KEGG   ORTHOLOGY: K05414
Entry
K05414                      KO                                     
Symbol
IFNA
Name
interferon alpha
Pathway
map04060  Cytokine-cytokine receptor interaction
map04151  PI3K-Akt signaling pathway
map04217  Necroptosis
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04622  RIG-I-like receptor signaling pathway
map04623  Cytosolic DNA-sensing pathway
map04630  JAK-STAT signaling pathway
map04650  Natural killer cell mediated cytotoxicity
map04936  Alcoholic liver disease
map05152  Tuberculosis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05165  Human papillomavirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05320  Autoimmune thyroid disease
map05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05414  IFNA; interferon alpha
   04151 PI3K-Akt signaling pathway
    K05414  IFNA; interferon alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05414  IFNA; interferon alpha
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05414  IFNA; interferon alpha
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05414  IFNA; interferon alpha
   04621 NOD-like receptor signaling pathway
    K05414  IFNA; interferon alpha
   04622 RIG-I-like receptor signaling pathway
    K05414  IFNA; interferon alpha
   04623 Cytosolic DNA-sensing pathway
    K05414  IFNA; interferon alpha
   04650 Natural killer cell mediated cytotoxicity
    K05414  IFNA; interferon alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05414  IFNA; interferon alpha
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05414  IFNA; interferon alpha
   05161 Hepatitis B
    K05414  IFNA; interferon alpha
   05160 Hepatitis C
    K05414  IFNA; interferon alpha
   05171 Coronavirus disease - COVID-19
    K05414  IFNA; interferon alpha
   05164 Influenza A
    K05414  IFNA; interferon alpha
   05162 Measles
    K05414  IFNA; interferon alpha
   05168 Herpes simplex virus 1 infection
    K05414  IFNA; interferon alpha
   05163 Human cytomegalovirus infection
    K05414  IFNA; interferon alpha
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05414  IFNA; interferon alpha
   05169 Epstein-Barr virus infection
    K05414  IFNA; interferon alpha
   05165 Human papillomavirus infection
    K05414  IFNA; interferon alpha
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K05414  IFNA; interferon alpha
  09163 Immune disease
   05320 Autoimmune thyroid disease
    K05414  IFNA; interferon alpha
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K05414  IFNA; interferon alpha
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K05414  IFNA; interferon alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05414  IFNA; interferon alpha
Cytokines and neuropeptides [BR:ko04052]
 Cytokines
  Interferons
   K05414  IFNA; interferon alpha
Other DBs
GO: 0005132
Genes
HSA: 3439(IFNA1) 3440(IFNA2) 3441(IFNA4) 3442(IFNA5) 3443(IFNA6) 3444(IFNA7) 3445(IFNA8) 3446(IFNA10) 3447(IFNA13) 3448(IFNA14) 3449(IFNA16) 3451(IFNA17) 3452(IFNA21)
PTR: 473185(IFNA21) 473191 473193(IFNA14) 473195(IFNA5) 473196(IFNA6) 473197 473198(IFNA2) 473199(IFNA8) 741660 741747 741797 741978 742651 744748
PPS: 100967539 100968231 100968579 100968923 100969275 100969624 100970300 100970658 100971675(IFNA6) 100972005 100972354 100972691(IFNA8) 100973049 100995734 117981650 117981651 117981652 117981653
GGO: 101137870(IFNA21) 101138981 101139336 101139713 101140412 101141176(IFNA6) 101141543 101141916(IFNA2) 101142301(IFNA8) 101142673 115935827 115935828 115935829 115935831 115935832 115935833 115935834
PON: 100432153 100432532(IFNA8) 100432906(IFNA2) 100433301 100434036(IFNA6) 100434796 100435169 100437034 100438149 100438871 100439978(IFNA21) 100443523 100445711 100459543 112134962
NLE: 100594907 100595254(IFNA8) 100595585(IFNA2) 100595932 100596272(IFNA6) 100596946 100597288 100597620 100597957 100598307
HMH: 116458330 116458331 116458332 116458527 116458611 116458660
