KEGG   ORTHOLOGY: K07514Help
Entry
K07514                      KO                                     

Name
EHHADH
Definition
enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
Pathway
Fatty acid degradation
Valine, leucine and isoleucine degradation
Lysine degradation
Benzoate degradation
Tryptophan metabolism
beta-Alanine metabolism
Aminobenzoate degradation
Propanoate metabolism
Butanoate metabolism
Caprolactam degradation
Carbon metabolism
Fatty acid metabolism
PPAR signaling pathway
Peroxisome
Module
M00013  
Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA
M00032  
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
M00087  
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
   01212 Fatty acid metabolism
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
  Carbohydrate metabolism
   00640 Propanoate metabolism
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
   00650 Butanoate metabolism
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
  Lipid metabolism
   00071 Fatty acid degradation
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
  Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
   00310 Lysine degradation
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
   00380 Tryptophan metabolism
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
  Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
   00627 Aminobenzoate degradation
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
   00930 Caprolactam degradation
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
 Cellular Processes
  Transport and catabolism
   04146 Peroxisome
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
 Organismal Systems
  Endocrine system
   03320 PPAR signaling pathway
    K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Other carbohydrate metabolism
    M00013  Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA
     K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
   Fatty acid metabolism
    M00087  beta-Oxidation
     K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
  Nucleotide and amino acid metabolism
   Lysine metabolism
    M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
     K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.35  3-hydroxyacyl-CoA dehydrogenase
     K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.17  enoyl-CoA hydratase
     K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.8  dodecenoyl-CoA isomerase
     K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase
BRITE hierarchy
Other DBs
Genes
HSA: 
1962(EHHADH)
PTR: 
460996(EHHADH)
PPS: 
100985141(EHHADH)
GGO: 
PON: 
100174685(EHHADH)
MCC: 
701193(EHHADH)
MCF: 
102118537(EHHADH)
MMU: 
74147(Ehhadh)
RNO: 
171142(Ehhadh)
CGE: 
HGL: 
101699730(Ehhadh)
TUP: 
102502891(EHHADH)
CFA: 
488110(EHHADH)
AML: 
FCA: 
101083876(EHHADH)
PTG: 
102965690(EHHADH)
BTA: 
518852(EHHADH)
BOM: 
102285943(EHHADH)
PHD: 
102342190(EHHADH)
CHX: 
102179598(EHHADH)
SSC: 
448846(EHHADH)
CFR: 
102519802(EHHADH)
ECB: 
100067714(EHHADH)
MYB: 
102240784(EHHADH)
MYD: 
102771761(EHHADH)
PALE: 
102880064(EHHADH)
SHR: 
100913272(EHHADH)
OAA: 
100082172(EHHADH)
GGA: 
424877(EHHADH)
MGP: 
100551164(EHHADH)
TGU: 
100218671(EHHADH) 100229171(EHHADH)
FAB: 
101818793(EHHADH)
PHI: 
102112202(EHHADH)
APLA: 
101795970(EHHADH)
FPG: 
101918474(EHHADH)
FCH: 
102057870(EHHADH)
CLV: 
102091542(EHHADH)
ASN: 
102381971(EHHADH)
PSS: 
102453335(EHHADH)
CMY: 
102939101(EHHADH)
ACS: 
100558466(ehhadh)
XTR: 
100216115(ehhadh)
DRE: 
100000859(ehhadh)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102356308(EHHADH)
BFO: 
CIN: 
TAD: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL
  Title
Regulation of cellular metabolism by protein lysine acetylation.
  Journal
Science 327:1000-4 (2010)

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