KEGG   ORTHOLOGY: K04513Help
Entry
K04513                      KO                                     

Name
RHOA
Definition
Ras homolog gene family, member A
Pathway
MAPK signaling pathway - yeast
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
Sphingolipid signaling pathway
Phospholipase D signaling pathway
Endocytosis
mTOR signaling pathway
Vascular smooth muscle contraction
Wnt signaling pathway
TGF-beta signaling pathway
Axon guidance
Focal adhesion
Adherens junction
Tight junction
Platelet activation
T cell receptor signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Oxytocin signaling pathway
Pancreatic secretion
Bacterial invasion of epithelial cells
Pathogenic Escherichia coli infection
Pertussis
Tuberculosis
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
MicroRNAs in cancer
Colorectal cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
   04015 Rap1 signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
   04011 MAPK signaling pathway - yeast
    K04513  RHOA; Ras homolog gene family, member A
   04310 Wnt signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
   04350 TGF-beta signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
   04072 Phospholipase D signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
   04071 Sphingolipid signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
   04024 cAMP signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
   04022 cGMP - PKG signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
   04150 mTOR signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K04513  RHOA; Ras homolog gene family, member A
  Cell motility
   04810 Regulation of actin cytoskeleton
    K04513  RHOA; Ras homolog gene family, member A
  Cellular community
   04510 Focal adhesion
    K04513  RHOA; Ras homolog gene family, member A
   04520 Adherens junction
    K04513  RHOA; Ras homolog gene family, member A
   04530 Tight junction
    K04513  RHOA; Ras homolog gene family, member A
 Organismal Systems
  Immune system
   04611 Platelet activation
    K04513  RHOA; Ras homolog gene family, member A
   04660 T cell receptor signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
   04670 Leukocyte transendothelial migration
    K04513  RHOA; Ras homolog gene family, member A
   04062 Chemokine signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
  Endocrine system
   04921 Oxytocin signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
  Circulatory system
   04270 Vascular smooth muscle contraction
    K04513  RHOA; Ras homolog gene family, member A
  Digestive system
   04972 Pancreatic secretion
    K04513  RHOA; Ras homolog gene family, member A
  Nervous system
   04722 Neurotrophin signaling pathway
    K04513  RHOA; Ras homolog gene family, member A
  Development
   04360 Axon guidance
    K04513  RHOA; Ras homolog gene family, member A
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04513  RHOA; Ras homolog gene family, member A
   05206 MicroRNAs in cancer
    K04513  RHOA; Ras homolog gene family, member A
   05205 Proteoglycans in cancer
    K04513  RHOA; Ras homolog gene family, member A
   05203 Viral carcinogenesis
    K04513  RHOA; Ras homolog gene family, member A
   05210 Colorectal cancer
    K04513  RHOA; Ras homolog gene family, member A
  Infectious diseases
   05130 Pathogenic Escherichia coli infection
    K04513  RHOA; Ras homolog gene family, member A
   05133 Pertussis
    K04513  RHOA; Ras homolog gene family, member A
   05152 Tuberculosis
    K04513  RHOA; Ras homolog gene family, member A
   05100 Bacterial invasion of epithelial cells
    K04513  RHOA; Ras homolog gene family, member A
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K04513  RHOA; Ras homolog gene family, member A
  Exosomal proteins of other body fluids (saliva and urine)
