KEGG   ORTHOLOGY: K04634Help
Entry
K04634                      KO                                     

Name
GNAQ
Definition
guanine nucleotide-binding protein G(q) subunit alpha
Pathway
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Sphingolipid signaling pathway
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Phototransduction - fly
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Glucagon signaling pathway
Renin secretion
Aldosterone synthesis and secretion
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04020 Calcium signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04071 Sphingolipid signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04022 cGMP - PKG signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
 Cellular Processes
  Cellular community
   04540 Gap junction
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
 Organismal Systems
  Immune system
   04611 Platelet activation
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  Endocrine system
   04911 Insulin secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04922 Glucagon signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04912 GnRH signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04915 Estrogen signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04921 Oxytocin signaling pathway
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04918 Thyroid hormone synthesis
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04916 Melanogenesis
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04924 Renin secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04925 Aldosterone synthesis and secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04270 Vascular smooth muscle contraction
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  Digestive system
   04970 Salivary secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04971 Gastric acid secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04972 Pancreatic secretion
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  Nervous system
   04724 Glutamatergic synapse
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04725 Cholinergic synapse
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04728 Dopaminergic synapse
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04726 Serotonergic synapse
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04720 Long-term potentiation
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04730 Long-term depression
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04723 Retrograde endocannabinoid signaling
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  Sensory system
   04745 Phototransduction - fly
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   04750 Inflammatory mediator regulation of TRP channels
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  Environmental adaptation
   04713 Circadian entrainment
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   05016 Huntington's disease
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
  Infectious diseases
   05146 Amoebiasis
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   05142 Chagas disease (American trypanosomiasis)
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
   05143 African trypanosomiasis
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
GTP-binding proteins [BR:ko04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 3 (Gq/11) [OT]
    K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
BRITE hierarchy
Genes
HSA: 
2776(GNAQ)
PTR: 
472962(GNAQ)
PPS: 
100986730(GNAQ)
GGO: 
PON: 
100458686(GNAQ)
NLE: 
100594473(GNAQ)
MCC: 
705680(GNAQ)
MCF: 
102130397(GNAQ)
CSAB: 
103219624(GNAQ)
RRO: 
CJC: 
100403006(GNAQ)
SBQ: 
101051855(GNAQ)
MMU: 
14682(Gnaq)
RNO: 
81666(Gnaq)
CGE: 
100689066(Gnaq)
NGI: 
103734421(Gnaq)
HGL: 
101715420(Gnaq)
OCU: 
100340719(GNAQ)
TUP: 
102468263(GNAQ)
CFA: 
403928(GNAQ)
AML: 
100464853(GNAQ)
UMR: 
103663281(GNAQ)
FCA: 
101094708(GNAQ)
PTG: 
102954227(GNAQ)
BTA: 
536654(GNAQ)
BOM: 
102287414(GNAQ)
PHD: 
102316799(GNAQ)
CHX: 
102189950(GNAQ)
OAS: 
101112295(GNAQ)
SSC: 
654405(GNAQ)
CFR: 
102508547(GNAQ)
BACU: 
103018216(GNAQ)
LVE: 
103082420(GNAQ)
ECB: 
100063136(GNAQ)
MYB: 
102247263(GNAQ)
MYD: 
102760847(GNAQ)
PALE: 
102877919(GNAQ)
LAV: 
100656672(GNAQ)
MDO: 
100011605(GNAQ)
SHR: 
100916183(GNAQ)
OAA: 
GGA: 
427262(GNAQ)
CJO: 
107306232(GNAQ)
APLA: 
TGU: 
100230245(GNAQ)
GFR: 
FAB: 
101809288(GNAQ)
PHI: 
102103304(GNAQ)
CCW: 
104691989(GNAQ)
FPG: 
101912464(GNAQ)
FCH: 
102046812(GNAQ)
CLV: 
102093509(GNAQ)
AAM: 
ASN: 
102388376(GNAQ)
AMJ: 
102565550(GNAQ)
PSS: 
102454459(GNAQ)
CMY: 
102941281(GNAQ)
ACS: 
100565556(gnaq)
PBI: 
103054358(GNAQ)
GJA: 
XLA: 
394425(gnaq-a) 399261(gnaq-b)
XTR: 
733773(gnaq)
DRE: 
445232(gna15.1) 445297(gna14) 562625(gna15.4) 563953(gna11a) 570108(gnaq)
TRU: 
TNG: 
MZE: 
OLA: 
XMA: 
SASA: 
LCM: 
102352409(GNA11) 102359416(GNAQ)
CMK: 
CIN: 
445772(cigq)
SPU: 
404200(gnaq)
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD10904(Dsim_GD10904) Dsimw501_GD10905(Dsim_GD10905) Dsimw501_GD10906(Dsim_GD10906)
DWI: 
DYA: 
Dyak_GE12481(dyak_GLEANR_12731) Dyak_GE12482(dyak_GLEANR_12732) Dyak_GE12483(dyak_GLEANR_12733)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
BIM: 
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
BMOR: 
692442(Gq)
DPL: 
PXY: 
API: 
PHU: 
DPX: 
ISC: 
CEL: 
CELE_M01D7.7(egl-30)
CBR: 
CBG22211(Cbr-egl-30)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
SMM: 
Smp_005790(Smp_005790:mRNA:exon:7)
NVE: 
ADF: 
HMG: 
100192224(gnai3)
TAD: 
AQU: 
MBR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Milligan G, Kostenis E
  Title
Heterotrimeric G-proteins: a short history.
  Journal
Br J Pharmacol 147 Suppl 1:S46-55 (2006)
Reference
  Authors
Wettschureck N, Offermanns S.
  Title
Mammalian G proteins and their cell type specific functions.
  Journal
Physiol Rev 85:1159-204 (2005)
Reference
  Authors
Mizuno N, Itoh H
  Title
Functions and regulatory mechanisms of Gq-signaling pathways.
  Journal
Neurosignals 17:42-54 (2009)

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