KEGG   ORTHOLOGY: K05406Help
Entry
K05406                      KO                                     

Name
IL12A
Definition
interleukin 12A
Pathway
Cytokine-cytokine receptor interaction
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Jak-STAT signaling pathway
Th1 and Th2 cell differentiation
Type I diabetes mellitus
Pertussis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Malaria
Toxoplasmosis
Amoebiasis
Tuberculosis
Measles
Influenza A
Herpes simplex infection
Pathways in cancer
Inflammatory bowel disease (IBD)
Allograft rejection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05406  IL12A; interleukin 12A
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05406  IL12A; interleukin 12A
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K05406  IL12A; interleukin 12A
   04622 RIG-I-like receptor signaling pathway
    K05406  IL12A; interleukin 12A
   04658 Th1 and Th2 cell differentiation
    K05406  IL12A; interleukin 12A
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05406  IL12A; interleukin 12A
  Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    K05406  IL12A; interleukin 12A
   05330 Allograft rejection
    K05406  IL12A; interleukin 12A
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K05406  IL12A; interleukin 12A
  Infectious diseases
   05133 Pertussis
    K05406  IL12A; interleukin 12A
   05134 Legionellosis
    K05406  IL12A; interleukin 12A
   05152 Tuberculosis
    K05406  IL12A; interleukin 12A
   05162 Measles
    K05406  IL12A; interleukin 12A
   05164 Influenza A
    K05406  IL12A; interleukin 12A
   05168 Herpes simplex infection
    K05406  IL12A; interleukin 12A
   05146 Amoebiasis
    K05406  IL12A; interleukin 12A
   05144 Malaria
    K05406  IL12A; interleukin 12A
   05145 Toxoplasmosis
    K05406  IL12A; interleukin 12A
   05140 Leishmaniasis
    K05406  IL12A; interleukin 12A
   05142 Chagas disease (American trypanosomiasis)
    K05406  IL12A; interleukin 12A
   05143 African trypanosomiasis
    K05406  IL12A; interleukin 12A
Cytokines [BR:ko04052]
 Class I cytokines (hematopoietin family)
  IL-6 receptor family
   K05406  IL12A; interleukin 12A
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Cytokines
   K05406  IL12A; interleukin 12A
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3592(IL12A)
PTR: 
460816(IL12A)
PPS: 
100979574(IL12A)
GGO: 
101150677(IL12A)
PON: 
100444807(IL12A)
NLE: 
100603245(IL12A)
MCC: 
703205(IL12A)
MCF: 
102115316(IL12A)
CSAB: 
103241402(IL12A)
RRO: 
104665012(IL12A)
RBB: 
108514790(IL12A)
CJC: 
100406669(IL12A)
SBQ: 
101044358(IL12A)
MMU: 
16159(Il12a)
RNO: 
84405(Il12a)
CGE: 
100760602(Il12a)
NGI: 
103745345(Il12a)
HGL: 
101701392(Il12a)
CCAN: 
109692199(Il12a)
OCU: 
100349007(IL12A)
TUP: 
102493627(IL12A)
CFA: 
403977(IL12A)
AML: 
100470471(IL12A)
UMR: 
103681335(IL12A)
FCA: 
493741(IL12A)
PTG: 
102971802(IL12A)
AJU: 
106969467(IL12A)
BTA: 
281856(IL12A)
BOM: 
102276398(IL12A)
BIU: 
109564477(IL12A)
PHD: 
102336917(IL12A)
CHX: 
100861293(IL12A)
OAS: 
443064(IL12A)
SSC: 
397053(IL12A)
CFR: 
102507202(IL12A)
CDK: 
105094260(IL12A)
BACU: 
103003516(IL12A)
LVE: 
103079299(IL12A)
ECB: 
100034215(IL12A)
EPZ: 
103562911(IL12A)
EAI: 
106824114(IL12A)
MYB: 
102251395(IL12A)
MYD: 
102753538(IL12A)
HAI: 
109373148(IL12A)
RSS: 
109447501(IL12A)
PALE: 
102887571(IL12A)
LAV: 
100665137(IL12A)
MDO: 
100018516(IL12A)
SHR: 
100914201(IL12A)
OAA: 
100086041(IL12A)
GGA: 
407090(IL12A)
MGP: 
100542954(IL12A)
CJO: 
107318422(IL12A)
APLA: 
101805034(IL12A)
ACYG: 
106043510(IL12A)
FAB: 
101809609(IL12A)
PMAJ: 
107199630(IL12A)
CCW: 
104688158(IL12A)
FPG: 
101915475(IL12A)
FCH: 
102047690(IL12A)
CLV: 
102091031(IL12A)
AAM: 
106495099(IL12A)
ASN: 
102368752(IL12A)
AMJ: 
102576541(IL12A)
PSS: 
102457029(IL12A)
CMY: 
102945506(IL12A)
CPIC: 
101945519(IL12A)
PVT: 
PBI: 
103063822(IL12A)
XTR: 
101734580(il12a)
DRE: 
100004358(zmp:0000001127) 445410(il12a)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
LCO: 
NCC: 
MZE: 
OLA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
CMK: 
103176349(il12a)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1673147
  Authors
Wolf SF, Temple PA, Kobayashi M, Young D, Dicig M, Lowe L, Dzialo R, Fitz L, Ferenz C, Hewick RM, et al.
  Title
Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells.
  Journal
J Immunol 146:3074-81 (1991)
  Sequence
[hsa:3592]
Reference
  Authors
Klinke DJ 2nd
  Title
A multiscale systems perspective on cancer, immunotherapy, and Interleukin-12.
  Journal
Mol Cancer 9:242 (2010)
DOI:10.1186/1476-4598-9-242

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