KEGG ORTHOLOGY: K05917

ORTHOLOGY: K05917

Entry

K05917 KO

Name

CYP51

Definition

cytochrome P450, family 51 (sterol 14-demethylase) [EC:1.14.13.70]

Pathway

ko00100

Steroid biosynthesis

Module

M00101

Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Lipid metabolism
   00100 Steroid biosynthesis
    K05917  CYP51; cytochrome P450, family 51 (sterol 14-demethylase)
KEGG pathway modules [BR:ko00002]
Pathway module
  Carbohydrate and lipid metabolism
   Sterol biosynthesis
    M00101  Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol
     K05917  CYP51; cytochrome P450, family 51 (sterol 14-demethylase)
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.70  sterol 14alpha-demethylase
     K05917  CYP51; cytochrome P450, family 51 (sterol 14-demethylase)
Cytochrome P450 [BR:ko00199]
Cytochrome P450, animal type
  CYP51 family
   CYP51A subfamily
    K05917  CYP51; cytochrome P450, family 51 (sterol 14-demethylase)

Other DBs

RN:

R05640 R05731

COG:

COG2124

GO:

0008398

Genes

HSA:	1595(CYP51A1)
PTR:	463527(CYP51A1)
PPS:	100985833
GGO:	101127636
PON:	100171776(CYP51A1)
MCC:	703490
MMU:	13121(Cyp51)
RNO:	25427(Cyp51)
CFA:	475225(CYP51A1)
AML:	100477744
FCA:	101083499
BTA:	505060(CYP51A1)
SSC:	403334(CYP51)
ECB:	100050921
MDO:	100028071
SHR:	100916047
OAA:	100087589
GGA:	420548(CYP51A1)
MGP:	100538580
TGU:	100220976
ACS:	100557431
XLA:	100037098(cyp51a1) 447600
XTR:	548948(cyp51a1)
DRE:	414331(cyp51)
TRU:	101062187
OLA:	101169834
BFO:	BRAFLDRAFT_115377
SPU:	414330(cyp51)
TAD:	TRIADDRAFT_22681
AQU:	100636481
ATH:	AT1G11680(CYP51G1)
ALY:	ARALYDRAFT_471307
GMX:	100799526 100810799
MTR:	MTR_8g006450
CSV:	101205062
RCU:	RCOM_1438480
POP:	POPTR_48605(CYP51G1) POPTR_554675(CYP51G5)
VVI:	100242104 100252340
OSA:	4328054 4329175 4338097 4338803 4350614
DOSA:	Os02t0113200-00(Os02g0113200) Os02t0323600-01(Os02g0323600) Os05t0211100-01(Os05g0211100) Os05t0416400-00(Os05g0416400) Os11t0525200-01(Os11g0525200)
BDI:	100830263 100832594 100844089 100845001
SBI:	SORBI_02g019410(SORBIDRAFT_02g019410) SORBI_02g036650(SORBIDRAFT_02g036650) SORBI_03g028910(SORBIDRAFT_03g028910) SORBI_05g011296(SORBIDRAFT_05g011296) SORBI_05g011430(SORBIDRAFT_05g011430) SORBI_05g019590(SORBIDRAFT_05g019590) SORBI_05g022310(SORBIDRAFT_05g022310) SORBI_05g022330(SORBIDRAFT_05g022330) SORBI_05g022340(SORBIDRAFT_05g022340) SORBI_05g022350(SORBIDRAFT_05g022350) SORBI_05g022360(SORBIDRAFT_05g022360) SORBI_05g022370(SORBIDRAFT_05g022370) SORBI_05g022720(SORBIDRAFT_05g022720) SORBI_08g002250(SORBIDRAFT_08g002250) SORBI_08g007250(SORBIDRAFT_08g007250)
ZMA:	100191975 100273258 100382691 100383359
SMO:	SELMODRAFT_178739(CYP51G1)
PPP:	PHYPADRAFT_134753
CRE:	CHLREDRAFT_196411(CYP51G1)
VCN:	VOLCADRAFT_72667
OLU:	OSTLU_43938
OTA:	Ot11g01460
CME:	CMS319C
SCE:	YHR007C(ERG11)
AGO:	AGOS_ADR162W
ERC:	Ecym_6045
KLA:	KLLA0E03653g
LTH:	KLTH0G05148g
PPA:	PAS_chr3_0957
VPO:	Kpol_1004p61 Kpol_1023p61
ZRO:	ZYRO0D14036g
CGR:	CAGL0E04334g
NCS:	NCAS_0G00960(NCAS0G00960)
NDI:	NDAI_0F01100(NDAI0F01100)
TPF:	TPHA_0D02710(TPHA0D02710)
TBL:	TBLA_0E02810(TBLA0E02810)
TDL:	TDEL_0A04550(TDEL0A04550)
KAF:	KAFR_0C05720(KAFR0C05720)
DHA:	DEHA2E19272g
PIC:	PICST_63421(CP51)
PGU:	PGUG_03415
LEL:	LELG_03738
