KEGG   ORTHOLOGY: K06752Help
Entry
K06752                      KO                                     
Name
MHC2
Definition
major histocompatibility complex, class II
Pathway
Phagosome
Cell adhesion molecules (CAMs)
Antigen processing and presentation
Intestinal immune network for IgA production
Type I diabetes mellitus
Leishmaniasis
Toxoplasmosis
Staphylococcus aureus infection
Tuberculosis
Influenza A
HTLV-I infection
Herpes simplex infection
Asthma
Autoimmune thyroid disease
Systemic lupus erythematosus
Rheumatoid arthritis
Allograft rejection
Graft-versus-host disease
Viral myocarditis
Disease
H00079  
Asthma
H00080  
Systemic lupus erythematosus
H00081  
Hashimoto's thyroiditis
H00082  
Graves' disease
H00083  
Allograft rejection
H00294  
Dilated cardiomyopathy (DCM)
H00295  
Viral myocarditis
H00342  
Tuberculosis
H00408  
Type I diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    K06752  MHC2; major histocompatibility complex, class II
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K06752  MHC2; major histocompatibility complex, class II
 Organismal Systems
  Immune system
   04612 Antigen processing and presentation
    K06752  MHC2; major histocompatibility complex, class II
   04672 Intestinal immune network for IgA production
    K06752  MHC2; major histocompatibility complex, class II
 Human Diseases
  Immune diseases
   05310 Asthma
    K06752  MHC2; major histocompatibility complex, class II
   05322 Systemic lupus erythematosus
    K06752  MHC2; major histocompatibility complex, class II
   05323 Rheumatoid arthritis
    K06752  MHC2; major histocompatibility complex, class II
   05320 Autoimmune thyroid disease
    K06752  MHC2; major histocompatibility complex, class II
   05330 Allograft rejection
    K06752  MHC2; major histocompatibility complex, class II
   05332 Graft-versus-host disease
    K06752  MHC2; major histocompatibility complex, class II
  Cardiovascular diseases
   05416 Viral myocarditis
    K06752  MHC2; major histocompatibility complex, class II
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K06752  MHC2; major histocompatibility complex, class II
  Infectious diseases
   05150 Staphylococcus aureus infection
    K06752  MHC2; major histocompatibility complex, class II
   05152 Tuberculosis
    K06752  MHC2; major histocompatibility complex, class II
   05166 HTLV-I infection
    K06752  MHC2; major histocompatibility complex, class II
   05164 Influenza A
    K06752  MHC2; major histocompatibility complex, class II
   05168 Herpes simplex infection
    K06752  MHC2; major histocompatibility complex, class II
   05145 Toxoplasmosis
    K06752  MHC2; major histocompatibility complex, class II
   05140 Leishmaniasis
    K06752  MHC2; major histocompatibility complex, class II
Cell adhesion molecules and their ligands [BR:ko04516]
 1. Immunoglobulin Superfamily
  Immune system
   Others
    CD4; CD4 antigen
     K06752 MHC2; major histocompatibility complex, class II
    LAG3; lymphocyte-activation gene 3 protein
