KEGG   ORTHOLOGY: K04982
Entry
K04982                      KO                                     
Symbol
TRPM7, CHAK1
Name
transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
Pathway
map04217  Necroptosis
map04218  Cellular senescence
map04621  NOD-like receptor signaling pathway
map04978  Mineral absorption
Disease
H00058  Amyotrophic lateral sclerosis (ALS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
   04218 Cellular senescence
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
  09154 Digestive system
   04978 Mineral absorption
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  Alpha family [OT]
   K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
Other DBs
GO: 0005262
TC: 1.A.4.5.1
Genes
HSA: 54822(TRPM7)
PTR: 453429(TRPM7)
PPS: 100982703(TRPM7)
GGO: 101140728(TRPM7)
PON: 100437453(TRPM7)
NLE: 100587285(TRPM7)
HMH: 116481437(TRPM7)
MCC: 716755(TRPM7)
MCF: 102114767(TRPM7)
MTHB: 126958682
MNI: 105490436(TRPM7)
CSAB: 103245635(TRPM7)
CATY: 105588226(TRPM7)
TGE: 112627766(TRPM7)
MLEU: 105550751(TRPM7)
RRO: 104656904(TRPM7)
RBB: 108544826(TRPM7)
TFN: 117070667(TRPM7)
PTEH: 111552800(TRPM7)
CANG: 105502252(TRPM7)
CJC: 100401153(TRPM7)
SBQ: 101052786(TRPM7)
CIMI: 108295590(TRPM7)
CSYR: 103274326(TRPM7)
MMUR: 105870749(TRPM7)
LCAT: 123622635(TRPM7)
PCOQ: 105814519
OGA: 100949636(TRPM7)
MMU: 58800(Trpm7)
MCAL: 110289320(Trpm7)
MPAH: 110317831(Trpm7)
RNO: 679906(Trpm7)
MCOC: 116090864(Trpm7)
ANU: 117704059(Trpm7)
MUN: 110551943(Trpm7)
CGE: 100752689(Trpm7)
MAUA: 101844011(Trpm7)
PROB: 127221503(Trpm7)
PLEU: 114709085(Trpm7)
MORG: 121465872(Trpm7)
MFOT: 126494288
AAMP: 119815471(Trpm7)
NGI: 103733047(Trpm7)
HGL: 101709993(Trpm7)
CPOC: 100716553(Trpm7)
CCAN: 109699886(Trpm7)
DORD: 105981106(Trpm7)
DSP: 122114377(Trpm7)
PLOP: 125340670(Trpm7)
NCAR: 124978074
MMMA: 107138110(Trpm7)
OCU: 100350932
OPI: 101534277(TRPM7)
TUP: 102492170(TRPM7) 106733924
GVR: 103585833(TRPM7)
CFA: 478300(TRPM7)
CLUD: 112675941(TRPM7)
VVP: 112920061(TRPM7)
VLG: 121483258(TRPM7)
NPO: 129506251(TRPM7)
AML: 100482433(TRPM7)
UMR: 103676738(TRPM7)
UAH: 113269614(TRPM7)
UAR: 123801864(TRPM7)
ELK: 111158565
LLV: 125103869
MPUF: 101692155(TRPM7)
MNP: 131999752(TRPM7)
MLK: 131836277(TRPM7)
NVS: 122892881(TRPM7)
ORO: 101381534(TRPM7)
EJU: 114206358(TRPM7)
ZCA: 113908524(TRPM7)
MLX: 118003350(TRPM7)
NSU: 110583774(TRPM7)
