KEGG   ORTHOLOGY: K05697Help
Entry
K05697                      KO                                     

Name
PTPN6, SHP-1
Definition
tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Pathway
Adherens junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Leishmaniasis
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6
 Cellular Processes
  Cell communication
   04520 Adherens junction
    K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6
   04660 T cell receptor signaling pathway
    K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6
   04662 B cell receptor signaling pathway
    K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6
  Infectious diseases
   05140 Leishmaniasis
    K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5777(PTPN6)
PTR: 
748032(PTPN6)
PPS: 
100990286(PTPN6)
GGO: 
101137792(PTPN6)
PON: 
100448471(PTPN6)
MCC: 
714374(PTPN6)
MCF: 
102133910(PTPN6)
MMU: 
15170(Ptpn6)
RNO: 
116689(Ptpn6)
CGE: 
100758996(Ptpn6)
HGL: 
101725029(Ptpn6)
TUP: 
102488290(PTPN6)
CFA: 
486717(PTPN6)
AML: 
100473539(PTPN6)
FCA: 
101087073(PTPN6)
PTG: 
102951517(PTPN6)
BTA: 
512312(PTPN6)
BOM: 
102283821(PTPN6)
PHD: 
102324934(PTPN6)
CHX: 
102190308(PTPN6)
SSC: 
100171389(PTPN6)
CFR: 
102513195(PTPN6)
ECB: 
100052882(PTPN6)
MYB: 
102256821(PTPN6)
MYD: 
102755999(PTPN6)
PALE: 
102895931(PTPN6)
MDO: 
100016514(PTPN6)
SHR: 
100916661(PTPN6)
OAA: 
100089663(PTPN6)
GGA: 
427947(PTPN6)
MGP: 
100541130(PTPN6)
TGU: 
100222135(PTPN6)
FAB: 
101809704(PTPN6)
PHI: 
102110203(PTPN6)
APLA: 
101791271(PTPN6)
FPG: 
101914570(PTPN6)
FCH: 
102049222(PTPN6)
CLV: 
102092597(PTPN6)
ASN: 
102374529(PTPN6)
PSS: 
102450493(PTPN6)
CMY: 
102932473(PTPN6)
ACS: 
XLA: 
100380954(ptpn6)
XTR: 
100144699(ptpn6)
DRE: 
335573(ptpn6)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Keilhack H, Muller M, Bohmer SA, Frank C, Weidner KM, Birchmeier W, Ligensa T, Berndt A, Kosmehl H, Gunther B, Muller T, Birchmeier C, Bohmer FD
  Title
Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.
  Journal
J Cell Biol 152:325-34 (2001)

DBGET integrated database retrieval system