KEGG ORTHOLOGY: K05468

ORTHOLOGY: K05468

Entry

K05468                      KO

Symbol

LTA, TNFB

Name

lymphotoxin alpha (TNF superfamily, member 1)

Pathway

map04060

Cytokine-cytokine receptor interaction

map04061

Viral protein interaction with cytokine and cytokine receptor

map04064

NF-kappa B signaling pathway

map04668

TNF signaling pathway

map04940

Type I diabetes mellitus

map05166

Human T-cell leukemia virus 1 infection

map05168

Herpes simplex virus 1 infection

Disease

H00344

Leprosy

H01730

Myocardial infarction

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
   04668 TNF signaling pathway
    K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
   05168 Herpes simplex virus 1 infection
    K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  Tumor necrosis fators
   K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)

Other DBs

GO:

0005164

Genes

HSA:

4049(LTA)

PTR:	494185(LTA)

PPS:	100979816(LTA)

GGO:

101150218

PON:	100446211(LTA)

NLE:	100581070(LTA)

HMH:	116460113(LTA)

MCC:	715425(LTA)

MCF:	102138497(LTA)

MTHB:

126953146

MNI:	105497641(LTA)

CATY:

105573464(LTA)

TGE:	112623174(LTA)

MLEU:

105554158(LTA)

RRO:	104661912(LTA)

RBB:	108520256(LTA)

TFN:	117086927(LTA)

PTEH:

111523941(LTA)

CANG:

105513727(LTA)

CJC:	100397110(LTA)

SBQ:	101032617(LTA)

CIMI:

108299859(LTA)

CSYR:

103270148(LTA)

MMUR:

105858138(LTA)

LCAT:

123631723(LTA)

PCOQ:

105817906(LTA)

OGA:	100963296(LTA)

MMU:	16992(Lta)

MCAL:

110284314(Lta)

MPAH:

110335951(Lta)

RNO:	25008(Lta)

MCOC:

116074778(Lta)

ANU:	117724852(Lta)

CGE:	100765068(Lta)

MAUA:

101843451(Lta)

PROB:

127223874(Lta)

PLEU:

114705803(Lta)

MORG:

121435321(Lta)

MFOT:

126494878

AAMP:

119822513(Lta)

NGI:	103724453(Lta) 108490383

HGL:	101718783(Lta)

CPOC:

100722832(Lta)

CCAN:

109690395(Lta)

DORD:

105997012(Lta)

DSP:	122111282(Lta)

PLOP:

125353519(Lta)

NCAR:

124989577

MMMA:

107144045(Lta)

OCU:	100328931(LTA)

OPI:	101525798(LTA)

TUP:	102497568(LTA)

GVR:	103592384(LTA)

CFA:	607183(LTA)

CLUD:

112641288(LTA)

VVP:	112913802(LTA)

VLG:	121484710(LTA)

NPO:	129512469(LTA)

AML:	100471816(LTA)

UMR:	103682323(LTA)

UAH:	113243662(LTA)

UAR:	123791077(LTA)

ELK:

111152291

LLV:

125103143

MPUF:

101687624(LTA)

MNP:	132017782(LTA)

MLK:	131834373(LTA)

NVS:	122899956(LTA)

ORO:	101367910(LTA)

EJU:	114222243(LTA)

ZCA:	113927753(LTA)

MLX:	118027256(LTA)

NSU:	110586793(LTA)

LWW:	102743202(LTA)

FCA:	101084961(LTA)

PYU:	121022313(LTA)

PCOO:

112853730(LTA)

PBG:	122478259(LTA)

PVIV:

125165328(LTA)

LRUF:

124528592

PTG:	102959201(LTA)

PPAD:

109260533(LTA)

PUC:

125938465

AJU:

106983956

HHV:	120221914(LTA)

BTA:	280845(LTA)

BOM:	102277623(LTA)

BIU:	109577429(LTA)

BBUB:

102391778(LTA)

BBIS:

104983773(LTA)

CHX:	102180548(LTA)

OAS:	101123078(LTA)

BTAX:

128056921(LTA)

ODA:	120870535(LTA)

CCAD:

122430073(LTA)

MBEZ:

129543582(LTA)

SSC:	407742(LTA)

CFR:	102510664(LTA)

CBAI:

105074075(LTA)

CDK:	105087474(LTA)

VPC:	102541673(LTA)

BACU:

103006180(LTA)

BMUS:

118903923(LTA)

LVE:	103083505(LTA)

OOR:	101270123(LTA)

DLE:	111170658(LTA)

PCAD:

102983830(LTA)

PSIU:

116762490(LTA)

NASI:

112395424(LTA)

ECB:	100058321(LTA)

EPZ:	103562471(LTA)

EAI:	106825036(LTA)

MYB:	102247784(LTA)

MYD:	102770131(LTA)

MLF:	111822966(LTA)

PKL:	118716991(LTA)

EFUS:

103300479(LTA)

MNA:	107539004(LTA)

DRO:	112302069(LTA)

SHON:

118987587(LTA)

