K07418                      KO                                     

cytochrome P450 family 2 subfamily J [EC:]
ko00590  Arachidonic acid metabolism
ko00591  Linoleic acid metabolism
ko01100  Metabolic pathways
ko04212  Longevity regulating pathway - worm
ko04726  Serotonergic synapse
ko04750  Inflammatory mediator regulation of TRP channels
ko04913  Ovarian steroidogenesis
KEGG Orthology (KO) [BR:ko00001]
  Lipid metabolism
   00590 Arachidonic acid metabolism
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
   00591 Linoleic acid metabolism
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
 Organismal Systems
  Endocrine system
   04913 Ovarian Steroidogenesis
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
  Nervous system
   04726 Serotonergic synapse
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
   04212 Longevity regulating pathway - worm
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor  unspecific monooxygenase
     K07418  CYP2J; cytochrome P450 family 2 subfamily J
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K07418  CYP2J; cytochrome P450 family 2 subfamily J
BRITE hierarchy
Other DBs
RN: R07042 R07043 R07044 R07045 R07046 R07048 R07050 R07051 R07052 R07055 R07056
HSA: 1573(CYP2J2)
PTR: 456896(CYP2J2)
PPS: 100984148
GGO: 101148349
PON: 100447634
NLE: 100589053
MCC: 693631
MCF: 102119662(CYP2J2)
CSAB: 103224719(CYP2J2)
RRO: 104668045
RBB: 108532916
CJC: 100397287(CYP2J2)
SBQ: 101041470
MMU: 100066(Cyp2j11) 13109(Cyp2j5) 13110(Cyp2j6) 230459(Cyp2j13) 242546(Cyp2j12) 665095(Cyp2j8) 74519(Cyp2j9)
RNO: 100912642 313373(Cyp2j10) 313375(Cyp2j3) 502969(Cyp2j16) 65210(Cyp2j4)
OCU: 100301544(CYP2J1)
CFA: 610195(CYP2J2)
AML: 100482335
UMR: 103663082
ORO: 101382939
FCA: 101097746
PTG: 102958105
AJU: 106974984
BTA: 510406(CYP2J2) 511936 521656 530929
LVE: 103072875
OOR: 101287985
ECB: 100067247
EAI: 106833456
MYB: 102259820
MYD: 102765527
PALE: 102885276
TMU: 101350163
OAA: 100087745
GGA: 424676(CYP2J23) 424677(CYP2J22) 424678(CYP2J20) 424729(CYP2J19)
AMJ: 102557714(CYP2P10)
CMY: 102940076(CYP2J19)
DRE: 100034366(cyp2p8) 100034406(cyp2p7) 393108(cyp2p6) 393592(cyp2p9) 399485(cyp2p10) 797309(cyp2j20)
IPU: 108276005
MDE: 101889924
CFO: 105251497
LHU: 105679943
TCA: 654979(CYP303A1)
PMAC: 106720643
PXY: 105384566
ZNE: 110841127
CEL: CELE_T13C5.1(daf-9)
CBR: CBG10440 CBG14860(Cbr-daf-9)
BMY: Bm1_42095
EPA: 110234629
ADF: 107343620
CIT: 102618410
TCC: 18599056
GMX: 100819247
VRA: 106766357
VAR: 108335141
CAM: 101501717 101506258(cyp81E2)
LJA: Lj0g3v0283519.1(Lj0g3v0283519.1) Lj2g3v1925640.1(Lj2g3v1925640.1)
PXB: 103960984
VVI: 100250924
NSY: 104241233
SOE: 110802387
DOSA: Os02t0185200-01(Os02g0185200)
OBR: 102705222
BDI: 100824609
ATS: 109732603(LOC109732603) 109752591(LOC109752591) 109760367(LOC109760367) 109782632(LOC109782632) 109784156(LOC109784156) 109784258(LOC109784258)
EGU: 105041571
DFA: DFA_00135(CYP520A1) DFA_00936 DFA_03144(GP138_ps1) DFA_03145(CYP508A4) DFA_03148 DFA_03460(CYP508C1) DFA_03710 DFA_04220 DFA_07282(CYP555A1) DFA_07666(CYP521A1) DFA_10420 DFA_10460(CYP520B1) DFA_10470 DFA_12091(CYP516A1)
 » show all
Wu S, Moomaw CR, Tomer KB, Falck JR, Zeldin DC
Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart.
J Biol Chem 271:3460-8 (1996)
Iliff JJ, Jia J, Nelson J, Goyagi T, Klaus J, Alkayed NJ
Epoxyeicosanoid signaling in CNS function and disease.
Prostaglandins Other Lipid Mediat 91:68-84 (2010)
Scarborough PE, Ma J, Qu W, Zeldin DC
P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues.
Drug Metab Rev 31:205-34 (1999)

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