KEGG   ORTHOLOGY: K06268Help
Entry
K06268                      KO                                     

Name
PPP3R, CNB
Definition
serine/threonine-protein phosphatase 2B regulatory subunit
Pathway
MAPK signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Oocyte meiosis
Wnt signaling pathway
Axon guidance
VEGF signaling pathway
Osteoclast differentiation
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Long-term potentiation
Glutamatergic synapse
Oxytocin signaling pathway
Glucagon signaling pathway
Renin secretion
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
Amphetamine addiction
Tuberculosis
HTLV-I infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04310 Wnt signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04370 VEGF signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04020 Calcium signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04022 cGMP - PKG signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04660 T cell receptor signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04662 B cell receptor signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  Endocrine system
   04922 Glucagon signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04921 Oxytocin signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04924 Renin secretion
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  Nervous system
   04724 Glutamatergic synapse
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04720 Long-term potentiation
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  Development
   04360 Axon guidance
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04380 Osteoclast differentiation
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   05014 Amyotrophic lateral sclerosis (ALS)
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  Substance dependence
   05031 Amphetamine addiction
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  Infectious diseases
   05152 Tuberculosis
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   05166 HTLV-I infection
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
BRITE hierarchy
Other DBs
COG: 
GO: 
Genes
HSA: 
5534(PPP3R1) 5535(PPP3R2)
PTR: 
100613118(PPP3R1) 736325(PPP3R2)
PPS: 
100995767(PPP3R2)
GGO: 
101125510(PPP3R1) 101144871(PPP3R2)
PON: 
100461146(PPP3R2) 103889825(PPP3R1)
NLE: 
100593195(PPP3R1) 100600788(PPP3R2)
MCC: 
100428682(PPP3R1) 574258(PPP3R2)
MCF: 
101866439(PPP3R2) 102137250(PPP3R1)
RRO: 
104670806(PPP3R2) 104675975(PPP3R1)
CJC: 
100388148(PPP3R1) 100392986(PPP3R2)
MMU: 
19058(Ppp3r1) 19059(Ppp3r2)
RNO: 
29748(Ppp3r1) 29749(Ppp3r2)
CGE: 
100754314(Ppp3r2) 100773706(Ppp3r1)
NGI: 
103734750(Ppp3r1) 103749104(Ppp3r2)
HGL: 
101706255(Ppp3r1) 101710684(Ppp3r2)
OCU: 
100344533(PPP3R2)
TUP: 
102474096(PPP3R1) 102478386(PPP3R2)
CFA: 
610453(PPP3R2) 612559(PPP3R1)
AML: 
100467683(PPP3R1) 100474742(PPP3R2)
UMR: 
103671340(PPP3R1) 103678534(PPP3R2)
FCA: 
101090344(PPP3R1) 101097765(PPP3R2)
PTG: 
102965200(PPP3R1) 102967427(PPP3R2)
BTA: 
282321(PPP3R1) 617585(PPP3R2)
BOM: 
102272271(PPP3R1) 102277736(PPP3R2)
PHD: 
102325503(PPP3R2) 102332014(PPP3R1)
CHX: 
102177339(PPP3R2) 102182602(PPP3R1)
OAS: 
101120802(PPP3R2)
SSC: 
CFR: 
106729683(PPP3R2)
BACU: 
103009602(PPP3R2)
LVE: 
103068473(PPP3R1) 103078845(PPP3R2)
ECB: 
100061874(PPP3R1) 102148270(PPP3R2)
MYB: 
102247129(PPP3R2) 102250711(PPP3R1)
MYD: 
102760712(PPP3R2) 102774846(PPP3R1)
PALE: 
102894471(PPP3R1) 102895490(PPP3R2)
MDO: 
100033302(PPP3R1)
SHR: 
100918689(PPP3R1)
OAA: 
100083665(PPP3R1)
GGA: 
378804(HZGJ)
MGP: 
100549150(PPP3R1)
CJO: 
107310666(PPP3R1)
APLA: 
101791746(PPP3R1)
TGU: 
100229058(PPP3R1)
GFR: 
102034017(PPP3R1)
FAB: 
101820532(PPP3R1)
PHI: 
102111343(PPP3R1)
CCW: 
104696602(PPP3R1)
FPG: 
101923629(PPP3R1)
FCH: 
102050745(PPP3R1)
CLV: 
102095954(PPP3R1)
AAM: 
106495909(PPP3R1)
ASN: 
102377091(PPP3R1)
AMJ: 
106737480(PPP3R1)
PSS: 
102448775(PPP3R1)
ACS: 
100561213(ppp3r1)
GJA: 
