KEGG   ORTHOLOGY: K05636Help
Entry
K05636                      KO                                     

Name
LAMB1
Definition
laminin, beta 1
Pathway
ko04151  PI3K-Akt signaling pathway
ko04510  Focal adhesion
ko04512  ECM-receptor interaction
ko05145  Toxoplasmosis
ko05146  Amoebiasis
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05222  Small cell lung cancer
Disease
H00268  Lissencephaly (LIS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K05636  LAMB1; laminin, beta 1
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K05636  LAMB1; laminin, beta 1
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K05636  LAMB1; laminin, beta 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05636  LAMB1; laminin, beta 1
   05222 Small cell lung cancer
    K05636  LAMB1; laminin, beta 1
  Infectious diseases
   05165 Human papillomavirus infection
    K05636  LAMB1; laminin, beta 1
   05146 Amoebiasis
    K05636  LAMB1; laminin, beta 1
   05145 Toxoplasmosis
    K05636  LAMB1; laminin, beta 1
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Neural system
   Enzymatic CD
    PTPRF, LAR; receptor-type tyrosine-protein phosphatase F
     Laminin-1
      K05636 LAMB1; laminin, beta 1
  Others
   LU; Lutheran blood group glycoprotein
    Laminin-10
     K05636 LAMB1; laminin, beta 1
   MCAM, CD146; melanoma cell adhesion molecule
    Laminin-8
     K05636 LAMB1; laminin, beta 1
   CXADR, CAR; coxsackievirus and adenovirus receptor
    Laminin-1
     K05636 LAMB1; laminin, beta 1
 2. Integrin Family
  Beta1 integrins
   VLA-1
    ITGB1; integrin beta 1
     Laminin-1
      K05636 LAMB1; laminin, beta 1
     Laminin-2
      K05636 LAMB1; laminin, beta 1
   VLA-2
    ITGB1; integrin beta 1
     Laminin-1
      K05636 LAMB1; laminin, beta 1
     Laminin-2
      K05636 LAMB1; laminin, beta 1
   VLA-3
    ITGB1; integrin beta 1
     Laminin-2
      K05636 LAMB1; laminin, beta 1
     Laminin-10
      K05636 LAMB1; laminin, beta 1
   VLA-6
    ITGB1; integrin beta 1
     Laminin-1
      K05636 LAMB1; laminin, beta 1
     Laminin-2
      K05636 LAMB1; laminin, beta 1
     Laminin-8
      K05636 LAMB1; laminin, beta 1
     Laminin-10
      K05636 LAMB1; laminin, beta 1
   VLA-7
    ITGB1; integrin beta 1
     Laminin-1
      K05636 LAMB1; laminin, beta 1
     Laminin-2
      K05636 LAMB1; laminin, beta 1
  Beta4 integrins
   alpha 6 beta 4
    ITGB4; integrin beta 4
     Laminin-1
      K05636 LAMB1; laminin, beta 1
     Laminin-2
      K05636 LAMB1; laminin, beta 1
 7. Others
  DAG1; dystroglycan 1
   Laminin-1
    K05636 LAMB1; laminin, beta 1
   Laminin-2
    K05636 LAMB1; laminin, beta 1
  APP; amyloid beta A4 protein
   Laminin-1
    K05636 LAMB1; laminin, beta 1
BRITE hierarchy
Genes
HSA: 3912(LAMB1)
PTR: 463656(LAMB1)
PPS: 100994583(LAMB1)
GGO: 101134136(LAMB1)
PON: 100458670(LAMB1)
NLE: 100581721(LAMB1)
MCC: 702111(LAMB1)
MCF: 102126233(LAMB1)
CSAB: 103226726(LAMB1)
RRO: 104677415(LAMB1)
RBB: 108540465(LAMB1)
CJC: 100400907(LAMB1)
SBQ: 101045731(LAMB1)