LWW: 102749775(TRPM7)
FCA: 101095177(TRPM7)
PYU: 121041692(TRPM7)
PCOO: 112855585(TRPM7)
PBG: 122468653(TRPM7)
PVIV: 125167739(TRPM7)
LRUF: 124508593
PPAD: 109262997(TRPM7)
PUC: 125908841
AJU: 106967234
HHV: 120235011(TRPM7)
BTA: 514642(TRPM7)
BOM: 102278251(TRPM7)
BIU: 109565130(TRPM7)
BBUB: 102396769(TRPM7)
BBIS: 104988247(TRPM7)
CHX: 102173747(TRPM7)
OAS: 100037693(TRPM7)
BTAX: 128054812(TRPM7)
ODA: 120852978(TRPM7)
CCAD: 122443614(TRPM7)
MBEZ: 129563605(TRPM7)
SSC: 100169932(TRPM7)
CFR: 102518266(TRPM7)
CBAI: 105077020(TRPM7)
CDK: 105102459(TRPM7)
VPC: 102545569(TRPM7)
BACU: 103015250(TRPM7)
BMUS: 118889779(TRPM7)
LVE: 103082405(TRPM7)
OOR: 101284278(TRPM7)
DLE: 111181560(TRPM7)
PCAD: 102981704(TRPM7)
PSIU: 116748711(TRPM7)
NASI: 112411021(TRPM7)
ECB: 102149157(TRPM7)
EPZ: 103546934(TRPM7)
EAI: 106838402(TRPM7)
MYB: 102256071(TRPM7)
MYD: 102755894(TRPM7)
MMYO: 118651760(TRPM7)
MLF: 102423655(TRPM7)
PKL: 118721317(TRPM7)
EFUS: 103287424(TRPM7)
MNA: 107534881(TRPM7)
DRO: 112311670(TRPM7)
SHON: 118992620(TRPM7)
AJM: 119057606(TRPM7)
PDIC: 114491826(TRPM7)
PHAS: 123808893(TRPM7)
MMF: 118615557(TRPM7)
PPAM: 129064251(TRPM7)
HAI: 109394179(TRPM7)
RFQ: 117022976(TRPM7)
PALE: 102884616(TRPM7)
PGIG: 120623108(TRPM7)
PVP: 105288747(TRPM7)
RAY: 107501944(TRPM7)
MJV: 108391298(TRPM7)
TOD: 119238617(TRPM7)
SARA: 101552909(TRPM7)
SETR: 126019997(TRPM7)
LAV: 100672088(TRPM7)
TMU: 101349029
ETF: 101660894(TRPM7)
DNM: 101431060(TRPM7)
MDO: 100031256(TRPM7)
GAS: 123237945(TRPM7)
SHR: 100934039(TRPM7)
AFZ: 127551146
PCW: 110203550(TRPM7)
OAA: 100090926(TRPM7)
GGA: 427502(TRPM7)
PCOC: 116225332(TRPM7)
MGP: 100542333(TRPM7)
CJO: 107318704(TRPM7)
TPAI: 128075620(TRPM7)
LMUT: 125698431(TRPM7)
NMEL: 110403612(TRPM7)
APLA: 101796059(TRPM7)
ACYG: 106043381(TRPM7)
CATA: 118251976(TRPM7)
AFUL: 116493351(TRPM7)
TGU: 100228325(TRPM7)
LSR: 110474258(TRPM7)
SCAN: 103816033(TRPM7)
PMOA: 120508871(TRPM7)
OTC: 121343576(TRPM7)
PRUF: 121354307(TRPM7)
FAB: 101813566(TRPM7)
OMA: 130257531(TRPM7)
PHI: 102106298(TRPM7)
PMAJ: 107209240(TRPM7)
CCAE: 111933879(TRPM7)
CCW: 104683979(TRPM7)
CBRC: 103621331(TRPM7)
ETL: 114059935(TRPM7)
ZAB: 102069818(TRPM7)
SVG: 106860060(TRPM7)
MMEA: 130575788(TRPM7)
HRT: 120758977(TRPM7)
FCH: 114015105
CLV: 102086184(TRPM7)
EGZ: 104130794(TRPM7)
NNI: 104017260(TRPM7)
PCRI: 104033258(TRPM7)
PLET: 104626874(TRPM7)
