KEGG   ORTHOLOGY: K05730Help
Entry
K05730                      KO                                     

Name
VAV
Definition
guanine nucleotide exchange factor VAV
Pathway
cAMP signaling pathway
Chemokine signaling pathway
Focal adhesion
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04024 cAMP signaling pathway
    K05730  VAV; guanine nucleotide exchange factor VAV
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05730  VAV; guanine nucleotide exchange factor VAV
  Cellular commiunity
   04510 Focal adhesion
    K05730  VAV; guanine nucleotide exchange factor VAV
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05730  VAV; guanine nucleotide exchange factor VAV
   04660 T cell receptor signaling pathway
    K05730  VAV; guanine nucleotide exchange factor VAV
   04662 B cell receptor signaling pathway
    K05730  VAV; guanine nucleotide exchange factor VAV
   04664 Fc epsilon RI signaling pathway
    K05730  VAV; guanine nucleotide exchange factor VAV
   04666 Fc gamma R-mediated phagocytosis
    K05730  VAV; guanine nucleotide exchange factor VAV
   04670 Leukocyte transendothelial migration
    K05730  VAV; guanine nucleotide exchange factor VAV
   04062 Chemokine signaling pathway
    K05730  VAV; guanine nucleotide exchange factor VAV
BRITE hierarchy
Genes
HSA: 
10451(VAV3) 7409(VAV1) 7410(VAV2)
PTR: 
455647(VAV1) 457076(VAV3) 473114(VAV2)
PPS: 
100971161(VAV2) 100982766(VAV1) 100989733(VAV3)
GGO: 
101124128(VAV2) 101139851(VAV3) 101142265(VAV1)
PON: 
100171723(VAV2) 100442703(VAV3) 100447155(VAV1)
NLE: 
100582219(VAV2) 100599935(VAV3) 100600253(VAV1)
MCC: 
100424246(VAV1) 694685(VAV3) 713227(VAV2)
MCF: 
CJC: 
100388432(VAV1) 100390165(VAV3) 100406408(VAV2)
MMU: 
22324(Vav1) 22325(Vav2) 57257(Vav3)
RNO: 
25156(Vav1) 295378(Vav3) 296603(Vav2)
CGE: 
100759294(Vav2) 100765426(Vav1) 100768658(Vav3)
NGI: 
HGL: 
101700388(Vav1) 101716743(Vav3) 101721831(Vav2)
OCU: 
100341627(VAV3) 100348718(VAV1)
TUP: 
102467864(VAV2) 102485614(VAV1) 102488378(VAV3)
CFA: 
479921(VAV3) 485016(VAV1) 608060(VAV2)
AML: 
UMR: 
103675192(VAV3) 103679942(VAV2) 103681714(VAV1)
FCA: 
101086264(VAV2) 101087417(VAV3) 101097212(VAV1)
PTG: 
102955544(VAV3) 102959251(VAV2) 102967454(VAV1)
BTA: 
515718(VAV2) 521961(VAV3) 617345(VAV1)
BOM: 
102271877(VAV1) 102281896(VAV3) 102288386(VAV2)
PHD: 
102322124(VAV3) 102331440(VAV2) 102343860(VAV1)
CHX: 
OAS: 
101107354(VAV1) 101110137(VAV2) 101120709(VAV3)
SSC: 
100151826(VAV3) 100151931(VAV2) 100519821(VAV1) 100737105(VAV3)
CFR: 
102509705(VAV2) 102511438(VAV1) 102518740(VAV3)
BACU: 
103002083(VAV2) 103018979(VAV1) 103019070(VAV3)
LVE: 
103082841(VAV2) 103084985(VAV1) 103088874(VAV3)
ECB: 
100057737(VAV3) 100066010(VAV1) 100069175(VAV2)
MYB: 
102242321(VAV3) 102253658(VAV1) 102263523(VAV2)
MYD: 
102758091(VAV3) 102759764(VAV1) 102763071(VAV2)
PALE: 
102883521(VAV1) 102884766(VAV2) 102886772(VAV3)
MDO: 
100015350(VAV2) 100020150(VAV1) 100029844(VAV3)
SHR: 
100919264(VAV3) 100926184(VAV2) 100933888(VAV1)
OAA: 
100073433(VAV2) 100075831(VAV3) 100085604(VAV1)
GGA: 
373938(VAV2) 373939(VAV3)
MGP: 
APLA: 
101793733(VAV3) 101802656(VAV2)
TGU: 
100217604(VAV2) 100220994(VAV3)
FAB: 
PHI: 
FPG: 
101910791(VAV2) 101913030(VAV3) 101923354(VAV1)
FCH: 
CLV: 
ASN: 
102367839(VAV2) 102371823(VAV3) 102381892(VAV1)
AMJ: 
102562790(VAV1) 102565264(VAV2) 102570444(VAV3)
PSS: 
102445163(VAV2) 102458824(VAV3) 102462291(VAV1)
CMY: 
102932349(VAV3) 102935594(VAV2) 102941218(VAV1)
ACS: 
100564713(vav3) 100567031(vav2)
PBI: 
XLA: 
379646(MGC68892) 446826(vav1)
XTR: 
DRE: 
556413(vav2) 559145(vav3b)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103174755(vav3) 103182968(vav2)
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
AME: 
413488(GB13170)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG16186(Cbr-vav-1)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
SMM: 
NVE: 
TAD: 
AQU: 
MBR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Hunter SG, Zhuang G, Brantley-Sieders D, Swat W, Cowan CW, Chen J
  Title
Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis.
  Journal
Mol Cell Biol 26:4830-42 (2006)
  Sequence
[mmu:22325 57257]

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