KEGG ORTHOLOGY: K05415

ORTHOLOGY: K05415

Entry

K05415                      KO

Symbol

IFNB

Name

interferon beta

Pathway

map04060

Cytokine-cytokine receptor interaction

map04151

PI3K-Akt signaling pathway

map04217

Necroptosis

map04380

Osteoclast differentiation

map04620

Toll-like receptor signaling pathway

map04621

NOD-like receptor signaling pathway

map04622

RIG-I-like receptor signaling pathway

map04623

Cytosolic DNA-sensing pathway

map04630

JAK-STAT signaling pathway

map04650

Natural killer cell mediated cytotoxicity

map04668

TNF signaling pathway

map04936

Alcoholic liver disease

map05131

Shigellosis

map05135

Yersinia infection

map05142

Chagas disease

map05152

Tuberculosis

map05160

Hepatitis C

map05161

Hepatitis B

map05162

Measles

map05163

Human cytomegalovirus infection

map05164

Influenza A

map05165

Human papillomavirus infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05168

Herpes simplex virus 1 infection

map05169

Epstein-Barr virus infection

map05170

Human immunodeficiency virus 1 infection

map05171

Coronavirus disease - COVID-19

map05417

Lipid and atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05415  IFNB; interferon beta
   04668 TNF signaling pathway
    K05415  IFNB; interferon beta
   04151 PI3K-Akt signaling pathway
    K05415  IFNB; interferon beta
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05415  IFNB; interferon beta
09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05415  IFNB; interferon beta
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04621 NOD-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04622 RIG-I-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04623 Cytosolic DNA-sensing pathway
    K05415  IFNB; interferon beta
   04650 Natural killer cell mediated cytotoxicity
    K05415  IFNB; interferon beta
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05415  IFNB; interferon beta
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05415  IFNB; interferon beta
   05161 Hepatitis B
    K05415  IFNB; interferon beta
   05160 Hepatitis C
    K05415  IFNB; interferon beta
   05171 Coronavirus disease - COVID-19
    K05415  IFNB; interferon beta
   05164 Influenza A
    K05415  IFNB; interferon beta
   05162 Measles
    K05415  IFNB; interferon beta
   05168 Herpes simplex virus 1 infection
    K05415  IFNB; interferon beta
   05163 Human cytomegalovirus infection
    K05415  IFNB; interferon beta
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05415  IFNB; interferon beta
   05169 Epstein-Barr virus infection
    K05415  IFNB; interferon beta
   05165 Human papillomavirus infection
    K05415  IFNB; interferon beta
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K05415  IFNB; interferon beta
   05135 Yersinia infection
    K05415  IFNB; interferon beta
   05152 Tuberculosis
    K05415  IFNB; interferon beta
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K05415  IFNB; interferon beta
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K05415  IFNB; interferon beta
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K05415  IFNB; interferon beta
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05415  IFNB; interferon beta
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  Interferons
   K05415  IFNB; interferon beta

Other DBs

GO:

0005132

Genes

HSA:	3456(IFNB1)

PTR:	473183(IFNB1)

PPS:	100995851(IFNB1)

GGO:	101137136(IFNB1)

PON:	100441074(IFNB1)

NLE:	100598986(IFNB1)

HMH:	116458843(IFNB1)

MCC:	711414(IFNB1)

MCF:	102115670(IFNB1)

MTHB:

126937702

MNI:	105465886(IFNB1)

CSAB:

103219383(IFNB1)

CATY:

105584002(IFNB1)

PANU:

101024523(IFNB1)

TGE:	112608413(IFNB1)

MLEU:

105545746(IFNB1)

RRO:	104670295(IFNB1)

RBB:	108538565(IFNB1)

TFN:	117098642(IFNB1)

PTEH:

111526147(IFNB1)

CANG:

105503452(IFNB1)

CJC:	100388391(IFNB1)

SBQ:	101035681(IFNB1)

CIMI:

108296169(IFNB1)

CSYR:

103260915(IFNB1)

MMUR:

105874210(IFNB1)

LCAT:

123646249(IFNB1)

PCOQ:

105827006(IFNB1)

OGA:	100959385(IFNB1)

MMU:	15977(Ifnb1)

MCAL:

110293791(Ifnb1)

MPAH:

110323346(Ifnb1)

RNO:	24481(Ifnb1)

MCOC:

116095400(Ifnb1)

ANU:	117709633(Ifnb1)

MUN:	110541303(Ifnb1)

CGE:	103160615(Ifnb1)

MAUA:

121144026(Ifnb1)

PROB:

127224840(Ifnb1)

PLEU:

114685139(Ifnb1)

MORG:

121447990(Ifnb1)

MFOT:

126510741

AAMP:

119816165(Ifnb1) 119817276

NGI:	103743951(Ifnb1) 103746144

HGL:	101699042(Ifnb1) 101723869

CPOC:

100733284 100734449 111757491(Ifnb1)

DORD:

105988975(Ifnb1)

DSP:	122118962(Ifnb1)

PLOP:

125352673(Ifnb1)

NCAR:

124963924 124963958 124964114 124964969 124965019

MMMA:

107156465 107156489(Ifnb1)

OCU:

100342931

OPI:	101533318(IFNB1)

TUP:	102493858(IFNB1)

GVR:	103584029 103609847 103609850

CFA:	481558(IFNB1)

CLUD:

112650215(IFNB1)

VVP:	112921940(IFNB1)

VLG:	121494639(IFNB1)

