADRAFT_10108(HAC1501) PHYPADRAFT_52(HAC1502)
CRE: 
CHLREDRAFT_145462
VCN: 
VOLCADRAFT_121714
OLU: 
OSTLU_24443(HAC3501)
OTA: 
Ot04g03660
MBR: 
MONBRDRAFT_9670
PTI: 
PHATRDRAFT_45764 PHATRDRAFT_54505
TPS: 
THAPSDRAFT_24331
PIF: 
PITG_07302
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Braganca J, Eloranta JJ, Bamforth SD, Ibbitt JC, Hurst HC, Bhattacharya S
  Title
Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2.
  Journal
J Biol Chem 278:16021-9 (2003)
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