KEGG   ORTHOLOGY: K04527Help
Entry
K04527                      KO                                     

Name
INSR
Definition
insulin receptor [EC:2.7.10.1]
Pathway
Ras signaling pathway
Rap1 signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Disease
H00719  
Leprechaunism
H00942  
Rabson-Mendenhall syndrome
H01228  
Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN)
H01267  
Familial hyperinsulinemic hypoglycemia (HHF)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K04527  INSR; insulin receptor
   04015 Rap1 signaling pathway
    K04527  INSR; insulin receptor
   04066 HIF-1 signaling pathway
    K04527  INSR; insulin receptor
   04068 FoxO signaling pathway
    K04527  INSR; insulin receptor
   04151 PI3K-Akt signaling pathway
    K04527  INSR; insulin receptor
 Cellular Processes
  Cell communication
   04520 Adherens junction
    K04527  INSR; insulin receptor
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K04527  INSR; insulin receptor
   04913 Ovarian Steroidogenesis
    K04527  INSR; insulin receptor
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K04527  INSR; insulin receptor
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04527  INSR; insulin receptor
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04527  INSR; insulin receptor
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K04527  INSR; insulin receptor
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  InsR family [Table]
   K04527  INSR; insulin receptor
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   K04527  INSR; insulin receptor
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   K04527  INSR; insulin receptor
Cellular antigens [BR:ko04090]
 Proteins
  K04527  CD220, INSR; insulin receptor
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3643(INSR)
PTR: 
455649(INSR)
PPS: 
100991905(INSR)
GGO: 
101144696(INSR)
MCC: 
706009(INSR)
MCF: 
102139081(INSR)
MMU: 
16337(Insr)
RNO: 
24954(Insr)
CGE: 
HGL: 
101722168(Insr)
TUP: 
102469167(INSR)
CFA: 
484990(INSR)
AML: 
100473956(INSR)
FCA: 
100127108(INSR)
BTA: 
408017(INSR)
BOM: 
102285317(INSR)
PHD: 
102344118(INSR)
CHX: 
102168996(INSR)
SSC: 
396755(INSR)
CFR: 
102522017(INSR)
ECB: 
100066248(INSR)
MYB: 
MDO: 
100027215(INSR)
SHR: 
100929204(INSR)
OAA: 
100079104(INSR)
GGA: 
420133(INSR)
MGP: 
100550007(INSR)
TGU: 
FAB: 
101813861(INSR)
PHI: 
102105828(INSR)
APLA: 
101795803(INSR)
FPG: 
101914421(INSR)
FCH: 
102056291(INSR)
CLV: 
102085804(INSR)
ASN: 
102378715(INSR)
PSS: 
XLA: 
398006(insr)
XTR: 
DRE: 
245699(insra) 245700(insrb)
TRU: 
MZE: 
OLA: 
XMA: 
BFO: 
CIN: 
778651(insulinr)
SPU: 
579152(ir)
DGR: 
DVI: 
AGA: 
AAG: 
AME: 
411297(IR-B) 725827(InR-2)
NVI: 
100122567(INSR)
TCA: 
BMOR: 
692560(InR)
API: 
PHU: 
CBR: 
CBG15732(Cbr-daf-2)
TSP: 
NVE: 
TAD: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Krook A, Wallberg-Henriksson H, Zierath JR
  Title
Sending the signal: molecular mechanisms regulating glucose uptake.
  Journal
Med Sci Sports Exerc 36:1212-7 (2004)

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