KEGG   ORTHOLOGY: K05630Help
Entry
K05630                      KO                                     

Name
WWP2, AIP2
Definition
atrophin-1 interacting protein 2 (WW domain containing E3 ubiquitin protein ligase 2) [EC:2.3.2.26]
Pathway
Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K05630  WWP2, AIP2; atrophin-1 interacting protein 2 (WW domain containing E3 ubiquitin protein ligase 2)
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     K05630  WWP2, AIP2; atrophin-1 interacting protein 2 (WW domain containing E3 ubiquitin protein ligase 2)
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  HECT type E3
   K05630  WWP2, AIP2; atrophin-1 interacting protein 2 (WW domain containing E3 ubiquitin protein ligase 2)
BRITE hierarchy
Genes
HSA: 
11060(WWP2)
PTR: 
743862(WWP2)
PPS: 
100973972(WWP2)
GGO: 
PON: 
100438429(WWP2)
NLE: 
100604312(WWP2)
MCC: 
705464(WWP2)
MCF: 
102123009(WWP2)
RRO: 
104655882(WWP2)
CJC: 
100405825(WWP2)
MMU: 
66894(Wwp2)
RNO: 
291999(Wwp2)
CGE: 
100761484(Wwp2)
NGI: 
103734667(Wwp2)
HGL: 
101710527(Wwp2)
OCU: 
100344222(WWP2)
TUP: 
102494947(WWP2)
CFA: 
479672(WWP2)
AML: 
100474146(WWP2)
UMR: 
103673607(WWP2)
FCA: 
101098349(WWP2)
PTG: 
102956978(WWP2)
BTA: 
512457(WWP2)
BOM: 
102280579(WWP2)
PHD: 
CHX: 
102174504(WWP2)
OAS: 
101122376(WWP2)
SSC: 
100626361(WWP2)
CFR: 
102513891(WWP2)
BACU: 
103005821(WWP2)
LVE: 
103068585(WWP2)
ECB: 
100067291(WWP2)
MYB: 
102263170(WWP2)
MYD: 
102764062(WWP2)
PALE: 
102889650(WWP2)
MDO: 
100020484(WWP2)
SHR: 
100917130(WWP2)
OAA: 
100077057(WWP2)
GGA: 
415868(WWP2)
MGP: 
CJO: 
107319450(WWP2)
APLA: 
101801353(WWP2)
TGU: 
100230386(WWP2)
GFR: 
102041977(WWP2)
FAB: 
101820426(WWP2)
PHI: 
102113277(WWP2)
CCW: 
104691954(WWP2)
FPG: 
101912384(WWP2)
FCH: 
CLV: 
102094230(WWP2)
AAM: 
106498549(WWP2)
ASN: 
102371401(WWP2)
AMJ: 
102562530(WWP2)
PSS: 
CMY: 
102930866(WWP2)
ACS: 
100561726(wwp2)
PBI: 
103053726(WWP2)
GJA: 
107106534(WWP2)
XTR: 
100038252(wwp2)
DRE: 
564527(wwp2)
TRU: 
101068381(wwp2)
MZE: 
101472498(wwp2)
OLA: 
101168206(wwp2)
XMA: 
102222753(wwp2)
LCM: 
102355333(WWP2)
CMK: 
103175970(wwp2)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Chen A, Gao B, Zhang J, McEwen T, Ye SQ, Zhang D, Fang D
  Title
The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T-cell death by catalyzing EGR2 ubiquitination.
  Journal
Mol Cell Biol 29:5348-56 (2009)
  Sequence
[hsa:11060] [mmu:66894]
Reference
  Authors
Xu H, Wang W, Li C, Yu H, Yang A, Wang B, Jin Y
  Title
WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells.
  Journal
Cell Res 19:561-73 (2009)
  Sequence
[hsa:11060]

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