KEGG ORTHOLOGY: K05764

ORTHOLOGY: K05764

Entry

K05764                      KO

Symbol

TMSB4

Name

thymosin, beta 4

Pathway

map04810

Regulation of actin cytoskeleton

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05764  TMSB4; thymosin, beta 4
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K05764  TMSB4; thymosin, beta 4
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Thymosin
     K05764  TMSB4; thymosin, beta 4

Genes

HSA:	7114(TMSB4X) 9087(TMSB4Y)

PTR:	101058899 101059399 104007609 465493(TMSB4X)

PPS:	100987645 103784229 103785151 103785506 103786747 112440511 117977621(TMSB4X)

GGO:	101131259 101152912(TMSB4X) 109024295

PON:	100173314(TMSB4X) 103891142 103891799

NLE:	100586905(TMSB4X) 101179388

HMH:	116461128 116463097 116463126 116809588 116812262(TMSB4X)

MCC:	106995404 114676950 710959(TMSB4X)

MCF:	102127641 123571114(TMSB4X)

MTHB:

126940158 126940705 126945714 126946672 126950064 126954764 126956130

MNI:	105478272(TMSB4X)

CSAB:

103231603(TMSB4X)

CATY:

105574712(TMSB4X) 105592075

PANU:

101021035(TMSB4X) 116272333

TGE:	112615031(TMSB4X) 112621470 112627064

MLEU:

105550029(TMSB4X)

RRO:	104657315 104678077(TMSB4X)

RBB:	108520703(TMSB4X)

TFN:	117069475 117071591 117078150(TMSB4X) 117082992 117085595

PTEH:

111520249 111522328 111531688(TMSB4X) 111551829

CANG:

105517290 105518046(TMSB4X)

CJC:	100392150 100399195(TMSB4X) 100399497 100410377 103787614 103787919 103788967 103794171 118153797

SBQ:	104650983(TMSB4X)

CIMI:

108288896 108289377 108304905 108317590 119468246 119471502

CSYR:

103261809 103264132 103268519 103269809 103272116 103273373

MMUR:

105882437(TMSB4X) 109730368

LCAT:

123627995(TMSB4X) 123628887 123629086 123632663

PCOQ:

105808462 105821997 105824570

OGA:	100953997 100960952 100966053(TMSB4X) 111723228

MMU:	19241(Tmsb4x)

MCAL:

110286700(Tmsb4x)

MPAH:

110313482(Tmsb4x)

RNO:	103692338(Tmsb4xl2) 120094392 120095326 120096885 81814(Tmsb4x)

MCOC:

116100927 116101268(Tmsb4x)

ANU:	117695451(Tmsb4x) 117709959

MUN:	110559826 110566561(Tmsb4x)

CGE:	100774337 103163771 118239413

MAUA:

101840813(Tmsb4x) 101843363 121141187

PLEU:

114699182 114702040 114702939(Tmsb4x) 114706375

MORG:

121439492(Tmsb4x) 121444431

MFOT:

126512679

AAMP:

119801377 119802017 119804838(Tmsb4x) 119808072

NGI:	103736273 103749967(Tmsb4x)

HGL:	101726037(Tmsb4x)

CPOC:

100736168(Tmsb4x)

DORD:

105997661(Tmsb4x)

DSP:	122108525(Tmsb4x)

PLOP:

125343952(Tmsb4x)

NCAR:

124972417 124989237

OCU:

127485645

TUP:	102490149 106734016

GVR:	103595881 103597041

CFA:	100683370 100684977(TMSB4X) 100686562 102152706 102153128 102156038 102156243 102157022 111092429 111094520 111098654 119866177

CLUD:

112641366 112644094 112650431 112652923(TMSB4X) 112659033 112662978 112670126 112670450 112671984 112676916 118352361 125752430

VVP:	112912562 112913177 112932374(TMSB4X) 112932873

VLG:	121473603 121475035 121475389 121475426 121476247 121483583(TMSB4X) 121484091 121493607 121494315 121498094 121500681

NPO:	129497342 129498166 129501857 129512351 129514170 129518215(TMSB4X) 129522081 129523045 129523199

AML:	100465730(TMSB4X) 105241849 117799178

UMR:	103678316 103682607 121099774(TMSB4X)

UAH:	113240727(TMSB4X) 113248368 113267056

UAR:	123788269 123788659 123791354 123796367(TMSB4X) 123798856 123803836

ELK:	111139463 111157089

LLV:	125081712 125083800 125089859 125091678 125092617 125092774 125099025 125099060 125100573 125105009 125106706

MPUF:

