KEGG   ORTHOLOGY: K06062Help
Entry
K06062                      KO                                     

Name
PCAF, KAT2, GCN5
Definition
histone acetyltransferase [EC:2.3.1.48]
Pathway
ko04330  Notch signaling pathway
ko04919  Thyroid hormone signaling pathway
ko05166  HTLV-I infection
ko05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04330 Notch signaling pathway
    K06062  PCAF, KAT2, GCN5; histone acetyltransferase
 Organismal Systems
  Endocrine system
   04919 Thyroid hormone signaling pathway
    K06062  PCAF, KAT2, GCN5; histone acetyltransferase
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K06062  PCAF, KAT2, GCN5; histone acetyltransferase
  Infectious diseases
   05166 HTLV-I infection
    K06062  PCAF, KAT2, GCN5; histone acetyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     K06062  PCAF, KAT2, GCN5; histone acetyltransferase
Transcription machinery [BR:ko03021]
 Eukaryotic type
  RNA polymerase II system
   Coactivators
    SAGA/TFTC/STAGA complex
     K06062  PCAF, KAT2, GCN5; histone acetyltransferase
Chromosome [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HATs (histone acetyltransferases)
    K06062  PCAF, KAT2, GCN5; histone acetyltransferase
   HAT complexes
    PCAF complex
     K06062  PCAF, KAT2, GCN5; histone acetyltransferase
    STAGA complex
     K06062  PCAF, KAT2, GCN5; histone acetyltransferase
    TFTC complex
     K06062  PCAF, KAT2, GCN5; histone acetyltransferase
    SAGA complex
     K06062  PCAF, KAT2, GCN5; histone acetyltransferase
    SLIK complex
     K06062  PCAF, KAT2, GCN5; histone acetyltransferase
    ADA-HAT complex
     K06062  PCAF, KAT2, GCN5; histone acetyltransferase
    HAT-A2 complex
     K06062  PCAF, KAT2, GCN5; histone acetyltransferase
BRITE hierarchy
Other DBs
GO: 0004402
Genes
HSA: 2648(KAT2A) 8850(KAT2B)
PTR: 454677(KAT2A) 460219(KAT2B)
PPS: 100979198(KAT2B) 100984656(KAT2A)
GGO: 101125556(KAT2A) 101145647(KAT2B)
PON: 100434727(KAT2A)
NLE: 100584880(KAT2B)
MCC: 698283(KAT2B) 706004(KAT2A)
MCF: 102115185(KAT2A) 102142689(KAT2B)
CSAB: 103241748(KAT2B) 103243423(KAT2A)
RRO: 104665709(KAT2B) 104680633(KAT2A)
RBB: 108518347(KAT2A) 108521249(KAT2B)
CJC: 100404275(KAT2A) 100414237(KAT2B)
SBQ: 101035750(KAT2B) 101044914(KAT2A)
MMU: 14534(Kat2a) 18519(Kat2b)
RNO: 301164(Kat2b) 303539(Kat2a)
CGE: 100772054(Kat2b) 100774478(Kat2a)
NGI: 103734285(Kat2b) 103735888(Kat2a)
HGL: 101711015(Kat2b) 101724847(Kat2a)
OCU: 100346295(KAT2B) 100347774(KAT2A) 100353065
TUP: 102476156(KAT2B) 102480159(KAT2A)
CFA: 477052(KAT2B) 490971(KAT2A)
AML: 100468755(KAT2A) 100482031(KAT2B)
UMR: 103672619(KAT2A) 103681930(KAT2B)
ORO: 101369712(KAT2B) 101370446(KAT2A)
FCA: 101080732(KAT2B) 101094713(KAT2A)
PTG: 102955875(KAT2B) 102972197(KAT2A)