CAL:	CaO19.922(ERG11)
CTP:	CTRG_05283
CDU:	CD36_50660(ERG11)
COT:	CORT_0E05900
YLI:	YALI0B05126g
CLU:	CLUG_04932
NCR:	NCU02624
SMP:	SMAC_05737
PAN:	PODANSg09698
TTT:	THITE_135170
MTM:	MYCTH_110187
MGR:	MGG_04432 MGG_04628
FGR:	FG01000.1 FG04092.1
NHE:	NECHADRAFT_43488 NECHADRAFT_57370
VAL:	VDBG_04839
SSL:	SS1G_04805
BFU:	BC1G_11853
ANI:	AN1901.2 AN8283.2
NFI:	NFIA_024690 NFIA_109350
AFM:	AFUA_4G06890 AFUA_7G03740
AOR:	AOR_1_1506014(AO090026000842) AOR_1_336154(AO090003000205)
ANG:	ANI_1_314094(An11g02230) ANI_1_518114(An13g00090)
AFV:	AFLA_036130 AFLA_131060
ACT:	ACLA_005420 ACLA_046180
PCS:	Pc12g10870 Pc20g09070
CIM:	CIMG_00573 CIMG_07469
CPW:	CPC735_044410 CPC735_056710
PBL:	PAAG_00827
URE:	UREG_00593 UREG_07804
ABE:	ARB_00950 ARB_05314
TVE:	TRV_00734 TRV_06889
AJE:	HCAG_04048 HCAG_04481
PNO:	SNOG_03702
PTE:	PTT_12247 PTT_15951
ZTR:	MYCGRDRAFT_110231(CYP-74)
TML:	GSTUM_00011943001
SPO:	SPAC13A11.02c(erg11)
CNE:	CNA00300
CNB:	CNBA0300
CGI:	CGB_B0330W
LBC:	LACBIDRAFT_234769
MPR:	MPER_02932 MPER_03805
CCI:	CC1G_07605 CC1G_08364
SCM:	SCHCODRAFT_55526
UMA:	UM03662.1
MGL:	MGL_2415
PGR:	PGTG_07202
MBR:	MONBRDRAFT_38433
NGR:	NAEGRDRAFT_48319 NAEGRDRAFT_82952
DDI:	DDB_G0279403(CYP51)
DPP:	DICPUDRAFT_93794
TBR:	Tb11.02.4080
TCR:	506297.260 510101.50
LMA:	LMJF_11_1100
LIF:	LINJ_11_1100
LDO:	LDBPK_111100
LMI:	LMXM_11_1100
LBZ:	LBRM_11_0880
PTI:	PHATRDRAFT_31339
TPS:	THAPSDRAFT_33926
MCA:	MCA2711(cyp51)
MAH:	MEALZ_0770(cyp)
GPB:	HDN1F_11100(cyp51)
NAR:	Saro_3659
NPP:	PP1Y_Mpl3478
MTU:	Rv0764c(cyp51)
MTV:	RVBD_0764c
MTC:	MT0788
MRA:	MRA_0773(cyp51)
MTF:	TBFG_10779
MTB:	TBMG_00779
MTK:	TBSG_00783
MTZ:	TBXG_000772
MTG:	MRGA327_04755
MTI:	MRGA423_04780
MTE:	CCDC5079_0706
MTL:	CCDC5180_0698
MTO:	MTCTRI2_0783(cyp51)
MTN:	ERDMAN_0846(cyp51)
MTJ:	J112_04110
MTUB:	MT7199_0785
MBO:	Mb0787c(cyp51)
MBB:	BCG_0816c(cyp51)
MBT:	JTY_0786(cyp51)
MBM:	BCGMEX_0787c(cyp51)
MBK:	K60_008170
MAF:	MAF_07760(cyp51)
MCE:	MCAN_07681(cyp51)
MCQ:	BN44_10834(cyp)
MCV:	BN43_20199(cyp)
MCX:	BN42_20522(cyp)
MCZ:	BN45_20033(cyp)
MPA:	MAP0598c
MAV:	MAV_0708
MIT:	OCO_06010 OCO_10820
MIR:	OCQ_06160
MIA:	OCU_06050
MID:	MIP_01081
MSM:	MSMEG_5863
MSG:	MSMEI_5704(cyp51)
MSA:	Mycsm_05681
MUL:	MUL_0473(cyp51B1)
MVA:	Mvan_5161
MGI:	Mflv_1596
MSP:	Mspyr1_09820
MAB:	MAB_1214c
MMV:	MYCMA_0649(cyp51)
MMC:	Mmcs_4582
MKM:	Mkms_4670
MJL:	Mjls_4965
MJD:	JDM601_3604(cyp51B1)
MMI:	MMAR_4932(cyp51B1)
MRH:	MycrhN_2410
MMM:	W7S_02950
MCB:	Mycch_4522
NFA:	nfa25890(cyp51)
NCY:	NOCYR_4381(cyp)
NBR:	O3I_020205
RHA:	RHA1_ro04671
RER:	RER_33770(cyp51)
ROP:	ROP_47700(cyp51)
REQ:	REQ_13820
GBR:	Gbro_3843
GPO:	GPOL_c37060(cyp)
GOR:	KTR9_3783
SEN:	SACE_3928(cyp51)
SESP:	BN6_77630(cyp51)

» show all

Reference

PMID:1872829

Reference

PMID:11437378

All links

Ontology (10)   
   KEGG BRITE (8)   
   GO (1)   
   COG (1)   
Pathway (24)   
   KEGG PATHWAY (6)   
   KEGG MODULE (18)   
Drug (54)   
   KEGG DRUG (54)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
Gene (741)   
   KEGG GENES (252)   
   KEGG DGENES (19)   
   KEGG EGENES (425)   
   KEGG MGENES (45)   
Protein sequence (210)   
   UniProt (210)   
Literature (2)   
   PubMed (2)   
All databases (1045)   

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