AJM:	119053713(LTA)

PDIC:

114494459(LTA)

PHAS:

123810385(LTA)

MMF:	118621917(LTA)

PPAM:

129067304(LTA)

HAI:	109373061(LTA)

RFQ:	117020878(LTA)

PALE:

102887880(LTA)

PGIG:

120618947(LTA)

PVP:	105305326(LTA)

RAY:	107498474(LTA)

MJV:	108397878(LTA)

TOD:	119253236(LTA)

SARA:

101547466(LTA)

SETR:

125996224(LTA)

LAV:	100677409(LTA)

TMU:

101342393

ETF:	101654325(LTA)

DNM:	101420892(LTA)

MDO:	100023043(LTA)

GAS:	123245102(LTA)

SHR:	100921616(LTA)

AFZ:

127561060

PCW:	110199296(LTA)

OAA:	114808152(LTA)

PSS:	106732346(LTA)

CMY:	102936098(LTA)

CCAY:

125621406

DCC:

119842670

CPIC:

101949323(LTA)

CABI:

116822864

MRV:	120392345(LTA)

XLA:	108698566(lta.L) 108700671(lta.S)

XTR:	100135001(lta)

NPR:

108793733

RTEM:

120914517(LTA)

BBUF:

120977833

BGAR:

122919609

MUO:	115464340 115464887

GSH:	117346331 117350071

DRE:	554167(tnfb)

SRX:	107730828 107752817

SANH:

107683455 107704715

SGH:	107576541 107582292

CCAR:

109099637 109106190

CAUA:

113058615 113058937 113114983

CGIB:

127972179 128028603

PTET:

122358407(tnfb)

LROH:

127176864(tnfb)

OMC:	131520521(tnfb)

PPRM:

120477521(tnfb)

RKG:	130104303(tnfb)

MAMB:

125248153(tnfb)

CIDE:

127495475

MASI:

127422051 127430184

TROS:

130564920 130564947(tnfb)

TDW:	130428850 130428874

MANU:

129437370(tnfb)

IPU:	108277448(tnfb)

IFU:	128621327(tnfb)

SMEO:

124394736(tnfb)

TFD:	113642755(tnfb)

TVC:	132857932(tnfb)

CMAO:

118796723(tnfb)

EEE:

113583403

TFS:	130533177(tnfb)

TBEN:

117468516(tnfb)

CGOB:

115021209

PGEO:

117461058(tnfb)

GACU:

117543265(tnfb)

EMAC:

134861362(tnfb)

EFO:	125892700(tnfb)

PLEP:

121945792(tnfb)

SLUC:

116060006(tnfb)

ECRA:

117946791(tnfb)

ESP:

PFLV:

GAT:

PPUG:

AFB:	129109266(tnfb)

CLUM:

117728316(tnfb)

PSWI:

130187969(tnfb)

SCHU:

122881722(tnfb)

CUD:	121513655(tnfb)

ALAT:

119005615(tnfb) 119030139 119030560

OLA:

101159531

OML:	112136647(tnfb)

CSAI:

133441129

XMA:

102225449

XCO:

114139432

XHE:	116716995 116723775

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122831869(tnfb)

PPRL:

129353553 129379972(tnfb)

CVG:

107104043

CTUL:

119796531(tnfb)

GMU:	124865917(tnfb)

NFU:	107383266 107396784

ALIM:

106531681

NWH:	119409830(tnfb)

MCEP:

125015835(tnfB)

SSEN:

122774338(tnfb)

HHIP:

117776201(tnfb)

HSP:	118113802(tnfb)

SMAU:

118306893(tnfb)

SSCV:

125975249

SBIA:

133500889(tnfb)

PEE:	133402142(tnfb)

PTAO:

133479494(tnfb)

MALB:

109974577

BSPL:

114842561(tnfb)

SJO:	128366508(tnfb)

STRU:

OGO:

ONE:

OKI:

OKE:

SNH:

ELS:

SFM:

PKI:	111842756 111849861

AANG:

118224026(tnfb) 118233140(tnfa)

LOC:

102691380

ARUT:

117971660

LCM:	102360515(TNFSF15)

CPLA:

122546262

LERI:

129694587 129694588

GAE:	121369287 121372958 121373244 121373281 121373282 121373399 121373748 121386091

HRF:	124118679 124122759

HRJ:	124262446 124268579

MYI:

RPHI:

ATEN:

Reference

PMID:3536896

Authors

Kobayashi Y, Miyamoto D, Asada M, Obinata M, Osawa T

Title

Cloning and expression of human lymphotoxin mRNA derived from a human T cell hybridoma.

Journal

J Biochem 100:727-33 (1986)
DOI:10.1093/oxfordjournals.jbchem.a121765

Sequence

[hsa:4049]

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (14)   
   KEGG PATHWAY (14)   
Disease (2)   
   KEGG DISEASE (2)   
Drug (3)   
   KEGG DRUG (3)   
Gene (313)   
   KEGG GENES (290)   
   KEGG MGENES (16)   
   RefGene (4)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (336)   

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