AJU: 106972603(KAT2A) 106981451(KAT2B)
BTA: 407215(KAT2B) 514420(KAT2A)
BOM: 102273269(KAT2B) 102284799(KAT2A)
BIU: 109563564(KAT2B) 109574119(KAT2A)
PHD: 102318704(KAT2B) 102326656(KAT2A)
CHX: 102184382(KAT2B) 102184470(KAT2A)
OAS: 101109985(KAT2A) 101115756(KAT2B)
SSC: 100524215(KAT2A) 100626923(KAT2B)
CFR: 102511960(KAT2A) 102517009(KAT2B)
CDK: 105085150(KAT2B) 105090504(KAT2A)
BACU: 103010689(KAT2B)
LVE: 103080529(KAT2A) 103085599(KAT2B)
OOR: 101279017(KAT2A) 101283661(KAT2B)
ECB: 100053057(KAT2A) 100061976(KAT2B)
EPZ: 103550392(KAT2A) 103559353(KAT2B)
EAI: 106826413(KAT2A) 106831750(KAT2B)
MYB: 102256768(KAT2B) 102257744(KAT2A)
MYD: 102757677(KAT2A) 102765994(KAT2B)
HAI: 109393983(KAT2B) 109395783(KAT2A)
RSS: 109444544(KAT2B) 109455780(KAT2A)
PALE: 102885647(KAT2B) 102885891(KAT2A)
LAV: 100668740(KAT2A) 100671393(KAT2B)
MDO: 100012508(KAT2A) 100031193(KAT2B)
SHR: 100922650(KAT2A) 100926508(KAT2B)
OAA: 100077074(KAT2B) 100084553(KAT2A)
GGA: 374232(KAT2A) 428441(KAT2B)
MGP: 100543932(KAT2B) 100548985(KAT2A)
CJO: 107309257(KAT2B) 107325120(KAT2A)
APLA: 101792577(KAT2A) 101805426(KAT2B)
ACYG: 106030266(KAT2B)
TGU: 100221709(KAT2A) 100227387(KAT2B)
GFR: 102036361(KAT2B) 102043992(KAT2A)
FAB: 101819015(KAT2A) 101820857(KAT2B)
PHI: 102100634(KAT2A) 102111563(KAT2B)
PMAJ: 107215120(KAT2A) 107215650(KAT2B)
CCW: 104689063(KAT2B) 104697811(KAT2A)
FPG: 101912497(KAT2B) 101920637(KAT2A)
FCH: 102046828(KAT2A) 102057415(KAT2B)
CLV: 102083878(KAT2A) 102091620(KAT2B)
EGZ: 104124456(KAT2A) 104126077(KAT2B)
AAM: 106483559(KAT2B) 106487634(KAT2A)
ASN: 102367884(KAT2B) 102370665(KAT2A)
AMJ: 102558317(KAT2A) 102572176(KAT2B)
PSS: 102445835(KAT2A) 102448076(KAT2B)
CMY: 102932561(KAT2B) 102940936(KAT2A)
CPIC: 101938841(KAT2B) 101941570(KAT2A)
ACS: 100555803(kat2b) 100556199(kat2a)
PVT: 110074848(KAT2A) 110086852(KAT2B)
PBI: 103060138(KAT2B) 103067908(KAT2A)
GJA: 107111474(KAT2A) 107123658(KAT2B)
XTR: 100488927(kat2b) 100492735(kat2a)
NPR: 108788931(KAT2A) 108797631(KAT2B)
DRE: 555517(kat2a) 563942(kat2b)
IPU: 108272723(kat2b) 108278374(kat2a)
AMEX: 103026885 103044670(kat2a)
TRU: 101070909(kat2b) 101072241(kat2a)
LCO: 104923119(kat2b) 104926017(kat2a)
NCC: 104953325(kat2b) 104958097(kat2a)
MZE: 101477349(kat2b) 101482035(kat2a)
OLA: 101159205 101170930(kat2a)
XMA: 102221720(kat2b) 102222338(kat2a)
PRET: 103469408(kat2a) 103472353(kat2b)
NFU: 107381933(kat2a) 107394764
CSEM: 103393177(kat2a) 103394359(kat2b)
BPEC: 110161530(kat2a) 110167419(kat2b)
ELS: 105012607(kat2b) 105013345(kat2a)
LCM: 102346903(KAT2A) 102366092(KAT2B)
CMK: 103181274(kat2b) 103189181(kat2a)
CIN: 100176452(kat2a) 100183071(kat2b)
SPU: 579684(kat2b)
APLC: 110979345
SKO: 100378710
DME: Dmel_CG4107(Gcn5)
DSI: Dsimw501_GD12710(Dsim_GD12710)