   K04513  RHOA; Ras homolog gene family, member A
  Exosomal proteins of colorectal cancer cells
   K04513  RHOA; Ras homolog gene family, member A
  Exosomal proteins of bladder cancer cells
   K04513  RHOA; Ras homolog gene family, member A
GTP-binding proteins [BR:ko04031]
 Small (Monomeric) G-proteins
  Rho Family
   RhoA/B/C [OT]
    K04513  RHOA; Ras homolog gene family, member A
BRITE hierarchy
Other DBs
COG: 
Genes
HSA: 
387(RHOA)
PTR: 
461014(RHOA)
PPS: 
100995642(RHOA)
GGO: 
PON: 
100171605(RHOA)
NLE: 
MCC: 
706455(RHOA)
MCF: 
101865630(RHOA)
RRO: 
104667372(RHOA)
CJC: 
100393236(RHOA)
MMU: 
11848(Rhoa) 67653(4930544G11Rik)
RNO: 
117273(Rhoa) 297173(RSA-14-44)
CGE: 
NGI: 
103750189(Rhoa)
HGL: 
101710109(Rhoa)
OCU: 
TUP: 
102487039(RHOA)
CFA: 
403954(RHOA)
AML: 
100476723(RHOA)
UMR: 
103674825(RHOA)
FCA: 
101084011(RHOA)
PTG: 
102952555(RHOA)
BTA: 
338049(RHOA)
BOM: 
102280554(RHOA)
PHD: 
102341767(RHOA)
CHX: 
102181169(RHOA)
OAS: 
100302078(RHOA)
SSC: 
396849(RHOA)
CFR: 
102507993(RHOA)
BACU: 
103019793(RHOA)
LVE: 
103074732(RHOA)
ECB: 
100053343(RHOA)
MYB: 
102244315(RHOA)
MYD: 
PALE: 
102891515(RHOA)
MDO: 
100021110(RHOA)
SHR: 
100921931(RHOA)
OAA: 
GGA: 
395442(RHOA)
MGP: 
100547488(RHOA)
CJO: 
107319611(RHOA)
APLA: 
TGU: 
100190386(RHOA)
GFR: 
102034459(RHOA)
FAB: 
101806310(RHOA)
PHI: 
102104637(RHOA)
CCW: 
104683253(RHOA)
FPG: 
101911200(RHOA)
FCH: 
102049160(RHOA) 102053607(RHOC)
CLV: 
102086675(RHOA)
AAM: 
106491145(RHOA)
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
GJA: 
XLA: 
379326(rhoc) 379416(rhoa-a) 380133(rhoa-b)
XTR: 
448080(rhoa) 549323(rhoc) 549402(rhoa.2)
DRE: 
100006041(rhoab) 406411(rhoaa) 406659(rhoac) 436718(rhocb) 751630
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
445700(rhoc) 493871(rhoa)
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD11158(Dsim_GD11158)
DWI: 
DYA: 
Dyak_GE11751(dyak_GLEANR_12057)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
409910(Rho1)
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
100114100(RHOA)
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG13664(Cbr-rho-1)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
SCE: 
YPR165W(RHO1)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0A15070(NCAS0A15070) NCAS_0H00220(NCAS0H00220)
NDI: 
NDAI_0D00180(NDAI0D00180) NDAI_0J00230(NDAI0J00230)
TPF: 
TPHA_0I03130(TPHA0I03130) TPHA_0I03140(TPHA0I03140)
TBL: 
TBLA_0J00210(TBLA0J00210)
TDL: 
TDEL_0H00500(TDEL0H00500)
KAF: 
KAFR_0A03120(KAFR0A03120) KAFR_0B00480(KAFR0B00480)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
NCR: 
NCU01484(rho-1)
NTE: 
NEUTE1DRAFT117265(NEUTE1DRAFT_117265)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_124154(AO090003000071)
ANG: 
ANI_1_802164(An18g05980)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
DSQ: 
PCO: 
SHS: 
HIR: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MPR: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT87772(AGABI1DRAFT_87772)
ABV: 
AGABI2DRAFT139932(AGABI2DRAFT_139932)
CPUT: 
SLA: 
WSE: 
WIC: 
UMA: 
PFP: 
MGL: 
MLR: 
ECU: 
EIN: 
EHE: 
ERO: 
NCE: 
MBR: 
SRE: 
DPP: 
EIV: 
AAF: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Stirling L, Williams MR, Morielli AD
  Title
Dual roles for RHOA/RHO-kinase in the regulated trafficking of a voltage-sensitive potassium channel.
  Journal
Mol Biol Cell 20:2991-3002 (2009)
  Sequence
[hsa:387]
Reference
PMID:8195291
  Authors
Yamochi W, Tanaka K, Nonaka H, Maeda A, Musha T, Takai Y
  Title
Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae.
  Journal
J Cell Biol 125:1077-93 (1994)
  Sequence
[sce:YPR165W]
Reference
PMID:8039707
  Authors
Moscow JA, He R, Gudas JM, Cowan KH
  Title
Utilization of multiple polyadenylation signals in the human RHOA protooncogene.
  Journal
Gene 144:229-36 (1994)
  Sequence
[hsa:387]

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