PCAO: 104051668
ACUN: 113483902(TRPM7)
TALA: 104363978(TRPM7)
PADL: 103922740(TRPM7)
AFOR: 103896708(TRPM7)
ACHC: 115341546(TRPM7)
HALD: 104319415
HLE: 104834515(TRPM7)
AGEN: 126043720
GCL: 127020405
CCRI: 104167967(TRPM7)
MUI: 104545710(TRPM7)
MNB: 103777146(TRPM7)
OHA: 104334640(TRPM7)
NNT: 104404698(TRPM7)
SHAB: 115613092(TRPM7)
DPUB: 104297386(TRPM7)
PGUU: 104463981(TRPM7)
CPEA: 104386026(TRPM7)
AVIT: 104280110(TRPM7)
CVF: 104287460(TRPM7)
RTD: 128914579(TRPM7)
CUCA: 104055742(TRPM7)
TEO: 104372489(TRPM7)
BRHI: 104501210(TRPM7)
AAM: 106496405
AROW: 112963477(TRPM7)
NPD: 112952774(TRPM7)
TGT: 104567420(TRPM7)
DNE: 112996009(TRPM7)
ASN: 102372173(TRPM7)
AMJ: 102566660(TRPM7)
CPOO: 109309061(TRPM7)
GGN: 109288571(TRPM7)
PSS: 102461295
CMY: 102929346(TRPM7)
CCAY: 125643965(TRPM7)
DCC: 119862635(TRPM7)
CPIC: 101940689(TRPM7)
TST: 117883544(TRPM7)
CABI: 116830921(TRPM7)
MRV: 120373012(TRPM7)
ACS: 100559024(trpm7)
ASAO: 132762349(TRPM7)
PVT: 110077231(TRPM7)
SUND: 121933020(TRPM7)
PBI: 103065308(TRPM7)
PMUR: 107293588(TRPM7)
CTIG: 120315074(TRPM7)
TSR: 106546390(TRPM7)
PGUT: 117675751(TRPM7)
APRI: 131184791(TRPM7)
PTEX: 113442407(TRPM7)
NSS: 113418278(TRPM7)
VKO: 123027610(TRPM7)
PMUA: 114584753(TRPM7)
PRAF: 128401720(TRPM7)
ZVI: 118092703(TRPM7)
HCG: 128334957(TRPM7)
GJA: 107124454(TRPM7)
STOW: 125424531(TRPM7)
EMC: 129345178(TRPM7)
XLA: 108711406(trpm7.L) 108711407 108712895(trpm7.S)
XTR: 100329113(trpm7) 100497855
NPR: 108804799 108804815(TRPM7)
RTEM: 120931298(TRPM7) 120931300
BBUF: 120986468(TRPM7) 120986476
MUO: 115459808 115459809(TRPM7)
GSH: 117348175(TRPM7) 117348494
DRE: 280653(trpm7)
SRX: 107715248 107724022(trpm7)
SGH: 107569970(trpm7) 107595391
CCAR: 109044934(trpm7)
CAUA: 113061330 113118053(trpm7)
PTET: 122362711(trpm7)
LROH: 127157461(trpm7)
OMC: 131523998(trpm7)
PPRM: 120484842(trpm7)
RKG: 130077514(trpm7)
MAMB: 125254727(trpm7)
CIDE: 127499641
TROS: 130562609(trpm7)
TDW: 130435242(trpm7)
MANU: 129419217(trpm7)
IPU: 108264473
IFU: 128607136(trpm7)
PHYP: 113526647
TFD: 113638754(trpm7)
TVC: 132851518(trpm7)
AMEX: 111197571(trpm7)
CMAO: 118804019(trpm7)
EEE: 113585346(trpm7)
CHAR: 105889093(trpm7)
TRU: 101077272(trpm7)
TFS: 130519713(trpm7)
LCO: 104929767(trpm7)
NCC: 104946310
TBEN: 117471571(trpm7)
CGOB: 115024183(trpm7)
PGEO: 117440326(trpm7)
GACU: 117558967(trpm7)
EMAC: 134862894(trpm7)
