KEGG   ORTHOLOGY: K06237Help
Entry
K06237                      KO                                     

Name
COL4A
Definition
collagen, type IV, alpha
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Protein digestion and absorption
Amoebiasis
Pathways in cancer
Small cell lung cancer
Disease
H00579  
Hereditary angiopathy with nephropathy, aneurysms, and muscle cramps (HANAC)
H00581  
Alport syndrome
H00582  
Benign familial hematuria
H00839  
Porencephaly
H00877  
Brain small vessel disease with Axenfeld-Rieger anomaly
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06237  COL4A; collagen, type IV, alpha
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06237  COL4A; collagen, type IV, alpha
 Cellular Processes
  Cellular commiunity
   04510 Focal adhesion
    K06237  COL4A; collagen, type IV, alpha
 Organismal Systems
  Digestive system
   04974 Protein digestion and absorption
    K06237  COL4A; collagen, type IV, alpha
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K06237  COL4A; collagen, type IV, alpha
   05222 Small cell lung cancer
    K06237  COL4A; collagen, type IV, alpha
  Infectious diseases
   05146 Amoebiasis
    K06237  COL4A; collagen, type IV, alpha
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   K06237  COL4A; collagen, type IV, alpha
Cell adhesion molecules and their ligands [BR:ko04516]
 2. Integrin Family
  Beta1 integrins
   VLA-1
    ITGB1; integrin beta 1
     K06237 COL4A; collagen, type IV, alpha
   VLA-2
    ITGB1; integrin beta 1
     K06237 COL4A; collagen, type IV, alpha
   VLA-3
    ITGB1; integrin beta 1
     K06237 COL4A; collagen, type IV, alpha
   alpha 10 beta 1
    ITGB1; integrin beta 1
     K06237 COL4A; collagen, type IV, alpha
  Beta3 integrins
   VNR
    ITGB3; integrin beta 3
     K06237 COL4A; collagen, type IV, alpha
  Beta8 integrins
   alpha V beta 8
    ITGB8; integrin beta 8
     K06237 COL4A; collagen, type IV, alpha
 4. Link Protein Family
  CD44; CD44 antigen
   K06237 COL4A; collagen, type IV, alpha
 7. Others
  APP; amyloid beta A4 protein
   K06237 COL4A; collagen, type IV, alpha
Heparan sulfate/heparin binding proteins [BR:ko00536]
 Extracellular matrix molecules
  K06237  COL4A; collagen, type IV, alpha
BRITE hierarchy
Genes
HSA: 
1282(COL4A1) 1284(COL4A2) 1285(COL4A3) 1286(COL4A4) 1287(COL4A5) 1288(COL4A6)
PTR: 
452659(COL4A1) 452661(COL4A2) 459986(COL4A4) 459988(COL4A3) 465804(COL4A6) 465805(COL4A5)
PPS: 
100972511(COL4A4) 100972868(COL4A3) 100976901(COL4A1) 100977235(COL4A2) 100983653(COL4A6) 100984686(COL4A5)
GGO: 
101128311(COL4A1) 101130790(COL4A6) 101133910(COL4A5) 101136942(COL4A4) 101137308(COL4A3) 101149355(COL4A2)
PON: 
100443710(COL4A4) 100444077(COL4A3) 100444160(COL4A1) 100444523(COL4A2) 100457450(COL4A6) 100457807(COL4A5)
MCC: 
100429807(COL4A2) 700281(COL4A1) 703707(COL4A6) 703814(COL4A5) 708287(COL4A4) 712444(COL4A3)
MCF: 
102118598(COL4A4) 102122146(COL4A3) 102122606(COL4A1) 102125366(COL4A6) 102127262(COL4A5) 102131342(COL4A2)
MMU: 
12826(Col4a1) 12827(Col4a2) 12828(Col4a3) 12829(Col4a4) 12830(Col4a5) 94216(Col4a6)
RNO: 
290905(Col4a1) 306628(Col4a2) 363265(Col4a3) 363457(Col4a5) 363458(Col4a6)
CGE: 
100756006 100757740(Col4a1) 100766914(Col4a2)
HGL: 
101709004(Col4a3) 101709338(Col4a5) 101709839(Col4a4) 101710396(Col4a6) 101718501(Col4a1) 101721657(Col4a2)
TUP: 
102478229(COL4A3) 102479923(COL4A1) 102480773(COL4A2) 102486100(COL4A5) 102489000(COL4A6) 102494131(COL4A4)
CFA: 
403466(COL4A5) 403496(COL4A1) 403840(COL4A6) 403841(COL4A4) 403842(COL4A3) 403843(COL4A2)
AML: 
100478660(COL4A3) 100478752(COL4A1) 100478914(COL4A4) 100479004 100479688(COL4A6) 100480195
FCA: 
101087512(COL4A3) 101089498(COL4A6) 101091469(COL4A4) 101096030(COL4A1) 101096282(COL4A2)
PTG: 
102951304 102951890(COL4A5) 102962233(COL4A4) 102965883(COL4A3) 102965922(COL4A2) 102966202(COL4A1)
