KEGG ORTHOLOGY: K07881

ORTHOLOGY: K07881

Entry

K07881                      KO

Symbol

RAB14

Name

Ras-related protein Rab-14

Pathway

map04148

Efferocytosis

map04152

AMPK signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K07881  RAB14; Ras-related protein Rab-14
09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K07881  RAB14; Ras-related protein Rab-14
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K07881  RAB14; Ras-related protein Rab-14
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K07881  RAB14; Ras-related protein Rab-14
   04031 GTP-binding proteins
    K07881  RAB14; Ras-related protein Rab-14
Membrane trafficking [BR:ko04131]
Protein recycling
  Rab GTPases and associated proteins
   Rab GTPases
    K07881  RAB14; Ras-related protein Rab-14
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K07881  RAB14; Ras-related protein Rab-14
  Exosomal proteins of other body fluids (saliva and urine)
   K07881  RAB14; Ras-related protein Rab-14
  Exosomal proteins of colorectal cancer cells
   K07881  RAB14; Ras-related protein Rab-14
GTP-binding proteins [BR:ko04031]
Small (monomeric) G-proteins
  Rab Family
   Rab2/4/14 [OT]
    K07881  RAB14; Ras-related protein Rab-14

Genes

HSA:	51552(RAB14)

PTR:	744531(RAB14)

PPS:	100988238(RAB14)

GGO:	101127537(RAB14)

PON:	100461766(RAB14)

NLE:	100607466(RAB14)

HMH:	116475607(RAB14)

MCC:	699837(RAB14)

MCF:	102123446(RAB14)

MTHB:

126937968

MNI:	105487151(RAB14)

CSAB:

103218911(RAB14)

CATY:

105600232(RAB14)

PANU:

100999893(RAB14)

TGE:	112607807(RAB14)

MLEU:

105546330(RAB14)

RRO:	104655848(RAB14)

RBB:	108537090(RAB14)

TFN:	117098743(RAB14)

PTEH:

111550336(RAB14)

CANG:

105501434(RAB14)

CJC:	100390205(RAB14)

SBQ:	101040547(RAB14)

CIMI:

108285850(RAB14)

CSYR:

103258000(RAB14)

MMUR:

105875128(RAB14)

LCAT:

123646266(RAB14)

PCOQ:

105826429(RAB14)

OGA:	100963383(RAB14)

MMU:	68365(Rab14)

MCAL:

110312458(Rab14)

MPAH:

110317664(Rab14)

RNO:	94197(Rab14)

MCOC:

116090058(Rab14)

ANU:	117703347(Rab14)

MUN:	110558637(Rab14)

CGE:	100751954(Rab14)

MAUA:

101844150(Rab14) 121143985

PROB:

127222818(Rab14)

PLEU:

114704702(Rab14)

MORG:

121438031 121450991 121463164(Rab14)

MFOT:

126491265

AAMP:

119819110(Rab14)

NGI:	103734491(Rab14)

HGL:	101709151(Rab14)

CPOC:

100722861(Rab14)

CCAN:

109701407 109701429(Rab14)

DORD:

105996159(Rab14)

DSP:	122107042(Rab14)

PLOP:

125347911(Rab14)

NCAR:

124964388

MMMA:

107152129(Rab14)

OCU:

100338597

OPI:	101532319(RAB14)

TUP:	102472540(RAB14)

GVR:	103591007(RAB14)

CFA:	474818(RAB14)

CLUD:

112650435(RAB14)

VVP:	112923110(RAB14)

VLG:	121494676(RAB14)

NPO:	129494681(RAB14)

AML:	100482916(RAB14)

UMR:	103670369(RAB14)

UAH:	113266356(RAB14)

UAR:	123788018(RAB14)

ELK:

111145662

LLV:

125083240

MPUF:

101680459(RAB14)

MNP:	132024459(RAB14)

MLK:	131812291(RAB14)

NVS:	122917301(RAB14)

ORO:	101365137(RAB14)

EJU:	114212771(RAB14)

ZCA:	113935030(RAB14)

MLX:	118017744(RAB14)

NSU:	110581429(RAB14)