     K06752 MHC2; major histocompatibility complex, class II
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
100507709 100507714 100509457 101060835 3108(HLA-DMA) 3109(HLA-DMB) 3111(HLA-DOA) 3112(HLA-DOB) 3113(HLA-DPA1) 3115(HLA-DPB1) 3117(HLA-DQA1) 3118(HLA-DQA2) 3119(HLA-DQB1) 3122(HLA-DRA) 3123(HLA-DRB1) 3125(HLA-DRB3) 3126(HLA-DRB4) 3127(HLA-DRB5)
PTR: 
100608816(MAMU-DMA) 100616520 449592(PATR-DMB) 462591(PATR-DRA) 462592(PATR-DRB5) 462594(PATR-DQB1) 462598(PATR-DPA1) 462599(PATR-DPB1) 471974(PATR-DQA1) 471976(PATR-DQA2) 471977(PATR-DOB) 471979
PPS: 
GGO: 
PON: 
MCC: 
100187587(MAMU-DRA) 100428228(MAMU-DRB5) 100429857(MAMU-DMB) 692100(MAMU-DRB1) 705588 716823(MAMU-DQB1) 717623(HLA-DQA1) 717702(MAMU-DOB) 717870(MAMU-DMA) 717947(MAMU-DOA) 717969(MAMU-DPB) 717992(MAMU-DPA) 720582(MAMU-DQA1)
MMU: 
100504404(H2-Ea-ps) 14960(H2-Aa) 14961(H2-Ab1) 14969(H2-Eb1) 14998(H2-DMa) 14999(H2-DMb1) 15000(H2-DMb2) 15001(H2-Oa) 15002(H2-Ob)
RNO: 
100909593 100909630 100911800 24984(RT1-DOa) 24986(RT1-Ha) 294269(RT1-Da) 294270(RT1-Db1) 294273(RT1-DMb) 294274(RT1-DMa) 309621(RT1-Ba) 309622(RT1-Bb) 365542(RT1-DOb) 688090(RT1-Bb)
CFA: 
100856137 474860(HLA-DRB1) 474861(DLA-DQA1) 474862(DLA-DQB1) 474869(DLA-DOA) 481731(DLA-DRA) 481732(DLA-DMA) 607786(DLA-DOB) 607827(DLA-DMB)
AML: 
FCA: 
100169654(SLC26A3) 100169655(FECA-DRB) 101082653 101082906 101084108 101084962 101090265 101090518 101090771 101098301
BTA: 
100848815 282490(BOLA-DMA) 282491(BOLA-DMB) 282493(BOLA-DOB) 282494(BOLA-DQA5) 282495(BOLA-DQB) 282498(BOLA-DYB) 282530(BOLA-DRB3) 282534(BOLA-DQA1) 282535(BOLA-DQA2) 506214(BOLA-DRA) 525727(BOLA-DOA) 539241(BLA-DQB) 790858(LA-DQB)
SSC: 
100037921(SLA-DQB1) 100135040(SLA-DRA) 100135049(SLA-DOB) 100135050(SLA-DMB) 100153386(SLA-DRB1) 100153387(SLA-DQA1) 100157996(SLA-DOA) 445528(SLA-DMA)
ECB: 
100051944(DRA) 100052006(DRB) 100052125(DQA) 100052184(DQB) 100052249(DQA) 100052310(DRB) 100052364(DRB) 100060531 100060770 100060996 100061035 100061127
MDO: 
100024589 100025990 100026007 100026088 100026858 100026891 554228(MODO-DAB1)
SHR: 
100917964 100918485 100923003 100925533 100925801
OAA: 
100079322(ORAN-DRA) 100088072
GGA: 
417050(BMA1) 417051(B-MA2) 425256 693256(BLB2) 724083(BLB1)
MGP: 
100547088 100549648
TGU: 
100229282
ACS: 
100552026 100552818 100558183
XLA: 
379662(MGC69040) 399001(mhc2a) 495177(hla-dra) 495209 495464 733414
XTR: 
100127727(hla-dqa1) 100145090 100495183 100495336 734125(hla-drb1)
DRE: 
30762(mhc2dab) 30763(mhc2dcb) 30764(mhc2deb) 30783(mhc2a) 335509(a1) 368614(si:dz48c11.3) 368615(MHCII) 368816(MHCII) 368877(si:dz266f07.1) 368878(MHCII) 571282 654336
TRU: 
101071249 101077981
OLA: 
101156150 101156391 101160212 101160459 101163459 101170703
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Handunnetthi L, Ramagopalan SV, Ebers GC, Knight JC
  Title
Regulation of major histocompatibility complex class II gene expression, genetic  variation and disease.
  Journal
Genes Immun 11:99-112 (2010)
DBGET integrated database retrieval system