KEGG   ORTHOLOGY: K06480Help
Entry
K06480                      KO                                     
Name
ITGA1
Definition
integrin alpha 1
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Hematopoietic cell lineage
Regulation of actin cytoskeleton
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K06480  ITGA1; integrin alpha 1
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06480  ITGA1; integrin alpha 1
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K06480  ITGA1; integrin alpha 1
  Cell communication
   04510 Focal adhesion
    K06480  ITGA1; integrin alpha 1
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K06480  ITGA1; integrin alpha 1
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K06480  ITGA1; integrin alpha 1
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06480  ITGA1; integrin alpha 1
   05414 Dilated cardiomyopathy (DCM)
    K06480  ITGA1; integrin alpha 1
Cellular antigens [BR:ko04090]
 Proteins
  K06480  CD49a, ITGA1; integrin, alpha 1
BRITE hierarchy
Genes
HSA: 
3672(ITGA1)
PTR: 
461880(ITGA1)
PPS: 
100978092(ITGA1)
GGO: 
101128466(ITGA1)
PON: 
100439453(ITGA1)
MCC: 
703456(ITGA1)
MMU: 
109700(Itga1)
RNO: 
25118(Itga1)
CFA: 
489210(ITGA1)
AML: 
100476147(ITGA1)
FCA: 
101089743(ITGA1)
BTA: 
535951(ITGA1)
SSC: 
100512142
ECB: 
100063434(ITGA1)
MDO: 
100031492(ITGA1)
SHR: 
100928961 100929969
GGA: 
395951(ITGA1)
TGU: 
100224251(ITGA1)
ACS: 
100564502
XTR: 
100492880(itga1)
DRE: 
570868(itga1)
TRU: 
101078427
OLA: 
101159685
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
van der Flier A, Sonnenberg A.
  Title
Function and interactions of integrins.
  Journal
Cell Tissue Res 305:285-98 (2001)
Reference
  Authors
Barczyk M, Carracedo S, Gullberg D
  Title
Integrins.
  Journal
Cell Tissue Res 339:269-80 (2010)
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