LWW:	102729948(RAB14)

FCA:	101087882(RAB14)

PYU:	121034918(RAB14)

PCOO:

112870172(RAB14)

PBG:	122474530(RAB14)

PVIV:

125150342(RAB14)

LRUF:

124503660

PTG:	102963518(RAB14)

PPAD:

109269882(RAB14)

PUC:

125920924

AJU:

106986618

HHV:	120233416(RAB14)

BTA:	539180(RAB14)

BOM:	102288154(RAB14)

BIU:	109563413(RAB14)

BBUB:

102402669(RAB14)

BBIS:

104994762(RAB14)

CHX:	100860798(RAB14)

OAS:	101121568(RAB14)

BTAX:

128052019(RAB14)

ODA:	120864289(RAB14)

CCAD:

122431649(RAB14)

MBEZ:

129557218(RAB14)

SSC:	595112(RAB14)

CFR:	102510331(RAB14)

CBAI:

105065264(RAB14)

CDK:	105104447(RAB14)

VPC:	102543802(RAB14)

BACU:

103008535(RAB14)

BMUS:

118896751(RAB14)

LVE:	103084850(RAB14)

OOR:	101278887(RAB14)

DLE:	111177268(RAB14)

PCAD:

102977867(RAB14)

PSIU:

116754934(RAB14)

NASI:

112411309(RAB14)

ECB:	100067611(RAB14)

EPZ:	103555548(RAB14)

EAI:	106824190(RAB14)

MYB:	102264076(RAB14)

MYD:	102775092(RAB14)

MMYO:

118667118(RAB14)

MLF:	102416874(RAB14)

PKL:	118716117(RAB14)

EFUS:

103295682(RAB14)

MNA:	107537662(RAB14)

DRO:	112306617(RAB14)

SHON:

118995983(RAB14)

AJM:	119046894(RAB14)

PDIC:

114511155(RAB14)

PHAS:

123819782(RAB14)

MMF:	118629624(RAB14)

PPAM:

129079307(RAB14)

HAI:	109385729(RAB14)

RFQ:	117031854(RAB14)

PALE:

102893098(RAB14)

PGIG:

120605768(RAB14)

PVP:	105292667(RAB14)

RAY:	107516310(RAB14)

MJV:	108398369(RAB14)

TOD:	119230523(RAB14)

SARA:

101551089(RAB14)

SETR:

126008805(RAB14)

LAV:	100676213(RAB14)

TMU:

101349795

ETF:	101637882(RAB14)

DNM:	101421755(RAB14)

MDO:	100015716(RAB14)

GAS:	123237378(RAB14)

SHR:	100929185(RAB14)

AFZ:

127550535

PCW:	110211343(RAB14)

OAA:	100081980(RAB14)

GGA:	417119(RAB14)

PCOC:

116234355(RAB14)

MGP:	100546317(RAB14)

CJO:	107321801(RAB14)

TPAI:

128074090(RAB14)

LMUT:

125702463(RAB14)

NMEL:

110406969(RAB14)

APLA:

101793367(RAB14)

ACYG:

106040710(RAB14)

CATA:

118252327(RAB14)

AFUL:

116496815(RAB14)

TGU:	100190420(RAB14)

LSR:	110477653(RAB14)

SCAN:

103818942(RAB14)

PMOA:

120512397(RAB14)

OTC:	121336835(RAB14)

PRUF:

121362415(RAB14)

GFR:	102036083(RAB14)

FAB:	101820561(RAB14)

OMA:	130260233(RAB14)

PHI:	102111219(RAB14)

PMAJ:

107212148(RAB14)

CCAE:

111937087(RAB14)

CCW:	104688368(RAB14)

CBRC:

103623113(RAB14)

ETL:	114058512(RAB14)

ZAB:	102064595(RAB14)

ACHL:

103800109(RAB14)

SVG:	106855410(RAB14)

MMEA:

130577524(RAB14)

HRT:	120761637(RAB14)

FPG:	101918436(RAB14)

FCH:	102053073(RAB14)

CLV:	102086366(RAB14)

EGZ:	104135213(RAB14)

NNI:	104023215(RAB14)