BTA: 
282191(COL4A1) 317711(COL4A3) 407107(COL4A4) 508632(COL4A2) 511602(COL4A5) 523526(COL4A6)
BOM: 
102265778(COL4A4) 102271607(COL4A5) 102272072(COL4A6) 102282491(COL4A2) 102282767(COL4A1) 102285223(COL4A3)
PHD: 
102315075(COL4A5) 102342203(COL4A1) 102342560(COL4A2) 102343336(COL4A3) 102343687(COL4A4) 102344964(COL4A6)
CHX: 
102171079(COL4A1) 102171347(COL4A2) 102176677(COL4A6) 102176947(COL4A5) 102190083(COL4A4) 102190364(COL4A3)
SSC: 
100153454(COL4A2) 100515336(COL4A1) 100519180(COL4A5) 100620724(COL4A6) 100621403(COL4A4)
CFR: 
102508830(COL4A2) 102509068(COL4A1) 102520494(COL4A6) 102521464(COL4A5) 102524319(COL4A3) 102524585(COL4A4)
BACU: 
103009501(COL4A5) 103009884(COL4A1) 103009983(COL4A6) 103010470(COL4A2) 103010606(COL4A4) 103020723(COL4A3)
LVE: 
103070575(COL4A6) 103074830(COL4A3) 103078804(COL4A4) 103088369(COL4A1) 103089438(COL4A2) 103091674(COL4A5)
ECB: 
100037402(COL4A3) 100054545(COL4A5) 100060112(COL4A6) 100062160(COL4A4) 100066148(COL4A1) 100066264(COL4A2)
MYB: 
102242641(COL4A6) 102243536(COL4A2) 102248314(COL4A3) 102249405(COL4A4) 102249508(COL4A1) 102256779(COL4A5)
MYD: 
102752490(COL4A2) 102752777(COL4A1) 102764359(COL4A4) 102764638(COL4A3) 102768696(COL4A5) 102774545(COL4A6)
PALE: 
102879139(COL4A3) 102879385(COL4A4) 102891781(COL4A5) 102895248(COL4A6) 102897825 102898083(COL4A2) 102898331(COL4A1)
MDO: 
100021663(COL4A3) 100021728(COL4A4) 100023678(COL4A2) 100023705(COL4A1) 100025514(COL4A5)
SHR: 
100915861 100917328(COL4A3) 100917586(COL4A4) 100923249(COL4A2) 100923506(COL4A1) 100925517 100931618(COL4A5)
OAA: 
100073948(COL4A4) 100078067(COL4A5) 100084401(COL4A1) 100084415(COL4A2)
GGA: 
395530(COL4A1) 418752(COL4A2) 422348(COL4A5) 422350(COL4A6) 424797(COL4A3) 424799(COL4A4)
MGP: 
TGU: 
100218909(COL4A2) 100221489(COL4A3) 100224679(COL4A1) 100226545 100227313(COL4A4)
FAB: 
101807691(COL4A5) 101807885(COL4A6) 101810620(COL4A4) 101810814(COL4A3) 101814259 101814446(COL4A1) 101814637(COL4A2) 101819201
PHI: 
102100218(COL4A1) 102101909(COL4A4) 102102271(COL4A3) 102102406 102106135(COL4A6) 102106323(COL4A5) 102111682(COL4A2)
APLA: 
101797440(COL4A4) 101797613(COL4A3) 101799662(COL4A5) 101800228(COL4A6) 101803874(COL4A2) 101804910(COL4A1)
FPG: 
101918166(COL4A6) 101918345(COL4A5) 101922424(COL4A4) 101922604(COL4A3) 101924055(COL4A2) 101924227(COL4A1)
FCH: 
102046549(COL4A2) 102046717(COL4A1) 102051664(COL4A3) 102051835(COL4A4) 102052258(COL4A5) 102052429(COL4A6)
CLV: 
102083797(COL4A4) 102083978(COL4A3) 102085871(COL4A6) 102088881(COL4A1) 102089261(COL4A2) 102090256(COL4A5)
ASN: 
102375031(COL4A1) 102375357(COL4A4) 102380122(COL4A5) 102380767(COL4A6) 102388567(COL4A2)
AMJ: 
102558085(COL4A6) 102558315(COL4A5) 102558707 102559838(COL4A2) 102576967(COL4A4) 102577197(COL4A3)
PSS: 
102443377(COL4A6) 102445225(COL4A3) 102445487(COL4A4) 102455715(COL4A1) 102455954(COL4A2) 102458094(COL4A5)
CMY: 
102933966(COL4A2) 102934197(COL4A1) 102942604(COL4A6) 102942829(COL4A5) 102946071(COL4A4) 102946297(COL4A3)
ACS: 
PBI: 
XTR: 
100124870(col4a1) 100486079(col4a2) 100492984(col4a5) 100493153(col4a6)
DRE: 
323561(col4a5) 553355(col4a2) 554268(col4a6) 554269(col4a1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102346118(COL4A5) 102346381(COL4A6) 102348817(COL4A3) 102349091 102349357 102351071(COL4A2) 102351330(COL4A1)
CMK: 
BFO: 
CIN: 
SPU: 
373182(COLP3alpha)
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
CQU: 
AME: 
408551(GB14564) 408552(GB13353)
NVI: 
TCA: 
BMOR: 
101736620 692625(Let-2) 693056(CPR146)
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG16372(Cbr-let-2)
BMY: 
LOA: 
TSP: 
SMM: 
HMG: 
TAD: 
ELA: 
PNO: 
RDN: 
FBC: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Gordon MK, Hahn RA
  Title
Collagens.
  Journal
Cell Tissue Res 339:247-57 (2010)

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