KEGG   ORTHOLOGY: K07827Help
Entry
K07827                      KO                                     

Name
KRAS, KRAS2
Definition
GTPase KRas
Pathway
MAPK signaling pathway
ErbB signaling pathway
MAPK signaling pathway - fly
Ras signaling pathway
Rap1 signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Axon guidance
VEGF signaling pathway
Tight junction
Gap junction
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Long-term potentiation
Neurotrophin signaling pathway
Cholinergic synapse
Serotonergic synapse
Long-term depression
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Aldosterone-regulated sodium reabsorption
Alcoholism
Hepatitis C
Hepatitis B
HTLV-I infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
MicroRNAs in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Thyroid cancer
Melanoma
Bladder cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Disease
H00003  
Acute myeloid leukemia (AML)
H00010  
Multiple myeloma
H00014  
Non-small cell lung cancer
H00016  
Oral cancer
H00018  
Gastric cancer
H00019  
Pancreatic cancer
H00020  
Colorectal cancer
H00026  
Endometrial Cancer
H00027  
Ovarian cancer
H00030  
Cervical cancer
H00032  
Thyroid cancer
H00040  
Squamous cell carcinoma
H00041  
Kaposi's sarcoma
H00046  
Cholangiocarcinoma
H00047  
Gallbladder cancer
H00048  
Hepatocellular carcinoma
H00458  
Craniosynostosis
H00523  
Noonan syndrome and related disorders
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04015 Rap1 signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04010 MAPK signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04013 MAPK signaling pathway - fly
    K07827  KRAS, KRAS2; GTPase KRas
   04012 ErbB signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04370 VEGF signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04068 FoxO signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04151 PI3K-Akt signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K07827  KRAS, KRAS2; GTPase KRas
  Cell communication
   04530 Tight junction
    K07827  KRAS, KRAS2; GTPase KRas
   04540 Gap junction
    K07827  KRAS, KRAS2; GTPase KRas
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07827  KRAS, KRAS2; GTPase KRas
   04660 T cell receptor signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04662 B cell receptor signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04664 Fc epsilon RI signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04062 Chemokine signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
  Endocrine system
   04910 Insulin signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04912 GnRH signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04915 Estrogen signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04914 Progesterone-mediated oocyte maturation
    K07827  KRAS, KRAS2; GTPase KRas
   04917 Prolactin signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04921 Oxytocin signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04919 Thyroid hormone signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04916 Melanogenesis
    K07827  KRAS, KRAS2; GTPase KRas
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K07827  KRAS, KRAS2; GTPase KRas
  Nervous system
   04725 Cholinergic synapse
    K07827  KRAS, KRAS2; GTPase KRas
   04726 Serotonergic synapse
    K07827  KRAS, KRAS2; GTPase KRas
   04720 Long-term potentiation
    K07827  KRAS, KRAS2; GTPase KRas
   04730 Long-term depression
    K07827  KRAS, KRAS2; GTPase KRas
   04722 Neurotrophin signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
  Development
   04320 Dorso-ventral axis formation
    K07827  KRAS, KRAS2; GTPase KRas
   04360 Axon guidance
    K07827  KRAS, KRAS2; GTPase KRas
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05206 MicroRNAs in cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05205 Proteoglycans in cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05203 Viral carcinogenesis
