KEGG ORTHOLOGY: K05867

ORTHOLOGY: K05867

Entry

K05867                      KO

Symbol

CDC25C

Name

M-phase inducer phosphatase 3 [EC:3.1.3.48]

Pathway

map04110

Cell cycle

map04114

Oocyte meiosis

map04914

Progesterone-mediated oocyte maturation

map05170

Human immunodeficiency virus 1 infection

map05206

MicroRNAs in cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K05867  CDC25C; M-phase inducer phosphatase 3
   04114 Oocyte meiosis
    K05867  CDC25C; M-phase inducer phosphatase 3
09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K05867  CDC25C; M-phase inducer phosphatase 3
09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K05867  CDC25C; M-phase inducer phosphatase 3
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05867  CDC25C; M-phase inducer phosphatase 3
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K05867  CDC25C; M-phase inducer phosphatase 3
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K05867  CDC25C; M-phase inducer phosphatase 3
   03400 DNA repair and recombination proteins
    K05867  CDC25C; M-phase inducer phosphatase 3
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     K05867  CDC25C; M-phase inducer phosphatase 3
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K05867  CDC25C; M-phase inducer phosphatase 3
Protein tyrosine phosphatases (PTPs)
  Class III PTPs
   CDC25s
    K05867  CDC25C; M-phase inducer phosphatase 3
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Centrosome formation proteins
   Centrosome duplication proteins
    Other centrosome duplication proteins
     K05867  CDC25C; M-phase inducer phosphatase 3
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  Check point factors
   Other check point factors
    K05867  CDC25C; M-phase inducer phosphatase 3

Other DBs

GO:

0004725

Genes

HSA:	995(CDC25C)

PTR:	746151(CDC25C)

PPS:	100990018(CDC25C)

GGO:	101150213(CDC25C)

PON:	100451443(CDC25C)

NLE:	100588617(CDC25C)

HMH:	116471552(CDC25C)

MCC:	714115(CDC25C)

MCF:	101866661(CDC25C)

MTHB:

126957362

MNI:	105467080(CDC25C)

CSAB:

103244613(CDC25C)

CATY:

105599837(CDC25C)

PANU:

101017717(CDC25C)

TGE:	112625735(CDC25C)

MLEU:

105551840(CDC25C)

RRO:	104681726(CDC25C)

RBB:	108541696(CDC25C)

TFN:	117065805(CDC25C)

PTEH:

111528664(CDC25C)

CANG:

105506977(CDC25C)

CJC:	100387914(CDC25C)

SBQ:	101041558(CDC25C)

CIMI:

108284257(CDC25C) 108297658

CSYR:

103261706(CDC25C)

MMUR:

105862589(CDC25C)

LCAT:

123637817(CDC25C)

PCOQ:

105812033(CDC25C)

OGA:	100964410(CDC25C)

MMU:	12532(Cdc25c)

MCAL:

110284647(Cdc25c)

MPAH:

110333485(Cdc25c)

MCOC:

116086979(Cdc25c)

ANU:	117719745(Cdc25c)

MUN:	110558466(Cdc25c)

CGE:	100773417(Cdc25c)

MAUA:

101828859(Cdc25c)

PROB:

127235110(Cdc25c)

PLEU:

114705113(Cdc25c)

MORG:

121443029 121453320

MFOT:

126497036

AAMP:

119814812(Cdc25c)

NGI:	103735158(Cdc25c)

HGL:	101712931(Cdc25c)

CCAN:

109700186(Cdc25c)

DORD:

105988647(Cdc25c)

DSP:	122118179(Cdc25c)

PLOP:

125339885(Cdc25c)

NCAR:

124987233

MMMA:

107141294(Cdc25c)

OCU:

100343637

OPI:	101519435(CDC25C)

TUP:	102499060(CDC25C)

GVR:	103590544(CDC25C)

CFA:	610456(CDC25C)

CLUD:

112649793(CDC25C)

VVP:	112921903(CDC25C)

VLG:	121494351(CDC25C)

NPO:	129495050(CDC25C)

AML:	100482691(CDC25C)

UMR:	103663783(CDC25C)

UAH:	113261495(CDC25C)

UAR:	123790307(CDC25C)

LLV:

125100775

MPUF:

101678023(CDC25C)

MNP:	132028550(CDC25C)

MLK:	131832093(CDC25C)

NVS:	122891205(CDC25C)

ORO:	101367041(CDC25C)

EJU:	114209504(CDC25C)

ZCA:	113929304(CDC25C)

MLX:	118016681(CDC25C)

NSU:	110591218(CDC25C)

LWW:	102749369(CDC25C)

FCA:	101086942(CDC25C)

PYU:	121010761(CDC25C)

PCOO:

112860266(CDC25C)

PBG:	122487894(CDC25C)

PVIV:

125173403(CDC25C)

LRUF:

124516125

PTG:	102968740(CDC25C)

PPAD:

109252124(CDC25C)

PUC:

125935547

AJU:

106967966

HHV:	120220748(CDC25C)

BTA:	507731(CDC25C)

BOM:	102287313(CDC25C)

BIU:	109562060(CDC25C)

BBUB:

102401152(CDC25C)

BBIS:

104991822(CDC25C)

CHX:	102187214(CDC25C)

OAS:	101110327(CDC25C)

BTAX:

128051380(CDC25C)

ODA:	120863610(CDC25C)

CCAD:

122439872(CDC25C)

MBEZ:

129558754(CDC25C)

SSC:	100144474(CDC25C)

