KEGG   ORTHOLOGY: K05719Help
Entry
K05719                      KO                                     

Name
ITGB1, CD29
Definition
integrin beta 1
Pathway
ko04015  Rap1 signaling pathway
ko04145  Phagosome
ko04151  PI3K-Akt signaling pathway
ko04360  Axon guidance
ko04510  Focal adhesion
ko04512  ECM-receptor interaction
ko04514  Cell adhesion molecules (CAMs)
ko04530  Tight junction
ko04611  Platelet activation
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko05100  Bacterial invasion of epithelial cells
ko05130  Pathogenic Escherichia coli infection
ko05131  Shigellosis
ko05133  Pertussis
ko05140  Leishmaniasis
ko05145  Toxoplasmosis
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05222  Small cell lung cancer
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K05719  ITGB1, CD29; integrin beta 1
   04151 PI3K-Akt signaling pathway
    K05719  ITGB1, CD29; integrin beta 1
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K05719  ITGB1, CD29; integrin beta 1
   04514 Cell adhesion molecules (CAMs)
    K05719  ITGB1, CD29; integrin beta 1
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K05719  ITGB1, CD29; integrin beta 1
  Cellular community - eukaryotes
   04510 Focal adhesion
    K05719  ITGB1, CD29; integrin beta 1
   04530 Tight junction
    K05719  ITGB1, CD29; integrin beta 1
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05719  ITGB1, CD29; integrin beta 1
 Organismal Systems
  Immune system
   04611 Platelet activation
    K05719  ITGB1, CD29; integrin beta 1
   04670 Leukocyte transendothelial migration
    K05719  ITGB1, CD29; integrin beta 1
  Development
   04360 Axon guidance
    K05719  ITGB1, CD29; integrin beta 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05719  ITGB1, CD29; integrin beta 1
   05205 Proteoglycans in cancer
    K05719  ITGB1, CD29; integrin beta 1
   05222 Small cell lung cancer
    K05719  ITGB1, CD29; integrin beta 1
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K05719  ITGB1, CD29; integrin beta 1
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K05719  ITGB1, CD29; integrin beta 1
   05414 Dilated cardiomyopathy (DCM)
    K05719  ITGB1, CD29; integrin beta 1
  Infectious diseases
   05130 Pathogenic Escherichia coli infection
    K05719  ITGB1, CD29; integrin beta 1
   05131 Shigellosis
    K05719  ITGB1, CD29; integrin beta 1
   05133 Pertussis
    K05719  ITGB1, CD29; integrin beta 1
   05100 Bacterial invasion of epithelial cells
    K05719  ITGB1, CD29; integrin beta 1
   05165 Human papillomavirus infection
    K05719  ITGB1, CD29; integrin beta 1
   05145 Toxoplasmosis
    K05719  ITGB1, CD29; integrin beta 1
   05140 Leishmaniasis
    K05719  ITGB1, CD29; integrin beta 1
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    K05719  ITGB1, CD29; integrin beta 1
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K05719  ITGB1, CD29; integrin beta 1
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Neural system
   6/5 subfamily
    NRCAM; neuronal cell adhesion molecule
     VLA-4
      K05719 ITGB1, CD29; integrin beta 1
    L1CAM; L1 cell adhesion molecule
     VLA-5
      K05719 ITGB1, CD29; integrin beta 1
  Others
   VCAM1; vascular cell adhesion molecule 1
    VLA-4
     K05719 ITGB1, CD29; integrin beta 1
    VLA-9
     K05719 ITGB1, CD29; integrin beta 1
   ICAM4; intercellular adhesion molecule 4
    alpha V beta 1
     K05719 ITGB1, CD29; integrin beta 1
   LU; Lutheran blood group glycoprotein
    VLA-4
     K05719 ITGB1, CD29; integrin beta 1
   JAM2; junctional adhesion molecule 2
    VLA-4
     K05719 ITGB1, CD29; integrin beta 1
 2. Integrin Family
  Beta1 integrins
   VLA-2
    ITGB1; integrin beta 1
     VLA-3
      K05719 ITGB1, CD29; integrin beta 1
   VLA-3