MCC: 106992322 106995851(IFNA6) 114672663 114672664 694631 709559(IFNA13) 709755(IFNA8) 709948(IFNA2) 710487 710528 710568 710654(IFNA10) 710751 710848 711088 711252(IFNA21)
MCF: 102115289 102140303 102140954(IFNA8) 102141352 102141744 102142148(IFNA2) 102143043(IFNA6) 102144479 102144833 102145208 102145962 102146344 102146717 102147079 123569038
MTHB: 126937598 126937600 126937601 126937602 126937603 126937604 126937605 126937606 126937607 126937608 126937609 126937610 126937611 126937612 126937613 126937615 126947451
PCOQ: 105827001
MMU: 15962(Ifna1) 15964(Ifna11) 15965(Ifna2) 15967(Ifna4) 15968(Ifna5) 15969(Ifna6) 15970(Ifna7) 15972(Ifna9) 15974(Ifnab) 230396(Ifna13) 230398(Ifna16) 242517(Ifna15) 242519(Ifna12) 404549(Ifna14)
RNO: 100911527(Ifna4l1) 100912314 100912356 134487075 134487077 298205(Ifna4) 298210(Ifna5) 298213(Ifna2) 500491(Ifna16l1) 502959(Ifna1l1) 502961(Ifna4l2) 690894(Ifna1)
HGL: 101697163
FCA: 101081371 101088440 111557596 493648(IFNA8) 493653(IFNA7) 493840(IFNA5)
PTG: 102956750
SSC: 100152100(IFN-ALPHA-13) 100152504(IFN-ALPHA-15) 100153325 100153661 100153724(IFN-ALPHA-8) 100154938(IFN-ALPHA-17) 100156561(IFN-ALPHA-10) 100156936 100157352(IFN-ALPHA-1) 100157735(IFN-ALPHA-16) 100157766(IFN-ALPHA-9) 100303758(IFN-ALPHA-5) 100310806(IFN-ALPHAOMEGA) 100737904 397686(IFNA1)
MYB: 106724769
MYD: 102766079
MMYO: 118667586
PPAM: 129078455
HAI: 109374670
TOD: 119232539
SARA: 101549593
SETR: 126003615 126003784(IFNA6)
ETF: 101650862
OAA: 100075323(IFN3)
GGA: 100857744(IFNAL4) 100857947(IFNAL5) 100858177 100859032(IFNAL6) 101750245(IFNKL1) 396398(IFNA3) 768614(IFA3L)
MGP: 104915046
CJO: 107306162
NMEL: 110390131
ACYG: 106044139
CATA: 118253811
AFUL: 116500557
LSR: 110470691
SCAN: 103819513 115485133(IFNK)
OTC: 121333061
PRUF: 121363354
FAB: 101811547(IFNW1) 101815751
OMA: 130265253
PMAJ: 107215808
CCW: 104685212
CBRC: 103613130
ACHL: 103797348
SVG: 106863721
MMEA: 130573232
HRT: 120765752
FPG: 101915699(IFNW1)
FCH: 102059593 114016448(IFNK)
CLV: 102092004
PCRI: 104033504
PLET: 104614046
EHS: 104517087
PCAO: 104039528
ACUN: 113490068 113490202(IFNK)
TALA: 104368839
AFOR: 103894835
ACHC: 115336480
AGEN: 126036597
GCL: 127027653
CCRI: 104154797
CSTI: 104555774
CMAC: 104478818
GSTE: 104255408
MNB: 103774794
NNT: 104411022
SHAB: 115600831(IFNK) 115619639
DPUB: 104305721
ACAR: 104527107
AVIT: 104269528
RTD: 128902910
CUCA: 104063167
TEO: 104369870
TGT: 104573472 104578601(IFNA7)
SCAM: 104145483(IFNB1) 104147423
PMUR: 107293819
CTIG: 120314223
TSR: 106542110
PMUA: 114588052(IFNK)
GJA: 107108155
MUO: 115481865
DRE: 100126803(ifnphi3) 360134(ifnphi1)
PTET: 122341354(ifnphi3) 122341864(ifnphi1)
OMC: 131537137(ifnphi1) 131537782(ifnphi3)
PPRM: 120490098(ifnphi3) 120490237(ifnphi1)
RKG: 130070297(ifnphi1) 130070313(ifnphi3)
MAMB: 125250057(ifnphi3) 125268605 125272663(ifnphi1)
TROS: 130561720(ifnphi1) 130561905(ifnphi3)
TDW: 130425819(ifnphi1) 130426410(ifnphi3)
MANU: 129423862(ifnphi3) 129436390(ifnphi1) 129436392
EMAC: 134870800 134871102 134878662(ifnphi1)
ECRA: 117936743(ifnphi4) 117940493
ESP: 116670973
PPUG: 119212932 119212933 119220758(ifnphi1)
CLUM: 117734698(ifnphi1) 117748853 117748885(ifnphi4)
SCHU: 122867615 122867624 122869125(ifnphi1)
PRET: 108167267
CVG: 107092889
ALIM: 106535558
NWH: 119423813
POV: 109642673
HHIP: 117752524 117752526(ifnphi4) 117758149 117766140(ifnphi1)
SLAL: 111656186
SBIA: 133495998(ifnphi4) 133514304(ifnphi1)
PEE: 133414847(ifnphi1)
PTAO: 133466487(ifnphi1) 133469710(ifnphi4)
BPEC: 110154330
BSPL: 114846466
HOC: 132830747(ifnphi4) 132830748
 » show all
Reference
PMID:6157600
  Authors
Mantei N, Schwarzstein M, Streuli M, Panem S, Nagata S, Weissmann C
  Title
The nucleotide sequence of a cloned human leukocyte interferon cDNA.
  Journal
Gene 10:1-10 (1980)
DOI:10.1016/0378-1119(80)90137-7
  Sequence
[hsa:3439]

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