101674359 101686475(TMSB4X)

MNP:	132005156 132005238 132006969(TMSB4X) 132008041 132012202 132013210 132014019 132016370

MLK:	131818207 131818823 131820700 131820748(TMSB4X) 131825586 131826555 131828887 131829555 131830520 131835365

NVS:	122894476 122897001 122897234(TMSB4X) 122901174 122913735

ORO:	101363856 101369247(TMSB4X) 101375913 101381115 101381377

EJU:	114196837 114203691 114204859 114215850 114217292 114218040(TMSB4X)

ZCA:	113909966 113912974 113918360 113920062 113920131 113921706 113922957 113924121 113929607 113930221 113930732 113930795(TMSB4X) 113934450 113935664 113935678 118355939

MLX:	118006256 118006414 118008568 118009324 118013638 118016517 118021544 118022882 118023839 118025919 118026719(TMSB4X)

NSU:	110570548 110573402 110573752(TMSB4X) 110580532 110581101 110585870 110586355 110586536 110590166 110590979 110593846

LWW:	102744307(TMSB4X) 115937458

FCA:	101083316 101084579 101088815(TMSB4X) 102902079 109496027

PYU:	121021267 121030377 121034739 121038160

PCOO:

112851932 112871639(TMSB4X)

PBG:	122468213 122476911(TMSB4X) 122485339 122496041

PVIV:

125156166 125157427(TMSB4X) 125167580

LRUF:

124507415 124509350 124519152 124521307 124526206

PTG:	102957343 102964367(TMSB4X)

PPAD:

109248295(TMSB4X)

PUC:	125923956 125924852 125931480 125936890

AJU:	106979765 113593697 113597691 128314245

HHV:	120222208 120233139(TMSB4X) 120247490 120248272

BTA:	101906565 112441594 112443468 132344337 282386(TMSB4X) 785745

BOM:	102282148(TMSB4X) 102284203

BIU:	109555310(TMSB4X)

BBUB:

102400520 102408521(TMSB4X) 102413106 123330998

BBIS:

104981309(TMSB4X) 104992846 104992938 104993636

CHX:	102182562 102467078(TMSB4X)

OAS:	101102859 101119695(TMSB4X) 105602398 105609988 114114600

ODA:	120853583 120854703 120867640 120872966 120873649 120882449(TMSB4X)

CCAD:

122421209 122424907 122428344 122431405 122434952(TMSB4X) 122435477 122436418 122447516 122450429

SSC:	110257905 733606(TMSB4X)

CFR:	102513534 102517367(TMSB4X) 116663341

CBAI:

105070697 105077755(TMSB4X) 105082361

CDK:	105085609 105104035 116150826(TMSB4X)

VPC:	102542158(TMSB4X)

BACU:

103013570 103013918 103017932(TMSB4X)

BMUS:

118887180 118888357 118889210(TMSB4X) 118889468 118903060

LVE:	103076075 103082311(TMSB4X)

OOR:	101273310 101280441 101287861(TMSB4X) 101288882 105748330 117199847

DLE:	111167214(TMSB4X)

PCAD:

102991719(TMSB4X)

PSIU:

116740266 116745323 116747691(TMSB4X) 116754331

NASI:

112397576 112401846

ECB:	100034015(TMSB4X)

EPZ:	103552230(TMSB4X)

EAI:	106843063 106848622(TMSB4X)

MYB:	102238686 102243622 102258778(TMSB4X) 106725993

MYD:	102765056 102775435(TMSB4X) 107183964 107184314

MMYO:

118650943 118651348 118654191(TMSB4X) 118656428 118667414 118669954

MLF:	102427623(TMSB4X) 102437671 102438960

PKL:	118714209 118720033(TMSB4X) 118720740 118722721

EFUS:

103286495 103299726(TMSB4X) 114230917 129148706 129149737 129151493

MNA:

107525072

DRO:

112316977

SHON:

118980980 118982678 118982680 118983072 118987229(TMSB4X) 119000067 119000842 119003553

AJM:	119036564 119038262 119045876 119052763 119052766 119055086 119058331(TMSB4X) 119059062 119060013 119064675 119065533

PDIC:

114489889 114494311 114497806 114498412 114500980 114502021 114504322 114505231(TMSB4X) 114514844 118498517 118498778 118499353 118500199 118500645 118501112

PHAS:

123808634 123809508 123811857 123814534 123816323 123816774 123817522 123819583 123819697 123821608 123827829 123828590 123830016(TMSB4X) 123831354

MMF:	118618617 118628268 118630150 118631223 118636432(TMSB4X) 118642345

PPAM:

129070267 129076805 129076900(TMSB4X) 129078301 129079877 129082281 129082289 129083367 129083506 129084534

HAI:	109387357(TMSB4X)

RFQ:	117023829 117026948 117027067 117028776(TMSB4X) 117029073

PALE:

102888843(TMSB4X) 102893652

PVP:	105293982(TMSB4X)

RAY:	107497575(TMSB4X) 107506326

MJV:	118972785(TMSB4X)

TOD:	119246339(TMSB4X) 119246783 119250755 119258726

SARA:

101555822(TMSB4X)

SETR:

125999119(TMSB4X) 126003333 126013525

LAV:	100668370(TMSB4X) 111750095

TMU:

101348206

ETF:	101644072(TMSB4X) 105979637

DNM:	101414099 111761136 111764963

MDO:	100017869(TMSB4X) 100617751 100619033

GAS:	123239682(TMSB4X) 123251822 123252227

SHR:	100921944(TMSB4X)

AFZ:

127553642

PCW:	110199283 110222454(TMSB4X)

OAA:	100082242(TMSB4X)

GGA:	408047(TMSB4X) 770993(TMSB4Y)

PCOC:

116230750(TMSB4X) 116232190

MGP:

100539160

CJO:	107320133 107325932(TMSB4X)

TPAI:

128071698(TMSB4X) 128084070

LMUT:

125693719(TMSB4X) 125700105

NMEL:

110405293(TMSB4X)

APLA:

101796464 113841592(TMSB4X)

ACYG:

106032794(TMSB4X)

CATA:

118245770(TMSB4X) 118254919

AFUL:

116494776 116501949(TMSB4X)

TGU:	100190752(TMSB4X) 100232010

LSR:	110473214(TMSB4X) 110482711

SCAN:

103815807(TMSB4X) 103817276

PMOA:

120498617 120504632(TMSB4X)

OTC:	121332367 121342230(TMSB4X)

PRUF:

121356195(TMSB4X) 121361399

GFR:	102041951 102043761(TMSB4X)

FAB:	101817032 101820252(TMSB4X)

OMA:	130256864(TMSB4X) 130258588

PHI:	102104803(TMSB4X) 102105621

PMAJ:

107205483(TMSB4X) 107210896

CCAE:

111922816(TMSB4X) 111935573

CCW:	104686151(TMSB4X) 104689605

CBRC:

103611725(TMSB4X) 103614664

ETL:	114065208 114068932(TMSB4X)

ZAB:	102066892 102071605(TMSB4X)

ACHL:

103807408(TMSB4X)

SVG:	106852904(TMSB4X) 106857365

MMEA:

130577972 130588439(TMSB4X)

HRT:	120748552(TMSB4X) 120759254

FPG:

101922739

FCH:

102057308

CLV:	102087997 102093701(TMSB4X)

EGZ:	104128435(TMSB4X)

NNI:	104018453(TMSB4X)

PCRI:

104026783(TMSB4X)

PLET:

104615313(TMSB4X)

EHS:	104508719(TMSB4X)

PCAO:

104050991(TMSB4X)

ACUN:

113485195(TMSB4X)

TALA:

104366358 116963585(TMSB4X)

PADL:

103915764(TMSB4X)

AFOR:

103904414

ACHC:

115334130 115334602(TMSB4X)

HALD:

104312823(TMSB4X)

HLE:	104838875(TMSB4X)

AGEN:

126050918 126052912

GCL:	127016427 127022050

CCRI:

104163491(TMSB4X)

CSTI:

104552614(TMSB4X)

CMAC:

104482426(TMSB4X)

MUI:	104534927 104541718(TMSB4X)

BREG:

104643225(TMSB4X)

FGA:	104080415(TMSB4X)

GSTE:

104253194(TMSB4X)

LDI:	104346547(TMSB4X)

MNB:	103780369(TMSB4X)

OHA:	104326879(TMSB4X)

NNT:	104404754 104407231(TMSB4X)

SHAB:

115615599

DPUB:

104297073(TMSB4X) 104309771

ACAR:

104529563(TMSB4X)

CPEA:

104386626

AVIT:

104272549(TMSB4X)

CVF:	104291838(TMSB4X)

RTD:	128904053(TMSB4X) 128916166

CUCA:

104059218(TMSB4X)

TEO:	104381940(TMSB4X)

BRHI:

104490320(TMSB4X)

AAM:	106491689(TMSB4X)

AROW:

112964604(TMSB4X) 112964779

NPD:	112954086(TMSB4X) 112954518

TGT:	104580784(TMSB4X)