    K07827  KRAS, KRAS2; GTPase KRas
   05210 Colorectal cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05212 Pancreatic cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05214 Glioma
    K07827  KRAS, KRAS2; GTPase KRas
   05216 Thyroid cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05221 Acute myeloid leukemia
    K07827  KRAS, KRAS2; GTPase KRas
   05220 Chronic myeloid leukemia
    K07827  KRAS, KRAS2; GTPase KRas
   05218 Melanoma
    K07827  KRAS, KRAS2; GTPase KRas
   05211 Renal cell carcinoma
    K07827  KRAS, KRAS2; GTPase KRas
   05219 Bladder cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05215 Prostate cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05213 Endometrial cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05223 Non-small cell lung cancer
    K07827  KRAS, KRAS2; GTPase KRas
  Substance dependence
   05034 Alcoholism
    K07827  KRAS, KRAS2; GTPase KRas
  Infectious diseases
   05166 HTLV-I infection
    K07827  KRAS, KRAS2; GTPase KRas
   05161 Hepatitis B
    K07827  KRAS, KRAS2; GTPase KRas
   05160 Hepatitis C
    K07827  KRAS, KRAS2; GTPase KRas
GTP-binding proteins [BR:ko04031]
 Small (Monomeric) G-proteins
  Ras Family
   Ras [OT]
    K07827  KRAS, KRAS2; GTPase KRas
BRITE hierarchy
Genes
HSA: 
3845(KRAS)
PTR: 
473387(KRAS)
PPS: 
100990801(KRAS)
GGO: 
101144039(KRAS)
PON: 
MCC: 
707977(KRAS)
MCF: 
102131483(KRAS)
MMU: 
16653(Kras)
RNO: 
24525(Kras)
CGE: 
100763178(Kras)
HGL: 
101718997(Kras)
TUP: 
102500069(KRAS)
CFA: 
403871(KRAS)
AML: 
FCA: 
751104(K-RAS)
PTG: 
102957350(KRAS)
BTA: 
541140(KRAS)
BOM: 
102286500(KRAS)
PHD: 
102323857(KRAS)
CHX: 
102172519(KRAS)
SSC: 
100518251(KRAS)
CFR: 
102516372(KRAS)
BACU: 
103015457(KRAS)
LVE: 
103077579(KRAS)
ECB: 
100064473(KRAS)
MYB: 
102244940(KRAS)
MYD: 
102762284(KRAS)
PALE: 
102895590(KRAS)
MDO: 
554186(KRAS)
SHR: 
OAA: 
100085430(KRAS)
GGA: 
418207(KRAS)
MGP: 
100151750(KRAS)
TGU: 
100227892(KRAS)
FAB: 
101809651(KRAS)
PHI: 
102112893(KRAS)
APLA: 
101793538(KRAS)
FPG: 
101917762(KRAS)
FCH: 
102052019(KRAS)
CLV: 
102096076(KRAS)
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
100505423 373672(kras-a) 397771(kras-b) 399470(ralb)
XTR: 
DRE: 
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
SPU: 
DME: 
Dmel_CG9375(Ras85D)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsim_GD20791(Dsim_Ras85D)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
Dvir_GJ23844(Dvir_Ras1)
AGA: 
AAG: 
CQU: 
AME: 
410812(GB12556)
NVI: 
TCA: 
BMOR: 
692520(Ras1)
API: 
PHU: 
ISC: 
CEL: 
CELE_ZK792.6(let-60)
CBR: 
CBG06092(Cbr-let-60)
BMY: 
LOA: 
TSP: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
SCE: 
YNL098C(RAS2) YOR101W(RAS1)
AGO: 
ERC: 
KLA: 
LTH: 
PPA: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0B06850(NCAS0B06850)
NDI: 
NDAI_0B04180(NDAI0B04180)
TPF: 
TPHA_0B03000(TPHA0B03000)
TBL: 
TBLA_0B01410(TBLA0B01410) TBLA_0B01750(TBLA0B01750)
TDL: 
TDEL_0F01360(TDEL0F01360)
KAF: 
KAFR_0D02040(KAFR0D02040) KAFR_0J01970(KAFR0J01970)
DHA: 
PIC: 
PGU: 
LEL: 
SPAA: 
CAL: 
CTP: 
CDU: 
COT: 
CTEN: 
YLI: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_1290014(AO090026000726) AOR_1_1550054(AO090011000918)
ANG: 
ANI_1_306014(An01g02320) ANI_1_48044(An05g00370)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
ZTR: 
PFJ: 
BCOM: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
LBC: 
MPR: 
CCI: 
SCM: 
UMA: 
MGL: 
PGR: 
MBR: 
DDI: 
DPP: 
DFA: 
EHI: 
EHI_124520 EHI_124610(42.t00004) EHI_137700(64.t00006)
EDI: 
ACAN: 
PIF: 
EHX: 
TBR: 
TCR: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Colicelli J
  Title
Human RAS superfamily proteins and related GTPases.
  Journal
Sci STKE 2004:RE13 (2004)
Reference
  Authors
Wolfman A
  Title
Ras isoform-specific signaling: location, location, location.
  Journal
Sci STKE 2001:pe2 (2001)
Reference
  Authors
Olson MF, Marais R
  Title
Ras protein signalling.
  Journal
Semin Immunol 12:63-73 (2000)

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