PCRI:

104025416(RAB14)

PLET:

104614990(RAB14)

EHS:	104517269(RAB14)

PCAO:

104050124(RAB14)

ACUN:

113486457(RAB14)

TALA:

104362760(RAB14)

PADL:

103915244(RAB14)

AFOR:

103900023(RAB14)

ACHC:

115335041(RAB14)

HALD:

104323264(RAB14)

HLE:	104833827(RAB14)

AGEN:

126052051

GCL:

127023546

CCRI:

104155822(RAB14)

CSTI:

104551091(RAB14)

CMAC:

104487056(RAB14)

MUI:	104534516(RAB14)

BREG:

104633815(RAB14)

FGA:	104070726(RAB14)

GSTE:

104251439(RAB14)

LDI:	104352880(RAB14)

MNB:	103777991(RAB14)

OHA:	104335124(RAB14)

NNT:	104407483(RAB14)

SHAB:

115617238(RAB14)

DPUB:

104306494(RAB14)

PGUU:

104468706(RAB14)

ACAR:

104518926(RAB14)

CPEA:

104389797(RAB14)

AVIT:

104281412(RAB14)

CVF:	104292843(RAB14)

RTD:	128917459(RAB14)

CUCA:

104066851(RAB14)

TEO:	104370585(RAB14)

BRHI:

104491542(RAB14)

AAM:	106482003(RAB14)

AROW:

112964355(RAB14)

NPD:	112955948(RAB14)

TGT:	104575834(RAB14)

DNE:	112979910(RAB14)

SCAM:

104148070(RAB14)

ASN:	102384002(RAB14)

AMJ:	102576300(RAB14)

CPOO:

109314039(RAB14)

GGN:	109293055(RAB14)

PSS:	102461544(RAB14)

CMY:	102947976(RAB14)

CCAY:

125623279(RAB14)

DCC:	119844050(RAB14)

CPIC:

101953727(RAB14)

TST:	117889449(RAB14)

CABI:

116817400(RAB14)

MRV:	120386586(RAB14)

ACS:	100553414(rab14)

ASAO:

132763674(RAB14)

PVT:	110082941(RAB14) 110090973

SUND:

121937032(RAB14)

PBI:	103060427(RAB14)

PMUR:

107295374(RAB14)

CTIG:

120300712(RAB14)

TSR:	106553528(RAB14)

PGUT:

117665097(RAB14)

APRI:

131185971(RAB14)

PTEX:

113443764(RAB14)

NSS:	113426854(RAB14)

VKO:	123028272(RAB14)

PMUA:

114588758(RAB14) 114600155

PRAF:

128406846(RAB14)

ZVI:	118084103(RAB14) 118089800

HCG:	128339034(RAB14)

GJA:	107114380(RAB14)

STOW:

125442194(RAB14)

EMC:	129342434(RAB14)

XLA:	108698208(rab14.L) 494665(rab14.S)

XTR:	493231(rab14)

NPR:	108793654(RAB14)

RTEM:

120910918 120913804(RAB14)

BBUF:

120977873(RAB14)

MUO:	115472994(RAB14)

GSH:	117368023(RAB14)

DRE:	373104(rab14) 393656(rab14l)

SRX:	107729136 107731032 107740814 107745368

SANH:

107665037 107670386 107674917 107688628

SGH:	107566859 107587668 107595498 107597932

CCAR:

109057557 109063244

CAUA:

113049717 113080184 113084571

CGIB:

127957422 127992848 127996674

PTET:

122343124(rab14l) 122345258(rab14)

LROH:

127164943(rab14) 127166000(rab14l)

OMC:	131540038(rab14l) 131540181(rab14)

PPRM:

120472019(rab14) 120472311(rab14l)

RKG:	130071554(rab14) 130079691

MAMB:

125267852(rab14l) 125267973(rab14)

CIDE:

127512618 127512687

MASI:

127419495 127422886 127436165 127440214

TROS:

130545944(rab14) 130565303(rab14l)

TDW:	130419756(rab14) 130420155(rab14l)

MANU:

129440758(rab14l) 129440968(rab14)

IPU:	108255506 108259986(rab14l)