CFR:	102516690(CDC25C)

CBAI:

105082163(CDC25C)

CDK:	105090655(CDC25C)

VPC:	102534342(CDC25C)

BACU:

103014243(CDC25C)

BMUS:

118892864(CDC25C)

LVE:	103088476(CDC25C)

OOR:	101276884(CDC25C)

DLE:	111182493(CDC25C)

PCAD:

102978115(CDC25C)

PSIU:

116752324(CDC25C)

NASI:

112404397(CDC25C)

ECB:	100062352(CDC25C)

EPZ:	103551352(CDC25C)

EAI:	106839210(CDC25C)

MYB:	102262547(CDC25C)

MYD:	102761242(CDC25C)

MMYO:

118658931(CDC25C)

MLF:	102419273(CDC25C)

PKL:	118711716(CDC25C)

EFUS:

103289927(CDC25C)

MNA:	107530121(CDC25C)

DRO:	112318157(CDC25C)

SHON:

118997533(CDC25C)

AJM:	119051049(CDC25C)

PDIC:

114509524(CDC25C)

PHAS:

123809892(CDC25C)

MMF:	118615143(CDC25C)

PPAM:

129066655(CDC25C)

HAI:	109392993(CDC25C)

RFQ:	117016695(CDC25C)

PALE:

102894193(CDC25C)

PGIG:

120581351(CDC25C)

PVP:	105293614(CDC25C)

RAY:	107518727(CDC25C)

MJV:	108385295(CDC25C)

TOD:	119243428(CDC25C)

SARA:

101545153(CDC25C)

SETR:

126027034(CDC25C)

LAV:	100670954(CDC25C)

TMU:

101342935

ETF:	101645781(CDC25C)

DNM:	101412555(CDC25C)

MDO:	100014440 100025023(CDC25C)

GAS:	123233861(CDC25C)

SHR:	100924438(CDC25C)

AFZ:

127549958

PCW:	110220848(CDC25C)

AAM:	106487224(CDC25C)

AROW:

112964852(CDC25C)

NPD:	112952895(CDC25C)

TGT:	104571367(CDC25C)

DNE:	112994068(CDC25C)

SCAM:

104140178(CDC25C)

ASN:	102384314(CDC25C)

AMJ:	102572255(CDC25C)

CPOO:

109310259(CDC25C)

GGN:	109289807(CDC25C)

PSS:	102456953(CDC25C)

CMY:	102945797(CDC25C)

CCAY:

125641116(CDC25C)

DCC:	119860328(CDC25C)

CPIC:

101952003(CDC25C)

TST:	117882039(CDC25C)

CABI:

116828122(CDC25C)

MRV:	120370938(CDC25C)

ACS:	100565034(cdc25c)

ASAO:

132769076(CDC25C)

PVT:	110077149(CDC25C)

SUND:

121922253(CDC25C)

PBI:	103051692(CDC25C)

PMUR:

107289189(CDC25C) 107299702

CTIG:

120304014(CDC25C)

TSR:	106545415(CDC25C)

PGUT:

117679529(CDC25C)

APRI:

131190211(CDC25C)

PTEX:

113449923(CDC25C)

NSS:	113415708(CDC25C)

VKO:	123034167(CDC25C)

PMUA:

114591472(CDC25C)

PRAF:

128408096(CDC25C)

ZVI:	118081558(CDC25C)

HCG:	128342734(CDC25C)

GJA:

107107149

STOW:

125429658(CDC25C)

EMC:	129328612(CDC25C)

XLA:	100337563(cdc25c.S) 398119(cdc25c.L)

XTR:	100124300(cdc25c)

NPR:	108797600(CDC25C)

RTEM:

120932164(CDC25C)

BBUF:

120978692(CDC25C)

BGAR:

122928120(CDC25C)

CHAR:

SASA:

STRU:

OTW:

OMY:

OGO:

ONE:	115101434(cdc25c)

OKI:	109874256(cdc25c)

OKE:

SALP:

SNH:

CCLU:

ELS:	105010884(cdc25c)

SFM:	108934112(cdc25c)

PKI:	111850200(cdc25c)

AANG:

PSPA:

ARUT:

PSEX:

LCM:	102356985(CDC25C)

CMK:

CPLA:

HOC:

LERI:

AGRG:

PPYR:

DSV:

RMP:

ABRU:

PVUL:

HRJ:	124284793 124284799

CVN:	111132547 111132548 111132549 111132550 111132551

CANU:

128169095 128179376 128179723

MCAF:

127702014

» show all

Reference

PMID:2195549

Authors

Sadhu K, Reed SI, Richardson H, Russell P

Title

Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2.

Journal

Proc Natl Acad Sci U S A 87:5139-43 (1990)
DOI:10.1073/pnas.87.13.5139

Sequence

[hsa:995]

Reference

PMID:8119945

Authors

Strausfeld U, Fernandez A, Capony JP, Girard F, Lautredou N, Derancourt J, Labbe JC, Lamb NJ

Title

Activation of p34cdc2 protein kinase by microinjection of human cdc25C into mammalian cells. Requirement for prior phosphorylation of cdc25C by p34cdc2 on sites phosphorylated at mitosis.

Journal

J Biol Chem 269:5989-6000 (1994)

Sequence

[hsa:995]

All links

Ontology (6)   
   KEGG BRITE (5)   
   GO (1)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (379)   
   KEGG GENES (237)   
   KEGG MGENES (16)   
   RefGene (124)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (398)   

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