KEGG   ORTHOLOGY: K06461Help
Entry
K06461                      KO                                     

Name
ITGAM
Definition
integrin alpha M
Pathway
Rap1 signaling pathway
Phagosome
Cell adhesion molecules (CAMs)
Hematopoietic cell lineage
Leukocyte transendothelial migration
Regulation of actin cytoskeleton
Pertussis
Legionellosis
Leishmaniasis
Amoebiasis
Staphylococcus aureus infection
Tuberculosis
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K06461  ITGAM; integrin alpha M
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    K06461  ITGAM; integrin alpha M
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K06461  ITGAM; integrin alpha M
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06461  ITGAM; integrin alpha M
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K06461  ITGAM; integrin alpha M
   04670 Leukocyte transendothelial migration
    K06461  ITGAM; integrin alpha M
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K06461  ITGAM; integrin alpha M
  Infectious diseases
   05133 Pertussis
    K06461  ITGAM; integrin alpha M
   05134 Legionellosis
    K06461  ITGAM; integrin alpha M
   05150 Staphylococcus aureus infection
    K06461  ITGAM; integrin alpha M
   05152 Tuberculosis
    K06461  ITGAM; integrin alpha M
   05146 Amoebiasis
    K06461  ITGAM; integrin alpha M
   05140 Leishmaniasis
    K06461  ITGAM; integrin alpha M
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K06461  ITGAM; integrin alpha M
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Immune system
   ICAM family
    ICAM1; intercellular adhesion molecule 1
     CR3, Mac-1
      K06461 ITGAM; integrin alpha M
    ICAM2; intercellular adhesion molecule 2
     CR3, Mac-1
      K06461 ITGAM; integrin alpha M
  Neural system
   N/0 subfamily
    THY1, CD90; Thy-1 cell surface antigen
     CR3, Mac-1
      K06461 ITGAM; integrin alpha M
  Others
   VCAM1; vascular cell adhesion molecule 1
    CR3, Mac-1
     K06461 ITGAM; integrin alpha M
   ICAM4; intercellular adhesion molecule 4
    CR3, Mac-1
     K06461 ITGAM; integrin alpha M
   JAM3; junctional adhesional molecule 3
    CR3, Mac-1
     K06461 ITGAM; integrin alpha M
 3. Selectin Family
  SELE; selectin, endothelial cell
   CR3, Mac-1
    K06461 ITGAM; integrin alpha M
 7. Others
  TNFSF5, CD40L; tumor necrosis factor (ligand) superfamily, member 5
   CR3, Mac-1
    K06461 ITGAM; integrin alpha M
  CD209; CD209 antigen
   CR3, Mac-1
    K06461 ITGAM; integrin alpha M
Cellular antigens [BR:ko04090]
 Proteins
  K06461  CD11b, ITGAM; integrin, alpha M
Heparan sulfate/heparin binding proteins [BR:ko00536]
 Adhesion molecules of cell surface
  K06461  ITGAM; integrin alpha M
BRITE hierarchy
Genes
HSA: 
3684(ITGAM)
PTR: 
454069(ITGAM)
PPS: 
100992002(ITGAM)
GGO: 
101135400(ITGAM)
PON: 
100439660(ITGAM)
MCF: 
MMU: 
16409(Itgam)
RNO: 
25021(Itgam)
CGE: 
100758889(Itgam)
HGL: 
101719288(Itgam)
TUP: 
102483623(ITGAM)
CFA: 
489928(ITGAM)
AML: 
100475340(ITGAM)
FCA: 
101087957(ITGAM)
PTG: 
102966486(ITGAM)
BTA: 
407124(ITGAM)
BOM: 
102270519(ITGAM)
PHD: 
102328883(ITGAM)
CHX: 
102180100(ITGAM)
SSC: 
397459(ITGAM)
CFR: 
102513083(ITGAM)
BACU: 
103004729(ITGAM)
LVE: 
103073578(ITGAM)
ECB: 
100064803(ITGAM)
MYB: 
102257478(ITGAM)
MYD: 
PALE: 
102889241(ITGAM)
MDO: 
OAA: 
100085462(ITGAM)
ACS: 
100556984(itgam)
XTR: 
TRU: 
OLA: 
XMA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
van der Flier A, Sonnenberg A.
  Title
Function and interactions of integrins.
  Journal
Cell Tissue Res 305:285-98 (2001)
Reference
  Authors
Barczyk M, Carracedo S, Gullberg D
  Title
Integrins.
  Journal
Cell Tissue Res 339:269-80 (2010)

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