KEGG   ORTHOLOGY: K06236Help
Entry
K06236                      KO                                     

Name
COL1A
Definition
collagen, type I, alpha
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Platelet activation
Relaxin signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Protein digestion and absorption
Amoebiasis
Human papillomavirus infection
Disease
H00506  
Osteogenesis imperfecta
H00613  
Infantile cortical hyperostosis
H00802  
Ehlers-Danlos syndrome (EDS)
H01593  
Osteoporosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06236  COL1A; collagen, type I, alpha
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06236  COL1A; collagen, type I, alpha
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K06236  COL1A; collagen, type I, alpha
 Organismal Systems
  Immune system
   04611 Platelet activation
    K06236  COL1A; collagen, type I, alpha
  Endocrine system
   04926 Relaxin signaling pathway
    K06236  COL1A; collagen, type I, alpha
  Digestive system
   04974 Protein digestion and absorption
    K06236  COL1A; collagen, type I, alpha
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K06236  COL1A; collagen, type I, alpha
  Infectious diseases
   05165 Human papillomavirus infection
    K06236  COL1A; collagen, type I, alpha
   05146 Amoebiasis
    K06236  COL1A; collagen, type I, alpha
Cell adhesion molecules and their ligands [BR:ko04516]
 2. Integrin Family
  Beta1 integrins
   VLA-1
    ITGB1; integrin beta 1
     K06236 COL1A; collagen, type I, alpha
   VLA-2
    ITGB1; integrin beta 1
     K06236 COL1A; collagen, type I, alpha
   alpha 11 beta 1
    ITGB1; integrin beta 1
     K06236 COL1A; collagen, type I, alpha
 4. Link Protein Family
  CD44; CD44 antigen
   K06236 COL1A; collagen, type I, alpha
 7. Others
  SDC1; syndecan 1
   K06236 COL1A; collagen, type I, alpha
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Extracellular matrix molecules
   K06236  COL1A; collagen, type I, alpha
BRITE hierarchy
Genes
HSA: 
1277(COL1A1) 1278(COL1A2)
PTR: 
104001053(COL1A1) 455117(COL1A2)
PPS: 
100974826(COL1A2) 100991060(COL1A1)
GGO: 
101130610(COL1A1) 101142769(COL1A2)
PON: 
100438152(COL1A1) 100439107(COL1A2)
NLE: 
MCC: 
574201(COL1A1) 700359(COL1A2)
MCF: 
102128759(COL1A1) 102130586(COL1A2)
CSAB: 
RRO: 
104680270(COL1A1) 104682783(COL1A2)
RBB: 
108516437(COL1A1) 108517180(COL1A2)
CJC: 
100386176(COL1A1) 100411438(COL1A2)
SBQ: 
101045518(COL1A2) 101051510(COL1A1) 104651959
MMU: 
12842(Col1a1) 12843(Col1a2)
RNO: 
103689932(NEWGENE_621351) 29393(Col1a1) 84352(Col1a2)
CGE: 
100759814(Col1a1) 100766269(Col1a2)
NGI: 
103725222(Col1a2) 103738382(Col1a1)
HGL: 
101703193(Col1a1) 101722393(Col1a2) 101726257
CCAN: 
OCU: 
100008997(COL1A2) 100347598(COL1A1) 103351483
TUP: 
102469999(COL1A1) 102495359 102496034(COL1A2)
CFA: 
403651(COL1A1) 403824(COL1A2)
AML: 