IFU:	128603324(rab14l) 128625543

PHYP:

113531357 113537055

SMEO:

124378767(rab14l) 124380767

TFD:	113634156(rab14l) 113653313

TVC:	132840763(rab14l) 132854511

AMEX:

103026976 103045876

CMAO:

118814535(rab14l) 118826943(rab14)

EEE:	113573055 113583946

CHAR:

105889591(rab14l) 105892623

TRU:	101064581 101069277

TFS:	130516886(rab14l) 130526293

TNG:	GSTEN00017200G001 GSTEN00037336G001 GSTEN00037406G001

LCO:	104924883(rab14) 104937950

NCC:	104956367(rab14) 104959907

TBEN:

117472457 117476828(rab14l)

CGOB:

115013069 115016838(rab14)

PGEO:

117452175 117456026(rab14l)

GACU:

117535025 117538879(rab14l)

EMAC:

134867977(rab14l) 134874055

ELY:	117252552 117269922(rab14l)

EFO:	125889898 125905989(rab14l)

PLEP:

121959782(rab14l) 121960730

SLUC:

116035158(rab14l) 116056732

ECRA:

117945302 117959708(rab14l)

ESP:	116689983 116704536

PFLV:

114555264 114571064

GAT:	120830437 120832039(rab14l)

PPUG:

119225479 119227136(rab14l)

AFB:	129100794 129102097(rab14l)

CLUM:

117736044 117740541(rab14l)

PSWI:

130197063 130204913(rab14l)

MSAM:

119891604 119914668(rab14l)

SCHU:

122865162(rab14l) 122876793

CUD:	121509603 121525279(rab14l)

ALAT:

119019109 119030049(rab14l)

MZE:	101475079(rab14) 101478210

ONL:	100697822 100710169

OAU:	116315343 116322433(rab14l)

OLA:	101162540 101167092

OML:	112142073 112162990(rab14l)

CSAI:

133451354 133455185(rab14l)

XMA:	102230652(rab14) 102234551

XCO:	114144833 114149597(rab14)

XHE:	116723813(rab14) 116729823

PRET:

103470772 103473793

PFOR:

103131877 103149576(rab14)

PLAI:

106935339 106944531(rab14)

PMEI:

106906800 106924240(rab14)

GAF:	122819485(rab14l) 122828571

PPRL:

129366082 129366416(rab14l)

CVG:	107084653 107088443(rab14)

CTUL:

119776100 119781546(rab14l)

GMU:	124872928(rab14l) 124878401

NFU:	107374090 107386141

KMR:	108230986(rab14l) 108245888

ALIM:

106527788 106532565(rab14)

NWH:	119413771 119413772 119424927(rab14l)

AOCE:

111564024 111578184(rab14)

MCEP:

124996913(rab14l) 125012822(rab14)

CSEM:

103390174 103398011

POV:	109626265 109646152

SSEN:

122758244(rab14l) 122768355

HHIP:

117768370 117771274(rab14l)

HSP:	118114746 118125413(rab14l)

SMAU:

118284472(rab14l) 118313556

LCF:	108875314 108888950(rab14l)

SDU:	111236936 111237781(rab14)

SLAL:

111653115 111664731(rab14)

XGL:	120805207 120806475(rab14l)

HCQ:	109513484 109514693

SSCV:

125979914 125994190

SBIA:

133491196(rab14l) 133499111

PEE:	133400236 133414255(rab14l)

PTAO:

133475827 133489948(rab14l)

BPEC:

110160515(rab14) 110166400

MALB:

109957369 109960592

BSPL:

114861675 114866571(rab14l)

SJO:	128364617 128364618 128380516(rab14l)

SASA:

100195252(rab14) 106563285(RAB14) 106587009

STRU:

115159564 115167681 115204070

OTW:	112219307 112230991(rab14l) 112248905(rab14)

OMY:	110509796(rab14l) 110523590 110526078(rab14)

OGO:	124006698 124033998(rab14) 124048966

ONE:	115101171 115111975

OKI:	109873831 109879861 109880089

OKE:	118373068 118385299 118393583(rab14)

SALP:

