KEGG   ORTHOLOGY: K05434Help
Entry
K05434                      KO                                     

Name
IL21
Definition
interleukin 21
Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Inflammatory bowel disease (IBD)
Disease
H00408  
Type I diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05434  IL21; interleukin 21
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05434  IL21; interleukin 21
 Human Diseases
  Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    K05434  IL21; interleukin 21
Cytokines [BR:ko04052]
 Class I cytokines (hematopoietin family)
  IL-2 receptor family
   K05434  IL21; interleukin 21
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
59067(IL21)
PTR: 
471295(IL21)
PPS: 
100984436(IL21)
GGO: 
101133146(IL21)
PON: 
100455621(IL21)
NLE: 
100591664(IL21)
MCC: 
708125(IL21)
MCF: 
102130762(IL21)
CSAB: 
103236210(IL21)
RRO: 
104661749(IL21)
CJC: 
100386141(IL21)
SBQ: 
101029390(IL21)
MMU: 
60505(Il21)
RNO: 
365769(Il21)
CGE: 
100755479(Il21)
NGI: 
103746950(Il21)
HGL: 
101720915(Il21)
OCU: 
100344172(IL21)
TUP: 
102478178(IL21)
CFA: 
442935(IL21)
AML: 
100480614(IL21)
UMR: 
103661805(IL21)
FCA: 
101087399(IL21)
PTG: 
102956388(IL21)
BTA: 
378475(IL21)
BOM: 
102285740(IL21)
PHD: 
102321488(IL21)
CHX: 
100861248(IL21)
OAS: 
100862657(IL21)
SSC: 
403123(IL21)
CFR: 
102515160(IL21)
BACU: 
103017608(IL21)
LVE: 
ECB: 
100063803(IL21)
MYB: 
102261365(IL21)
MYD: 
102763101(IL21)
PALE: 
102895772(IL21)
LAV: 
100656684(IL21)
SHR: 
105751011(IL21)
GGA: 
554218(IL21)
MGP: 
100550694(IL21)
CJO: 
107313576(IL21)
APLA: 
101794729(IL21)
TGU: 
100223945(IL21)
GFR: 
102035531(IL21)
FAB: 
101807374(IL21)
CCW: 
104693711(IL21)
CLV: 
102091768(IL21)
AAM: 
106491934(IL21)
XTR: 
100145684(il21)
DRE: 
100150203(il21)
TRU: 
654314(il-21)
MZE: 
OLA: 
100169843(il-21)
SASA: 
106604597(IL21A) 106611666(il21)
LCM: 
102365373(IL21)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA, Johnston J, Madden K, Xu W, West J, Schrader S, Burkhead S, Heipel M, Brandt C, Kuijper JL, Kramer J, Conklin D, Presnell SR, Berry J, Shiota F, Bort S, Hambly K, Mudri S, Clegg C, Moore M, Grant FJ, Lofton-Day C, Gilbert T, Rayond F, Ching A, Yao L, Smith D, Webster P, Whitmore T, Maurer M, Kaushansky K, Holly RD, Foster D
  Title
Interleukin 21 and its receptor are involved in NK cell expansion and regulation  of lymphocyte function.
  Journal
Nature 408:57-63 (2000)
  Sequence
[hsa:59067]

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