ELY: 117249330(trpm7)
EFO: 125899705(trpm7)
PLEP: 121962486(trpm7)
ECRA: 117948287(trpm7)
ESP: 116677260
PFLV: 114560260(trpm7)
GAT: 120830706(trpm7)
PPUG: 119228338(trpm7)
AFB: 129107935(trpm7)
CLUM: 117748575(trpm7)
PSWI: 130192357(trpm7)
MSAM: 119890505(trpm7)
SCHU: 122878574(trpm7)
CUD: 121512176(trpm7)
MZE: 101479476(trpm7)
ONL: 109194405(trpm7)
OAU: 116322853(trpm7)
OLA: 101156483(trpm7)
OML: 112160646(trpm7)
CSAI: 133464448
XMA: 102224766(trpm7)
XCO: 114143366(trpm7)
XHE: 116719166(trpm7)
PRET: 103462173(trpm7)
PFOR: 103136025(trpm7)
PLAI: 106953770(trpm7)
PMEI: 106916683(trpm7)
GAF: 122819860(trpm7)
PPRL: 129369464(trpm7)
CVG: 107099438(trpm7)
CTUL: 119771633(trpm7)
GMU: 124866733(trpm7)
NFU: 107373599(trpm7)
KMR: 108237368(trpm7)
ALIM: 106518980(trpm7)
NWH: 119423403(trpm7)
AOCE: 111568465(trpm7)
MCEP: 125005128(trpm7)
CSEM: 103379369(trpm7)
POV: 109624842(trpm7)
SSEN: 122772175(trpm7)
HHIP: 117758188(trpm7)
HSP: 118105808(trpm7)
SMAU: 118302064(trpm7)
LCF: 108876909
SDU: 111218170(trpm7)
SLAL: 111659123(trpm7)
XGL: 120790858(trpm7)
HCQ: 109513898(trpm7)
SSCV: 125967520
SBIA: 133498092
PEE: 133397439
PTAO: 133474232
BPEC: 110175509(trpm7)
MALB: 109955892 109971580(trpm7)
BSPL: 114852630(trpm7)
SJO: 128359944(trpm7)
OTW: 112249377(trpm7)
OGO: 124033539(trpm7)
ONE: 115124851
OKE: 118375900(trpm7)
SALP: 112076906
CCLU: 121579911(trpm7)
ELS: 105022650(trpm7) 106024192
SFM: 108941140(trpm7) 108942028
PKI: 111845024(trpm7) 111846675
AANG: 118215450 118227349(trpm7)
LOC: 102682361(trpm7)
PSEX: 120541323(trpm7)
LCM: 102357315(TRPM7)
CMK: 103186533(trpm7)
CPLA: 122539582(trpm7)
HOC: 132834324(trpm7)
LERI: 129712684(trpm7)
PMRN: 116940949
LRJ: 133346765
BGT: 106074184
HRF: 124143875
MMER: 123546843
 » show all
Reference
  Authors
Schmitz C, Perraud AL, Johnson CO, Inabe K, Smith MK, Penner R, Kurosaki T, Fleig A, Scharenberg AM
  Title
Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7.
  Journal
Cell 114:191-200 (2003)
DOI:10.1016/S0092-8674(03)00556-7
Reference
  Authors
Nadler MJ, Hermosura MC, Inabe K, Perraud AL, Zhu Q, Stokes AJ, Kurosaki T, Kinet JP, Penner R, Scharenberg AM, Fleig A
  Title
LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability.
  Journal
Nature 411:590-5 (2001)
DOI:10.1038/35079092
  Sequence
[hsa:54822]

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