111961612 111964019 111974061

SNH:	120021212 120025693 120044780(rab14)

CCLU:

121541668 121582512 121584584(rab14)

ELS:	105015017 105027810

SFM:	108922677 108938536

PKI:	111842686 111843475

AANG:

118207108(rab14l) 118213003

LOC:	102685360(rab14)

PSPA:

121309713

ARUT:

117396933 117422065

PSEX:

120536005

LCM:	102352449(RAB14)

CMK:

RTP:

CPLA:

HOC:

LERI:

PMRN:

116944838(RAB14)

LRJ:	133341717(RAB14)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:

DME:	Dmel_CG4212(Rab14)

DER:	6540653 6546744

DSE:

6611267

DSI:	Dsimw501_GD23961(Dsim_GD23961)

DYA:	Dyak_GE19031

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI12880

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:	108367106 108378925

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ004858

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:	100119081(Rab14)

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:	659169(Rab14)

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_214204

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:	119828565 119839893

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CFEL:

CCRN:

API:	100159414(Rab14)

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

MQU:	129000899 129004643

PHU:	Phum_PHUM137540

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_231914

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

ISC:

DSV:	119437181 119437182

RSAN:

RMP:

VDE:

VJA:

TUT:

DFR:

CSCU:

PTEP:

ABRU:

129965642 129965981 129978846

UDV:

129234156

SDM:	118190629 118204156

LPOL:

106460956 106462712 106475290

CEL:	CELE_K09A9.2(rab-14)

CBR:	CBG_07733(Cbr-rab-14)

CRQ:	GCK72_025514

NAI:	NECAME_01544

BMY:	BM_BM4940(Bma-rab-14)

LOA:	LOAG_09206

TSP:	Tsp_10926 Tsp_12374

HRO:	HELRODRAFT_184934

LGI:	LOTGIDRAFT_198201

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:	110447039 110464888

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:	106157238 106159181

SMM:	Smp_004910

SHX:	MS3_00004373(RAB14)

OVI:	T265_12666

EGL:

EGR_02477

NVE:

5515241

EPA:	110244792 114574417

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_49865

AQU:

100636499

MBR:	MONBRDRAFT_21678

SRE:	PTSG_10676

DDI:	DDB_G0281337(rab14)

DPP:	DICPUDRAFT_92215(rab14)

DFA:	DFA_00344(rab14) DFA_03633 DFA_11884

ACAN:

ACA1_279530

GTT:	GUITHDRAFT_94864

TCR:	504741.240 511621.120

LMA:	LMJF_07_0560

LIF:	LINJ_07_0610

LDO:	LDBPK_070610

LMI:	LMXM_07_0560

LBZ:	LBRM_07_0620

LPAN:

LPMP_070600

NGR:	NAEGRDRAFT_59420

TVA:	TVAG_2v0210040 TVAG_2v0358170 TVAG_2v0383180 TVAG_2v0419120 TVAG_2v0441080 TVAG_2v0556620 TVAG_2v0616040 TVAG_2v0623470 TVAG_2v0919860 TVAG_2v0948980

LOKI:

Lokiarch_01690 Lokiarch_36400 Lokiarch_52350

» show all

Reference

PMID:17082769

Authors

Kyei GB, Vergne I, Chua J, Roberts E, Harris J, Junutula JR, Deretic V

Title

Rab14 is critical for maintenance of Mycobacterium tuberculosis phagosome maturation arrest.

Journal

EMBO J 25:5250-9 (2006)
DOI:10.1038/sj.emboj.7601407

Sequence

[mmu:68365]

Reference

PMID:22595670

Authors

Linford A, Yoshimura S, Nunes Bastos R, Langemeyer L, Gerondopoulos A, Rigden DJ, Barr FA

Title

Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells.

Journal

Dev Cell 22:952-66 (2012)
DOI:10.1016/j.devcel.2012.04.010

Sequence

[hsa:51552]

All links

Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Gene (2903)   
   KEGG GENES (828)   
   KEGG MGENES (76)   
   RefGene (1988)   
   OC (11)   
Literature (2)   
   PubMed (2)   
All databases (2913)   

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