100474885(COL1A2) 100476237(COL1A1)
UMR: 
103658736(COL1A2) 103660945(COL1A1) 103675284
FCA: 
101089428(COL1A2) 101092216(COL1A1) 102901092(FAAP20) 105261147
PTG: 
102967512(COL1A1) 102971076(COL1A2)
AJU: 
106969999(COL1A2) 106985166(COL1A1)
BTA: 
282187(COL1A1) 282188(COL1A2)
BOM: 
102265105(COL1A1) 102267202(COL1A2)
BIU: 
109558214(COL1A2) 109573749(COL1A1) 109575219
PHD: 
CHX: 
OAS: 
SSC: 
100626716(COL1A2) 100738123(COL1A1)
CFR: 
102510097(COL1A1) 102520737(COL1A2)
CDK: 
105088734(COL1A2) 105104820(COL1A1)
BACU: 
LVE: 
ECB: 
100033877(COL1A1) 100051715(COL1A2)
EPZ: 
103549571(COL1A1) 103553631(COL1A2)
EAI: 
106826321(COL1A1) 106838933(COL1A2)
MYB: 
102253918(COL1A2) 102259707(COL1A1)
MYD: 
102770947(COL1A2) 102772822(COL1A1)
HAI: 
109371948(COL1A2) 109379905 109380648(COL1A1)
RSS: 
109446389(COL1A2) 109447012(COL1A1)
PALE: 
102878069(COL1A2) 102886463(COL1A1)
LAV: 
MDO: 
100019354(COL1A1)
SHR: 
100916041(COL1A2) 100924667(COL1A1)
OAA: 
100078516 100079519(COL1A1) 100681278(COL1A2)
GGA: 
395532(COL1A1) 396243(COL1A2)
MGP: 
100540436(COL1A2)
CJO: 
107309082(COL1A2) 107325218(COL1A1)
APLA: 
101794718(COL1A2) 101800457(COL1A1)
ACYG: 
TGU: 
100221003(COL1A2)
GFR: 
FAB: 
PHI: 
102100227(COL1A2) 102104738(COL1A1) 106628211
PMAJ: 
107199012(COL1A1) 107200743(COL1A2) 107211448
CCW: 
104689333(COL1A2)
FPG: 
101921645(COL1A2) 101924780(COL1A1)
FCH: 
102046312(COL1A1) 102047033(COL1A2)
CLV: 
102090396(COL1A2) 102092022(COL1A1)
AAM: 
ASN: 
102372309(COL1A2) 102376361(COL1A1)
AMJ: 
102565404(COL1A1) 102568819(COL1A2)
PSS: 
102445411(COL1A1) 102457083(COL1A2) 106732816
CMY: 
CPIC: 
101942871(COL1A2) 101946870 101949941(COL1A1)
ACS: 
100559991(col1a2) 100565711(col1a1)
PVT: 
110074712(COL1A2) 110079135(COL1A1)
PBI: 
103053762(COL1A2) 103055359(COL1A1)
GJA: 
107112523(COL1A1) 107118003(COL1A2) 107125148
XLA: 
108700840(col1a1.L) 108719903(col1a2.S) 380419(col1a2.L) 380515(col1a1.S)
XTR: 
496414(col1a1) 780175(col1a2)
NPR: 
108784001(COL1A1) 108786596 108790501(COL1A2)
DRE: 
325675(col1a1b) 336471(col1a2) 337158(col1a1a)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
101475669 101476419(col1a1) 101486099(col1a2)
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102345189(COL1A2) 102349893(COL1A1)
CMK: 
BFO: 
API: 
DNX: 
DPX: 
HRO: 
CRG: 
LAK: 
SMM: 
OVI: 
EPA: 
ADF: 
AQU: 
ATS: 
ZMA: 
CRE: 
VCN: 
MNG: 
MIS: 
MPP: 
CSL: 
CVR: 
APRO: 
TRE: 
GLZ: 
SCM: 
PFP: 
ACAN: 
AAF: 
EHX: 
SALS: 
SGU: 
STRE: 
SRN: 
NGV: 
AMN: 
PSEA: 
PSEE: 
PSEQ: 
PECQ: 
PHH: 
AFS: 
PHM: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2394758
  Authors
Weil D, D'Alessio M, Ramirez F, Eyre DR
  Title
Structural and functional characterization of a splicing mutation in the pro-alpha 2(I) collagen gene of an Ehlers-Danlos type VII patient.
  Journal
J Biol Chem 265:16007-11 (1990)
  Sequence
[hsa:1278]

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