107114939(PPP3R1)
XLA: 
399215(ppp3r1) 444804
XTR: 
395037(ppp3r1)
DRE: 
447814(ppp3r1b) 564337(ppp3r1a)
TRU: 
MZE: 
OLA: 
XMA: 
102218918(ppp3r1)
LCM: 
102367157(PPP3R1)
CMK: 
103177901(ppp3r1)
BFO: 
CIN: 
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD15356(Dsim_GD15356) Dsimw501_GD29162(Dsim_GD29162)
DWI: 
DYA: 
Dyak_GE16397(dyak_GLEANR_17822) Dyak_GE19147(dyak_GLEANR_2922)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
551313(GB19283)
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
BMOR: 
692578(Cnb)
PXY: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG23183(Cbr-cnb-1)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
AT1G64480(CBL8) AT3G18430 AT4G01420(CBL5) AT4G16350(CBL6) AT4G17615(CBL1) AT4G26560(CBL7) AT4G26570(CBL3) AT4G33000(CBL10) AT5G24270(SOS3) AT5G47100(CBL9)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0001s10750g(POPTRDRAFT_548325) POPTR_0001s38060g(POPTRDRAFT_707736) POPTR_0003s02440g POPTR_0003s03000g POPTR_0003s03190g POPTR_0003s14130g(POPTRDRAFT_414023) POPTR_0006s00480g(POPTRDRAFT_831742) POPTR_0006s24630g(POPTRDRAFT_763265) POPTR_0011s09720g(POPTRDRAFT_660678) POPTR_0012s02230g(POPTRDRAFT_823210) POPTR_0015s01540g(POPTRDRAFT_732882) POPTR_0015s01550g(POPTRDRAFT_574749) POPTR_0016s00520g POPTR_0018s11260g(POPTRDRAFT_835941)
VVI: 
SLY: 
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
4325933(B1142C05.7) 4325962(CBL2) 4333502(CBL3) 4339432(CBL4) 4345696(P0708B04.4) 4351575(CBL6) 4352701(CBL2)
DOSA: 
Os01t0579600-01(Os01g0579600) Os01t0598200-01(Os01g0598200) Os01t0711500-00(Os01g0711500) Os02t0291000-00(Os02g0291000) Os02t0291400-00(Os02g0291400) Os02t0480800-00(Os02g0480800) Os02t0802400-01(Os02g0802400) Os03t0448500-01(Os03g0448500) Os03t0626800-01(Os03g0626800) Os05t0534400-01(Os05g0534400) Os08t0442300-01(Os08g0442300) Os08t0442350-01(Os08g0442350) Os10t0564800-01(Os10g0564800) Os12t0162400-01(Os12g0162400) Os12t0597000-01(Os12g0597000)
OBR: 
BDI: 
SBI: 
SORBI_01g028750(SORBIDRAFT_01g028750) SORBI_04g011330(SORBIDRAFT_04g011330) SORBI_04g036210(SORBIDRAFT_04g036210) SORBI_07g021780(SORBIDRAFT_07g021780) SORBI_07g021790(SORBIDRAFT_07g021790) SORBI_08g003930(SORBIDRAFT_08g003930) SORBI_08g020190(SORBIDRAFT_08g020190) SORBI_09g026650(SORBIDRAFT_09g026650)
ZMA: 
100191578(CBL1) 100192607(CBL2-2) 100193443(GRMZM2G085573) 100193926(GRMZM2G116584) 100282538(CBL2-1) 100282800(TIDP3120) 100283705(si496006g11) 100284760(GRMZM2G146948) 100284839(IDP1992) 100284952 100285425(GRMZM2G125838) 100285616 101027228(CBL5) 103640805(GRMZM2G033680) 103646236
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
BPG: 
MIS: 
MPP: 
CSL: 
CVR: 
APRO: 
CME: 
GSL: 
CCP: 
SCE: 
YKL190W(CNB1)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0A02710(NCAS0A02710)
NDI: 
NDAI_0D04640(NDAI0D04640)
TPF: 
TPHA_0B01930(TPHA0B01930)
TBL: 
TBLA_0I03160(TBLA0I03160)
TDL: 
TDEL_0H01410(TDEL0H01410)
KAF: 
KAFR_0A05790(KAFR0A05790)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
NCR: 
NCU03833(cnb-1)
NTE: 
NEUTE1DRAFT144368(NEUTE1DRAFT_144368)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_166114(AO090701000094)
ANG: 
ANI_1_152134(An15g00870)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
PPL: 
DSQ: 
SHS: 
HIR: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MPR: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT116228(AGABI1DRAFT_116228)
ABV: 
AGABI2DRAFT135141(AGABI2DRAFT_135141)
CPUT: 
SLA: 
WSE: 
WIC: 
PFP: 
MGL: 
PGR: 
MLR: 
EHE: 
ERO: 
MBR: 
SRE: 
DDI: 
DPP: 
DFA: 
DFA_07623(cnbA)
EHI: 
EHI_106670(217.t00005)
EDI: 
EIV: 
ACAN: 
PFA: 
PFH: 
PYO: 
PCB: 
PBE: 
PKN: 
PVX: 
PCY: 
CPV: 
CHO: 
TGO: 
TET: 
PTM: 
TPS: 
AAF: 
PIF: 
PSOJ: 
SPAR: 
EHX: 
GTT: 
TBR: 
TCR: 
LMA: 
LIF: 
LDO: 
LMI: 
LBZ: 
NGR: 
TVA: 
GLA: 
CALO: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Rusnak F, Mertz P
  Title
Calcineurin: form and function.
  Journal
Physiol Rev 80:1483-521 (2000)

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