KEGG   ORTHOLOGY: K05611Help
Entry
K05611                      KO                                     

Name
UCHL1
Definition
ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
Pathway
Parkinson's disease
Disease
H00057  
Parkinson's disease (PD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Human Diseases
  Neurodegenerative diseases
   05012 Parkinson's disease
    K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C12: ubiquitin C-terminal hydrolase family
   K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1
Ubiquitin system [BR:ko04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UCH
    K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1
BRITE hierarchy
Genes
HSA: 
7345(UCHL1)
PTR: 
461185(UCHL1)
PPS: 
100978798(UCHL1)
GGO: 
101150793(UCHL1)
PON: 
100440914(UCHL1)
NLE: 
100588568(UCHL1)
MCC: 
MCF: 
102133043(UCHL1)
CJC: 
100409098(UCHL1)
MMU: 
22223(Uchl1)
RNO: 
29545(Uchl1)
CGE: 
100766373(Uchl1)
HGL: 
101702892(Uchl1)
TUP: 
102478017(UCHL1)
CFA: 
479098(UCHL1)
AML: 
UMR: 
103672780(UCHL1)
FCA: 
101093604(UCHL1)
PTG: 
102949487(UCHL1)
BTA: 
514394(UCHL1)
BOM: 
102282378(UCHL1)
PHD: 
102325635(UCHL1)
CHX: 
102178714(UCHL1)
OAS: 
101117250(UCHL1)
SSC: 
396637(UCHL1)
CFR: 
102514352(UCHL1)
BACU: 
103007566(UCHL1)
LVE: 
103069363(UCHL1)
ECB: 
100033838(UCHL1)
MYB: 
102262310(UCHL1)
MYD: 
102769091(UCHL1)
PALE: 
102881932(UCHL1)
MDO: 
100015629(UCHL1)
SHR: 
100918150(UCHL1)
GGA: 
770302(UCHL1)
MGP: 
APLA: 
101799480(UCHL1)
TGU: 
751589(UCHL1)
FAB: 
101809666(UCHL1)
PHI: 
102104928(UCHL1)
FPG: 
101924718(UCHL1)
FCH: 
102047483(UCHL1)
CLV: 
102083724(UCHL1)
ASN: 
AMJ: 
102576186(UCHL1)
PSS: 
102451446(UCHL1)
CMY: 
102945907(UCHL1)
ACS: 
100561831(uchl1)
PBI: 
103058291(UCHL1)
XLA: 
735204(uchl1)
XTR: 
496780(uchl1)
DRE: 
325119(uchl1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102365585(UCHL1)
CMK: 
103175870(uchl1)
CPV: 
CHO: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Liu Y, Fallon L, Lashuel HA, Liu Z, Lansbury PT Jr
  Title
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.
  Journal
Cell 111:209-18 (2002)
  Sequence
[hsa:7345]

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