MMU: 16777(Lamb1)
RNO: 298941(Lamb1)
CGE: 100757343(Lamb1)
NGI: 103732168(Lamb1)
HGL: 101700233(Lamb1)
CCAN: 109690109(Lamb1) 109690112
OCU: 100358679(LAMB1)
TUP: 102469659(LAMB1)
CFA: 475882(LAMB1)
AML: 100472572(LAMB1)
UMR: 103674704(LAMB1) 103675101
ORO: 101382657(LAMB1)
FCA: 101080367(LAMB1)
PTG: 102954545 102962439(LAMB1)
AJU: 106980652(LAMB1)
BTA: 520030(LAMB1)
BOM: 102278503(LAMB1)
BIU: 109557393(LAMB1)
PHD: 102337582(LAMB1)
CHX: 102176661(LAMB1)
OAS: 101105743(LAMB1)
SSC: 396707(LAMB1)
CFR: 102521906(LAMB1)
CDK: 105093058(LAMB1)
BACU: 102997450(LAMB1)
LVE: 103071744(LAMB1)
OOR: 101278853(LAMB1)
ECB: 100060360(LAMB1)
EPZ: 103567994(LAMB1)
EAI: 106825193(LAMB1)
MYB: 102250973(LAMB1) 102263034
MYD: 102774918(LAMB1)
HAI: 109372668(LAMB1)
RSS: 109454582(LAMB1)
PALE: 102881611(LAMB1)
LAV: 100675837(LAMB1)
TMU: 101351432
MDO: 100010605(LAMB1)
SHR: 100929086(LAMB1)
GGA: 396478(LAMB1)
MGP: 100548782(LAMB1)
CJO: 107307972(LAMB1)
APLA: 101801494(LAMB1)
ACYG: 106042002(LAMB1)
TGU: 100222516(LAMB1)
GFR: 102035516(LAMB1)
FAB: 101809033(LAMB1)
PHI: 102104811(LAMB1)
PMAJ: 107204235(LAMB1)
CCW: 104686917(LAMB1)
FPG: 101913281(LAMB1)
FCH: 102053954(LAMB1)
CLV: 102091353(LAMB1)
EGZ: 104123792(LAMB1)
AAM: 106487735(LAMB1)
ASN: 102384699(LAMB1)
AMJ: 102568782(LAMB1)
PSS: 102458826(LAMB1)
CMY: 102929487(LAMB1)
CPIC: 101942545(LAMB1)
ACS: 100555341(lamb1)
PVT: 110070347(LAMB1)
PBI: 103059637(LAMB1)
GJA: 107119904(LAMB1)
XLA: 108711179(lamb1.L) 108713081(lamb1.S)
XTR: 100495516(lamb1)
NPR: 108802662(LAMB1)
DRE: 286830(lamb1a)
IPU: 108275309(lamb1) 108276201(lamb2) 108279853
TRU: 101062763(lamb1) 101075179
LCO: 104929904 104933728(lamb1)
NCC: 104941784(lamb1)
OLA: 101165682 101167953(lamb1)
XMA: 102229311(lamb1) 102232124
NFU: 107387385 107389091(lamb1)
CSEM: 103379635(lamb1) 103382600
BPEC: 110161568 110163781(lamb1)
ELS: 105007961 105018083(lamb1)
LCM: 102357660(LAMB1) 102358482
CIN: 100179911(lamb1)
SPU: 582206(lamb1)
DME: Dmel_CG7123(LanB1)
DSI: Dsimw501_GD23490(Dsim_GD23490)
MDE: 101887411
AAG: 5578743
AME: 726736(LanB1)
BIM: 100746803
BTER: 100642555
SOC: 105197652
AEC: 105152359
ACEP: 105626418
HST: 105180834
CFO: 105250996
LHU: 105667788
NVI: 100123956
TCA: 661297
DPA: 109537961
BMOR: 100862837(LanB1-w) 692392
PMAC: 106708834
PRAP: 110992852
API: 100159769
ZNE: 110833184
FCD: 110856721
CEL: CELE_W03F8.5(lam-1)
CBR: CBG20003(Cbr-lam-1)
BMY: Bm1_01080
TSP: Tsp_02564
OBI: 106877208
SHX: MS3_08997
EPA: 110253703
HMG: 100197276(lamb1)
AQU: 105314164
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3611077
  Authors
Pikkarainen T, Eddy R, Fukushima Y, Byers M, Shows T, Pihlajaniemi T, Saraste M, Tryggvason K
  Title
Human laminin B1 chain. A multidomain protein with gene (LAMB1) locus in the q22 region of chromosome 7.
  Journal
J Biol Chem 262:10454-62 (1987)
  Sequence
[hsa:3912]
Reference
  Authors
Durbeej M
  Title
Laminins.
  Journal
Cell Tissue Res 339:259-68 (2010)
DOI:10.1007/s00441-009-0838-2

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