KEGG   ORTHOLOGY: K06642Help
Entry
K06642                      KO                                     

Name
PRKDC
Definition
DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
Pathway
Non-homologous end-joining
Cell cycle
Module
M00297  
DNA-PK complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Replication and repair
   03450 Non-homologous end-joining
    K06642  PRKDC; DNA-dependent protein kinase catalytic subunit
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K06642  PRKDC; DNA-dependent protein kinase catalytic subunit
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Repair system
    M00297  DNA-PK complex
     K06642  PRKDC; DNA-dependent protein kinase catalytic subunit
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K06642  PRKDC; DNA-dependent protein kinase catalytic subunit
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: Atypical group
  PIKK family [OT]
   K06642  PRKDC; DNA-dependent protein kinase catalytic subunit
DNA replication proteins [BR:ko03032]
 Eukaryotic Type
  DNA Replication Termination Factors
   Other telomere regulation proteins
    Others
     K06642  PRKDC; DNA-dependent protein kinase catalytic subunit
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    DNA-PK complex
     K06642  PRKDC; DNA-dependent protein kinase catalytic subunit
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5591(PRKDC)
PTR: 
464165(PRKDC)
PPS: 
100981342(PRKDC)
GGO: 
101128261(PRKDC)
PON: 
100460398(PRKDC)
NLE: 
MCC: 
708029(PRKDC)
MCF: 
102119406(PRKDC)
CSAB: 
103236758(PRKDC)
RRO: 
104657634(PRKDC)
RBB: 
108535350(PRKDC)
CJC: 
100399020(PRKDC)
SBQ: 
101053589(PRKDC)
MMU: 
19090(Prkdc)
RNO: 
360748(Prkdc)
CGE: 
100770748(Prkdc)
NGI: 
HGL: 
101722248(Prkdc)
CCAN: 
OCU: 
100125348(PRKDC)
TUP: 
102497296(PRKDC)
CFA: 
474176(PRKDC)
AML: 
100472045(PRKDC)
UMR: 
103677407(PRKDC)
ORO: 
101380166(PRKDC)
FCA: 
101088389(PRKDC)
PTG: 
102960352(PRKDC)
AJU: 
106982122(PRKDC)
BTA: 
512740(PRKDC)
BOM: 
102285992(PRKDC)
BIU: 
109568449(PRKDC)
PHD: 
CHX: 
102171625(PRKDC)
OAS: 
101111377(PRKDC)
SSC: 
100156379(PRKDC)
CFR: 
102519846(PRKDC)
CDK: 
BACU: 
103019606(PRKDC)
LVE: 
103090600(PRKDC)
ECB: 
791233(PRKDC)
EPZ: 
EAI: 
MYB: 
MYD: 
102770810(PRKDC)
HAI: 
109392680(PRKDC)
RSS: 
PALE: 
102895801(PRKDC)
LAV: 
100667300(PRKDC)
TMU: 
MDO: 
100030684(PRKDC)
SHR: 
100915132(PRKDC)
OAA: 
100084470(PRKDC)
GGA: 
395376(PRKDC)
MGP: 
100546550(PRKDC)
CJO: 
107310139(PRKDC)
APLA: 
101804792(PRKDC)
ACYG: 
106038417(PRKDC)
TGU: 
100224961(PRKDC)
GFR: 
102042450(PRKDC)
FAB: 
101819416(PRKDC)
PHI: 
102108488(PRKDC)
PMAJ: 
107200430(PRKDC)
CCW: 
104690434(PRKDC)
FPG: 
101914535(PRKDC)
FCH: 
102045681(PRKDC)
CLV: 
EGZ: 
AAM: 
106494392(PRKDC)
ASN: 
102387673(PRKDC)
AMJ: 
102575311(PRKDC)
PSS: 
102454928(PRKDC)
CMY: 
102937565(PRKDC)
CPIC: 
101936824(PRKDC)
ACS: 
100562493(prkdc)
PVT: 
110077653(PRKDC)
PBI: 
GJA: 
107122359(PRKDC)
XLA: 
373602(prkdc.L)
XTR: 
100488663(prkdc)
NPR: 
108792226(PRKDC)
DRE: 
562283(prkdc)
SRX: 
SANH: 
SGH: 
107591017(prkdc)
CCAR: 
IPU: 
108268160(prkdc)
AMEX: 
103028565(prkdc)
TRU: 
101073073(prkdc)
TNG: 
LCO: 
104928964(prkdc)
NCC: 
104943222(prkdc)
MZE: 
101484851(prkdc)
OLA: 
101171206(prkdc)
XMA: 
102221760(prkdc)
PRET: 
103482327(prkdc)
CSEM: 
103377075(prkdc)
LCF: 
108898307(prkdc)
HCQ: 
109507813(prkdc)
BPEC: 
110165311(prkdc)
SASA: 
106579558(prkdc)
ELS: 
105019560(prkdc)
SFM: 
108919710(prkdc)
LCM: 
102352949(PRKDC)
CMK: 
103175370(prkdc)
BFO: 
CIN: 
100185020(prkdc)
SPU: 
APLC: 
SKO: 
AGA: 
CQU: 
AME: 
552548(GB11176)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
API: 
DNX: 
ZNE: 
FCD: 
DPX: 
ISC: 
TSP: 
HRO: 
LGI: 
CRG: 
MYI: 
OBI: 
LAK: 
OVI: 
NVE: 
EPA: 
ADF: 
HMG: 
100210864(prkdc)
TAD: 
AQU: 
SMO: 
PPP: 
VCN: 
OLU: 
OTA: 
BPG: 
MIS: 
MPP: 
CSL: 
MBR: 
SRE: 
DDI: 
DDB_G0281167(dnapkcs)
DPP: 
DFA: 
DFA_11411(dnapkcs)
TET: 
PTM: 
PIF: 
PSOJ: 
SPAR: 
GTT: 
TCR: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Soubeyrand S, Pope L, Pakuts B, Hache RJ
  Title
Threonines 2638/2647 in DNA-PK are essential for cellular resistance to ionizing radiation.
  Journal
Cancer Res 63:1198-201 (2003)
  Sequence
[hsa:5591]

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