DNE:	112984243 112993564(TMSB4X)

SCAM:

104141074 104149807(TMSB4X)

ASN:	102372878(TMSB4X) 102379609

AMJ:	102564466(TMSB10) 102577269(TMSB4X)

CPOO:

109306062(TMSB4X) 109310122

GGN:	109289926 109303190(TMSB4X)

PSS:	102445810(TMSB4X)

CMY:	102936580(TMSB4X) 114022056

CCAY:

125634789 125641243(TMSB4X)

DCC:	119846647(TMSB4X)

CPIC:

101946282(TMSB4X)

TST:	117869846(TMSB4X)

CABI:

116834069(TMSB4X)

MRV:	120401258(TMSB4X)

ACS:	100558923 100560572(tmsb4x)

ASAO:

132768915 132771673(TMSB4X)

PVT:	110073493 110075478(TMSB4X)

SUND:

121926208(TMSB4X)

PBI:	103048757 103053440(TMSB4X)

PMUR:

107289018 107302470(TMSB4X)

CTIG:

120306498(TMSB4X) 120310620

TSR:	106557433(TMSB4X)

PGUT:

117655722 117676114(TMSB4X)

APRI:

131192022 131199896(TMSB4X)

PTEX:

113433510 113445184(TMSB4X)

NSS:	113411702(TMSB4X) 113424882

VKO:	123024398(TMSB4X) 123035852

PMUA:

114596288(TMSB4X)

PRAF:

128402412 128407910 128413210(TMSB4X)

ZVI:	118081534 118084643(TMSB4X)

HCG:	128342471 128352396(TMSB4X)

GJA:	107124268(TMSB4X) 107125501

STOW:

125431653(TMSB4X)

EMC:	129326478(TMSB4X) 129335588 129342530

XLA:	108709680 399438(tmsb4x.L)

XTR:	733468(tmsb4x)

NPR:	108794930(TMSB4X)

RTEM:

120924959 120926527(TMSB4X)

BBUF:

120995635(TMSB4X)

BGAR:

122931141(TMSB4X)

MUO:	115469188(TMSB4X)

GSH:	117363098(TMSB4X)

DRE:	402820(tmsb) 566329(tmsb2) 793949(tmsb4x)

SRX:	107742637(tmsb4x)

SANH:

107667660(tmsb4x)

SGH:	107552380(tmsb4x)

CCAR:

109055448 109081903 109093913 109094599 109113719(tmsb4x)

CAUA:

113038537 113044360 113052908 113057711 113058139 113063754 113080004 113108206 113113906

CGIB:

127942155 127949669 127964788 127970961 127986621 128020247 128027130

PTET:

122326749(tmsb) 122333058(tmsb4x) 122348417 122357381(tmsb2)

LROH:

127152395(tmsb) 127171007(tmsb4x) 127176575(tmsb2)

OMC:	131529029(tmsb) 131542446 131546820(tmsb4x)

PPRM:

120479172(tmsb4x)

RKG:	130072547(tmsb4x) 130087809 130095188(tmsb2)

MAMB:

125252741(tmsb) 125259292(tmsb2) 125270862(tmsb4x) 125272311

CIDE:

127494616 127503838 127514847 127518377

MASI:

127412964 127417879 127428864 127443750 127447011 127448290

MANU:

129422396(tmsb2) 129424512(tmsb) 129451955(tmsb4x)

IPU:	100304709(tmsb4x) 108258993 128633468 128635338

IFU:	128601886 128609283(tmsb4x) 128611160(tmsb2) 128622406(tmsb)

PHYP:

113524350

SMEO:

124378237 124379970(tmsb4x) 124386167(tmsb2)

TFD:	113635530 113635593(tmsb2) 113642092 113646952(tmsb) 113649010(tmsb4x)

TVC:	132839324(tmsb4x) 132855996(tmsb2) 132860030(tmsb) 132861004

AMEX:

103024855 103025385 111195815

CMAO:

118797910 118807134(tmsb2) 118811369(tmsb4x) 118819969(tmsb)

EEE:	113571291 113587186 113588867

TRU:

115252437

TFS:	130531579(tmsb2)

TNG:	GSTEN00031637G001

LCO:	104924244 104935059

NCC:	104947323 104949035

TBEN:

117475184(tmsb2) 117499164

CGOB:

115015172 115026842

PGEO:

117453358(tmsb2)

GACU:

117545202(tmsb2)

ELY:	117255705 117260707(tmsb2)

EFO:	125884878 125894381(tmsb2)

SLUC:

116044686 116052079(tmsb2)

ECRA:

117939145 117951983(tmsb2)

ESP:

116696951

PFLV:

114551187 114562901

GAT:	120818489(tmsb2)

PPUG:

119211601(tmsb2) 119218983

AFB:	129089869(tmsb2) 129111767

CLUM:

117737423(tmsb2) 117743024

PSWI:

130204382 130210111(tmsb2)

MSAM:

119888170(tmsb2) 119903756

SCHU:

122872079 122880869(tmsb2)

ALAT:

119015093 119025635(tmsb4x)

MZE:	101466144(tmsb4x) 101466672

ONL:	100702585(tmsb4x)

OAU:	116315142(tmsb2) 116323112

XMA:	102217051 102221182 111609250

XCO:	114140476 114148007

XHE:	116714833 116716175(tmsb4x)

PRET:

103459176 103474715

PFOR:

103132075 103151925(tmsb4x) 107835635

PLAI:

106937274 106942154(tmsb4x)

PMEI:

106924958 106931093

GAF:	122827154 122837564(tmsb2)

PPRL:

129355472 129363032(tmsb2)

CVG:	107095749(tmsb4x)

CTUL:

119780967(tmsb2) 119788793(tmsb4x) 119792314

GMU:	124861014(tmsb2) 124861626

NFU:	107380871(tmsb4x) 107395803

KMR:	108245807(tmsb2) 108246798

ALIM:

106525723

NWH:	119409107(tmsb2) 119415020 119419167(tmsb4x) 119419480 119428836

AOCE:

111580292(tmsb4x)

CSEM:

103389531

POV:

109645526

SSEN:

122765459 122778139(tmsb2)

HHIP:

117755084(tmsb4x) 117769345(tmsb2) 117775769

HSP:	118103541 118112664(tmsb2) 118120518(tmsb4x)

SMAU:

118282482 118319406(tmsb2)

LCF:	108882789(tmsb2) 108890952 108892885

SDU:	111226672 111236729

SLAL:

111664638 111665347

XGL:	120785362(tmsb2) 120798337

HCQ:	109524190 109528309

SSCV:

125986900 125987979

SBIA:

133508712(tmsb2)

PEE:	133407778(tmsb2) 133412403

PTAO:

133478368 133484662(tmsb2) 133486819(tmsb4x)

BPEC:

110162402

MALB:

109956696 109960580(tmsb4x)

BSPL:

114846769(tmsb4x) 114851182 114864821(tmsb2)

SJO:	128354341 128363087(tmsb2)

SASA:

100195705(tmsb4x) 106586813(TYB12) 106604357

STRU:

115148453 115153916 115161347(tmsb4x) 115168494 115205603

OTW:	112225288 112234667 112253741 112257068 112258325 121840376

OMY:	100136027 100170202 110533318(tmsb) 110537822 118936315 118938712(tmsb2) 118946058

OGO:	123994164(tmsb2) 123995165 124000623 124011677 124044253(tmsb4x)

ONE:	115104643 115113550 115119477 115121687 115127955

OKI:	109873183 109878950 116354937 116374415

OKE:	118366706(tmsb4x) 118373461(tmsb2) 118390670 118391022 127913948

SALP:

111950754 111980683

SNH:	120033759 120044424 120047932 120050599 120056418 120062049 120064358

CCLU:

121536189(tmsb4x) 121536776(tmsb2) 121546005 121574080 121580140

ELS:	105018723 105020018 114839106 114839531

SFM:	108920507 108927832

PKI:	111846862(tmsb4x) 111848913 111851511

AANG:

118214617(tmsb4x) 118222500(tmsb2) 118231303 118235463

LOC:	102682393(tmsb4x) 102687759

PSPA:

121297387(tmsb2) 121320653 121324043 121327477

ARUT:

117405122 117406516 117413066 117431400 117971112

PSEX:

120516400 120532374 120542718(tmsb2)

CMK:

RTP:

CPLA:

HOC:

LERI:

LRJ:

APLC:

Reference

PMID:6201851

Authors

Wodnar-Filipowicz A, Gubler U, Furuichi Y, Richardson M, Nowoswiat EF, Poonian MS, Horecker BL

Title

Cloning and sequence analysis of cDNA for rat spleen thymosin beta 4.

Journal

Proc Natl Acad Sci U S A 81:2295-7 (1984)
DOI:10.1073/pnas.81.8.2295

Sequence

[rno:81814]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Gene (1883)   
   KEGG GENES (1022)   
   KEGG MGENES (8)   
   RefGene (843)   
   OC (10)   
Literature (1)   
   PubMed (1)   
All databases (1888)   

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