KEGG   ORTHOLOGY: K05719Help
Entry
K05719                      KO                                     

Name
ITGB1
Definition
integrin beta 1
Pathway
Rap1 signaling pathway
Phagosome
PI3K-Akt signaling pathway
Axon guidance
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Platelet activation
Leukocyte transendothelial migration
Regulation of actin cytoskeleton
Bacterial invasion of epithelial cells
Pathogenic Escherichia coli infection
Shigellosis
Pertussis
Leishmaniasis
Toxoplasmosis
Pathways in cancer
Proteoglycans in cancer
Small cell lung cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K05719  ITGB1; integrin beta 1
   04151 PI3K-Akt signaling pathway
    K05719  ITGB1; integrin beta 1
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K05719  ITGB1; integrin beta 1
   04514 Cell adhesion molecules (CAMs)
    K05719  ITGB1; integrin beta 1
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K05719  ITGB1; integrin beta 1
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05719  ITGB1; integrin beta 1
  Cellular commiunity
   04510 Focal adhesion
    K05719  ITGB1; integrin beta 1
 Organismal Systems
  Immune system
   04611 Platelet activation
    K05719  ITGB1; integrin beta 1
   04670 Leukocyte transendothelial migration
    K05719  ITGB1; integrin beta 1
  Development
   04360 Axon guidance
    K05719  ITGB1; integrin beta 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05719  ITGB1; integrin beta 1
   05205 Proteoglycans in cancer
    K05719  ITGB1; integrin beta 1
   05222 Small cell lung cancer
    K05719  ITGB1; integrin beta 1
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K05719  ITGB1; integrin beta 1
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K05719  ITGB1; integrin beta 1
   05414 Dilated cardiomyopathy (DCM)
    K05719  ITGB1; integrin beta 1
  Infectious diseases
   05130 Pathogenic Escherichia coli infection
    K05719  ITGB1; integrin beta 1
   05131 Shigellosis
    K05719  ITGB1; integrin beta 1
   05133 Pertussis
    K05719  ITGB1; integrin beta 1
   05100 Bacterial invasion of epithelial cells
    K05719  ITGB1; integrin beta 1
   05145 Toxoplasmosis
    K05719  ITGB1; integrin beta 1
   05140 Leishmaniasis
    K05719  ITGB1; integrin beta 1
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K05719  ITGB1; integrin beta 1
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Neural system
   6/5 subfamily
    NRCAM; neuronal cell adhesion molecule
     VLA-4
      K05719 ITGB1; integrin beta 1
    L1CAM; L1 cell adhesion molecule
     VLA-5
      K05719 ITGB1; integrin beta 1
  Others
   VCAM1; vascular cell adhesion molecule 1
    VLA-4
     K05719 ITGB1; integrin beta 1
    VLA-9
     K05719 ITGB1; integrin beta 1
   ICAM4; intercellular adhesion molecule 4
    alpha V beta 1
     K05719 ITGB1; integrin beta 1
   LU; Lutheran blood group glycoprotein
    VLA-4
     K05719 ITGB1; integrin beta 1
   JAM2; junctional adhesion molecule 2
    VLA-4
     K05719 ITGB1; integrin beta 1
 2. Integrin Family
  Beta1 integrins
   VLA-2
    ITGB1; integrin beta 1
     VLA-3
      K05719 ITGB1; integrin beta 1
   VLA-3
    ITGB1; integrin beta 1
     VLA-2
      K05719 ITGB1; integrin beta 1
     VLA-3
      K05719 ITGB1; integrin beta 1
 5. Cadherin Family
  Classic Cadherins
   Vertebrate Type I classic cadherins
    CDHE, CDH1; cadherin 1, type 1, E-cadherin
     VLA-2
      K05719 ITGB1; integrin beta 1
  Clustered protocadherin
   PCDHA; protocadherin alpha
    VLA-5
     K05719 ITGB1; integrin beta 1
 7. Others
  TNFSF5, CD40L; tumor necrosis factor (ligand) superfamily, member 5
   VLA-5
    K05719 ITGB1; integrin beta 1
  SDC1; syndecan 1
   VLA-5
    K05719 ITGB1; integrin beta 1
  SDC4; syndecan 4
   VLA-5
    K05719 ITGB1; integrin beta 1
Cellular antigens [BR:ko04090]
 Proteins
  K05719  CD29, ITGB1; integrin, beta 1
BRITE hierarchy
Genes
HSA: 
3688(ITGB1)
PTR: 
450396(ITGB1)
PPS: 
100992059(ITGB1)
GGO: 
101142683(ITGB1)
PON: 
100172223(ITGB1)
MCC: 
574312(ITGB1)
MCF: 
102144610(ITGB1)
MMU: 
16412(Itgb1)
RNO: 
24511(Itgb1)
CGE: 
100763033(Itgb1)
HGL: 
101711253(Itgb1)
TUP: 
102489284(ITGB1)
CFA: 
477956(ITGB1)
AML: 
FCA: 
751821(ITGB1)
PTG: 
102967350(ITGB1)
BTA: 
281876(ITGB1)
BOM: 
102273972(ITGB1)
PHD: 
102315653(ITGB1)
CHX: 
102178060(ITGB1)
SSC: 
397019(ITGB1)
CFR: 
BACU: 
103008019(ITGB1)
LVE: 
103070821(ITGB1)
ECB: 
100055024(ITGB1)
MYB: 
102260978(ITGB1)
MYD: 
PALE: 
MDO: 
100018342(ITGB1)
SHR: 
100913968(ITGB1)
OAA: 
100073959(ITGB1)
GGA: 
374058(ITGB1)
MGP: 
TGU: 
100230947(ITGB1)
FAB: 
101810282(ITGB1)
PHI: 
102112472(ITGB1)
APLA: 
FPG: 
101917395(ITGB1)
FCH: 
102059641(ITGB1)
CLV: 
102089491(ITGB1)
ASN: 
102383871(ITGB1)
AMJ: 
PSS: 
102452555(ITGB1)
CMY: 
102946836(ITGB1)
ACS: 
PBI: 
XLA: 
397755(itgb1-a) 399443(itgb1-b)
XTR: 
394767(itgb1)
DRE: 
405864(itgb1b.2) 556734(itgb1a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
406097(GB19541) 724950(GB12005)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG03601(Cbr-pat-3)
BMY: 
LOA: 
TSP: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
van der Flier A, Sonnenberg A.
  Title
Function and interactions of integrins.
  Journal
Cell Tissue Res 305:285-98 (2001)
Reference
  Authors
Barczyk M, Carracedo S, Gullberg D
  Title
Integrins.
  Journal
Cell Tissue Res 339:269-80 (2010)

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