KEGG   ORTHOLOGY: K07205Help
Entry
K07205                      KO                                     

Name
EIF4EBP1
Definition
eukaryotic translation initiation factor 4E binding protein 1
Pathway
RNA transport
ErbB signaling pathway
HIF-1 signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Insulin signaling pathway
Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Translation
   03013 RNA transport
    K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
   04066 HIF-1 signaling pathway
    K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
   04151 PI3K-Akt signaling pathway
    K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
   04152 AMPK signaling pathway
    K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
   04150 mTOR signaling pathway
    K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
 Human Diseases
  Cancers
   05221 Acute myeloid leukemia
    K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
1978(EIF4EBP1)
PTR: 
464114(EIF4EBP1)
PPS: 
100972246(EIF4EBP1)
GGO: 
101145454(EIF4EBP1)
PON: 
100455169(EIF4EBP1)
MCC: 
703628(EIF4EBP1)
MCF: 
102132583(EIF4EBP1)
MMU: 
13685(Eif4ebp1)
RNO: 
116636(Eif4ebp1)
CGE: 
100769654(Eif4ebp1)
HGL: 
101710614(Eif4ebp1)
TUP: 
102494657(EIF4EBP1)
CFA: 
475590(EIF4EBP1)
AML: 
FCA: 
101088571(EIF4EBP1)
PTG: 
102961839(EIF4EBP1)
BTA: 
509613(EIF4EBP1)
BOM: 
102278368(EIF4EBP1)
PHD: 
102341604(EIF4EBP1)
CHX: 
100861234(4E-BP1)
OAS: 
101111426(EIF4EBP1)
SSC: 
100627508(EIF4EBP1)
CFR: 
102520195(EIF4EBP1)
BACU: 
103018352(EIF4EBP1)
LVE: 
103074746(EIF4EBP1)
ECB: 
100057875(EIF4EBP1)
MYB: 
MYD: 
PALE: 
102881655(EIF4EBP1)
MDO: 
100029774(EIF4EBP1)
SHR: 
100917643(EIF4EBP1)
OAA: 
100084037(EIF4EBP1)
GGA: 
426773(EIF4EBP1)
MGP: 
TGU: 
PHI: 
102105579(EIF4EBP1)
APLA: 
101798286(EIF4EBP1)
FPG: 
101918789(EIF4EBP1)
FCH: 
102047520(EIF4EBP1)
CLV: 
102083572(EIF4EBP1)
ASN: 
AMJ: 
PSS: 
102459901(EIF4EBP1)
CMY: 
102944935(EIF4EBP1)
ACS: 
PBI: 
103063177(EIF4EBP1)
TRU: 
MZE: 
OLA: 
XMA: 
CMK: 
103190311(eif4ebp1)
SPU: 
752411(4e-bp)
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsim_GD23237(Dsim_Thor)
DWI: 
DYA: 
Dyak_GE18239(Dyak_Thor)
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
725039(GB10069)
NVI: 
TCA: 
BMOR: 
PHU: 
ISC: 
NVE: 
WSE: 
DDI: 
DPP: 
DFA: 
DFA_02929(febA)
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Tsukiyama-Kohara K, Poulin F, Kohara M, DeMaria CT, Cheng A, Wu Z, Gingras AC, Katsume A, Elchebly M, Spiegelman BM, Harper ME, Tremblay ML, Sonenberg N
  Title
Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.
  Journal
Nat Med 7:1128-32 (2001)
  Sequence
[mmu:13685]
Reference
  Authors
Yanagiya A, Suyama E, Adachi H, Svitkin YV, Aza-Blanc P, Imataka H, Mikami S, Martineau Y, Ronai ZA, Sonenberg N
  Title
Translational homeostasis via the mRNA cap-binding protein, eIF4E.
  Journal
Mol Cell 46:847-58 (2012)
  Sequence
[hsa:1978]

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