    ITGB1; integrin beta 1
     VLA-2
      K05719 ITGB1, CD29; integrin beta 1
     VLA-3
      K05719 ITGB1, CD29; integrin beta 1
 5. Cadherin Family
  Classic Cadherins
   Vertebrate Type I classic cadherins
    CDHE, CDH1; cadherin 1, type 1, E-cadherin
     VLA-2
      K05719 ITGB1, CD29; integrin beta 1
  Clustered protocadherin
   PCDHA; protocadherin alpha
    VLA-5
     K05719 ITGB1, CD29; integrin beta 1
 7. Others
  TNFSF5, CD40L; tumor necrosis factor (ligand) superfamily, member 5
   VLA-5
    K05719 ITGB1, CD29; integrin beta 1
  SDC1; syndecan 1
   VLA-5
    K05719 ITGB1, CD29; integrin beta 1
  SDC4; syndecan 4
   VLA-5
    K05719 ITGB1, CD29; integrin beta 1
CD molecules [BR:ko04090]
 Proteins
  K05719  CD29, ITGB1; integrin, beta 1
BRITE hierarchy
Genes
HSA: 3688(ITGB1)
PTR: 450396(ITGB1)
PPS: 100992059(ITGB1)
GGO: 101142683(ITGB1)
PON: 100172223(ITGB1)
NLE: 100595108(ITGB1)
MCC: 574312(ITGB1)
MCF: 102144610(ITGB1)
CSAB: 103238098(ITGB1)
RRO: 104663301(ITGB1)
RBB: 108529400(ITGB1)
CJC: 100394145(ITGB1)
SBQ: 101040620(ITGB1)
MMU: 16412(Itgb1)
RNO: 24511(Itgb1)
CGE: 100763033(Itgb1)
NGI: 103745645(Itgb1)
HGL: 101711253(Itgb1)
CCAN: 109674981 109697920(Itgb1)
OCU: 100008898(ITGB1)
TUP: 102489284(ITGB1)
CFA: 477956(ITGB1)
AML: 100482697(ITGB1)
UMR: 103656511(ITGB1)
ORO: 101385291(ITGB1)
FCA: 751821(ITGB1)
PTG: 102967350(ITGB1)
AJU: 106967340(ITGB1)
BTA: 281876(ITGB1)
BOM: 102273972(ITGB1)
BIU: 109567924(ITGB1)
PHD: 102315653(ITGB1)
CHX: 102178060(ITGB1)
OAS: 443141(ITGB1)
SSC: 397019(ITGB1)
CFR: 102509512(ITGB1)
CDK: 105100650(ITGB1)
BACU: 103008019(ITGB1)
LVE: 103070821(ITGB1)
OOR: 101283510(ITGB1)
ECB: 100055024(ITGB1)
EPZ: 103565316(ITGB1)
EAI: 106836617(ITGB1)
MYB: 102260978(ITGB1)
MYD: 102757018(ITGB1)
HAI: 109388160(ITGB1)
RSS: 109452639(ITGB1)
PALE: 102886785(ITGB1)
LAV: 100664978(ITGB1)
TMU: 101360881
MDO: 100018342(ITGB1)
SHR: 100913968(ITGB1)
OAA: 100073959(ITGB1)
GGA: 374058(ITGB1)
MGP: 100551464(ITGB1)
CJO: 107308921(ITGB1)
APLA: 101792849(ITGB1)
ACYG: 106029652 106042674(ITGB1)
TGU: 100230947(ITGB1)
GFR: 102039987(ITGB1)
FAB: 101810282(ITGB1)
PHI: 102112472(ITGB1)
PMAJ: 107200467(ITGB1)
CCW: 104686529(ITGB1)
FPG: 101917395(ITGB1)
FCH: 102059641(ITGB1)
CLV: 102089491(ITGB1)
EGZ: 104133604(ITGB1)
AAM: 106489947(ITGB1)
ASN: 102383871(ITGB1)
AMJ: 102575802(ITGB1)
PSS: 102452555(ITGB1)
CMY: 102946836(ITGB1)
CPIC: 101948025(ITGB1)
ACS: 100562954(itgb1)
PVT: 110082773(ITGB1)
PBI: 103060558(ITGB1)
GJA: 107125566(ITGB1)
XLA: 397755(itgb1.L) 399443(itgb1.S)
XTR: 394767(itgb1)
NPR: 108792462(ITGB1)
DRE: 405864(itgb1b.2) 556734(itgb1a) 570216(itgb1b)
IPU: 100304492(itgb1) 108271845(itgb1)
NCC: 104959197 104965598(itgb1)
OLA: 101154978 101175441(itgb1)
BPEC: 110165515(itgb1) 110174882
LCM: 102348482(ITGB1) 102349081
CIN: 100181753
SKO: 102802131
DME: Dmel_CG1560(mys) Dmel_CG1762(Itgbn)
DSI: Dsimw501_GD16875(Dsim_GD16875) Dsimw501_GD28212(Dsim_GD28212)
AME: 100576742 406097(GB19541) 724950(GB12005)
DNX: 107165598
CEL: CELE_ZK1058.2(pat-3)
CBR: CBG03601(Cbr-pat-3)
BMY: Bm1_20780
SHX: MS3_05634
HMG: 100205067
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2958481
  Authors
Argraves WS, Suzuki S, Arai H, Thompson K, Pierschbacher MD, Ruoslahti E
  Title
Amino acid sequence of the human fibronectin receptor.
  Journal
J Cell Biol 105:1183-90 (1987)
DOI:10.1083/jcb.105.3.1183
  Sequence
[hsa:3688]
Reference
PMID:7523423
  Authors
Balzac F, Retta SF, Albini A, Melchiorri A, Koteliansky VE, Geuna M, Silengo L, Tarone G
  Title
Expression of beta 1B integrin isoform in CHO cells results in a dominant negative effect on cell adhesion and motility.
  Journal
J Cell Biol 127:557-65 (1994)
DOI:10.1083/jcb.127.2.557

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