MDE: 101887625
AAG: 5577348
AME: 552646(KAT2A)
BIM: 100745103
BTER: 100648411
NVI: 100119143
TCA: 658128
DPA: 109537414
BMOR: 101736749
PRAP: 110999395
ZNE: 110831336
FCD: 110842718
TUT: 107370140
CEL: CELE_Y47G6A.6(pcaf-1)
CBR: CBG14939(Cbr-pcaf-1)
BMY: Bm1_38035
TSP: Tsp_05985
CRG: 105331688
MYI: 110460610
OBI: 106871034
ADF: 107340536
AQU: 100635137
ATH: AT3G54610(HAG1)
CPAP: 110814751
CIT: 102610789
TCC: 18613245
GRA: 105803152
DZI: 111314274
VRA: 106757920
VAR: 108347988
CCAJ: 109809225
CAM: 101502210
ADU: 107493159
AIP: 107645225
LJA: Lj1g3v4450300.1(Lj1g3v4450300.1)
PPER: 18767118
PMUM: 103334174
PAVI: 110763443
MDM: 103445732
PXB: 103957328
ZJU: 107425866
CSV: 101203446
CMO: 103484257
MCHA: 111015748
RCU: 8274721
JCU: 105649909
HBR: 110659668
JRE: 109008788
SLY: 101253033
SPEN: 107002772
SOT: 102584794
CANN: 107845455
NTA: 107787386
NSY: 104234642
NTO: 104112773
SIND: 105165321
HAN: 110884050
BVG: 104894583
SOE: 110783711
NNU: 104589649
OSA: 4348629
DOSA: Os10t0415900-01(Os10g0415900)
OBR: 102712297
BDI: 100824513
ATS: 109771315(LOC109771315)
SBI: 8064917
ZMA: 542030(hag101)
SITA: 101784841
PDA: 103711623
EGU: 105053422
MUS: 103993868
DCT: 110114546
AOF: 109821377
ATR: 18429542
SMO: SELMODRAFT_139448(HAG1-1) SELMODRAFT_450903(HAG1-2)
OLU: OSTLU_33057(HAG3501)
APRO: F751_5642
SCE: YGR252W(GCN5)
ERC: Ecym_5099
KMX: KLMA_40434(GCN5)
NCS: NCAS_0E03900(NCAS0E03900)
NDI: NDAI_0D04630(NDAI0D04630)
TPF: TPHA_0H01180(TPHA0H01180)
TBL: TBLA_0C06610(TBLA0C06610)
TDL: TDEL_0G00890(TDEL0G00890)
KAF: KAFR_0B04450(KAFR0B04450)
CAL: CAALFM_CR06710CA(GCN5)
CAUR: QG37_01315
SLB: AWJ20_1341(GCN5)
NCR: NCU10847(ngf-1)
NTE: NEUTE1DRAFT142084(NEUTE1DRAFT_142084)
NHE: NECHADRAFT_105852(HAG2101) NECHADRAFT_123019(HAG2102)
MBE: MBM_09741
ANI: AN3621.2
ANG: ANI_1_1086014(An01g08160) ANI_1_1528124(An14g05810)
ZTR: MYCGRDRAFT_40511(HAG2402)
SPO: SPAC1952.05(gcn5)
CNE: CNA03280
CNB: CNBA3150
LBC: LACBIDRAFT_319636(HAG16201)
ABP: AGABI1DRAFT36691(AGABI1DRAFT_36691)
ABV: AGABI2DRAFT70461(AGABI2DRAFT_70461)
MGL: MGL_1714
DDI: DDB_G0283459(gcn5)
EHI: EHI_140660(60.t00011)
PFA: PF08_0034(gcn5)
PYO: PY17X_0707600(PY02679)
PCB: PCHAS_071660(PC000316.01.0)
TAN: TA20705
TPV: TP01_0465
BBO: BBOV_I003750(19.m02034)
CPV: cgd3_3190
TGO: TGME49_243440(GCN5B)
AAF: AURANDRAFT_25661(HAG1)
SPAR: SPRG_00458
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Nagy Z, Tora L
  Title
Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.
  Journal
Oncogene 26:5341-57 (2007)
DOI:10.1038/sj.onc.1210604
Reference
  Authors
Lee KK, Workman JL
  Title
Histone acetyltransferase complexes: one size doesn't fit all.
  Journal
Nat Rev Mol Cell Biol 8:284-95 (2007)
DOI:10.1038/nrm2145

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