NPO:	129494739(IFNB1)

AML:	100476556(IFNB1)

UMR:	103662150(IFNB1)

UAH:	113260295(IFNB1)

UAR:	123781031(IFNB1)

ELK:

111156577

LLV:

125083789

MPUF:

101679100(IFNB1)

MNP:	132025125(IFNB1)

MLK:	131813182(IFNB1)

NVS:	122916938(IFNB1)

ORO:	101374900(IFNB1)

EJU:	114212404(IFNB1)

ZCA:	113934419(IFNB1)

MLX:	117998994(IFNB1)

NSU:	110587130(IFNB1)

LWW:	102748842(IFNB1)

FCA:	493849(IFNB1)

PYU:

121034394

PCOO:

112849621(IFNB1)

PBG:	122474874(IFNB1)

PVIV:

125150775

LRUF:

124525672

PTG:	102960421(IFNB1)

PPAD:

109247124(IFNB1)

PUC:

125925944

AJU:

106971145

HHV:	120239877(IFNB1)

BTA:	100848709 112441471 112441480 112447877 112447878 112447879 112447880 281845(IFNB1) 517016 525550 616977 618946(IFNB3) 784525

BOM:	102280497 102281065 102282466 102284581

BIU:	109562667 109562671 109562674 109562675 109562852 109562853 109562855

BBUB:

102402056 102402367 102402697 102408434 112583883 112583884 112583885 112583886 123332785 123465588 123465589

BBIS:

104983695 104996149 105000961(IFNB1) 105000962 105000963

CHX:	102181595 102181867 102189208 108633243 108636544 108636629 108636632 108636634

OAS:	101103376 101103623 101103702 114112819 114112830 114112835 114112840 114112883 114113004 114113016 114113206 121818657

BTAX:

128052625 128052626 128052627 128052628 128052635 128052636 128052637 128052638 128052639 128052640 128052652

ODA:	120860069 120860132 120860137 120862218 120862226 120862257

CCAD:

122453394 122453395 122453396 122453397 122453398 122453400

MBEZ:

129557110 129557288 129557307 129557308

SSC:	445459(IFNB1)

CFR:	102513411(IFNB1)

CBAI:

105061881(IFNB1)

CDK:	105095933(IFNB1)

VPC:	102540243(IFNB1)

BACU:

103011926

BMUS:

118897323(IFNB1)

LVE:

103073772

OOR:	101289058(IFNB1)

DLE:	111174560(IFNB1)

PCAD:

102990155(IFNB1)

PSIU:

116755914(IFNB1)

NASI:

112407026(IFNB1)

ECB:	100052545(IFNB1) 100052658 100147174

EPZ:	103563147 103563148 103563150

EAI:	106828272 106834164 106834179 106834202 123280255 123280293

MYB:	102261905(IFNB1)

MYD:	102765800(IFNB1)

MMYO:

118666805(IFNB1)

MLF:	102417209(IFNB1)

PKL:	118716770(IFNB1)

EFUS:

103289195(IFNB1)

MNA:	107531433(IFNB1)

DRO:	112300024(IFNB1)

SHON:

118997987 118997988 118997989 118997990

AJM:	119055662(IFNB1)

PDIC:

114512515(IFNB1)

PHAS:

123820149 123820232(IFNB1)

MMF:	118629329(IFNB1)

PPAM:

129078454(IFNB1)

HAI:	109396418(IFNB1)

RFQ:	117032413(IFNB1)

PALE:

102890512(IFNB1)

PGIG:

120605473(IFNB1)

PVP:	105309141(IFNB1)

RAY:	107518589(IFNB1)

MJV:	108402531(IFNB1)

TOD:	119231101(IFNB1)

SARA:

101548268(IFNB1)

SETR:

126002675(IFNB1)

LAV:	100666438(IFNB1)

TMU:

101349610

ETF:	101650550(IFNB1)

DNM:	101410923(IFNB1)

MDO:	100021258(IFNB1)

GAS:

123250431

SHR:

100914443

AFZ:

127552925

PCW:	110199211 110199212 110199213 110199216 110199218

OAA:	100082925(IFNB1)

GGA:	554219(IFNW1)

MGP:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

106045178 125180135 125180136

CATA:

118257698 118257699 118257700 118257701 118257702 118257703 118257704 126913675 126913676

AFUL:

116500389 116500390 116500391 116500392 116501035

LSR:

SCAN:

OTC:

PRUF:

OMA:	130265549 130265550

CBRC:

ZAB:

ACHL:

SVG:

MMEA:

HRT:	120765091 120765092 120765093 120765094 120765095

FPG:

NNI:

EHS:

PCAO:

TALA:

AFOR:

ACHC:

115337094 115337096 115337097

HLE:

104827847

GCL:	127027303 127027304 127027305 127027306

CMAC:

MUI:

FGA:

LDI:

MNB:

NNT:

SHAB:

115619468 115619469 115619470 115619471

ACAR:

CPEA:

CVF:

RTD:

CUCA:

AROW:

SCAM:

TVC:

Reference

PMID:16593086

Authors

Ohno S, Taniguchi T

Title

Structure of a chromosomal gene for human interferon beta.

Journal

Proc Natl Acad Sci U S A 78:5305-9 (1981)
DOI:10.1073/pnas.78.9.5305

Sequence

[hsa:3456]

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (56)   
   KEGG PATHWAY (56)   
Drug (1)   
   KEGG DRUG (1)   
Gene (352)   
   KEGG GENES (351)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (413)   

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