KEGG   ORTHOLOGY: K05870Help
Entry
K05870                      KO                                     

Name
CREB1
Definition
cyclic AMP-responsive element-binding protein 1
Pathway
PI3K-Akt signaling pathway
Adrenergic signaling in cardiomyocytes
Osteoclast differentiation
Antigen processing and presentation
TNF signaling pathway
Circadian rhythm
Circadian entrainment
Cholinergic synapse
Dopaminergic synapse
Insulin secretion
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Vasopressin-regulated water reabsorption
Huntington's disease
Cocaine addiction
Amphetamine addiction
Alcoholism
Tuberculosis
Hepatitis B
HTLV-I infection
Viral carcinogenesis
Prostate cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04668 TNF signaling pathway
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
   04151 PI3K-Akt signaling pathway
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
 Organismal Systems
  Immune system
   04612 Antigen processing and presentation
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
  Endocrine system
   04911 Insulin secretion
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
   04915 Estrogen signaling pathway
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
   04918 Thyroid hormone synthesis
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
   04916 Melanogenesis
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
  Nervous system
   04725 Cholinergic synapse
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
   04728 Dopaminergic synapse
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
  Development
   04380 Osteoclast differentiation
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
  Environmental adaptation
   04710 Circadian rhythm
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
   04713 Circadian entrainment
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
   05215 Prostate cancer
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
  Neurodegenerative diseases
   05016 Huntington's disease
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
  Substance dependence
   05030 Cocaine addiction
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
   05031 Amphetamine addiction
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
   05034 Alcoholism
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
  Infectious diseases
   05152 Tuberculosis
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
   05166 HTLV-I infection
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
   05161 Hepatitis B
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Basic leucine zipper (bZIP)
   CREB
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Ubiquitas transcription factors
    K05870  CREB1; cyclic AMP-responsive element-binding protein 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
1385(CREB1)
PTR: 
459901(CREB1)
PPS: 
100974672(CREB1)
GGO: 
101144410(CREB1)
PON: 
100294619(CREB1)
MCC: 
708717(CREB1)
MCF: 
102141699(CREB1)
MMU: 
12912(Creb1)
RNO: 
81646(Creb1)
CGE: 
100761582(Creb1)
HGL: 
101712503(Creb1)
TUP: 
102500092(CREB1)
CFA: 
607922(CREB1)
AML: 
FCA: 
101091299(CREB1)
BTA: 
281713(CREB1)
BOM: 
102281756(CREB1)
PHD: 
102316751(CREB1)
CHX: 
102186065(CREB1)
SSC: 
397449(CREB1)
CFR: 
102508765(CREB1)
ECB: 
100066388(CREB1)
MYB: 
102246867(CREB1)
MDO: 
SHR: 
100913327(CREB1)
OAA: 
GGA: 
395099(CREB1)
MGP: 
100542127(CREB1)
TGU: 
751585(CREB1)
FAB: 
101811066(CREB1)
PHI: 
102101211(CREB1)
APLA: 
101791404(CREB1)
FPG: 
101911755(CREB1)
FCH: 
102050642(CREB1)
CLV: 
102085492(CREB1)
ASN: 
102385124(CREB1)
PSS: 
102450649(CREB1)
ACS: 
XLA: 
379764(creb1)
XTR: 
407934(creb1)
DRE: 
573207(creb1a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102361965(CREB1)
CIN: 
100101830(creb/atf-c)
SPU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lonze BE, Ginty DD
  Title
Function and regulation of CREB family transcription factors in the nervous system.
  Journal
Neuron 35:605-23 (2002)
Reference
  Authors
Mayr B, Montminy M
  Title
Transcriptional regulation by the phosphorylation-dependent factor CREB.
  Journal
Nat Rev Mol Cell Biol 2:599-609 (2001)

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